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Submitted URL: http://blog.biosearchtech.com/
Effective URL: https://blog.biosearchtech.com/
Submission: On November 22 via api from US — Scanned from DE
Effective URL: https://blog.biosearchtech.com/
Submission: On November 22 via api from US — Scanned from DE
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Text Content
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Written and curated by scientists for scientists, receive new articles straight to your inbox twice monthly. Your Email:* Lifecycle Stage Your browser does not support HTML5 video. New and Featured Human Healthcare Applied Agrigenomics General Science FEATURED POSTS Why circular RNA could be the next revolution in RNA therapeutics Wat's the latest in ASO and siRNA technologies? How to design mRNA therapeutics for scalable success mRNA technology played a critical role in combating COVID-19. This new class of therapeutics is a fast-emerging platform offering hope for a wide range of diseases. Read this article to learn more about the design, production and purity testing of mRNA therapeutic programmes. EXPLORE POPULAR TOPICS * Agrigenomics * Disease detection * General science * Genomics * Molecular diagnostics * Next generation sequencing (NGS) * NGS-based genotyping * Nucleic acid extraction * Nucleic acid therapeutics * Oligo synthesis and modifications * PCR-based genotyping * qPCR * RNA FISH * SARS-CoV-2 See all topics RECENT POSTS HUMAN HEALTHCARE APPLIED AGRIGENOMICS GENERAL SCIENCE * All * General science * qPCR * Genomics * Molecular diagnostics * Oligo synthesis and modifications * Agrigenomics * SARS-CoV-2 * RNA FISH * PCR-based genotyping * NGS-based genotyping * Disease detection * Next generation sequencing (NGS) * Nucleic acid therapeutics * Nucleic acid extraction THE BIOSEARCHTECH BLOG Choose category General science qPCR Genomics Molecular diagnostics Oligo synthesis and modifications Agrigenomics SARS-CoV-2 RNA FISH PCR-based genotyping NGS-based genotyping Disease detection Next generation sequencing (NGS) Nucleic acid therapeutics Nucleic acid extraction Choose category▾ * Choose category * General science * qPCR * Genomics * Molecular diagnostics * Oligo synthesis and modifications * Agrigenomics * SARS-CoV-2 * RNA FISH * PCR-based genotyping * NGS-based genotyping * Disease detection * Next generation sequencing (NGS) * Nucleic acid therapeutics * Nucleic acid extraction Most popular Disease detection Nucleic acid therapeutics WHY CIRCULAR RNA COULD BE THE NEXT REVOLUTION IN RNA THERAPEUTICS Posted on Wed, Nov 22, 2023 @ 10:47 AM While RNA-based therapeutics are taking the biotechnology world by storm following the rapid development of the... Read more Oligo synthesis and modifications Nucleic acid therapeutics SYNTHESIZING YOUR OWN OLIGONUCLEOTIDES: FAQS Posted on Tue, Nov 07, 2023 @ 08:30 AM Considering bringing oligo synthesis in-house? Here are some commonly asked questions that we receive, grouped into... Read more Molecular diagnostics HOW TO DESIGN MRNA THERAPEUTICS FOR SCALABLE SUCCESS Posted on Thu, Oct 26, 2023 @ 11:09 AM The recent Nobel Prize awarded to Katalin Karikó and Drew Weissman underlined the impact their breakthroughs in mRNA... Read more Agrigenomics NGS-based genotyping INCREASING LIVESTOCK BREEDING PROFITABILITY WITH GENOMIC SELECTION Posted on Tue, Oct 17, 2023 @ 01:23 PM HOW DOES GENOMIC SELECTION INCREASE PROFITABILITY? Livestock farmers’ and breeders’ profitability is directly related... Read more Molecular diagnostics Disease detection THE RISE OF LAMP FOR RAPID POINT-OF-NEED TESTING Posted on Thu, Sep 28, 2023 @ 02:30 PM As the world scrambled to rapidly expand PCR testing capacity in 2020, it became increasingly clear that there was a... Read more Oligo synthesis and modifications “CLICK” YOUR WAY TOWARDS DISCOVERY AND INNOVATION Posted on Fri, Sep 08, 2023 @ 04:08 AM Labelling, linking or modifying biomolecules used to be a laborious process, requiring customised complex synthetic... Read more Molecular diagnostics qPCR MINIMISING ANTIBIOTIC DEPENDENCY FOR TREATING UTIS AND STIS Posted on Tue, Aug 15, 2023 @ 04:40 AM Antimicrobial resistance (AMR) across bacterial species is developing rapidly, compounded by the improper use of... Read more Agrigenomics NGS-based genotyping US DEPT OF AGRICULTURE DIVES INTO BLUEBERRY AND CRANBERRY GENOTYPING Posted on Fri, Jul 28, 2023 @ 10:20 AM Every year over 1.5 million tonnes of blueberries and over half a million tonnes of cranberries are produced. This is... Read more Oligo synthesis and modifications Nucleic acid therapeutics WHAT’S THE LATEST IN ASO AND SIRNA TECHNOLOGIES? Posted on Fri, Jul 07, 2023 @ 10:40 AM Over the last few decades, researchers have made impressive strides in developing methods to overcome the delivery,... Read more Molecular diagnostics Nucleic acid extraction DITCH THE SPIN COLUMNS WITHOUT COMPROMISING ON NUCLEIC ACID QUALITY Posted on Thu, Jun 29, 2023 @ 11:41 AM Whether you’re working with samples for PCR or sequencing, it's worth questioning what type of extraction or... Read more Agrigenomics WHY GENOME-EDITING CRISPR/CAS OFFERS HOPE FOR ACCELERATED SUSTAINABLE CROP IMPROVEMENT IN OIL PALM Posted on Thu, Jun 01, 2023 @ 11:09 AM Updated : Thu, June 1, 2023 @ 4:09 PM Oil palm, Elaeis guineensis Jacq., is the most productive oil crop in the world1... Read more Molecular diagnostics MASTERING ASSAY SCALE-UP: 4 TIPS TO HELP AVOID THE MOST COMMON MISTAKES Posted on Thu, May 25, 2023 @ 10:19 AM UPDATED : FRI, MAY 26, 2023 @ 10:18 AM Designing a new assay and scaling it for commercial use takes thoughtful... Read more Nucleic acid therapeutics A KNACK FOR GETTING TO THE LIVER: GALNAC ENABLES LIVER-TARGETED OLIGONUCLEOTIDE THERAPEUTICS Posted on Wed, May 24, 2023 @ 10:06 AM UPDATED : TUE, MAY 9, 2023 @ 11:03 AM When it comes to oligonucleotide therapeutics, the challenge has always been how... Read more Molecular diagnostics Oligo synthesis and modifications qPCR A WAY TO SIMPLIFY DESIGN AND INTERPRETATION OF YOUR QPCR ASSAYS Posted on Fri, May 05, 2023 @ 09:34 AM UPDATED : FRI, MAY 5, 2023 @ 2:34 PM HOW DOES A BHQ DYE CONTRIBUTE TO PRODUCING SUPERIOR DATA FROM YOUR ASSAYS? Read more Oligo synthesis and modifications Nucleic acid therapeutics WHICH CONTROLLED PORE GLASS IS RIGHT FOR YOUR THERAPEUTIC APPLICATION? Posted on Fri, Mar 31, 2023 @ 10:48 AM UPDATED : MON, JUNE 26, 2023 @ 10:24 AM Oligonucleotide therapeutics have unlocked new treatment possibilities for rare... Read more Agrigenomics PCR-based genotyping ENHANCING STRAWBERRY BREEDING WITH PREDICTIVE MODELS, MARKER-ASSISTED SELECTION AND GENOTYPING AUTOMATION Posted on Wed, Mar 08, 2023 @ 06:09 AM Updated : Tue, May 9, 2023 @ 10:48 AM Around 159,200 tonnes of strawberries are produced annually in Japan across 5,020... Read more Oligo synthesis and modifications 5-NITROINDOLE – A UNIVERSAL BASE OLIGO MODIFICATION Posted on Thu, Feb 16, 2023 @ 09:27 AM Updated : Tue, May 9, 2023 @ 10:51 AM In the next edition of the “Know your oligo mod” series, we look at a universal... Read more CELEBRATING THE WOMEN OF LGC 2023 Posted on Fri, Feb 10, 2023 @ 04:13 AM UPDATED : TUE, MAY 9, 2023 @ 10:53 AM This International Day of Women and Girls in Science (11 February) LGC Biosearch... Read more Agrigenomics PCR-based genotyping HOW MGB PROBES COULD SOLVE YOUR COMPLEX PLANT GENOME GENOTYPING ISSUES Posted on Thu, Jan 26, 2023 @ 01:34 PM UPDATED : WED, MARCH 22, 2023 @ 1:48 PM Genotyping plants can be a complex and frustrating process Read more Molecular diagnostics SARS-CoV-2 Disease detection AMP CONFERENCE 2022: DEVELOPING A 5-MINUTE POINT-OF-CARE PCR TEST Posted on Wed, Jan 11, 2023 @ 08:15 AM UPDATED : TUE, MAY 9, 2023 @ 10:57 AM We were delighted to attend the Association for Molecular Pathology (AMP) 2022... Read more Molecular diagnostics Oligo synthesis and modifications WHAT’S NEXT FOR APTAMERS IN DIAGNOSTICS? Posted on Thu, Nov 10, 2022 @ 07:25 AM UPDATED : TUE, MAY 9, 2023 @ 11:01 AM Originally developed in the early 1990s, aptamers have long been heralded as an... Read more Molecular diagnostics Nucleic acid extraction HOW TO SELECT AN EFFECTIVE NUCLEIC ACID ISOLATION METHOD FOR HUMAN DIAGNOSTICS? Posted on Tue, Oct 18, 2022 @ 10:19 AM Updated : Tue, May 9, 2023 @ 11:05 AM Molecular testing protocols for pathogen detection and diagnosing human diseases... Read more Agrigenomics PCR-based genotyping EXPLORE THE VAST APPLICATIONS OF KASP GENOTYPING FOR PLANT BREEDING PROGRAMMES Posted on Tue, Sep 20, 2022 @ 06:45 AM UPDATED : WED, MARCH 22, 2023 @ 1:22 PM Modern agriculture faces unprecedented challenges: increasing global... Read more qPCR TAQ POLYMERASE: WHAT IS IT AND ITS APPLICATIONS Posted on Fri, Aug 26, 2022 @ 07:58 AM UPDATED : WED, DECEMBER 14, 2022 @ 1:54 PM When the polymerase chain reaction (PCR) was first described, the Klenow... Read more Oligo synthesis and modifications Nucleic acid therapeutics WHERE ARE ALL THE THERAPEUTIC APTAMERS? Posted on Tue, Aug 09, 2022 @ 02:10 PM Updated : Tue, August 9, 2022 @ 7:10 PM New approaches that use aptamers as targeting agents may open the door to wider... Read more Molecular diagnostics Oligo synthesis and modifications qPCR CHOOSING THE BEST QPCR PROBE CHEMISTRY FOR YOUR ASSAY Posted on Thu, Jul 28, 2022 @ 10:15 AM UPDATED : TUE, MAY 9, 2023 @ 10:40 AM LET THE APPLICATION BE YOUR GUIDE WHEN DECIDING BETWEEN LNA, MGB AND BHQPLUS The... Read more Molecular diagnostics Disease detection PIVOTING TO MONKEYPOX DIAGNOSTICS Posted on Thu, Jul 07, 2022 @ 05:38 PM UPDATED : WED, MARCH 22, 2023 @ 1:59 PM Since 13 May 2022, reports of monkeypox cases began to appear globally in... Read more Agrigenomics PCR-based genotyping NGS-based genotyping GENETIC SOLUTIONS TO INFECTIOUS DISEASES IN AQUACULTURE Posted on Thu, Jun 30, 2022 @ 04:12 PM Updated : Mon, April 17, 2023 @ 8:33 AM This is the second blog in a two-part series exploring solutions for infectious... Read more SARS-CoV-2 Nucleic acid extraction Disease detection MAKE YOUR DIAGNOSTIC WORKFLOWS MORE ADAPTABLE Posted on Mon, Jun 06, 2022 @ 02:47 PM UPDATED : FRI, DECEMBER 16, 2022 @ 3:39 PM Since early 2020, diagnostic laboratories have had to manage patient sample... Read more Agrigenomics INCREASING RESISTANCE TO AQUACULTURE DISEASE Posted on Tue, Apr 19, 2022 @ 11:00 AM Updated : Mon, April 17, 2023 @ 1:33 PM This is the first blog in a two-part series exploring solutions for infectious... Read more SARS-CoV-2 PANDEMIC REFLECTIONS: ADAPTING TO TESTING PRIORITIES Posted on Tue, Apr 05, 2022 @ 04:55 PM UPDATED : TUE, MARCH 21, 2023 @ 3:23 PM WHAT’S CHANGED FOR CLINICAL LABS AS WE ENTER THE THIRD YEAR OF COVID-19 TESTING? Read more Molecular diagnostics qPCR OPTIMISING AUTOMATED HIGH-THROUGHPUT PATHOGEN DETECTION WORKFLOWS Posted on Wed, Mar 30, 2022 @ 11:00 AM UPDATED : WED, MARCH 30, 2022 @ 4:00 PM While both centralised and decentralised molecular diagnostics (MDx) testing... Read more Oligo synthesis and modifications Nucleic acid therapeutics OVERCOMING MANUFACTURING CHALLENGES ASSOCIATED WITH NUCLEIC ACID THERAPEUTICS Posted on Thu, Mar 24, 2022 @ 06:15 PM Updated : Tue, March 21, 2023 @ 3:46 PM This is the second blog in a two-part series exploring how oligonucleotide... Read more Agrigenomics qPCR PCR-based genotyping IMPROVING THE SUSTAINABILITY OF OIL PALM BREEDING PROGRAMMES USING MARKER-ASSISTED SELECTION Posted on Tue, Mar 08, 2022 @ 03:00 PM UPDATED : WED, MARCH 9, 2022 @ 1:05 AM African oil palm (Elaeis guineensis Jacq.) is a highly productive perennial crop... Read more Molecular diagnostics qPCR CONSIDERATIONS FOR RT-QPCR IN MOLECULAR POINT OF CARE TESTING DEVICES Posted on Tue, Mar 01, 2022 @ 03:11 PM UPDATED : FRI, APRIL 15, 2022 @ 8:58 PM The COVID-19 pandemic has accelerated the uptake of point of care testing... Read more Oligo synthesis and modifications Nucleic acid therapeutics NUCLEIC ACID THERAPEUTICS FOR NEXT-GENERATION DISEASE MANAGEMENT Posted on Fri, Feb 25, 2022 @ 02:47 PM UPDATED : TUE, MARCH 21, 2023 @ 3:44 PM This is the first blog post in a two-part series exploring how oligonucleotide... Read more qPCR SARS-CoV-2 SOCIETY CAN’T HANDLE THE CAVEATS TO EACH TYPE OF COVID-19 TEST Posted on Fri, Feb 11, 2022 @ 04:58 PM UPDATED : FRI, FEBRUARY 11, 2022 @ 10:58 PM BUT MEASUREMENT SCIENCE COULD HELP STEER US IN A BETTER, MORE INFORMED... Read more Oligo synthesis and modifications LEVERAGING QUENCHING EFFICIENCY OF BLACK HOLE QUENCHER DYES FOR PCR AND BEYOND Posted on Tue, Jan 25, 2022 @ 02:30 PM UPDATED : TUE, JANUARY 25, 2022 @ 8:30 PM MORE INNOVATIVE APPLICATIONS FOR BLACK HOLE QUENCHER (BHQ) DYES IN IMAGING... Read more RNA FISH FIVE WAYS CONTROLS CAN DEMYSTIFY YOUR STELLARIS™ RNA FISH EXPERIMENT Posted on Sun, Jan 23, 2022 @ 06:14 AM UPDATED : WED, MARCH 22, 2023 @ 1:23 PM Stellaris controls, who needs ‘em? We all do. Especially if it’s your first... Read more Agrigenomics qPCR PCR-based genotyping INCREASING HYBRID RICE BREEDING EFFICIENCY WITH HIGH-THROUGHPUT GENOTYPING Posted on Tue, Jan 18, 2022 @ 03:03 PM Updated : Thu, January 12, 2023 @ 5:10 PM Rice is the primary staple for more than half the world's population.1 With... Read more SARS-CoV-2 PANDEMIC REFLECTIONS: IN THE FACE OF SARS-COV-2 VARIANTS, COVID-19 TESTING REMAINS ESSENTIAL Posted on Tue, Jan 11, 2022 @ 12:00 PM UPDATED : TUE, JANUARY 11, 2022 @ 6:00 PM What’s changed for clinical labs as we enter the third year of COVID-19... Read more SARS-CoV-2 PANDEMIC REFLECTIONS: UNPRECEDENTED DEMAND DRIVES COVID-19 TEST DEVELOPERS TO GET CREATIVE Posted on Tue, Dec 28, 2021 @ 09:30 AM UPDATED : TUE, DECEMBER 28, 2021 @ 3:30 PM What’s changed for clinical labs as we enter the third year of COVID-19... Read more Molecular diagnostics SARS-CoV-2 TECHNICAL BULLETIN: OMICRON IMPACT ON SARS-COV-2 MUTATION ANALYSIS AND INVESTIGATION Posted on Thu, Dec 23, 2021 @ 11:45 AM Updated : Wed, March 22, 2023 @ 2:01 PM The emergence of the Omicron lineage has quickly escalated to be a variant of... Read more SARS-CoV-2 PANDEMIC REFLECTIONS: THE WORLD IS SHORT STAFFED Posted on Tue, Dec 21, 2021 @ 06:52 PM UPDATED : THU, MARCH 9, 2023 @ 5:39 PM What’s changed for clinical labs as we enter the third year of COVID-19 testing? Read more Oligo synthesis and modifications OLIGONUCLEOTIDE SYNTHESIS BASICS: KEY TAKEAWAYS FOR POST-SYNTHESIS PROCESSING Posted on Thu, Dec 16, 2021 @ 04:39 PM Updated : Wed, December 14, 2022 @ 4:45 PM This is the final blog post in a three-part educational series about best... Read more Molecular diagnostics SARS-CoV-2 ENSURING OUR DIAGNOSTIC ASSAYS DETECT THE OMICRON VARIANT Posted on Thu, Dec 09, 2021 @ 04:24 PM UPDATED : FRI, DECEMBER 10, 2021 @ 2:34 AM On 22 November 2021, The Network for Genomics Surveillance in South Africa... Read more Agrigenomics Next generation sequencing (NGS) NGS-based genotyping A TARGETED GBS TECHNOLOGY FOR ALL BREEDING COMMUNITIES Posted on Tue, Dec 07, 2021 @ 04:11 PM UPDATED : TUE, DECEMBER 7, 2021 @ 10:11 PM The decisions made by molecular breeding programmes have a substantial... Read more Molecular diagnostics EXTENSIONS TO THE IVDR - WHAT DIAGNOSTICS MANUFACTURERS AND SUPPLIERS NEED TO KNOW Posted on Thu, Dec 02, 2021 @ 05:25 PM We're excited to announce that the proposal to extend certain key provisions of the In Vitro Diagnostic Regulation... Read more Molecular diagnostics SARS-CoV-2 Disease detection STREAMLINING DIAGNOSTIC WORKFLOWS FOR COMMON RESPIRATORY DISEASES, SUCH AS SARS-COV-2, INFLUENZA AND RSV Posted on Tue, Nov 30, 2021 @ 04:29 PM UPDATED : TUE, NOVEMBER 30, 2021 @ 10:29 PM A fourth wave of COVID-19 has already emerged in many countries and a newly... Read more Agrigenomics NGS-based genotyping NGS SOLUTIONS FOR POLYPLOID PLANT BREEDING CHALLENGES Posted on Tue, Nov 23, 2021 @ 09:00 AM Updated : Fri, June 30, 2023 @ 2:19 PM Many cultivated crops with agronomic significance, including wheat, peanut, oat,... Read more Molecular diagnostics Oligo synthesis and modifications INNOVATIVE APPLICATIONS FOR BLACK HOLE QUENCHER DYES Posted on Tue, Nov 16, 2021 @ 04:14 PM UPDATED : TUE, JANUARY 25, 2022 @ 10:23 PM This is the first blog post in a two-part series highlighting how Black Hole... Read more Oligo synthesis and modifications OLIGONUCLEOTIDE SYNTHESIS BASICS: 4 KEY TAKEAWAYS FOR IN-HOUSE OLIGO PRODUCTION Posted on Tue, Nov 02, 2021 @ 11:41 AM Updated : Wed, December 14, 2022 @ 4:43 PM This is the second blog post in a three-part educational series about best... Read more Molecular diagnostics SARS-CoV-2 TECHNICAL BULLETIN: SARS-COV-2 MUTATION ANALYSIS AND INVESTIGATION Posted on Thu, Oct 14, 2021 @ 05:01 PM Updated : Thu, October 14, 2021 @ 10:01 PM SARS-CoV-2 mutations and associated new variants are being reported... Read more qPCR 8 QPCR AMPLIFICATION PLOT QUESTIONS ANSWERED Posted on Thu, Sep 30, 2021 @ 10:00 AM Updated : Thu, February 3, 2022 @ 6:10 PM When results from your qPCR assays aren’t quite what you expected, it can be... Read more Molecular diagnostics qPCR SARS-CoV-2 CAN COVID-19 TESTING BE MADE MORE SUSTAINABLE DURING PROLONGED UNCERTAINTY? Posted on Mon, Sep 27, 2021 @ 02:36 PM UPDATED : THU, MARCH 31, 2022 @ 3:24 PM In September 2021, Delta persists as the most prevalent variant worldwide1 due... Read more Molecular diagnostics THE SURPRISING GLOBAL IMPACTS OF EUROPE'S IN VITRO DIAGNOSTIC REGULATION (IVDR) Posted on Thu, Sep 16, 2021 @ 12:15 PM UPDATED : WED, SEPTEMBER 15, 2021 @ 4:40 AM A SHORTCUT TO UNDERSTANDING HOW TO PREPARE FOR IVDR In today’s global... Read more Oligo synthesis and modifications OLIGONUCLEOTIDE SYNTHESIS BASICS: INTRODUCTION TO PHOSPHORAMIDITE CHEMISTRY Posted on Tue, Sep 14, 2021 @ 02:00 PM UPDATED : WED, DECEMBER 14, 2022 @ 4:43 PM This is the first blog post in a three-part educational series about best... Read more Agrigenomics PCR-based genotyping Nucleic acid extraction 4 STEPS TO OPTIMISE SAMPLE COLLECTION FOR AQUACULTURE GENOTYPING Posted on Tue, Sep 07, 2021 @ 02:59 PM Updated : Tue, September 7, 2021 @ 7:59 PM Aquaculture breeding programmes adopt genomic technologies, including... Read more Molecular diagnostics SARS-CoV-2 TIPS FOR EARLY-STAGE MDX COMPANIES LAUNCHING NEW TESTS DURING COVID-19 TIMES Posted on Thu, Sep 02, 2021 @ 02:00 PM UPDATED : WED, NOVEMBER 9, 2022 @ 8:20 PM The COVID-19 pandemic brought tremendous change to the molecular diagnostics... Read more SARS-CoV-2 WASTEWATER SURVEILLANCE: A CRITICAL TOOL IN PANDEMIC MANAGEMENT Posted on Tue, Aug 31, 2021 @ 09:48 AM Updated : Thu, September 29, 2022 @ 7:57 PM As SARS-CoV-2 variants continue to threaten public health, officials are... Read more SARS-CoV-2 TECHNICAL BULLETIN: EMERGING SARS-COV-2 MUTATIONS AND THEIR EFFECT ON THE IMMUNE RESPONSE Posted on Wed, Aug 18, 2021 @ 03:45 PM UPDATED : THU, DECEMBER 16, 2021 @ 6:46 PM Emerging SARS-CoV-2 variants of concern and variants of interest are defined... Read more Agrigenomics Next generation sequencing (NGS) Nucleic acid extraction THE IMPORTANCE OF SAMPLE PROCESSING FOR SUCCESSFUL PLANT GENOTYPING BY NGS Posted on Thu, Aug 12, 2021 @ 06:51 PM UPDATED : THU, AUGUST 12, 2021 @ 11:51 PM Informed plant breeding decisions help drive the field of agrigenomics... Read more Agrigenomics Nucleic acid extraction DON'T UNDERESTIMATE THE COMPLEXITY OF YOUR SAMPLE COMPOSITION Posted on Wed, Aug 04, 2021 @ 04:34 PM UPDATED : WED, AUGUST 4, 2021 @ 9:34 PM A common mistake when initiating an agrigenomics project is failing to consider... Read more Agrigenomics Genomics SELECTIVE BREEDING IN AQUACULTURE: ADVANCING BREEDING PROGRAMMES THROUGH GENOMICS Posted on Wed, Jun 09, 2021 @ 11:15 AM Updated : Wed, December 14, 2022 @ 1:44 PM The global demand for fish and fish products continues to increase as... Read more Molecular diagnostics Genomics SARS-CoV-2 GENOMIC SURVEILLANCE: 3 TECHNIQUES TO DETECT AND CHARACTERISE SARS-COV-2 VARIANTS Posted on Wed, May 19, 2021 @ 11:34 AM UPDATED : THU, MARCH 9, 2023 @ 5:37 PM As the global population gains greater access to vaccines for COVID-19,... Read more Molecular diagnostics SARS-CoV-2 HOW DO SARS-COV-2 VARIANTS AFFECT PCR ASSAYS FOR COVID-19 TESTING? Posted on Tue, May 04, 2021 @ 11:03 AM UPDATED : THU, MARCH 9, 2023 @ 5:34 PM Researchers have identified several variants of SARS-CoV-2 since they sequenced... Read more Agrigenomics Genomics NGS-based genotyping BEST PRACTICES FOR IMPLEMENTING TARGETED GENOTYPING BY SEQUENCING Posted on Wed, Dec 02, 2020 @ 10:53 AM UPDATED : FRI, NOVEMBER 20, 2020 @ 5:16 PM In breeding programmes, selections based on a single or small number of... Read more Molecular diagnostics Genomics SARS-CoV-2 BUILDING RESILIENCE INTO SARS-COV-2 TESTING WORKFLOWS: CONSIDERATIONS FOR CHOOSING AN RNA ISOLATION METHOD Posted on Wed, Oct 21, 2020 @ 11:00 AM UPDATED : THU, FEBRUARY 3, 2022 @ 4:39 PM Clinical and diagnostic labs worldwide are still experiencing supply chain... Read more Genomics PCR-based genotyping HOW HIGH-THROUGHPUT GENOTYPING AUTOMATION AND KASP MARKER LIBRARIES CONNECT RESEARCH LABS WITH COMMERCIAL BREEDERS TO ACCELERATE CROP IMPROVEMENT Posted on Wed, Oct 07, 2020 @ 11:31 AM UPDATED : WED, OCTOBER 7, 2020 @ 4:33 PM “In July of 2015, I was a member of the radish genome project team. My task... Read more Agrigenomics Genomics PCR-based genotyping EMPLOYEE SPOTLIGHT: MEET DARSHNA "DUSTY" VYAS Posted on Mon, Sep 14, 2020 @ 10:15 AM UPDATED : FRI, SEPTEMBER 11, 2020 @ 9:52 PM Darshna "Dusty" Vyas has been a Senior Scientist at LGC specialising in... Read more Molecular diagnostics Genomics SARS-CoV-2 PRESSING COVID-19 TESTING ISSUES OF TODAY AND THE NEAR FUTURE Posted on Wed, Aug 26, 2020 @ 09:57 AM UPDATED : TUE, OCTOBER 6, 2020 @ 6:45 PM FOLLOWING UP WITH THE PANELISTS FROM OUR RECENT COVID-19 WEBINAR, PART 3 OF 3 ... Read more Molecular diagnostics Genomics SARS-CoV-2 SENSITIVITY AND ACCURACY IN COVID-19 TESTING Posted on Wed, Aug 19, 2020 @ 09:56 AM UPDATED : TUE, OCTOBER 6, 2020 @ 6:42 PM FOLLOWING UP WITH THE PANELISTS FROM OUR RECENT COVID-19 WEBINAR, PART 2 OF 3 ... Read more Molecular diagnostics Genomics SARS-CoV-2 SCALING UP COVID-19 VIRAL TESTING Posted on Wed, Aug 12, 2020 @ 09:47 AM UPDATED : TUE, OCTOBER 6, 2020 @ 6:45 PM FOLLOWING UP WITH THE PANELISTS FROM OUR RECENT COVID-19 WEBINAR, PART 1 OF 3 ... Read more Molecular diagnostics Genomics qPCR SARS-CoV-2 ENABLING A RAPID RESPONSE TO COVID-19 BY HONEYWELL AND LGC, BIOSEARCH TECHNOLOGIES Posted on Wed, Jul 29, 2020 @ 02:40 PM UPDATED : TUE, OCTOBER 6, 2020 @ 6:44 PM As countries worldwide begin to ease lockdown restrictions during the pandemic... Read more Agrigenomics Genomics PCR-based genotyping ESTABLISHMENT OF KASP MARKER LIBRARY FOR GENETIC DIVERSITY ANALYSIS IN BRASSICA RAPA CROPS Posted on Tue, Jul 14, 2020 @ 10:17 AM Updated : Tue, July 14, 2020 @ 1:30 PM Brassica rapa crops are important sources of food, feed, and fuel in many parts... Read more Molecular diagnostics Genomics qPCR SARS-CoV-2 ROBUST SUPPLY CHAINS AND OPEN TESTING SYSTEMS: HOW OUR AGBIO ROOTS MEET THE FDA'S EUA PROCESS TO ENABLE SOLUTIONS TO THE COVID-19 PANDEMIC Posted on Tue, May 19, 2020 @ 10:18 AM Updated : Fri, December 18, 2020 @ 8:49 PM It may seem strange that a company known for transforming the global seed... Read more Molecular diagnostics Oligo synthesis and modifications Genomics SARS-CoV-2 BEHIND THE SCENES: HOW OUR OLIGO SYNTHESIS TEAM CONTRIBUTES TO THE RELIABILITY OF YOUR ASSAYS Posted on Thu, Apr 30, 2020 @ 04:13 PM UPDATED : WED, MARCH 22, 2023 @ 1:52 PM WE’RE NOT REJECTING YOU, JUST YOUR OLIGO PCR is arguably one of the most... Read more Molecular diagnostics SARS-CoV-2 WHEN YOU DON’T NEED AN EUA FOR SARS-COV-2 TESTING Posted on Fri, Apr 10, 2020 @ 05:00 PM UPDATED : WED, NOVEMBER 25, 2020 @ 8:23 PM On March 25, 2020, the US Food and Drug Administration (FDA) held the first... Read more Genomics Next generation sequencing (NGS) NGS-based genotyping NEW NGS SERVICE LAB NOW OPEN IN MIDDLETON, WI FOR EXPANDED GLOBAL SUPPORT Posted on Wed, Apr 01, 2020 @ 11:27 AM UPDATED : WED, APRIL 1, 2020 @ 8:12 PM Back in September 2018, LGC acquired Lucigen Corporation. The ISO accredited... Read more Molecular diagnostics Oligo synthesis and modifications Genomics SARS-CoV-2 ADDRESSING COVID-19 TOGETHER: LGC, BIOSEARCH TECHNOLOGIES AND SHANGHAI LIFERIVER BIOTECHNOLOGY CO., LTD. Posted on Tue, Mar 31, 2020 @ 12:13 PM Updated : Tue, October 6, 2020 @ 6:44 PM In the nearly three months since the first confirmed case of COVID-19, the... Read more Molecular diagnostics Genomics SARS-CoV-2 WHAT DIAGNOSTIC TEST MAKERS AND CLIA LABS IN THE US NEED TO KNOW ABOUT EMERGENCY USE AUTHORIZATION (EUA) Posted on Tue, Mar 24, 2020 @ 01:58 PM Updated : Tue, March 21, 2023 @ 3:41 PM *Since the original publication of this blog, LGC Biosearch Technologies is now... Read more Molecular diagnostics Genomics SARS-CoV-2 CORONAVIRUS OUTBREAK: COLLABORATION TO MEET THE CHALLENGE Posted on Mon, Mar 16, 2020 @ 02:30 PM {% video_player "embed_player" overrideable=False, type='scriptV4', hide_playlist=True, viral_sharing=False,... Read more Molecular diagnostics Next generation sequencing (NGS) MOLECULAR DIAGNOSTICS: HOW CAN NGS LIVE UP TO ITS PROMISES? Posted on Wed, Jan 29, 2020 @ 11:37 AM UPDATED : TUE, OCTOBER 11, 2022 @ 8:43 PM The development of new genomic sequencing techniques and bioinformatics... Read more Genomics PCR-based genotyping NGS-based genotyping BACK TO BASICS - THE CRUCIAL STEP OF SAMPLE COLLECTION Posted on Wed, Jan 15, 2020 @ 11:37 AM UPDATED : MON, JANUARY 13, 2020 @ 5:08 PM BEST PRACTICE IN SAMPLE COLLECTION FOR SEQSNP TARGETED GENOTYPING BY... Read more Agrigenomics Genomics Next generation sequencing (NGS) NGS-based genotyping GENOMIC SELECTION: CAN IT ACCELERATE LIVESTOCK BREEDING? Posted on Wed, May 01, 2019 @ 10:44 AM UPDATED : WED, MAY 1, 2019 @ 3:59 PM Livestock supports the livelihoods and food security of almost 1.3 billion people... Read more Genomics THE WOMEN OF LGC, BIOSEARCH TECHNOLOGIES Posted on Fri, Mar 29, 2019 @ 11:24 AM UPDATED : FRI, MARCH 29, 2019 @ 4:39 PM We've heard it said for years, "TV will rot your brain". But in the case of our... Read more Agrigenomics PCR-based genotyping Next generation sequencing (NGS) NGS-based genotyping AGRIGENOMICS: HOW CAN NGS CONTRIBUTE TO GLOBAL FOOD SECURITY? Posted on Wed, Mar 06, 2019 @ 10:33 AM UPDATED : FRI, MAY 19, 2023 @ 8:53 AM “Experience of artificial fertilisation, such as is effected with ornamental... Read more Agrigenomics Next generation sequencing (NGS) NGS-based genotyping HOW TARGETED GBS-DRIVEN GENOMIC SELECTION CAN HELP YOU GET TO MARKET FASTER Posted on Wed, Jan 16, 2019 @ 01:22 PM UPDATED : THU, MAY 25, 2023 @ 11:32 AM Plant and animal breeding programmes often take generations to improve quality... Read more Genomics NGS-based genotyping GENOMIC SELECTION: METHODS IN CROP AND ANIMAL BREEDING Posted on Wed, Jan 09, 2019 @ 10:48 AM UPDATED : WED, JANUARY 9, 2019 @ 5:03 PM Genomic selection: 6 factors to consider when choosing between targeted GBS... Read more Agrigenomics Next generation sequencing (NGS) NGS-based genotyping OUR HUNGRY PLANET: NEW TOOLS IN AGRIGENOMICS ARE KEY TO FOOD SECURITY Posted on Tue, Dec 11, 2018 @ 10:32 AM UPDATED : TUE, DECEMBER 11, 2018 @ 4:32 PM Food security is a major global threat and traditional methods of plant and... Read more PCR-based genotyping ACCELERATING RICE IMPROVEMENT IN SOUTH ASIA Posted on Thu, Jul 26, 2018 @ 11:26 AM Updated : Thu, July 26, 2018 @ 4:41 PM Diversity is the spice of life and is also key to breeding rice that delivers... Read more Genomics REVOLUTIONISING CANCER TREATMENT ONE ARRAY AT A TIME Posted on Tue, Jul 10, 2018 @ 11:05 AM UPDATED : MON, SEPTEMBER 19, 2022 @ 2:14 PM While the science of pharmacogenomics has been around for years, its... Read more Genomics Nucleic acid extraction PACK IT UP, PACK IT IN, LET ME BEGIN: A LOOK AT THE FUTURE OF DNA DATA STORAGE Posted on Thu, Jun 28, 2018 @ 11:13 AM UPDATED : THU, JUNE 28, 2018 @ 4:28 PM Imagine a time capsule the size of a shoebox that holds all the information... Read more RNA FISH Genomics WARNING! PITFALLS AHEAD: HOW TO AVOID THE MOST COMMON STELLARIS RNA FISH MISTAKES Posted on Tue, May 29, 2018 @ 10:32 AM UPDATED : TUE, MAY 29, 2018 @ 3:47 PM Ever wake up in the morning just feeling like a rock star, or maybe like Francis... Read more RNA FISH Genomics SHINING A LIGHT ON GENE EXPRESSION AND REGULATION ONE CELL AT A TIME Posted on Thu, Apr 19, 2018 @ 12:51 PM UPDATED : MON, APRIL 30, 2018 @ 1:53 PM To truly understand complex diseases such as cancer, scientists need access to... Read more Genomics THE WOMEN OF LGC Posted on Thu, Mar 29, 2018 @ 10:45 AM UPDATED : THU, MARCH 29, 2018 @ 4:00 PM Ask any little girl what they want to be when they grow up and you may hear... Read more RNA FISH Genomics IN CASE YOU MISSED IT: STELLARIS RNA FISH LUNCH-AND-LEARN Posted on Tue, Jan 16, 2018 @ 10:35 AM UPDATED : TUE, JANUARY 16, 2018 @ 4:50 PM Stellaris® RNA FISH (fluorescence in situ hybridization) is an RNA... Read more Agrigenomics Genomics NGS-based genotyping TACKLING FOOD CRISIS THROUGH COST EFFECTIVE, TARGET ENRICHED SEQUENCING Posted on Wed, Dec 13, 2017 @ 10:07 AM UPDATED : MON, SEPTEMBER 19, 2022 @ 2:16 PM With the global population predicted to reach 9 billion people within the... Read more Agrigenomics Genomics PCR-based genotyping NEW SNPS IDENTIFIED IN THE HUNT FOR NEW GENETIC WEAPONS TARGETING LEAF RUST IN WHEAT Posted on Tue, Nov 21, 2017 @ 11:25 AM UPDATED : WED, NOVEMBER 22, 2017 @ 1:44 PM Wheat is one of the three most important crops for human and livestock feed.... Read more Agrigenomics Genomics PCR-based genotyping SUPER-CROPS HELPING TO FEED AFRICA Posted on Fri, Nov 03, 2017 @ 11:08 AM UPDATED : TUE, JULY 10, 2018 @ 9:08 PM Our world population is growing at a tremendous rate and by 2050, Africa’s... Read more Genomics PCR-based genotyping Disease detection HOW GENOTYPING IS AIDING IN THE FIGHT AGAINST MALARIA Posted on Wed, Sep 20, 2017 @ 10:11 AM Updated : Mon, September 19, 2022 @ 2:14 PM 3.2 billion people across 106 countries and territories, live in areas at... Read more RNA FISH Genomics LUNCH & LEARN: STELLARIS RNA FISH Posted on Thu, Jul 06, 2017 @ 10:07 AM UPDATED : THU, JULY 6, 2017 @ 3:22 PM Recently LGC Genomics hosted a lunch and learn Stellaris® seminar at the Helen... Read more Genomics qPCR IT’S OFFICIAL! PERSONAL HEALTH BECOMES FIRST CHINA DEMONSTRATION LABORATORY SITE FOR LGC’S NEXAR SYSTEM Posted on Wed, May 03, 2017 @ 09:05 AM Updated : Mon, September 19, 2022 @ 2:07 PM LGC's Genomics Division has signed a memorandum of understanding (MOU) with... Read more qPCR DIGITAL PCR – IMPROVING REPRODUCIBLE MOLECULAR METHODS IN THE CLINIC Posted on Thu, Apr 06, 2017 @ 10:40 AM UPDATED : THU, APRIL 6, 2017 @ 3:40 PM A recent study coordinated by LGC and published in the journal Analytical... Read more RNA FISH Disease detection SHINING A LIGHT ON HOW ZIKA VIRUS MAY SPREAD FROM MOTHERS TO HUMAN FETUSES Posted on Mon, Mar 06, 2017 @ 10:37 AM UPDATED : MON, MARCH 6, 2017 @ 4:37 PM New research has, for the first time, found evidence suggesting the molecular... Read more WATER – BACK TO BASICS FOR THERMAL CYCLING Posted on Tue, Feb 28, 2017 @ 10:13 AM UPDATED : MON, SEPTEMBER 19, 2022 @ 2:20 PM It’s time to forget what you know about heating your PCR plates for... Read more Genomics PCR-based genotyping OVERCOMING DROUGHT-INTOLERANCE IN MAIZE TO FEED THE GROWING ASIAN POPULATION Posted on Wed, Feb 15, 2017 @ 09:53 AM UPDATED : WED, FEBRUARY 15, 2017 @ 4:23 PM Demand for maize is increasing due to an increased number of people... Read more Genomics AUTOMATE TO ACCELERATE AND SCALE-UP SNP-BASED GENOTYPING WORKFLOWS! Posted on Thu, Feb 02, 2017 @ 09:14 AM UPDATED : MON, SEPTEMBER 19, 2022 @ 2:05 PM The advent of and ongoing improvements to next-generation sequencing... Read more Genomics MULTIPLE MISUNDERSTANDINGS: LEARNING FROM GENETIC DETERMINISM Posted on Mon, Jan 23, 2017 @ 10:12 AM UPDATED : MON, JANUARY 23, 2017 @ 4:27 PM Nature versus nurture. It’s a tale as old as time. When Craig Venter made the... Read more Agrigenomics Genomics PCR-based genotyping NGS-based genotyping HELPING TO FEED THE WORLD WITH GENOTYPING BY SEQUENCING Posted on Tue, Jan 17, 2017 @ 09:42 PM UPDATED : WED, JANUARY 18, 2017 @ 2:13 PM Many areas critical to improved agricultural production require robust and... Read more PCR-based genotyping FASTER, STRONGER, QUICKER: SSR TO KASP WILL GET YOU THERE Posted on Mon, Jan 09, 2017 @ 09:05 AM UPDATED : MON, JANUARY 9, 2017 @ 3:20 PM Screen more markers faster and bring crops with superior traits to the market... Read more Genomics qPCR MULTIPLEX YOUR QPCR AND WALK-AWAY Posted on Thu, Dec 15, 2016 @ 10:17 AM UPDATED : MON, SEPTEMBER 19, 2022 @ 2:15 PM It seems everyone wants to do more with less, and automate the process as... Read more RNA FISH Genomics A STELLAR-IS YEAR IN THE MAKING Posted on Wed, Dec 07, 2016 @ 10:05 AM UPDATED : MON, SEPTEMBER 19, 2022 @ 2:12 PM It wouldn't be fair to close out 2016 without showcasing the stellar year... Read more Genomics BUDDY UP: THE DOUBLE HELIX Posted on Mon, Nov 28, 2016 @ 09:15 AM UPDATED : MON, NOVEMBER 28, 2016 @ 11:31 PM The secret of life. That’s what Francis Crick and James Watson claimed they... Read more Genomics GENES, PROTEINS & DNA: OUR HEREDITARY SOFTWARE Posted on Mon, Nov 21, 2016 @ 09:17 AM UPDATED : MON, NOVEMBER 21, 2016 @ 3:32 PM In the early 1900s, scientists found that the function of genes was to make... Read more Genomics "X" MARKS THE SPOT: A CLOSER LOOK AT CHROMOSOMES Posted on Mon, Nov 14, 2016 @ 09:28 AM UPDATED : WED, MARCH 29, 2023 @ 10:51 AM The strands of DNA in your cells are organized into pieces called chromosomes.... Read more Genomics EXCEL AUTOCORRECT FAILS THE GENOMICS COMMUNITY - ARE YOUR RESULTS EXCELLENT OR EXCEL-NOT? Posted on Thu, Sep 08, 2016 @ 11:30 AM UPDATED : MON, SEPTEMBER 19, 2022 @ 2:13 PM Researchers from the Baker IDI Heart and Diabetes Institute in Melbourne,... Read more qPCR QPCR-BASED MOLECULAR DIAGNOSTICS AT THE FOREFRONT OF ZIKA SURVEILLANCE Posted on Tue, Aug 23, 2016 @ 04:00 PM UPDATED : WED, MARCH 29, 2023 @ 11:04 AM As the Zika virus outbreak spreads, a wave of international concern has grown,... Read more Oligo synthesis and modifications KNOW YOUR OLIGO MOD: THIO C6 LINKER Posted on Thu, Jul 14, 2016 @ 04:00 PM UPDATED : WED, MARCH 29, 2023 @ 10:55 AM THIO C6 LINKER (THIOHEXYL) We continue our “Know Your Oligo Mod” series with... Read more Agrigenomics A COMPLETE ECOSYSTEM TO ACCELERATE BREEDING PROGRAMS [INFOGRAPHIC] Posted on Tue, Jun 28, 2016 @ 04:00 PM UPDATED : TUE, JUNE 28, 2016 @ 9:00 PM Modern breeding methods rely on the identification and utilization of molecular... Read more Molecular diagnostics Oligo synthesis and modifications qPCR PHOTOBLOG: BEHIND THE SCENES OF OLIGO SYNTHESIS Posted on Wed, May 18, 2016 @ 05:00 PM UPDATED : WED, DECEMBER 14, 2022 @ 5:04 PM OLIGO SYNTHESIS PHOTO GLIMPSE We’ve recently captured our talented... Read more qPCR NOVA IS THE NEW BLACK Posted on Thu, Apr 14, 2016 @ 04:00 PM Updated : Mon, April 24, 2023 @ 8:54 AM LGC Biosearch Technologies has developed a new qPCR probe format powered by... Read more LEARN ABOUT THE LATEST DEVELOPMENTS IN TECHNOLOGIES FOR MOLECULAR BREEDING PROGRAMS Posted on Thu, Mar 31, 2016 @ 04:00 PM UPDATED : THU, MARCH 31, 2016 @ 9:01 PM At this year’s 24th annual Plant & Animal Genome (PAG) conference, LGC... Read more RNA FISH IMAGING STELLARIS ASSAYS PART III: CREATING PROFESSIONAL, PUBLICATION-READY IMAGES Posted on Thu, Mar 10, 2016 @ 04:00 PM Updated : Wed, August 16, 2017 @ 9:15 AM Here is the final installment of our “Imaging Stellaris Assays” blog series.... Read more RNA FISH DESIGNING STELLARIS RNA FISH PROBES PART I: INCREASING PROBE COUNT Posted on Thu, Jan 14, 2016 @ 04:00 PM Updated : Tue, September 27, 2022 @ 2:32 PM Stellaris® RNA FISH is a novel technology that allows for the detection of... Read more Oligo synthesis and modifications qPCR KNOW YOUR OLIGO MOD: 3' SPACER C3 Posted on Thu, Oct 15, 2015 @ 04:15 PM UPDATED : WED, MARCH 29, 2023 @ 10:54 AM This week, we continue our Know your oligo mod blog series and we will focus... Read more RNA FISH IMAGING STELLARIS ASSAYS PART II: HOW TO ACQUIRE STUNNING IMAGES Posted on Thu, Sep 24, 2015 @ 04:30 PM UPDATED : WED, AUGUST 16, 2017 @ 9:13 AM Here we continue our “Imaging Stellaris Assays” blog series. We last left off... Read more RNA FISH RUNAWAY RNA STAYS PUT Posted on Thu, Sep 17, 2015 @ 04:00 PM UPDATED : TUE, MARCH 21, 2023 @ 3:53 PM The cleavage and polyadenylation event, the final trimming in the molecular... Read more RNA FISH IMAGING STELLARIS ASSAYS PART I: GET TO KNOW YOUR MICROSCOPE Posted on Thu, Aug 27, 2015 @ 07:00 PM UPDATED : WED, AUGUST 16, 2017 @ 9:42 PM Stellaris® FISH is an RNA detection technology performed by means of in situ... Read more Oligo synthesis and modifications THE AGCT’S OF DNA SYNTHESIS Posted on Tue, Aug 11, 2015 @ 04:00 PM UPDATED : WED, MARCH 29, 2023 @ 10:38 AM Chemically synthesized DNA has become an indispensable tool for molecular... Read more Oligo synthesis and modifications KNOW YOUR OLIGO MOD: BHQ® (BLACK HOLE QUENCHER®) NON-FLUORESCENT QUENCHERS Posted on Thu, Jul 23, 2015 @ 04:00 PM UPDATED : FRI, JANUARY 13, 2023 @ 11:35 AM In this instalment, we will cover the basics of LGC Biosearch Technologies’... Read more RNA FISH qPCR AND THE CONSENSUS (SEQUENCE) IS... Posted on Thu, Jun 11, 2015 @ 04:31 PM UPDATED : FRI, NOVEMBER 13, 2015 @ 9:25 PM Studying the expression level of RNA transcripts is often complicated by the... Read more RNA FISH RESEARCH HIGHLIGHT: BRINGING VISION RESEARCH INTO FOCUS Posted on Thu, May 28, 2015 @ 04:14 PM UPDATED : TUE, MARCH 21, 2023 @ 3:37 PM Gene expression and molecular biology research in vision and ophthalmology... Read more RNA FISH FISH-ING FOR FUSIONS: A UNIQUE APPROACH TO FUSION GENE MRNA & PRE-MRNA DETECTION IN CANCER Posted on Fri, May 15, 2015 @ 03:00 PM UPDATED : FRI, NOVEMBER 13, 2015 @ 10:27 PM This past April, Biosearch attended the American Association of Cancer... Read more qPCR HOW MUCH IS YOUR QPCR ASSAY REALLY COSTING YOU? Posted on Thu, Apr 02, 2015 @ 04:00 PM UPDATED : FRI, NOVEMBER 13, 2015 @ 10:40 PM In the setup of a qPCR experiment, one of the first decisions to make is... Read more RNA FISH THE 4CS OF STELLARIS® RNA FISH BUFFERS Posted on Thu, Feb 26, 2015 @ 04:00 PM UPDATED : MON, NOVEMBER 16, 2015 @ 3:55 PM Buffers are often overlooked and taken for granted until the day comes when... Read more Oligo synthesis and modifications KNOW YOUR OLIGO MOD: PHOSPHOROTHIOATE BONDS Posted on Thu, Feb 12, 2015 @ 04:00 PM UPDATED : WED, MARCH 29, 2023 @ 10:56 AM This post in our continuing series, “Know your oligo mod” will cover ... Read more qPCR OPTIMISING MULTIPLEX COMPETITIVE QRT-PCR IN DIAGNOSTICS WITH BHQPLUS PROBES Posted on Thu, Jan 29, 2015 @ 04:00 PM UPDATED : MON, NOVEMBER 16, 2015 @ 5:30 PM In a webinar linked below, Dr. James Willey describes a two colour... Read more qPCR PCR-based genotyping A SUCCESSFUL DUO FOR ACCURATE, SPEEDY, AND ECONOMICAL SNP GENOTYPING Posted on Thu, Jan 08, 2015 @ 01:30 PM UPDATED : MON, SEPTEMBER 19, 2022 @ 2:12 PM Single Nucleotide Polymorphisms (SNPs) have been widely studied for over 15... Read more Oligo synthesis and modifications KNOW YOUR OLIGO MOD: METHYLENE BLUE Posted on Tue, Dec 09, 2014 @ 04:02 PM UPDATED : WED, MARCH 29, 2023 @ 10:56 AM The chemical synthesis of oligonucleotides allows for the incorporation of a... Read more RNA FISH UNRAVELING THE NEURAL WEB: STELLARIS® RNA FISH FOR NEUROSCIENCE RESEARCH Posted on Thu, Nov 13, 2014 @ 05:45 PM UPDATED : MON, SEPTEMBER 19, 2022 @ 2:14 PM Neuroscience gene expression research can come with many hurdles,... Read more qPCR CHECK OUT OUR NEW WEBSITE QPCR DESIGN LAB @ QPCRDESIGN.COM Posted on Thu, Oct 23, 2014 @ 04:00 PM UPDATED : TUE, MARCH 28, 2023 @ 9:02 PM Biosearch Technologies has launched qPCRdesign.com, a microsite targeted... Read more Oligo synthesis and modifications qPCR DELIVERING OLIGOS BY NANOMOLE UNITS Posted on Wed, Oct 15, 2014 @ 01:00 PM UPDATED : TUE, OCTOBER 14, 2014 @ 10:21 PM Different oligonucleotide manufacturers deliver probes and primers in a... Read more Molecular diagnostics qPCR RT-QPCR MOLECULAR DIAGNOSTICS ASSIST WORKERS AT THE FOREFRONT OF EBOLA OUTBREAK. Posted on Thu, Sep 25, 2014 @ 01:30 PM UPDATED : MON, SEPTEMBER 19, 2022 @ 2:13 PM The largest recorded Ebola Virus Disease outbreak in history continues to... Read more qPCR ONE STEP TOO MANY? SIMPLIFY YOUR QPCR PROTOCOL Posted on Thu, Feb 27, 2014 @ 12:02 PM UPDATED : MON, SEPTEMBER 19, 2022 @ 2:12 PM Don’t waste time performing an extra step. Cut back on pipetting and order... Read more qPCR 30 YEARS: THE IMPACT OF PCR Posted on Thu, Sep 05, 2013 @ 11:29 AM UPDATED : TUE, MARCH 21, 2023 @ 3:52 PM Do you remember when the most popular method of DNA amplification involved... Read more RNA FISH qPCR RT-QPCR AND THE STELLARIS FISH METHOD Posted on Fri, Apr 26, 2013 @ 12:32 PM UPDATED : MON, SEPTEMBER 19, 2022 @ 2:10 PM A "Referral from the Doctor" Blog Article- Quantitative reverse... Read more BIOSEARCH TECHNOLOGIES RESPONDS TO CHINA INFLUENZA H7N9 OUTBREAK BY PROVIDING H7N9 DETECTION PANEL Posted on Mon, Apr 15, 2013 @ 08:00 AM UPDATED : MON, SEPTEMBER 19, 2022 @ 2:13 PM Biosearch Technologies, Inc. (Biosearch) announced today that the company... Read more RNA FISH STELLARIS® FOUNDATION GENES: GAPDH Posted on Thu, Apr 11, 2013 @ 11:30 AM UPDATED : WED, OCTOBER 1, 2014 @ 4:53 PM Stellaris probe sets targeting glyceraldehyde-3-phosphate dehydrogenase... Read more RNA FISH BIOSEARCH TECHNOLOGIES, UMDNJ STELLARIS® PROBE ALLIANCE - NEXTGEN GENE EXPRESSION™, SNP FISH™, AND ICEFISH™ IN RESEARCH AND CLINICAL APPLICATIONS Posted on Mon, Mar 18, 2013 @ 10:43 AM UPDATED : MON, SEPTEMBER 19, 2022 @ 2:07 PM Biosearch Technologies, Inc. (Biosearch), a leading supplier of... Read more BIOSEARCH TECHNOLOGIES ANNOUNCES ACQUISITION OF EUROPEAN COMPANIES DNA TECHNOLOGY AND VITRABIO Posted on Thu, Feb 21, 2013 @ 08:00 AM UPDATED : WED, OCTOBER 1, 2014 @ 4:53 PM Biosearch Technologies, Inc. (Biosearch), a leading supplier of... Read more RNA FISH BIOSEARCH TECHNOLOGIES LAUNCHES CATALOGUED STELLARIS™ RNA FISH ASSAYS Posted on Mon, Jun 18, 2012 @ 10:08 AM UPDATED : MON, SEPTEMBER 19, 2022 @ 2:07 PM Biosearch Technologies, Inc. (Biosearch), a leading supplier of... Read more RNA FISH SINGLE MOLECULE VIRAL RNA ANALYSIS USING STELLARIS™ FISH TECHNOLOGY Posted on Wed, May 30, 2012 @ 03:00 PM IMAGE COURTESY OF: HTTP://WWW.CDC.GOV/H1N1FLU/IMAGES.HTM UPDATED : MON, SEPTEMBER 19, 2022 @ 2:13 PM A... Read more Molecular diagnostics qPCR QPCR PROBES AT WORK: INNOVATIVE CLIA TEST FOR NSCLC STAGING Posted on Tue, Mar 06, 2012 @ 01:00 PM UPDATED : WED, OCTOBER 1, 2014 @ 4:51 PM Non-squamous, Non-small cell lung cancer (NSCLC), the most common cause of... Read more qPCR FACTORS AFFECTING FLUOROPHORE PERFORMANCE IN QPCR Posted on Wed, Jan 11, 2012 @ 11:00 AM UPDATED : FRI, OCTOBER 21, 2022 @ 10:24 AM Fluorophores are molecules that can absorb light energy in a process called... Read more THE 'MONTE CARLO' EFFECT IN QPCR Posted on Wed, Nov 09, 2011 @ 01:00 PM UPDATED : MON, SEPTEMBER 19, 2022 @ 2:10 PM A "Referral from the Doctor" Blog Article- The mathematical model of PCR... Read more qPCR FLUORESCENCE QUENCHING MECHANISMS FOR DUAL-LABELED PROBES Posted on Wed, Jun 29, 2011 @ 09:44 AM UPDATED : MON, SEPTEMBER 19, 2022 @ 2:10 PM A "Referral from the Doctor" Blog Article- Fluorescent probes are used in... Read more qPCR MULTIPLEXING WITH XANTHENES Posted on Wed, Jun 08, 2011 @ 11:13 AM UPDATED : MON, SEPTEMBER 19, 2022 @ 2:10 PM A "Referral from the Doctor" Blog Article- Quantitative real-time PCR... Read more qPCR QPCR TROUBLESHOOTING: INTERPRETING AMPLIFICATION CURVES AND DIAGNOSING PROBLEMS Posted on Thu, May 05, 2011 @ 12:15 PM UPDATED : THU, MAY 11, 2023 @ 10:06 AM If you run quantitative real-time PCR (qPCR) assays, the chances are that... Read more qPCR BETWEEN ROX AND A HARD PLACE Posted on Wed, Nov 10, 2010 @ 11:12 AM UPDATED : MON, SEPTEMBER 19, 2022 @ 2:10 PM A "Referral from the Doctor" Blog Article- ROX in qPCR Quantitative... Read more Molecular diagnostics VISIT BIOSEARCH AT IVD TECHNOLOGY'S VIRTUAL CONFERENCE AND TRADESHOW Posted on Thu, Sep 23, 2010 @ 04:32 PM UPDATED : MON, SEPTEMBER 19, 2022 @ 2:07 PM Biosearch Technologies is proud to sponsor the first IVD Technology... Read more Molecular diagnostics PILOTDX OLIGOS: EN ROUTE TO IVD Posted on Thu, Jul 22, 2010 @ 10:07 AM UPDATED : WED, OCTOBER 1, 2014 @ 4:42 PM It can be difficult to transition a product from research to... Read more qPCR PIPETTING FOR QPCR Posted on Wed, Jun 09, 2010 @ 10:41 AM UPDATED : MON, SEPTEMBER 19, 2022 @ 2:14 PM A "Referral from the Doctor" Blog Article- Research trends in laboratories... Read more qPCR KILLER PROBES FOR QPCR: WHAT IS A SCORPIONS PRIMER? Posted on Wed, Mar 24, 2010 @ 10:57 AM UPDATED : THU, MARCH 23, 2023 @ 11:57 AM Scorpions™ Primers are dual-labeled FRET probes that combine a Molecular... Read more qPCR A LIGHT IN THE STORM: WHAT IS A MOLECULAR BEACON? Posted on Wed, Mar 10, 2010 @ 12:00 PM UPDATED : MON, MARCH 20, 2023 @ 9:54 PM Molecular Beacons are a special type of dual-labeled oligonucleotide probe.... Read more qPCR DUAL-LABELED BHQ PROBES - PERFORMANCE TO “DYE” FOR Posted on Wed, Feb 24, 2010 @ 12:20 PM UPDATED : MON, SEPTEMBER 19, 2022 @ 2:10 PM A "Referral from the Doctor" Blog Article A BHQ® probe is a dual-labeled... Read more qPCR THIS YEAR'S MVP (MOST VALUABLE PRACTICE): TOUCHDOWN PCR Posted on Thu, Feb 04, 2010 @ 12:39 PM UPDATED : MON, SEPTEMBER 19, 2022 @ 2:10 PM A "Referral from the Doctor" Blog Article- The aim of the Polymerase... Read more qPCR THE GRAND BALLET: WINE AND BIOTECHNOLOGY Posted on Wed, Jan 27, 2010 @ 01:15 PM UPDATED : WED, OCTOBER 1, 2014 @ 4:38 PM At the third qPCR Symposium, held November 9th -12th in Millbrae, CA, ETS... Read more qPCR ALTERNATIVE TO DNASE I HEAT INACTIVATION Posted on Wed, Jan 13, 2010 @ 12:04 PM UPDATED : WED, DECEMBER 14, 2022 @ 4:20 PM A "Referral from the Doctor" Blog Article- Genomic DNA contamination has... Read more qPCR A QUICK JUMP START TO MULTIPLEXING QPCR Posted on Wed, Jan 06, 2010 @ 12:01 PM UPDATED : THU, SEPTEMBER 22, 2022 @ 5:16 PM By now, you've no doubt read about the reductions in error, cost and time... Read more qPCR SLOPE EFFICIENCY EQUALS MANAGEABLE AND CORRECTED PCR Posted on Wed, Dec 09, 2009 @ 02:01 PM UPDATED : MON, SEPTEMBER 19, 2022 @ 2:10 PM A "Referral from the Doctor" Blog Article- ε = m.c.2 (shall I explain?... Read more qPCR BRINGING BACK A CHAMPION: COMPETITIVE QUANTITATIVE REAL-TIME RT-PCR Posted on Wed, Nov 18, 2009 @ 10:08 AM UPDATED : MON, SEPTEMBER 19, 2022 @ 2:10 PM A "Referral from the Doctor" Blog Article- Competitive qRT-PCR has become... Read more Oligo synthesis and modifications qPCR THE NEW FAVORITE REFERENCE GENE: 36B4, A.K.A. RPLP0 Posted on Wed, Oct 14, 2009 @ 10:06 AM UPDATED : MON, SEPTEMBER 19, 2022 @ 2:10 PM A "Referral from the Doctor" Blog Article- Ribosomes are comprised of two... Read more qPCR WHAT GENES ARE HOT, WHAT GENES ARE NOT Posted on Wed, Oct 07, 2009 @ 04:41 PM UPDATED : MON, SEPTEMBER 19, 2022 @ 2:10 PM A "Referral from the Doctor" Blog Article- Top 10 Reference Genes for... Read more Oligo synthesis and modifications qPCR LABELING OLIGONUCLEOTIDES WITH INTERNAL BHQ DYES Posted on Tue, Sep 29, 2009 @ 10:16 AM UPDATED : FRI, JANUARY 13, 2023 @ 11:38 AM WHEN TO USE AN INTERNAL BLACK HOLE QUENCHER (BHQ) LABEL IN A... Read more Oligo synthesis and modifications qPCR SALT-FREE PRIMER PAIR OPTION NOW AVAILABLE Posted on Tue, Sep 22, 2009 @ 10:08 AM UPDATED : MON, SEPTEMBER 19, 2022 @ 2:12 PM Biosearch Technologies will now be offering the option of salt-free... Read more Disease detection Nucleic acid therapeutics WHY CIRCULAR RNA COULD BE THE NEXT REVOLUTION IN RNA THERAPEUTICS While RNA-based therapeutics are taking the biotechnology world by storm following the rapid development of the COVID-19 vaccines, the next generation of... Read more Oligo synthesis and modifications Nucleic acid therapeutics SYNTHESIZING YOUR OWN OLIGONUCLEOTIDES: FAQS Considering bringing oligo synthesis in-house? Here are some commonly asked questions that we receive, grouped into four sections. You can jump to a section... Read more Molecular diagnostics HOW TO DESIGN MRNA THERAPEUTICS FOR SCALABLE SUCCESS The recent Nobel Prize awarded to Katalin Karikó and Drew Weissman underlined the impact their breakthroughs in mRNA technology had in combating COVID-19.... Read more Molecular diagnostics Disease detection THE RISE OF LAMP FOR RAPID POINT-OF-NEED TESTING As the world scrambled to rapidly expand PCR testing capacity in 2020, it became increasingly clear that there was a need for cheaper, simpler, quicker... Read more Molecular diagnostics qPCR MINIMISING ANTIBIOTIC DEPENDENCY FOR TREATING UTIS AND STIS Antimicrobial resistance (AMR) across bacterial species is developing rapidly, compounded by the improper use of antimicrobial agents that accelerates the... Read more Oligo synthesis and modifications Nucleic acid therapeutics WHAT’S THE LATEST IN ASO AND SIRNA TECHNOLOGIES? Over the last few decades, researchers have made impressive strides in developing methods to overcome the delivery, stability, and specificity challenges of... Read more Molecular diagnostics Nucleic acid extraction DITCH THE SPIN COLUMNS WITHOUT COMPROMISING ON NUCLEIC ACID QUALITY Whether you’re working with samples for PCR or sequencing, it's worth questioning what type of extraction or purification method would work well with your... Read more Molecular diagnostics MASTERING ASSAY SCALE-UP: 4 TIPS TO HELP AVOID THE MOST COMMON MISTAKES UPDATED : FRI, MAY 26, 2023 @ 10:18 AM Designing a new assay and scaling it for commercial use takes thoughtful planning, foresight, and engagement with... Read more Nucleic acid therapeutics A KNACK FOR GETTING TO THE LIVER: GALNAC ENABLES LIVER-TARGETED OLIGONUCLEOTIDE THERAPEUTICS UPDATED : TUE, MAY 9, 2023 @ 11:03 AM When it comes to oligonucleotide therapeutics, the challenge has always been how to deliver an intact oligo to the right... Read more Molecular diagnostics Oligo synthesis and modifications qPCR General science A WAY TO SIMPLIFY DESIGN AND INTERPRETATION OF YOUR QPCR ASSAYS UPDATED : FRI, MAY 5, 2023 @ 2:34 PM HOW DOES A BHQ DYE CONTRIBUTE TO PRODUCING SUPERIOR DATA FROM YOUR ASSAYS? Read more Oligo synthesis and modifications Nucleic acid therapeutics WHICH CONTROLLED PORE GLASS IS RIGHT FOR YOUR THERAPEUTIC APPLICATION? UPDATED : MON, JUNE 26, 2023 @ 10:24 AM Oligonucleotide therapeutics have unlocked new treatment possibilities for rare and fatal diseases often associated... Read more Molecular diagnostics SARS-CoV-2 Disease detection AMP CONFERENCE 2022: DEVELOPING A 5-MINUTE POINT-OF-CARE PCR TEST UPDATED : TUE, MAY 9, 2023 @ 10:57 AM We were delighted to attend the Association for Molecular Pathology (AMP) 2022 annual meeting, held in Phoenix, Arizona... Read more Molecular diagnostics Oligo synthesis and modifications WHAT’S NEXT FOR APTAMERS IN DIAGNOSTICS? UPDATED : TUE, MAY 9, 2023 @ 11:01 AM Originally developed in the early 1990s, aptamers have long been heralded as an antibody alternative for detection... Read more Molecular diagnostics Nucleic acid extraction General science HOW TO SELECT AN EFFECTIVE NUCLEIC ACID ISOLATION METHOD FOR HUMAN DIAGNOSTICS? Updated : Tue, May 9, 2023 @ 11:05 AM Molecular testing protocols for pathogen detection and diagnosing human diseases require reliable and high-quality... Read more Oligo synthesis and modifications Nucleic acid therapeutics General science WHERE ARE ALL THE THERAPEUTIC APTAMERS? Updated : Tue, August 9, 2022 @ 7:10 PM New approaches that use aptamers as targeting agents may open the door to wider clinical use in the future Read more Molecular diagnostics Oligo synthesis and modifications qPCR General science CHOOSING THE BEST QPCR PROBE CHEMISTRY FOR YOUR ASSAY UPDATED : TUE, MAY 9, 2023 @ 10:40 AM LET THE APPLICATION BE YOUR GUIDE WHEN DECIDING BETWEEN LNA, MGB AND BHQPLUS The many different chemistries available... Read more Molecular diagnostics Disease detection PIVOTING TO MONKEYPOX DIAGNOSTICS UPDATED : WED, MARCH 22, 2023 @ 1:59 PM Since 13 May 2022, reports of monkeypox cases began to appear globally in regions not endemic to the monkeypox virus.1... Read more SARS-CoV-2 Nucleic acid extraction Disease detection General science MAKE YOUR DIAGNOSTIC WORKFLOWS MORE ADAPTABLE UPDATED : FRI, DECEMBER 16, 2022 @ 3:39 PM Since early 2020, diagnostic laboratories have had to manage patient sample quantities being in a state of flux.... Read more SARS-CoV-2 PANDEMIC REFLECTIONS: ADAPTING TO TESTING PRIORITIES UPDATED : TUE, MARCH 21, 2023 @ 3:23 PM WHAT’S CHANGED FOR CLINICAL LABS AS WE ENTER THE THIRD YEAR OF COVID-19 TESTING? COVID-19, the illness caused by... Read more Molecular diagnostics qPCR General science OPTIMISING AUTOMATED HIGH-THROUGHPUT PATHOGEN DETECTION WORKFLOWS UPDATED : WED, MARCH 30, 2022 @ 4:00 PM While both centralised and decentralised molecular diagnostics (MDx) testing models play an important role in patient... Read more Oligo synthesis and modifications Nucleic acid therapeutics OVERCOMING MANUFACTURING CHALLENGES ASSOCIATED WITH NUCLEIC ACID THERAPEUTICS Updated : Tue, March 21, 2023 @ 3:46 PM This is the second blog in a two-part series exploring how oligonucleotide modifications can support the advancement of... Read more Molecular diagnostics qPCR General science CONSIDERATIONS FOR RT-QPCR IN MOLECULAR POINT OF CARE TESTING DEVICES UPDATED : FRI, APRIL 15, 2022 @ 8:58 PM The COVID-19 pandemic has accelerated the uptake of point of care testing (POCT), with simple, user-administered tests... Read more Oligo synthesis and modifications Nucleic acid therapeutics NUCLEIC ACID THERAPEUTICS FOR NEXT-GENERATION DISEASE MANAGEMENT UPDATED : TUE, MARCH 21, 2023 @ 3:44 PM This is the first blog post in a two-part series exploring how oligonucleotide modifications can support the... Read more qPCR SARS-CoV-2 General science SOCIETY CAN’T HANDLE THE CAVEATS TO EACH TYPE OF COVID-19 TEST UPDATED : FRI, FEBRUARY 11, 2022 @ 10:58 PM BUT MEASUREMENT SCIENCE COULD HELP STEER US IN A BETTER, MORE INFORMED DIRECTION COVID-19 tests can indicate the... Read more SARS-CoV-2 PANDEMIC REFLECTIONS: IN THE FACE OF SARS-COV-2 VARIANTS, COVID-19 TESTING REMAINS ESSENTIAL UPDATED : TUE, JANUARY 11, 2022 @ 6:00 PM What’s changed for clinical labs as we enter the third year of COVID-19 testing? COVID-19, the illness caused by... Read more SARS-CoV-2 PANDEMIC REFLECTIONS: UNPRECEDENTED DEMAND DRIVES COVID-19 TEST DEVELOPERS TO GET CREATIVE UPDATED : TUE, DECEMBER 28, 2021 @ 3:30 PM What’s changed for clinical labs as we enter the third year of COVID-19 testing? COVID-19, the illness caused by... Read more Molecular diagnostics SARS-CoV-2 TECHNICAL BULLETIN: OMICRON IMPACT ON SARS-COV-2 MUTATION ANALYSIS AND INVESTIGATION Updated : Wed, March 22, 2023 @ 2:01 PM The emergence of the Omicron lineage has quickly escalated to be a variant of concern by the World Health Organization - Read more SARS-CoV-2 PANDEMIC REFLECTIONS: THE WORLD IS SHORT STAFFED UPDATED : THU, MARCH 9, 2023 @ 5:39 PM What’s changed for clinical labs as we enter the third year of COVID-19 testing? Read more Molecular diagnostics SARS-CoV-2 ENSURING OUR DIAGNOSTIC ASSAYS DETECT THE OMICRON VARIANT UPDATED : FRI, DECEMBER 10, 2021 @ 2:34 AM On 22 November 2021, The Network for Genomics Surveillance in South Africa detected a new SARS-CoV-2 variant, named... Read more Molecular diagnostics EXTENSIONS TO THE IVDR - WHAT DIAGNOSTICS MANUFACTURERS AND SUPPLIERS NEED TO KNOW We're excited to announce that the proposal to extend certain key provisions of the In Vitro Diagnostic Regulation (IVDR) (EU) 2017/746 has been adopted... Read more Molecular diagnostics SARS-CoV-2 Disease detection STREAMLINING DIAGNOSTIC WORKFLOWS FOR COMMON RESPIRATORY DISEASES, SUCH AS SARS-COV-2, INFLUENZA AND RSV UPDATED : TUE, NOVEMBER 30, 2021 @ 10:29 PM A fourth wave of COVID-19 has already emerged in many countries and a newly classified variant of concern, Omicron... Read more Molecular diagnostics Oligo synthesis and modifications INNOVATIVE APPLICATIONS FOR BLACK HOLE QUENCHER DYES UPDATED : TUE, JANUARY 25, 2022 @ 10:23 PM This is the first blog post in a two-part series highlighting how Black Hole Quencher™ dyes can be incorporated into... Read more Molecular diagnostics SARS-CoV-2 TECHNICAL BULLETIN: SARS-COV-2 MUTATION ANALYSIS AND INVESTIGATION Updated : Thu, October 14, 2021 @ 10:01 PM SARS-CoV-2 mutations and associated new variants are being reported regularly in the media and scientific... Read more Molecular diagnostics qPCR SARS-CoV-2 General science CAN COVID-19 TESTING BE MADE MORE SUSTAINABLE DURING PROLONGED UNCERTAINTY? UPDATED : THU, MARCH 31, 2022 @ 3:24 PM In September 2021, Delta persists as the most prevalent variant worldwide1 due to its high infectivity, causing surges... Read more Molecular diagnostics THE SURPRISING GLOBAL IMPACTS OF EUROPE'S IN VITRO DIAGNOSTIC REGULATION (IVDR) UPDATED : WED, SEPTEMBER 15, 2021 @ 4:40 AM A SHORTCUT TO UNDERSTANDING HOW TO PREPARE FOR IVDR In today’s global environment, even small regulatory changes in... Read more Molecular diagnostics SARS-CoV-2 TIPS FOR EARLY-STAGE MDX COMPANIES LAUNCHING NEW TESTS DURING COVID-19 TIMES UPDATED : WED, NOVEMBER 9, 2022 @ 8:20 PM The COVID-19 pandemic brought tremendous change to the molecular diagnostics (MDx) industry, delivering opportunities... Read more SARS-CoV-2 WASTEWATER SURVEILLANCE: A CRITICAL TOOL IN PANDEMIC MANAGEMENT Updated : Thu, September 29, 2022 @ 7:57 PM As SARS-CoV-2 variants continue to threaten public health, officials are looking beyond clinical tests to track... Read more SARS-CoV-2 TECHNICAL BULLETIN: EMERGING SARS-COV-2 MUTATIONS AND THEIR EFFECT ON THE IMMUNE RESPONSE UPDATED : THU, DECEMBER 16, 2021 @ 6:46 PM Emerging SARS-CoV-2 variants of concern and variants of interest are defined by agencies such as the World Health... Read more Molecular diagnostics Genomics SARS-CoV-2 General science GENOMIC SURVEILLANCE: 3 TECHNIQUES TO DETECT AND CHARACTERISE SARS-COV-2 VARIANTS UPDATED : THU, MARCH 9, 2023 @ 5:37 PM As the global population gains greater access to vaccines for COVID-19, scientists and health officials continue to... Read more Molecular diagnostics SARS-CoV-2 HOW DO SARS-COV-2 VARIANTS AFFECT PCR ASSAYS FOR COVID-19 TESTING? UPDATED : THU, MARCH 9, 2023 @ 5:34 PM Researchers have identified several variants of SARS-CoV-2 since they sequenced the original viral strain responsible... Read more Molecular diagnostics Genomics SARS-CoV-2 General science BUILDING RESILIENCE INTO SARS-COV-2 TESTING WORKFLOWS: CONSIDERATIONS FOR CHOOSING AN RNA ISOLATION METHOD UPDATED : THU, FEBRUARY 3, 2022 @ 4:39 PM Clinical and diagnostic labs worldwide are still experiencing supply chain challenges with their SARS-CoV-2 testing... Read more Molecular diagnostics Genomics SARS-CoV-2 PRESSING COVID-19 TESTING ISSUES OF TODAY AND THE NEAR FUTURE UPDATED : TUE, OCTOBER 6, 2020 @ 6:45 PM FOLLOWING UP WITH THE PANELISTS FROM OUR RECENT COVID-19 WEBINAR, PART 3 OF 3 In the previous two blog posts in this... Read more Molecular diagnostics Genomics SARS-CoV-2 SENSITIVITY AND ACCURACY IN COVID-19 TESTING UPDATED : TUE, OCTOBER 6, 2020 @ 6:42 PM FOLLOWING UP WITH THE PANELISTS FROM OUR RECENT COVID-19 WEBINAR, PART 2 OF 3 In the face of a rapidly evolving... Read more Molecular diagnostics Genomics SARS-CoV-2 SCALING UP COVID-19 VIRAL TESTING UPDATED : TUE, OCTOBER 6, 2020 @ 6:45 PM FOLLOWING UP WITH THE PANELISTS FROM OUR RECENT COVID-19 WEBINAR, PART 1 OF 3 The COVID-19 pandemic has presented... Read more Molecular diagnostics Genomics qPCR SARS-CoV-2 ENABLING A RAPID RESPONSE TO COVID-19 BY HONEYWELL AND LGC, BIOSEARCH TECHNOLOGIES UPDATED : TUE, OCTOBER 6, 2020 @ 6:44 PM As countries worldwide begin to ease lockdown restrictions during the pandemic and prepare to return to “normal”... Read more Molecular diagnostics Genomics qPCR SARS-CoV-2 ROBUST SUPPLY CHAINS AND OPEN TESTING SYSTEMS: HOW OUR AGBIO ROOTS MEET THE FDA'S EUA PROCESS TO ENABLE SOLUTIONS TO THE COVID-19 PANDEMIC Updated : Fri, December 18, 2020 @ 8:49 PM It may seem strange that a company known for transforming the global seed breeding industry is uniquely positioned... Read more Molecular diagnostics Oligo synthesis and modifications Genomics SARS-CoV-2 General science BEHIND THE SCENES: HOW OUR OLIGO SYNTHESIS TEAM CONTRIBUTES TO THE RELIABILITY OF YOUR ASSAYS UPDATED : WED, MARCH 22, 2023 @ 1:52 PM WE’RE NOT REJECTING YOU, JUST YOUR OLIGO PCR is arguably one of the most enabling technologies of modern molecular... Read more Molecular diagnostics SARS-CoV-2 WHEN YOU DON’T NEED AN EUA FOR SARS-COV-2 TESTING UPDATED : WED, NOVEMBER 25, 2020 @ 8:23 PM On March 25, 2020, the US Food and Drug Administration (FDA) held the first of a series of virtual town halls they... Read more Molecular diagnostics Oligo synthesis and modifications Genomics SARS-CoV-2 ADDRESSING COVID-19 TOGETHER: LGC, BIOSEARCH TECHNOLOGIES AND SHANGHAI LIFERIVER BIOTECHNOLOGY CO., LTD. Updated : Tue, October 6, 2020 @ 6:44 PM In the nearly three months since the first confirmed case of COVID-19, the outbreak has become a global crisis, with... Read more Molecular diagnostics Genomics SARS-CoV-2 General science WHAT DIAGNOSTIC TEST MAKERS AND CLIA LABS IN THE US NEED TO KNOW ABOUT EMERGENCY USE AUTHORIZATION (EUA) Updated : Tue, March 21, 2023 @ 3:41 PM *Since the original publication of this blog, LGC Biosearch Technologies is now the only acceptable commercial supplier... Read more Molecular diagnostics Genomics SARS-CoV-2 CORONAVIRUS OUTBREAK: COLLABORATION TO MEET THE CHALLENGE {% video_player "embed_player" overrideable=False, type='scriptV4', hide_playlist=True, viral_sharing=False, embed_button=False, autoplay=False,... Read more Molecular diagnostics Next generation sequencing (NGS) MOLECULAR DIAGNOSTICS: HOW CAN NGS LIVE UP TO ITS PROMISES? UPDATED : TUE, OCTOBER 11, 2022 @ 8:43 PM The development of new genomic sequencing techniques and bioinformatics analysis in the last decade has led to... Read more Genomics PCR-based genotyping Disease detection General science HOW GENOTYPING IS AIDING IN THE FIGHT AGAINST MALARIA Updated : Mon, September 19, 2022 @ 2:14 PM 3.2 billion people across 106 countries and territories, live in areas at risk of malaria transmission. The serious... Read more RNA FISH Disease detection General science SHINING A LIGHT ON HOW ZIKA VIRUS MAY SPREAD FROM MOTHERS TO HUMAN FETUSES UPDATED : MON, MARCH 6, 2017 @ 4:37 PM New research has, for the first time, found evidence suggesting the molecular epidemiology of how the Zika virus spreads... Read more Molecular diagnostics Oligo synthesis and modifications qPCR General science PHOTOBLOG: BEHIND THE SCENES OF OLIGO SYNTHESIS UPDATED : WED, DECEMBER 14, 2022 @ 5:04 PM OLIGO SYNTHESIS PHOTO GLIMPSE We’ve recently captured our talented manufacturing teams hard at work building... Read more Molecular diagnostics qPCR General science RT-QPCR MOLECULAR DIAGNOSTICS ASSIST WORKERS AT THE FOREFRONT OF EBOLA OUTBREAK. UPDATED : MON, SEPTEMBER 19, 2022 @ 2:13 PM The largest recorded Ebola Virus Disease outbreak in history continues to devastate the West African region. This... Read more Molecular diagnostics qPCR General science QPCR PROBES AT WORK: INNOVATIVE CLIA TEST FOR NSCLC STAGING UPDATED : WED, OCTOBER 1, 2014 @ 4:51 PM Non-squamous, Non-small cell lung cancer (NSCLC), the most common cause of death in the US and globally, has recently... Read more Molecular diagnostics VISIT BIOSEARCH AT IVD TECHNOLOGY'S VIRTUAL CONFERENCE AND TRADESHOW UPDATED : MON, SEPTEMBER 19, 2022 @ 2:07 PM Biosearch Technologies is proud to sponsor the first IVD Technology Virtual Conference and Tradeshow. This free... Read more Molecular diagnostics PILOTDX OLIGOS: EN ROUTE TO IVD UPDATED : WED, OCTOBER 1, 2014 @ 4:42 PM It can be difficult to transition a product from research to commercialization. It’s simply not feasible to conduct... Read more Agrigenomics NGS-based genotyping INCREASING LIVESTOCK BREEDING PROFITABILITY WITH GENOMIC SELECTION HOW DOES GENOMIC SELECTION INCREASE PROFITABILITY? Livestock farmers’ and breeders’ profitability is directly related to the quality of their stock. But this... Read more Agrigenomics NGS-based genotyping US DEPT OF AGRICULTURE DIVES INTO BLUEBERRY AND CRANBERRY GENOTYPING Every year over 1.5 million tonnes of blueberries and over half a million tonnes of cranberries are produced. This is expected to rise significantly over the... Read more Agrigenomics WHY GENOME-EDITING CRISPR/CAS OFFERS HOPE FOR ACCELERATED SUSTAINABLE CROP IMPROVEMENT IN OIL PALM Updated : Thu, June 1, 2023 @ 4:09 PM Oil palm, Elaeis guineensis Jacq., is the most productive oil crop in the world1 supplying around 40% of all globally... Read more Agrigenomics PCR-based genotyping ENHANCING STRAWBERRY BREEDING WITH PREDICTIVE MODELS, MARKER-ASSISTED SELECTION AND GENOTYPING AUTOMATION Updated : Tue, May 9, 2023 @ 10:48 AM Around 159,200 tonnes of strawberries are produced annually in Japan across 5,020 ha in various regions around the... Read more Agrigenomics PCR-based genotyping HOW MGB PROBES COULD SOLVE YOUR COMPLEX PLANT GENOME GENOTYPING ISSUES UPDATED : WED, MARCH 22, 2023 @ 1:48 PM Genotyping plants can be a complex and frustrating process Read more Agrigenomics PCR-based genotyping EXPLORE THE VAST APPLICATIONS OF KASP GENOTYPING FOR PLANT BREEDING PROGRAMMES UPDATED : WED, MARCH 22, 2023 @ 1:22 PM Modern agriculture faces unprecedented challenges: increasing global temperatures, water scarcity, less arable land to... Read more Agrigenomics PCR-based genotyping NGS-based genotyping GENETIC SOLUTIONS TO INFECTIOUS DISEASES IN AQUACULTURE Updated : Mon, April 17, 2023 @ 8:33 AM This is the second blog in a two-part series exploring solutions for infectious diseases in aquaculture. In the first... Read more Agrigenomics INCREASING RESISTANCE TO AQUACULTURE DISEASE Updated : Mon, April 17, 2023 @ 1:33 PM This is the first blog in a two-part series exploring solutions for infectious diseases in aquaculture. This blog post... Read more Agrigenomics qPCR PCR-based genotyping General science IMPROVING THE SUSTAINABILITY OF OIL PALM BREEDING PROGRAMMES USING MARKER-ASSISTED SELECTION UPDATED : WED, MARCH 9, 2022 @ 1:05 AM African oil palm (Elaeis guineensis Jacq.) is a highly productive perennial crop that is used widely in food, medicines,... Read more Agrigenomics qPCR PCR-based genotyping INCREASING HYBRID RICE BREEDING EFFICIENCY WITH HIGH-THROUGHPUT GENOTYPING Updated : Thu, January 12, 2023 @ 5:10 PM Rice is the primary staple for more than half the world's population.1 With so many people relying on the crop for... Read more Agrigenomics Next generation sequencing (NGS) NGS-based genotyping A TARGETED GBS TECHNOLOGY FOR ALL BREEDING COMMUNITIES UPDATED : TUE, DECEMBER 7, 2021 @ 10:11 PM The decisions made by molecular breeding programmes have a substantial impact on the world around us, from... Read more Agrigenomics NGS-based genotyping NGS SOLUTIONS FOR POLYPLOID PLANT BREEDING CHALLENGES Updated : Fri, June 30, 2023 @ 2:19 PM Many cultivated crops with agronomic significance, including wheat, peanut, oat, banana, potato, coffee, blueberry and... Read more Agrigenomics PCR-based genotyping Nucleic acid extraction 4 STEPS TO OPTIMISE SAMPLE COLLECTION FOR AQUACULTURE GENOTYPING Updated : Tue, September 7, 2021 @ 7:59 PM Aquaculture breeding programmes adopt genomic technologies, including genotyping, to increase genetic gain for... Read more Agrigenomics Next generation sequencing (NGS) Nucleic acid extraction THE IMPORTANCE OF SAMPLE PROCESSING FOR SUCCESSFUL PLANT GENOTYPING BY NGS UPDATED : THU, AUGUST 12, 2021 @ 11:51 PM Informed plant breeding decisions help drive the field of agrigenomics towards ever-increasing agricultural... Read more Agrigenomics Nucleic acid extraction DON'T UNDERESTIMATE THE COMPLEXITY OF YOUR SAMPLE COMPOSITION UPDATED : WED, AUGUST 4, 2021 @ 9:34 PM A common mistake when initiating an agrigenomics project is failing to consider specific sample composition before... Read more Agrigenomics Genomics General science SELECTIVE BREEDING IN AQUACULTURE: ADVANCING BREEDING PROGRAMMES THROUGH GENOMICS Updated : Wed, December 14, 2022 @ 1:44 PM The global demand for fish and fish products continues to increase as consumers focus on health-conscious ways to... Read more Agrigenomics Genomics NGS-based genotyping BEST PRACTICES FOR IMPLEMENTING TARGETED GENOTYPING BY SEQUENCING UPDATED : FRI, NOVEMBER 20, 2020 @ 5:16 PM In breeding programmes, selections based on a single or small number of markers to target traits in marker assisted... Read more Genomics PCR-based genotyping HOW HIGH-THROUGHPUT GENOTYPING AUTOMATION AND KASP MARKER LIBRARIES CONNECT RESEARCH LABS WITH COMMERCIAL BREEDERS TO ACCELERATE CROP IMPROVEMENT UPDATED : WED, OCTOBER 7, 2020 @ 4:33 PM “In July of 2015, I was a member of the radish genome project team. My task was to examine genetic diversity of radish... Read more Agrigenomics Genomics PCR-based genotyping EMPLOYEE SPOTLIGHT: MEET DARSHNA "DUSTY" VYAS UPDATED : FRI, SEPTEMBER 11, 2020 @ 9:52 PM Darshna "Dusty" Vyas has been a Senior Scientist at LGC specialising in plant genetics for the past 8 years Her... Read more Agrigenomics Genomics PCR-based genotyping ESTABLISHMENT OF KASP MARKER LIBRARY FOR GENETIC DIVERSITY ANALYSIS IN BRASSICA RAPA CROPS Updated : Tue, July 14, 2020 @ 1:30 PM Brassica rapa crops are important sources of food, feed, and fuel in many parts of the world and provide a unique... Read more Genomics Next generation sequencing (NGS) NGS-based genotyping NEW NGS SERVICE LAB NOW OPEN IN MIDDLETON, WI FOR EXPANDED GLOBAL SUPPORT UPDATED : WED, APRIL 1, 2020 @ 8:12 PM Back in September 2018, LGC acquired Lucigen Corporation. The ISO accredited site is based in Middleton, Wisconsin and... Read more Genomics PCR-based genotyping NGS-based genotyping BACK TO BASICS - THE CRUCIAL STEP OF SAMPLE COLLECTION UPDATED : MON, JANUARY 13, 2020 @ 5:08 PM BEST PRACTICE IN SAMPLE COLLECTION FOR SEQSNP TARGETED GENOTYPING BY SEQUENCING PROJECTS When good goes in, great... Read more Agrigenomics Genomics Next generation sequencing (NGS) NGS-based genotyping GENOMIC SELECTION: CAN IT ACCELERATE LIVESTOCK BREEDING? UPDATED : WED, MAY 1, 2019 @ 3:59 PM Livestock supports the livelihoods and food security of almost 1.3 billion people worldwide, contributing 40% of the... Read more Agrigenomics PCR-based genotyping Next generation sequencing (NGS) NGS-based genotyping AGRIGENOMICS: HOW CAN NGS CONTRIBUTE TO GLOBAL FOOD SECURITY? UPDATED : FRI, MAY 19, 2023 @ 8:53 AM “Experience of artificial fertilisation, such as is effected with ornamental plants in order to obtain new variations in... Read more Agrigenomics Next generation sequencing (NGS) NGS-based genotyping HOW TARGETED GBS-DRIVEN GENOMIC SELECTION CAN HELP YOU GET TO MARKET FASTER UPDATED : THU, MAY 25, 2023 @ 11:32 AM Plant and animal breeding programmes often take generations to improve quality and yield but using a genotyping protocol... Read more Genomics NGS-based genotyping GENOMIC SELECTION: METHODS IN CROP AND ANIMAL BREEDING UPDATED : WED, JANUARY 9, 2019 @ 5:03 PM Genomic selection: 6 factors to consider when choosing between targeted GBS and microarrays Read more Agrigenomics Next generation sequencing (NGS) NGS-based genotyping OUR HUNGRY PLANET: NEW TOOLS IN AGRIGENOMICS ARE KEY TO FOOD SECURITY UPDATED : TUE, DECEMBER 11, 2018 @ 4:32 PM Food security is a major global threat and traditional methods of plant and animal breeding will not be sufficient... Read more PCR-based genotyping ACCELERATING RICE IMPROVEMENT IN SOUTH ASIA Updated : Thu, July 26, 2018 @ 4:41 PM Diversity is the spice of life and is also key to breeding rice that delivers increased yields. Rice is a crucial staple... Read more Agrigenomics Genomics NGS-based genotyping General science TACKLING FOOD CRISIS THROUGH COST EFFECTIVE, TARGET ENRICHED SEQUENCING UPDATED : MON, SEPTEMBER 19, 2022 @ 2:16 PM With the global population predicted to reach 9 billion people within the next 35 years, we will need to double the... Read more Agrigenomics Genomics PCR-based genotyping NEW SNPS IDENTIFIED IN THE HUNT FOR NEW GENETIC WEAPONS TARGETING LEAF RUST IN WHEAT UPDATED : WED, NOVEMBER 22, 2017 @ 1:44 PM Wheat is one of the three most important crops for human and livestock feed. With an ever-increasing global... Read more Agrigenomics Genomics PCR-based genotyping SUPER-CROPS HELPING TO FEED AFRICA UPDATED : TUE, JULY 10, 2018 @ 9:08 PM Our world population is growing at a tremendous rate and by 2050, Africa’s population alone is set to hit over 2.5... Read more Genomics PCR-based genotyping Disease detection General science HOW GENOTYPING IS AIDING IN THE FIGHT AGAINST MALARIA Updated : Mon, September 19, 2022 @ 2:14 PM 3.2 billion people across 106 countries and territories, live in areas at risk of malaria transmission. The serious... Read more Genomics PCR-based genotyping General science OVERCOMING DROUGHT-INTOLERANCE IN MAIZE TO FEED THE GROWING ASIAN POPULATION UPDATED : WED, FEBRUARY 15, 2017 @ 4:23 PM Demand for maize is increasing due to an increased number of people transitioning to meat-based diets driving demand... Read more Agrigenomics Genomics PCR-based genotyping NGS-based genotyping General science HELPING TO FEED THE WORLD WITH GENOTYPING BY SEQUENCING UPDATED : WED, JANUARY 18, 2017 @ 2:13 PM Many areas critical to improved agricultural production require robust and scalable genotyping platforms to enable... Read more PCR-based genotyping FASTER, STRONGER, QUICKER: SSR TO KASP WILL GET YOU THERE UPDATED : MON, JANUARY 9, 2017 @ 3:20 PM Screen more markers faster and bring crops with superior traits to the market quicker. Read more Agrigenomics A COMPLETE ECOSYSTEM TO ACCELERATE BREEDING PROGRAMS [INFOGRAPHIC] UPDATED : TUE, JUNE 28, 2016 @ 9:00 PM Modern breeding methods rely on the identification and utilization of molecular markers associated with traits... Read more qPCR PCR-based genotyping General science A SUCCESSFUL DUO FOR ACCURATE, SPEEDY, AND ECONOMICAL SNP GENOTYPING UPDATED : MON, SEPTEMBER 19, 2022 @ 2:12 PM Single Nucleotide Polymorphisms (SNPs) have been widely studied for over 15 years, and have applications in... Read more Oligo synthesis and modifications Nucleic acid therapeutics SYNTHESIZING YOUR OWN OLIGONUCLEOTIDES: FAQS Considering bringing oligo synthesis in-house? Here are some commonly asked questions that we receive, grouped into four sections. You can jump to a section... Read more Oligo synthesis and modifications General science “CLICK” YOUR WAY TOWARDS DISCOVERY AND INNOVATION Labelling, linking or modifying biomolecules used to be a laborious process, requiring customised complex synthetic pathways that yield little product.... Read more Molecular diagnostics qPCR MINIMISING ANTIBIOTIC DEPENDENCY FOR TREATING UTIS AND STIS Antimicrobial resistance (AMR) across bacterial species is developing rapidly, compounded by the improper use of antimicrobial agents that accelerates the... Read more Oligo synthesis and modifications Nucleic acid therapeutics WHAT’S THE LATEST IN ASO AND SIRNA TECHNOLOGIES? Over the last few decades, researchers have made impressive strides in developing methods to overcome the delivery, stability, and specificity challenges of... Read more Molecular diagnostics Nucleic acid extraction DITCH THE SPIN COLUMNS WITHOUT COMPROMISING ON NUCLEIC ACID QUALITY Whether you’re working with samples for PCR or sequencing, it's worth questioning what type of extraction or purification method would work well with your... Read more Molecular diagnostics Oligo synthesis and modifications qPCR General science A WAY TO SIMPLIFY DESIGN AND INTERPRETATION OF YOUR QPCR ASSAYS UPDATED : FRI, MAY 5, 2023 @ 2:34 PM HOW DOES A BHQ DYE CONTRIBUTE TO PRODUCING SUPERIOR DATA FROM YOUR ASSAYS? Read more Oligo synthesis and modifications Nucleic acid therapeutics WHICH CONTROLLED PORE GLASS IS RIGHT FOR YOUR THERAPEUTIC APPLICATION? UPDATED : MON, JUNE 26, 2023 @ 10:24 AM Oligonucleotide therapeutics have unlocked new treatment possibilities for rare and fatal diseases often associated... Read more Oligo synthesis and modifications General science 5-NITROINDOLE – A UNIVERSAL BASE OLIGO MODIFICATION Updated : Tue, May 9, 2023 @ 10:51 AM In the next edition of the “Know your oligo mod” series, we look at a universal base analogue for oligonucleotide... Read more Molecular diagnostics Oligo synthesis and modifications WHAT’S NEXT FOR APTAMERS IN DIAGNOSTICS? UPDATED : TUE, MAY 9, 2023 @ 11:01 AM Originally developed in the early 1990s, aptamers have long been heralded as an antibody alternative for detection... Read more Molecular diagnostics Nucleic acid extraction General science HOW TO SELECT AN EFFECTIVE NUCLEIC ACID ISOLATION METHOD FOR HUMAN DIAGNOSTICS? Updated : Tue, May 9, 2023 @ 11:05 AM Molecular testing protocols for pathogen detection and diagnosing human diseases require reliable and high-quality... Read more qPCR General science TAQ POLYMERASE: WHAT IS IT AND ITS APPLICATIONS UPDATED : WED, DECEMBER 14, 2022 @ 1:54 PM When the polymerase chain reaction (PCR) was first described, the Klenow fragment of Escherichia coli DNA... Read more Oligo synthesis and modifications Nucleic acid therapeutics General science WHERE ARE ALL THE THERAPEUTIC APTAMERS? Updated : Tue, August 9, 2022 @ 7:10 PM New approaches that use aptamers as targeting agents may open the door to wider clinical use in the future Read more Molecular diagnostics Oligo synthesis and modifications qPCR General science CHOOSING THE BEST QPCR PROBE CHEMISTRY FOR YOUR ASSAY UPDATED : TUE, MAY 9, 2023 @ 10:40 AM LET THE APPLICATION BE YOUR GUIDE WHEN DECIDING BETWEEN LNA, MGB AND BHQPLUS The many different chemistries available... Read more SARS-CoV-2 Nucleic acid extraction Disease detection General science MAKE YOUR DIAGNOSTIC WORKFLOWS MORE ADAPTABLE UPDATED : FRI, DECEMBER 16, 2022 @ 3:39 PM Since early 2020, diagnostic laboratories have had to manage patient sample quantities being in a state of flux.... Read more Molecular diagnostics qPCR General science OPTIMISING AUTOMATED HIGH-THROUGHPUT PATHOGEN DETECTION WORKFLOWS UPDATED : WED, MARCH 30, 2022 @ 4:00 PM While both centralised and decentralised molecular diagnostics (MDx) testing models play an important role in patient... Read more Oligo synthesis and modifications Nucleic acid therapeutics OVERCOMING MANUFACTURING CHALLENGES ASSOCIATED WITH NUCLEIC ACID THERAPEUTICS Updated : Tue, March 21, 2023 @ 3:46 PM This is the second blog in a two-part series exploring how oligonucleotide modifications can support the advancement of... Read more Agrigenomics qPCR PCR-based genotyping General science IMPROVING THE SUSTAINABILITY OF OIL PALM BREEDING PROGRAMMES USING MARKER-ASSISTED SELECTION UPDATED : WED, MARCH 9, 2022 @ 1:05 AM African oil palm (Elaeis guineensis Jacq.) is a highly productive perennial crop that is used widely in food, medicines,... Read more Molecular diagnostics qPCR General science CONSIDERATIONS FOR RT-QPCR IN MOLECULAR POINT OF CARE TESTING DEVICES UPDATED : FRI, APRIL 15, 2022 @ 8:58 PM The COVID-19 pandemic has accelerated the uptake of point of care testing (POCT), with simple, user-administered tests... Read more Oligo synthesis and modifications Nucleic acid therapeutics NUCLEIC ACID THERAPEUTICS FOR NEXT-GENERATION DISEASE MANAGEMENT UPDATED : TUE, MARCH 21, 2023 @ 3:44 PM This is the first blog post in a two-part series exploring how oligonucleotide modifications can support the... Read more qPCR SARS-CoV-2 General science SOCIETY CAN’T HANDLE THE CAVEATS TO EACH TYPE OF COVID-19 TEST UPDATED : FRI, FEBRUARY 11, 2022 @ 10:58 PM BUT MEASUREMENT SCIENCE COULD HELP STEER US IN A BETTER, MORE INFORMED DIRECTION COVID-19 tests can indicate the... Read more Oligo synthesis and modifications LEVERAGING QUENCHING EFFICIENCY OF BLACK HOLE QUENCHER DYES FOR PCR AND BEYOND UPDATED : TUE, JANUARY 25, 2022 @ 8:30 PM MORE INNOVATIVE APPLICATIONS FOR BLACK HOLE QUENCHER (BHQ) DYES IN IMAGING AND DETECTION ASSAY DEVELOPMENT,... Read more RNA FISH General science FIVE WAYS CONTROLS CAN DEMYSTIFY YOUR STELLARIS™ RNA FISH EXPERIMENT UPDATED : WED, MARCH 22, 2023 @ 1:23 PM Stellaris controls, who needs ‘em? We all do. Especially if it’s your first time interrogating a sample with a new... Read more Agrigenomics qPCR PCR-based genotyping INCREASING HYBRID RICE BREEDING EFFICIENCY WITH HIGH-THROUGHPUT GENOTYPING Updated : Thu, January 12, 2023 @ 5:10 PM Rice is the primary staple for more than half the world's population.1 With so many people relying on the crop for... Read more Oligo synthesis and modifications General science OLIGONUCLEOTIDE SYNTHESIS BASICS: KEY TAKEAWAYS FOR POST-SYNTHESIS PROCESSING Updated : Wed, December 14, 2022 @ 4:45 PM This is the final blog post in a three-part educational series about best practices for in-house oligonucleotide... Read more Molecular diagnostics Oligo synthesis and modifications INNOVATIVE APPLICATIONS FOR BLACK HOLE QUENCHER DYES UPDATED : TUE, JANUARY 25, 2022 @ 10:23 PM This is the first blog post in a two-part series highlighting how Black Hole Quencher™ dyes can be incorporated into... Read more Oligo synthesis and modifications General science OLIGONUCLEOTIDE SYNTHESIS BASICS: 4 KEY TAKEAWAYS FOR IN-HOUSE OLIGO PRODUCTION Updated : Wed, December 14, 2022 @ 4:43 PM This is the second blog post in a three-part educational series about best practices for in-house oligonucleotide... Read more qPCR General science 8 QPCR AMPLIFICATION PLOT QUESTIONS ANSWERED Updated : Thu, February 3, 2022 @ 6:10 PM When results from your qPCR assays aren’t quite what you expected, it can be challenging to understand what went... Read more Molecular diagnostics qPCR SARS-CoV-2 General science CAN COVID-19 TESTING BE MADE MORE SUSTAINABLE DURING PROLONGED UNCERTAINTY? UPDATED : THU, MARCH 31, 2022 @ 3:24 PM In September 2021, Delta persists as the most prevalent variant worldwide1 due to its high infectivity, causing surges... Read more Oligo synthesis and modifications General science OLIGONUCLEOTIDE SYNTHESIS BASICS: INTRODUCTION TO PHOSPHORAMIDITE CHEMISTRY UPDATED : WED, DECEMBER 14, 2022 @ 4:43 PM This is the first blog post in a three-part educational series about best practices for in-house oligonucleotide... Read more Agrigenomics PCR-based genotyping Nucleic acid extraction 4 STEPS TO OPTIMISE SAMPLE COLLECTION FOR AQUACULTURE GENOTYPING Updated : Tue, September 7, 2021 @ 7:59 PM Aquaculture breeding programmes adopt genomic technologies, including genotyping, to increase genetic gain for... Read more Agrigenomics Next generation sequencing (NGS) Nucleic acid extraction THE IMPORTANCE OF SAMPLE PROCESSING FOR SUCCESSFUL PLANT GENOTYPING BY NGS UPDATED : THU, AUGUST 12, 2021 @ 11:51 PM Informed plant breeding decisions help drive the field of agrigenomics towards ever-increasing agricultural... Read more Agrigenomics Nucleic acid extraction DON'T UNDERESTIMATE THE COMPLEXITY OF YOUR SAMPLE COMPOSITION UPDATED : WED, AUGUST 4, 2021 @ 9:34 PM A common mistake when initiating an agrigenomics project is failing to consider specific sample composition before... Read more Agrigenomics Genomics General science SELECTIVE BREEDING IN AQUACULTURE: ADVANCING BREEDING PROGRAMMES THROUGH GENOMICS Updated : Wed, December 14, 2022 @ 1:44 PM The global demand for fish and fish products continues to increase as consumers focus on health-conscious ways to... Read more Molecular diagnostics Genomics SARS-CoV-2 General science GENOMIC SURVEILLANCE: 3 TECHNIQUES TO DETECT AND CHARACTERISE SARS-COV-2 VARIANTS UPDATED : THU, MARCH 9, 2023 @ 5:37 PM As the global population gains greater access to vaccines for COVID-19, scientists and health officials continue to... Read more Agrigenomics Genomics NGS-based genotyping BEST PRACTICES FOR IMPLEMENTING TARGETED GENOTYPING BY SEQUENCING UPDATED : FRI, NOVEMBER 20, 2020 @ 5:16 PM In breeding programmes, selections based on a single or small number of markers to target traits in marker assisted... Read more Molecular diagnostics Genomics SARS-CoV-2 General science BUILDING RESILIENCE INTO SARS-COV-2 TESTING WORKFLOWS: CONSIDERATIONS FOR CHOOSING AN RNA ISOLATION METHOD UPDATED : THU, FEBRUARY 3, 2022 @ 4:39 PM Clinical and diagnostic labs worldwide are still experiencing supply chain challenges with their SARS-CoV-2 testing... Read more Genomics PCR-based genotyping HOW HIGH-THROUGHPUT GENOTYPING AUTOMATION AND KASP MARKER LIBRARIES CONNECT RESEARCH LABS WITH COMMERCIAL BREEDERS TO ACCELERATE CROP IMPROVEMENT UPDATED : WED, OCTOBER 7, 2020 @ 4:33 PM “In July of 2015, I was a member of the radish genome project team. My task was to examine genetic diversity of radish... Read more Agrigenomics Genomics PCR-based genotyping EMPLOYEE SPOTLIGHT: MEET DARSHNA "DUSTY" VYAS UPDATED : FRI, SEPTEMBER 11, 2020 @ 9:52 PM Darshna "Dusty" Vyas has been a Senior Scientist at LGC specialising in plant genetics for the past 8 years Her... Read more Molecular diagnostics Genomics SARS-CoV-2 PRESSING COVID-19 TESTING ISSUES OF TODAY AND THE NEAR FUTURE UPDATED : TUE, OCTOBER 6, 2020 @ 6:45 PM FOLLOWING UP WITH THE PANELISTS FROM OUR RECENT COVID-19 WEBINAR, PART 3 OF 3 In the previous two blog posts in this... Read more Molecular diagnostics Genomics SARS-CoV-2 SENSITIVITY AND ACCURACY IN COVID-19 TESTING UPDATED : TUE, OCTOBER 6, 2020 @ 6:42 PM FOLLOWING UP WITH THE PANELISTS FROM OUR RECENT COVID-19 WEBINAR, PART 2 OF 3 In the face of a rapidly evolving... Read more Molecular diagnostics Genomics SARS-CoV-2 SCALING UP COVID-19 VIRAL TESTING UPDATED : TUE, OCTOBER 6, 2020 @ 6:45 PM FOLLOWING UP WITH THE PANELISTS FROM OUR RECENT COVID-19 WEBINAR, PART 1 OF 3 The COVID-19 pandemic has presented... Read more Molecular diagnostics Genomics qPCR SARS-CoV-2 ENABLING A RAPID RESPONSE TO COVID-19 BY HONEYWELL AND LGC, BIOSEARCH TECHNOLOGIES UPDATED : TUE, OCTOBER 6, 2020 @ 6:44 PM As countries worldwide begin to ease lockdown restrictions during the pandemic and prepare to return to “normal”... Read more Agrigenomics Genomics PCR-based genotyping ESTABLISHMENT OF KASP MARKER LIBRARY FOR GENETIC DIVERSITY ANALYSIS IN BRASSICA RAPA CROPS Updated : Tue, July 14, 2020 @ 1:30 PM Brassica rapa crops are important sources of food, feed, and fuel in many parts of the world and provide a unique... Read more Molecular diagnostics Genomics qPCR SARS-CoV-2 ROBUST SUPPLY CHAINS AND OPEN TESTING SYSTEMS: HOW OUR AGBIO ROOTS MEET THE FDA'S EUA PROCESS TO ENABLE SOLUTIONS TO THE COVID-19 PANDEMIC Updated : Fri, December 18, 2020 @ 8:49 PM It may seem strange that a company known for transforming the global seed breeding industry is uniquely positioned... Read more Molecular diagnostics Oligo synthesis and modifications Genomics SARS-CoV-2 General science BEHIND THE SCENES: HOW OUR OLIGO SYNTHESIS TEAM CONTRIBUTES TO THE RELIABILITY OF YOUR ASSAYS UPDATED : WED, MARCH 22, 2023 @ 1:52 PM WE’RE NOT REJECTING YOU, JUST YOUR OLIGO PCR is arguably one of the most enabling technologies of modern molecular... Read more Genomics Next generation sequencing (NGS) NGS-based genotyping NEW NGS SERVICE LAB NOW OPEN IN MIDDLETON, WI FOR EXPANDED GLOBAL SUPPORT UPDATED : WED, APRIL 1, 2020 @ 8:12 PM Back in September 2018, LGC acquired Lucigen Corporation. The ISO accredited site is based in Middleton, Wisconsin and... Read more Molecular diagnostics Oligo synthesis and modifications Genomics SARS-CoV-2 ADDRESSING COVID-19 TOGETHER: LGC, BIOSEARCH TECHNOLOGIES AND SHANGHAI LIFERIVER BIOTECHNOLOGY CO., LTD. Updated : Tue, October 6, 2020 @ 6:44 PM In the nearly three months since the first confirmed case of COVID-19, the outbreak has become a global crisis, with... Read more Molecular diagnostics Genomics SARS-CoV-2 General science WHAT DIAGNOSTIC TEST MAKERS AND CLIA LABS IN THE US NEED TO KNOW ABOUT EMERGENCY USE AUTHORIZATION (EUA) Updated : Tue, March 21, 2023 @ 3:41 PM *Since the original publication of this blog, LGC Biosearch Technologies is now the only acceptable commercial supplier... Read more Molecular diagnostics Genomics SARS-CoV-2 CORONAVIRUS OUTBREAK: COLLABORATION TO MEET THE CHALLENGE {% video_player "embed_player" overrideable=False, type='scriptV4', hide_playlist=True, viral_sharing=False, embed_button=False, autoplay=False,... Read more Genomics PCR-based genotyping NGS-based genotyping BACK TO BASICS - THE CRUCIAL STEP OF SAMPLE COLLECTION UPDATED : MON, JANUARY 13, 2020 @ 5:08 PM BEST PRACTICE IN SAMPLE COLLECTION FOR SEQSNP TARGETED GENOTYPING BY SEQUENCING PROJECTS When good goes in, great... Read more Agrigenomics Genomics Next generation sequencing (NGS) NGS-based genotyping GENOMIC SELECTION: CAN IT ACCELERATE LIVESTOCK BREEDING? UPDATED : WED, MAY 1, 2019 @ 3:59 PM Livestock supports the livelihoods and food security of almost 1.3 billion people worldwide, contributing 40% of the... Read more Genomics THE WOMEN OF LGC, BIOSEARCH TECHNOLOGIES UPDATED : FRI, MARCH 29, 2019 @ 4:39 PM We've heard it said for years, "TV will rot your brain". But in the case of our three colleagues below, that definitely... Read more Genomics NGS-based genotyping GENOMIC SELECTION: METHODS IN CROP AND ANIMAL BREEDING UPDATED : WED, JANUARY 9, 2019 @ 5:03 PM Genomic selection: 6 factors to consider when choosing between targeted GBS and microarrays Read more Genomics General science REVOLUTIONISING CANCER TREATMENT ONE ARRAY AT A TIME UPDATED : MON, SEPTEMBER 19, 2022 @ 2:14 PM While the science of pharmacogenomics has been around for years, its popularity is starting to pick up steam as... Read more Genomics Nucleic acid extraction PACK IT UP, PACK IT IN, LET ME BEGIN: A LOOK AT THE FUTURE OF DNA DATA STORAGE UPDATED : THU, JUNE 28, 2018 @ 4:28 PM Imagine a time capsule the size of a shoebox that holds all the information currently on the internet that can be stored... Read more RNA FISH Genomics WARNING! PITFALLS AHEAD: HOW TO AVOID THE MOST COMMON STELLARIS RNA FISH MISTAKES UPDATED : TUE, MAY 29, 2018 @ 3:47 PM Ever wake up in the morning just feeling like a rock star, or maybe like Francis Crick, Rosalind Franklin or Maurice... Read more RNA FISH Genomics SHINING A LIGHT ON GENE EXPRESSION AND REGULATION ONE CELL AT A TIME UPDATED : MON, APRIL 30, 2018 @ 1:53 PM To truly understand complex diseases such as cancer, scientists need access to tools that don’t just average data... Read more Genomics THE WOMEN OF LGC UPDATED : THU, MARCH 29, 2018 @ 4:00 PM Ask any little girl what they want to be when they grow up and you may hear things like, princess, ballerina, pop star,... Read more RNA FISH Genomics IN CASE YOU MISSED IT: STELLARIS RNA FISH LUNCH-AND-LEARN UPDATED : TUE, JANUARY 16, 2018 @ 4:50 PM Stellaris® RNA FISH (fluorescence in situ hybridization) is an RNA visualization method that allows simultaneous... Read more Agrigenomics Genomics NGS-based genotyping General science TACKLING FOOD CRISIS THROUGH COST EFFECTIVE, TARGET ENRICHED SEQUENCING UPDATED : MON, SEPTEMBER 19, 2022 @ 2:16 PM With the global population predicted to reach 9 billion people within the next 35 years, we will need to double the... Read more Agrigenomics Genomics PCR-based genotyping NEW SNPS IDENTIFIED IN THE HUNT FOR NEW GENETIC WEAPONS TARGETING LEAF RUST IN WHEAT UPDATED : WED, NOVEMBER 22, 2017 @ 1:44 PM Wheat is one of the three most important crops for human and livestock feed. With an ever-increasing global... Read more Agrigenomics Genomics PCR-based genotyping SUPER-CROPS HELPING TO FEED AFRICA UPDATED : TUE, JULY 10, 2018 @ 9:08 PM Our world population is growing at a tremendous rate and by 2050, Africa’s population alone is set to hit over 2.5... Read more Genomics PCR-based genotyping Disease detection General science HOW GENOTYPING IS AIDING IN THE FIGHT AGAINST MALARIA Updated : Mon, September 19, 2022 @ 2:14 PM 3.2 billion people across 106 countries and territories, live in areas at risk of malaria transmission. The serious... Read more RNA FISH Genomics General science LUNCH & LEARN: STELLARIS RNA FISH UPDATED : THU, JULY 6, 2017 @ 3:22 PM Recently LGC Genomics hosted a lunch and learn Stellaris® seminar at the Helen Diller Cancer Institute at UCSF with our... Read more Genomics qPCR General science IT’S OFFICIAL! PERSONAL HEALTH BECOMES FIRST CHINA DEMONSTRATION LABORATORY SITE FOR LGC’S NEXAR SYSTEM Updated : Mon, September 19, 2022 @ 2:07 PM LGC's Genomics Division has signed a memorandum of understanding (MOU) with Chinese health management expert... Read more qPCR General science DIGITAL PCR – IMPROVING REPRODUCIBLE MOLECULAR METHODS IN THE CLINIC UPDATED : THU, APRIL 6, 2017 @ 3:40 PM A recent study coordinated by LGC and published in the journal Analytical Chemistry, has demonstrated the potential of... Read more RNA FISH Disease detection General science SHINING A LIGHT ON HOW ZIKA VIRUS MAY SPREAD FROM MOTHERS TO HUMAN FETUSES UPDATED : MON, MARCH 6, 2017 @ 4:37 PM New research has, for the first time, found evidence suggesting the molecular epidemiology of how the Zika virus spreads... Read more Genomics PCR-based genotyping General science OVERCOMING DROUGHT-INTOLERANCE IN MAIZE TO FEED THE GROWING ASIAN POPULATION UPDATED : WED, FEBRUARY 15, 2017 @ 4:23 PM Demand for maize is increasing due to an increased number of people transitioning to meat-based diets driving demand... Read more Genomics General science AUTOMATE TO ACCELERATE AND SCALE-UP SNP-BASED GENOTYPING WORKFLOWS! UPDATED : MON, SEPTEMBER 19, 2022 @ 2:05 PM The advent of and ongoing improvements to next-generation sequencing technologies is driving the continuing and... Read more Genomics General science MULTIPLE MISUNDERSTANDINGS: LEARNING FROM GENETIC DETERMINISM UPDATED : MON, JANUARY 23, 2017 @ 4:27 PM Nature versus nurture. It’s a tale as old as time. When Craig Venter made the comment after the human genome sequence... Read more Agrigenomics Genomics PCR-based genotyping NGS-based genotyping General science HELPING TO FEED THE WORLD WITH GENOTYPING BY SEQUENCING UPDATED : WED, JANUARY 18, 2017 @ 2:13 PM Many areas critical to improved agricultural production require robust and scalable genotyping platforms to enable... Read more Genomics qPCR General science MULTIPLEX YOUR QPCR AND WALK-AWAY UPDATED : MON, SEPTEMBER 19, 2022 @ 2:15 PM It seems everyone wants to do more with less, and automate the process as well. But this can cause a number of... Read more RNA FISH Genomics General science A STELLAR-IS YEAR IN THE MAKING UPDATED : MON, SEPTEMBER 19, 2022 @ 2:12 PM It wouldn't be fair to close out 2016 without showcasing the stellar year that Stellaris® RNA FISH has had. Take a... Read more Genomics General science BUDDY UP: THE DOUBLE HELIX UPDATED : MON, NOVEMBER 28, 2016 @ 11:31 PM The secret of life. That’s what Francis Crick and James Watson claimed they had discovered back in Cambridge,... Read more Genomics General science GENES, PROTEINS & DNA: OUR HEREDITARY SOFTWARE UPDATED : MON, NOVEMBER 21, 2016 @ 3:32 PM In the early 1900s, scientists found that the function of genes was to make proteins, disproving the earlier idea... Read more Genomics General science "X" MARKS THE SPOT: A CLOSER LOOK AT CHROMOSOMES UPDATED : WED, MARCH 29, 2023 @ 10:51 AM The strands of DNA in your cells are organized into pieces called chromosomes. Chromosomes are further organized into... Read more Genomics General science EXCEL AUTOCORRECT FAILS THE GENOMICS COMMUNITY - ARE YOUR RESULTS EXCELLENT OR EXCEL-NOT? UPDATED : MON, SEPTEMBER 19, 2022 @ 2:13 PM Researchers from the Baker IDI Heart and Diabetes Institute in Melbourne, Australia have blamed a default... Read more qPCR General science QPCR-BASED MOLECULAR DIAGNOSTICS AT THE FOREFRONT OF ZIKA SURVEILLANCE UPDATED : WED, MARCH 29, 2023 @ 11:04 AM As the Zika virus outbreak spreads, a wave of international concern has grown, and scientists have scrambled to... Read more Oligo synthesis and modifications General science KNOW YOUR OLIGO MOD: THIO C6 LINKER UPDATED : WED, MARCH 29, 2023 @ 10:55 AM THIO C6 LINKER (THIOHEXYL) We continue our “Know Your Oligo Mod” series with another versatile custom oligonucleotide... Read more Molecular diagnostics Oligo synthesis and modifications qPCR General science PHOTOBLOG: BEHIND THE SCENES OF OLIGO SYNTHESIS UPDATED : WED, DECEMBER 14, 2022 @ 5:04 PM OLIGO SYNTHESIS PHOTO GLIMPSE We’ve recently captured our talented manufacturing teams hard at work building... Read more qPCR General science NOVA IS THE NEW BLACK Updated : Mon, April 24, 2023 @ 8:54 AM LGC Biosearch Technologies has developed a new qPCR probe format powered by Black Hole Quencher™ technology known as ... Read more RNA FISH General science IMAGING STELLARIS ASSAYS PART III: CREATING PROFESSIONAL, PUBLICATION-READY IMAGES Updated : Wed, August 16, 2017 @ 9:15 AM Here is the final installment of our “Imaging Stellaris Assays” blog series. In our two previous posts, we’ve gone... Read more RNA FISH General science DESIGNING STELLARIS RNA FISH PROBES PART I: INCREASING PROBE COUNT Updated : Tue, September 27, 2022 @ 2:32 PM Stellaris® RNA FISH is a novel technology that allows for the detection of single or clustered RNAs in fixed cells... Read more Oligo synthesis and modifications qPCR General science KNOW YOUR OLIGO MOD: 3' SPACER C3 UPDATED : WED, MARCH 29, 2023 @ 10:54 AM This week, we continue our Know your oligo mod blog series and we will focus on a very basic, yet extremely versatile... Read more RNA FISH General science IMAGING STELLARIS ASSAYS PART II: HOW TO ACQUIRE STUNNING IMAGES UPDATED : WED, AUGUST 16, 2017 @ 9:13 AM Here we continue our “Imaging Stellaris Assays” blog series. We last left off talking about the most important... Read more RNA FISH General science RUNAWAY RNA STAYS PUT UPDATED : TUE, MARCH 21, 2023 @ 3:53 PM The cleavage and polyadenylation event, the final trimming in the molecular mRNA barbershop, normally releases both the... Read more RNA FISH General science IMAGING STELLARIS ASSAYS PART I: GET TO KNOW YOUR MICROSCOPE UPDATED : WED, AUGUST 16, 2017 @ 9:42 PM Stellaris® FISH is an RNA detection technology performed by means of in situ hybridization. This technology and all of... Read more Oligo synthesis and modifications General science THE AGCT’S OF DNA SYNTHESIS UPDATED : WED, MARCH 29, 2023 @ 10:38 AM Chemically synthesized DNA has become an indispensable tool for molecular biologists in the fields of medicine,... Read more Oligo synthesis and modifications General science KNOW YOUR OLIGO MOD: BHQ® (BLACK HOLE QUENCHER®) NON-FLUORESCENT QUENCHERS UPDATED : FRI, JANUARY 13, 2023 @ 11:35 AM In this instalment, we will cover the basics of LGC Biosearch Technologies’ line of proprietary non-fluorescent... Read more RNA FISH qPCR General science AND THE CONSENSUS (SEQUENCE) IS... UPDATED : FRI, NOVEMBER 13, 2015 @ 9:25 PM Studying the expression level of RNA transcripts is often complicated by the fact that many DNA sequences are... Read more RNA FISH General science RESEARCH HIGHLIGHT: BRINGING VISION RESEARCH INTO FOCUS UPDATED : TUE, MARCH 21, 2023 @ 3:37 PM Gene expression and molecular biology research in vision and ophthalmology presents unique challenges to researchers... Read more RNA FISH General science FISH-ING FOR FUSIONS: A UNIQUE APPROACH TO FUSION GENE MRNA & PRE-MRNA DETECTION IN CANCER UPDATED : FRI, NOVEMBER 13, 2015 @ 10:27 PM This past April, Biosearch attended the American Association of Cancer Research (AACR) conference in Philadelphia,... Read more qPCR General science HOW MUCH IS YOUR QPCR ASSAY REALLY COSTING YOU? UPDATED : FRI, NOVEMBER 13, 2015 @ 10:40 PM In the setup of a qPCR experiment, one of the first decisions to make is which detection method to use. This... Read more RNA FISH General science THE 4CS OF STELLARIS® RNA FISH BUFFERS UPDATED : MON, NOVEMBER 16, 2015 @ 3:55 PM Buffers are often overlooked and taken for granted until the day comes when a peculiar result is observed and its... Read more Oligo synthesis and modifications General science KNOW YOUR OLIGO MOD: PHOSPHOROTHIOATE BONDS UPDATED : WED, MARCH 29, 2023 @ 10:56 AM This post in our continuing series, “Know your oligo mod” will cover phosphorothioate bonds, which are available for... Read more qPCR General science OPTIMISING MULTIPLEX COMPETITIVE QRT-PCR IN DIAGNOSTICS WITH BHQPLUS PROBES UPDATED : MON, NOVEMBER 16, 2015 @ 5:30 PM In a webinar linked below, Dr. James Willey describes a two colour fluorometric assay for more robust quantitation... Read more qPCR PCR-based genotyping General science A SUCCESSFUL DUO FOR ACCURATE, SPEEDY, AND ECONOMICAL SNP GENOTYPING UPDATED : MON, SEPTEMBER 19, 2022 @ 2:12 PM Single Nucleotide Polymorphisms (SNPs) have been widely studied for over 15 years, and have applications in... Read more Oligo synthesis and modifications General science KNOW YOUR OLIGO MOD: METHYLENE BLUE UPDATED : WED, MARCH 29, 2023 @ 10:56 AM The chemical synthesis of oligonucleotides allows for the incorporation of a wealth of modifications to an oligo... Read more RNA FISH General science UNRAVELING THE NEURAL WEB: STELLARIS® RNA FISH FOR NEUROSCIENCE RESEARCH UPDATED : MON, SEPTEMBER 19, 2022 @ 2:14 PM Neuroscience gene expression research can come with many hurdles, especially when working with brain tissue or... Read more qPCR General science CHECK OUT OUR NEW WEBSITE QPCR DESIGN LAB @ QPCRDESIGN.COM UPDATED : TUE, MARCH 28, 2023 @ 9:02 PM Biosearch Technologies has launched qPCRdesign.com, a microsite targeted specifically for your quantitative PCR... Read more Load more Follow us on Twiiter BIOSEARCHTECH BLOG ALERTS Don’t forget to subscribe to the latest scientific content curated by scientists for scientists. You’ll receive an email twice a month or less. Your Email:* Lifecycle Stage SUBSCRIBE TO OUR BLOG Your Email:* Notification Frequency* * Monthly * Instant * Daily * Weekly Lifecycle Stage ABOUT LGC, BIOSEARCH TECHNOLOGIES LGC, Biosearch Technologies is the complete Genomics portfolio from LGC. Providing genomic analysis tools, instrumentation and services to the genomic scientific discovery sector worldwide, with focus on across ag bio, pharma and molecular diagnostics. Visit our home page to view our products and services. 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