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Skip to main content * Home * What is Lp(a)? * Screening * Management * Resources * Get Lp(a) Updates 8/23 283430 For PublicHCPs This site is for US Health Care Professionals Only ELEVATED LP(A) MAY BE HIDING IN YOUR PATIENT'S LIPID PROFILE ~ 1 in 5 people may inherit elevated Lp(a), a lifelong cardiovascular risk factor1-3 Get Lp(a) Updates WHAT MAKES ELEVATED LP(A) UNIQUE MAY ALSO MAKE IT A THREAT TO YOUR PATIENTS Watch this video to see what makes it so different from other cardiovascular risk factors. Read the Transcript > INTRODUCTION TO LP(A) * Lp(a) is a unique form of lipoprotein that is proatherogenic, proinflammatory, and prothrombotic at elevated levels4,5 * Large-scale genetic studies have confirmed that elevated Lp(a) is an independent and causal cardiovascular risk factor2,6-8 * Elevated Lp(a) contributes to a consistent and lifelong risk of heart attack and stroke2 UNCOVER MORE ABOUT ELEVATED LP(A) Elevated Lp(a) is one of the strongest single genetic risk factors for coronary artery disease.8 View the Data Screening for elevated Lp(a) requires only a simple blood test that can be added to any routine blood work.9 Learn More Knowing a patient's Lp(a) levels can help inform a lifetime of cardiovascular care.2,3,10-12 See How References: 1. Tsimikas S, Fazio S, Ferdinand KC, et al. NHLBI Working Group recommendations to reduce lipoprotein(a)-mediated risk of cardiovascular disease and aortic stenosis. J Am Coll Cardiol. 2018;71(2):177-192. 2. Kronenberg F, Mora S, Stroes ESG, et al. Lipoprotein(a) in atherosclerotic cardiovascular disease and aortic stenosis: a European Atherosclerosis Society consensus statement. Eur Heart J. 2022;14:43(39):3925-3946. 3. Wilson DP, Jacobson TA, Jones PH, et al. Use of lipoprotein(a) in clinical practice: A biomarker whose time has come. A scientific statement from the National Lipid Association. J Clin Lipidol. 2019;13(3):374-392. 4. Reyes-Soffer G, Ginsberg HN, Berglund L, et al; American Heart Association Council on Arteriosclerosis, Thrombosis and Vascular Biology; Council on Cardiovascular Radiology and Intervention; and Council on Peripheral Vascular Disease. Lipoprotein(a): a genetically determined, causal, and prevalent risk factor for atherosclerotic cardiovascular disease: a scientific statement from the American Heart Association. Arterioscler Thromb Vasc Biol. 2022;42(1):e48-e60. 5. Jawi MM, Frohlich J, Chan SY. Lipoprotein(a) the insurgent: a new insight into the structure, function, metabolism, pathogenicity, and medications affecting lipoprotein(a) molecule. J Lipids. 2020;2020:3491764. doi: 10.1155/2020/3491764 6. Enas EA, Varkey B, Dharmarajan TS, Pare G, Bahl VK. Lipoprotein(a): An independent, genetic, and causal factor for cardiovascular disease and acute myocardial infarction. Indian Heart J. 2019;71(2):99-112. 7. Nordestgaard BG, Chapman MJ, Ray K, et al; European Atherosclerosis Society Consensus Panel. Lipoprotein(a) as a cardiovascular risk factor: current status. Eur Heart J. 2010;31(23):2844-2853. 8. Tsimikas S. A test in context: Lipoprotein(a): Diagnosis, prognosis, controversies, and emerging therapies. J Am Coll Cardiol. 2017;69(6):692-711. 9. Farzam K, Senthilkumaran S. Lipoprotein A. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022. Updated September 2, 2022. Accessed August 22, 2023. https://www.statpearls.com/ArticleLibrary/viewarticle/130795 10. Virani SS, Koschinsky ML, Maher L, et al. Global think tank on the clinical considerations and management of lipoprotein(a): The top questions and answers regarding what clinicians need to know. Prog Cardiovasc Dis. 2022;73:32-40. 11. Willeit P, Kiechl S, Kronenberg F, et al. Discrimination and net reclassification of cardiovascular risk with lipoprotein(a): prospective 15-year outcomes in the Bruneck Study. J Am Coll Cardiol. 2014;64(9):851-860. 12. Raitakari O, Kartiosuo N, Pahkala K, et al. Lipoprotein(a) in youth and prediction of major cardiovascular outcomes in adulthood. Circulation. 2023;147(1):23-31. * Contact Us * Interest-Based Ads * Sitemap * Non-US Residents Novartis Pharmaceuticals Corporation Use of website is governed by the Terms of Use ↗ and Privacy Policy ↗. Copyright © 2023 Novartis Pharmaceuticals Corporation ↗. All rights reserved. 08/23 283430 Back to top YOU ARE ABOUT TO LEAVE UNCOVERLPA.COM You are about to leave a Novartis site and continue to an external website independently operated and not managed by Novartis Pharmaceuticals Corporation. CONTINUE TO EXTERNAL SITE YOU ARE ABOUT TO LEAVE UNCOVERLPA.COM You are now being directed to another Novartis website. CONTINUE TO EXTERNAL SITE