www.mt.com Open in urlscan Pro
163.171.128.148  Public Scan

Form analysis
10 forms found in the DOM

<form>
  <div class="mt_search_input_wrapper" data-mobile-ks-placeholder="Search Products and Solutions…">
    <div class="mt_search_input-field"><label for="st-default-search-box" style="display:none;">Search</label><input type="text" class="st-default-search-input search-field" id="st-default-search-box" placeholder="Search..." autocomplete="off"
        autocorrect="off" autocapitalize="off"><span class="input_icon-clear" style="display: none;"><i></i></span></div>
    <div class="mt_search_input-suggestions">
      <h5 class="mt_search-suggestions-label">Search suggestions</h5>
      <ul>
        <li>ph meter</li>
        <li>balance</li>
        <li>conductivity</li>
        <li>counting platform scale</li>
        <li>ind570</li>
      </ul>
    </div>
  </div>
</form>

---

GET /us/en/home.html

<form id="logoutLink" action="/us/en/home.html" method="get"><input type="hidden" name="formType" value="logout">
  <ul>
    <li><a class="logoutLink_editProfileAnchor" href="/us/en/home/registered_user_services/profile-dashboard.html">My mt.com</a></li>
    <li><a class="logoutLink_logoutAnchor" href="#" onclick="logout();">Logout</a></li>
  </ul>
</form>

---

GET /us/en/home/applications/L1_AutoChem_Applications/L2_Formulation.fb.1.cs.html?abcl=1

<form class="fb-a-button-wrapper moreinfo_btn translation-wrap" method="get" action="/us/en/home/applications/L1_AutoChem_Applications/L2_Formulation.fb.1.cs.html?abcl=1"><button class="fb-button-p5a blue resize-translated-button"
    id="translation-wordbreak" data-swiftype-index="false"> Request Info </button></form>

---

GET /us/en/home/applications/L1_AutoChem_Applications/L2_Formulation.fb.1.c.11.html?abcl=2

<form class="fb-a-button-wrapper getquote_btn translation-wrap" method="get" action="/us/en/home/applications/L1_AutoChem_Applications/L2_Formulation.fb.1.c.11.html?abcl=2"><button class="fb-button-p5a resize-translated-button"
    id="translation-wordbreak" data-swiftype-index="false"> Get a Quote </button></form>

---

GET /us/en/home/applications/L1_AutoChem_Applications/L2_Formulation.fb.overviewafpar.standalonemoodimage_.feedbackb.html

<form method="get" action="/us/en/home/applications/L1_AutoChem_Applications/L2_Formulation.fb.overviewafpar.standalonemoodimage_.feedbackb.html"><button class="fb-button-p5a"> Request More Information </button></form>

---

GET /us/en/home/applications/L1_AutoChem_Applications/L2_Formulation.fb.overviewafpar.standalonemoodimage__912840543.feedbackb.html

<form method="get" action="/us/en/home/applications/L1_AutoChem_Applications/L2_Formulation.fb.overviewafpar.standalonemoodimage__912840543.feedbackb.html"><button class="fb-button-p5a"> Request More Information </button></form>

---

GET /us/en/home/applications/L1_AutoChem_Applications/L2_Formulation/Formulation_Dissolution.fb.1.cs.13.html

<form class="fb-a-button-wrapper moreinfo_btn familyMobile_requestInfo" method="get" action="/us/en/home/applications/L1_AutoChem_Applications/L2_Formulation/Formulation_Dissolution.fb.1.cs.13.html"><button
    data-href="/content/us/en/home/applications/L1_AutoChem_Applications/L2_Formulation/Formulation_Dissolution.fb.1.cs.13.html" class="fb-button-p5a blue small" data-swiftype-index="false"> Request Info </button></form>

---

GET /us/en/home/applications/L1_AutoChem_Applications/L2_Formulation/Milling.fb.1.cs.13.html

<form class="fb-a-button-wrapper moreinfo_btn familyMobile_requestInfo" method="get" action="/us/en/home/applications/L1_AutoChem_Applications/L2_Formulation/Milling.fb.1.cs.13.html"><button
    data-href="/content/us/en/home/applications/L1_AutoChem_Applications/L2_Formulation/Milling.fb.1.cs.13.html" class="fb-button-p5a blue small" data-swiftype-index="false"> Request Info </button></form>

---

GET /us/en/home/applications/L1_AutoChem_Applications/L2_Formulation.fb.1.cs.html?abcl=1

<form class="fb-a-button-wrapper moreinfo_btn translation-wrap" method="get" action="/us/en/home/applications/L1_AutoChem_Applications/L2_Formulation.fb.1.cs.html?abcl=1"><button class="fb-button-p5a blue resize-translated-button"
    id="translation-wordbreak" data-swiftype-index="false"> Request Info </button></form>

---

GET /us/en/home/applications/L1_AutoChem_Applications/L2_Formulation.fb.1.c.11.html?abcl=2

<form class="fb-a-button-wrapper getquote_btn translation-wrap" method="get" action="/us/en/home/applications/L1_AutoChem_Applications/L2_Formulation.fb.1.c.11.html?abcl=2"><button class="fb-button-p5a resize-translated-button"
    id="translation-wordbreak" data-swiftype-index="false"> Get a Quote </button></form>

---

Text Content

___

 * Products & Solutions
   
   Laboratory Weighing
   
   Industrial Scales and Load Cell Systems
   
   Product Inspection
   
   Rainin Liquid Handling Solutions
   
   Process Analytics
   
   Truck Scales / Weighbridges and Dimensioning
   
   Analytical Instruments
   
   Automated Reactors and In-Situ Analysis
   
   Retail Weighing Scales
   
   Browse our product offerings here
   
   Analytical Balances
   
   Precision Balances
   
   Microbalance & Ultra Micro Balances
   
   Moisture Analyzers
   
   Solutions for Laboratory Weighing Automation
   
   Software for Laboratory Weighing
   
   Test Weights
   
   Jewelry Scales and Balances
   
   Mass Comparators
   
   Scale Indicator and Scale Controller Systems
   
   Bench Scales and Portable Scales
   
   Platform Scale
   
   Floor Scales and Heavy-Duty Scales
   
   Weigh Modules, Load Cells, Weight Sensors
   
   Explosion Proof Scale / Hazardous Area Scales
   
   Calibrating Scale / Scale Weights
   
   Scale Driver / Software
   
   Printers and Peripherals
   
   Checkweigher Solutions
   
   Metal Detection - Safeline
   
   Safeline X-ray Inspection Systems
   
   Track & Trace Solutions
   
   Vision Inspection Systems
   
   ProdX™ Quality Management Software for Process Data Management
   
   Pipettes
   
   Pipette Tips
   
   High-Throughput Pipetting
   
   Pipette Management
   
   Analytical Transmitters
   
   pH Analyzers & ORP Analyzers
   
   CO2, Ozone & Dissolved Oxygen Analyzers
   
   Conductivity Analyzers
   
   TOC Analyzers & Bioburden Analyzers
   
   Industrial Process Gas Analyzers
   
   Turbidity Meters & Sensors
   
   On-Line Water Chemistry Analyzers
   
   Process Adaptions and Cleaning Systems
   
   Truck Scale Systems and Solutions
   
   Pallet and Parcel Dimensioners
   
   Dynamic Parcel Weighing
   
   Rail Scales / Railroad Weighing Scales
   
   Postal Scales and Shipping Scales
   
   Forklift Scales
   
   Pallet Jack Scales
   
   Thermal Analysis Excellence
   
   Lab pH Instruments
   
   Titrators
   
   Melting Point Apparatus
   
   Dropping / Softening Point Apparatus
   
   Density Meter
   
   Refractometer / Brix Meter
   
   Spectrophotometer UV Vis
   
   Laboratory Software Solutions
   
   ReactIR In-situ Reaction Analysis
   
   Automated Synthesis & Process Development
   
   Automated Sampling for Chemical Reactions
   
   Reaction Calorimeters
   
   Particle Size Analyzers
   
   Raman Spectrometers
   
   iC Software Suite
   
   Counter Scales
   
   Self-Service Scales
   
   Wrapping and Weigh Price Labeling
   
   Checkout Scales
   
   Hanging Scales
   
   Retail Software
   
   --------------------------------------------------------------------------------
   
   Applications
   
   Applications
   
   Applications
   
   Applications
   
   Applications
   
   Applications
   
   Applications
   
   Service
   
   Service
   
   Service
   
   Service
   
   Service
   
   Service
   
   Service
   
   Service
   
   Service
   
   
 * Industries
    * Chemical
    * Pharma and Biotech Solutions
    * Food and Beverages Solutions
    * Academia and Education
    * Testing Labs and Health Institutes
    * Metal, Plastic and Electronics Components
    * Raw Materials & Jewelry
    * Engineering, Machinery & Equipment Manufacturing
    * Retail
    * Transport and Logistics
    * Utilities & Municipalities

 * Services & Support
    * Service Offerings
    * Register Your Product
    * Technical Support
    * eProcurement
    * Track Your Order

 * Events & Expertise
    * Live Events
    * Seminars & Training
    * Trade Shows & Exhibitions
    * Live Webinars
    * Expertise Library
    * White Papers & Literature
    * Technical Documentation
    * On Demand Webinars
    * Videos

 * About Us
    * Jobs & Careers
    * Sustainability
    * Business Description
    * Digitalization
    * Global Presence
    * Innovation & Quality
    * Management
    * Investor Relations
    * Newsroom

 * Contact Us

Search

SEARCH SUGGESTIONS

 * ph meter
 * balance
 * conductivity
 * counting platform scale
 * ind570


Welcome, {mt:userTitle/} {mt:lastName/}

 * Login / Registration

 * My mt.com
 * Logout



Select Country



By Application AutoChem Applications Particle Size in Formulations


PARTICLE SIZE IN FORMULATIONS


MEASURE PARTICLES AND DROPLETS IN SOLID AND LIQUID FORMULATIONS TO OPTIMIZE
PROCESS DEVELOPMENT

Request Info
/content/us/en/home/applications/L1_AutoChem_Applications/L2_Formulation.fb.1.c.11.html?abcl=2
Get a Quote

Please describe your project. Request Quote or Info Call for Quote Request
InfoGet a Quote
 * Overview
 * Applications
 * Publications
 * Related Products
 * More Information







CONTROLLING PARTICLE SIZE


IN FORMULATIONS & PRODUCT DEVELOPMENT

Particle and droplet size directly influence the bioavailibility and
manufacturability of liquid and solid formulations. For example, the development
of topical products requires tight control of droplet size and a clear
understanding of how the process parameters chosen at each scale influences
stability. Tablets break apart into small particles  during dissolution testing 
and the rate of disintegration directly influences Active Pharmaceutical
Ingredients (API) release rate. Suspensions used to fill meter dose inhalers
require tight control over particle size to ensure efficacy for the patient.


SOLID ORAL DOSAGE FORMULATION


QUANTIFYING DISSOLUTION & DISINTEGRATION

Quantifying tablet disintegration profiles in situ and in real time enables
scientists to reliably understand the breakage and dispersion mechanisms that
govern Active Pharmaceutical Ingredient (API) release rates. This essential
process knowledge can support the prediction of in vivo drug release profiles
during formulation development, and can help identify the root cause of
inconsistencies during release testing.

The resulting mechanistic information complements traditional offline
dissolution testing methods, and can support the development and release of
bioavailable, stable, and manufacturable dosage forms.

ParticleTrack with FBRM technology continuously monitors changes in particle
size and count as capsules an tablets disintegrate and dissolve. The resulting
mechanistic information complements traditional offline dissolution testing
methods and can support the development and release of bioavailable, stable and
manufacturable dosage forms.

ParticleTrack applications include:

 * Quality by Design
 * Disintegration Kinetics
 * Release Mechanism Determination
 * Risk Assessment
 * FDA Compliance
 * Tablet Dissolution for Process Understanding

Request More Information


MONITOR TABLET & GRANULE DISINTEGRATION


SOLID ORAL DOSAGE FORM DEVELOPMENT

Mark Menning of the Nucleo Life Sciences presents the role of in-process
particle measurement to complement traditional API dissolution studies. The use
of in situ particle size and count measurement illustrates efforts to develop
process understanding for solid oral dosage form development. This is
supplemented by case studies from Amgen, AstraZeneca, and Vertex who use this
approach.

 * Monitor Tablet & Granule Disintegration by Mark Menning PhD


EMULSION DROPLET SIZE AND STABILITY


CHOOSE OPTIMIZED PROCESS PARAMETERS

Emulsion droplet size and stability are critical parameters to consider during
the development of a topical or micro-encapsulated product. Characterizing
droplet size effectively allows scientists to solve process bottlenecks and
improve product quality. Traditionally, scientists have relied on offline
particle size analyzers to perform emulsion and suspension characterization.
Offline analysis typically requires sample preparation and sample dilution prior
to analysis which, in the case of emulsions, can significantly change the
droplet size in an emulsion sample within the time required for preparation and
analysis.

The emergence of Process Analytical Technologies (PAT) allows scientists and
engineers to track the rate and degree of change in droplet systems as they
naturally exists in process without the need for sampling or sample preparation:

 * Process Understanding for Emulsions
 * Monitoring Multi-Phase systems (Particles and Droplets)
 * Scaling-Up Emulsions


USING PAT TO OPTIMIZE EMULSIONS

Four case studies present how inline Process Analytical Technologies were used
to understand, control, and optimize emulsion processing. Topics include
creation of  fit-for-purpose droplets, observation of multi-phase systems, and
scale-up.


 * White Paper: PAT For Emulsions


INLINE PROCESS ANALYTICAL TECHNOLOGY


MEASURE PARTICLE SIZE IN REAL TIME

ParticleTrack and ParticleView are probe-based tools that measure changes to
particle size, shape, and count in real time. By applying inline analysis to
formulation development, scientists can obtain comprehensive process
understanding, avoid the errors and time delay associated with offline and
ultimately develop formulations with desired attributes in the shortest possible
time.   Click Request More Information below to gain technical expertise or to
assess the fit of your application with ParticleTrack and ParticleView
technology.

Request More Information


FOCUSED BEAM REFLECTANCE MEASUREMENT


INLINE PARTICLE SIZE, COUNT, AND SHAPE

A ParticleTrack probe with FBRM technology is immersed into a flowing slurry or
droplet system with no dilution necessary. A focused laser scans the surface of
the probe window and tracks individual chord lengths - measurements of particle
size, shape, and count. This real-time measurement is presented as a
distribution and statistics (eg. mean, counts) are trended over time.


APPLICATIONS


APPLICATIONS RELATED TO SOLID AND LIQUID FORMULATIONS


Tablet Disintegration and Dissolution
Solid Oral Dosage Form Development




Liquid Suspensions and Emulsions
Particle or droplet size and stability are critical in liquid formulations of
suspensions or emulsions




Tablet Disintegration and Dissolution



See details
Request Info
 * Overview
 * Related Products

See less
Liquid Suspensions and Emulsions



See details
Request Info
 * Overview
 * Applications
 * Publications

See less


PUBLICATIONS


PUBLICATIONS ON SOLID AND LIQUID FORMULATIONS




WHITE PAPERS

PAT For Emulsions
Use PAT for emulsions and suspension characterization without the need for
sampling or sample prep.
Monitor Tablet & Granule Disintegration
The role of in-process particle measurement to complement traditional API
dissolution studies is presented. The use of particle size and count measure...
Particle Size Analysis for Process Optimization
This white paper introduces some of the most common particle size analysis
approaches and how they can be deployed for the effective delivery of high...




ON-DEMAND WEBINARS

Emulsion Formulation in Consumer Products
This webinar discusses how to optimize the emulsion formulation process in
consumer products. Inline particle size measurement is used to improve the...
Online Monitoring of MicroEncapsulation
The effect that product and process variability has on microparticle is
essential for successful development, optimization, and scale-up of an
encapsu...
De-Emulsification and Emulsification of Petroleum-Water
In Petroleum, emulsions are often necessary in upstream transfer of crude oil
and in downstream separation of oil and water in the crude oil process....
Improve Emulsion Stability
Particle or droplet size is critical to improve the stability of emulsions and
liquid formulations. Ideally, scientists and engineers accelerate their...




RELATED PRODUCTS


PARTICLE SIZE MEASUREMENT TECHNOLOGY FOR FORMULATIONS




PARTICLE SIZE ANALYZERS

Understand, Optimize & Control Particle & Droplets With Real-Time In Situ
Particle Size Analyzers

Webinars
On Demand Webinar
 * De-Emulsification and Emulsification of Petroleum-Water

 * Online Monitoring of MicroEncapsulation

 * Emulsion Formulation in Consumer Products

 * Improve Emulsion Stability








Products & Solutions

--------------------------------------------------------------------------------

Laboratory Balances

Industrial Scales

Retail Weighing Scales

Rainin Pipettes and Tips

Analytical Instruments

Automated Reactors and In Situ Analysis

Process Analytics

Inline Product Inspection

Transport and Logistics

Services & Support

--------------------------------------------------------------------------------

Service Offerings

Product Registration

Technical Support

Payment Methods

 

Events & Expertise

--------------------------------------------------------------------------------

Expertise Library  

   Literature: White    Papers, Guides, Brochures

   Technical Documentation

   On Demand Webinars

   Videos  

Live Events

   Seminars & Training

   Trade Shows & Exhibitions

   Live Webinars    
 


 

About Us

--------------------------------------------------------------------------------

Jobs & Careers
 
METTLER TOLEDO

 Sustainability

 Business Description

 Digitalization

 Global Presence

 Innovation & Quality

 Management
 
Investor Relations

Newsroom
 

Quick Links

--------------------------------------------------------------------------------

Contact Us

Search


Document Finder

Product Finder

Service Finder
 
Videos

 

 



© METTLER TOLEDO. All rights reserved.

 * Legal, Terms, Privacy
 * |Contact us
 * |Site Map
 * |Global Presence




REQUEST QUOTE OR INFO GET A QUOTE INSTANT QUOTE SOLUTION INFORMATION
PARTICLE SIZE IN FORMULATIONS






Request Info
/content/us/en/home/applications/L1_AutoChem_Applications/L2_Formulation.fb.1.c.11.html?abcl=2
Get a Quote

Please describe your project. Request Quote or Info Call for Quote Request
InfoGet a Quote
 * Overview
 * Applications
 * Publications
 * Related Products
 * More Information









PRIVACY PREFERENCE CENTER




 * YOUR PRIVACY


 * STRICTLY NECESSARY COOKIES


 * PREFERENCE COOKIES


 * STATISTICS COOKIES


 * MARKETING COOKIES

YOUR PRIVACY

When you visit any website, it may store or retrieve information on your
browser, mostly in the form of cookies. This information might be about you,
your preferences or your device and is mostly used to make the site work as you
expect it to. The information does not usually directly identify you, but it can
give you a more personalized web experience. Because we respect your right to
privacy, you can choose not to allow some types of cookies. Click on the
different category headings to find out more and change our default settings.
However, blocking some types of cookies may impact your experience of the site
and the services we are able to offer.
More information

STRICTLY NECESSARY COOKIES

Always Active

These cookies are necessary for the website to function and cannot be switched
off in our systems. They are usually only set in response to actions made by you
which amount to a request for services, such as setting your privacy
preferences, logging in or filling in forms. You can set your browser to block
or alert you about these cookies, but some parts of the site will not then work.
These cookies do not store any personally identifiable information.

PREFERENCE COOKIES

Preference Cookies


These cookies enable the website to provide enhanced functionality and
personalisation. They may be set by us or by third party providers whose
services we have added to our pages. If you do not allow these cookies then some
or all of these services may not function properly.

STATISTICS COOKIES

Statistics Cookies


These cookies allow us to count visits and traffic sources so we can measure and
improve the performance of our site. They help us to know which pages are the
most and least popular and see how visitors move around the site. All
information these cookies collect is aggregated and therefore anonymous. If you
do not allow these cookies we will not know when you have visited our site, and
will not be able to monitor its performance.

MARKETING COOKIES

Marketing Cookies


These cookies may be set through our site by our advertising partners. They may
be used by those companies to build a profile of your interests and show you
relevant adverts on other sites. They do not store directly personal
information, but are based on uniquely identifying your browser and internet
device. If you do not allow these cookies, you will experience less targeted
advertising.

Back Button


BACK



Vendor Search
Filter Button
Consent Leg.Interest
checkbox label label
checkbox label label
checkbox label label

Clear
checkbox label label
Apply Cancel
Confirm My Choices
Allow All


By clicking “Accept All Cookies”, you agree to the storing of cookies on your
device to enhance site navigation, analyze site usage, and assist in our
marketing efforts. Learn more

Accept All Cookies
Cookie Settings



Welcome to METTLER TOLEDO —
Your Global Provider of Precision Instruments and Weighing Equipment.

Is this your country or area?

Based on your IP we assume you are located in this country or area

Deutschland (de) / Germany (en)



This page is not optimized for your web browser. Consider using a different
browser or upgrade your browser to the latest version to ensure the best
experience.