blog.biosearchtech.com Open in urlscan Pro
2606:2c40::c73c:671f  Public Scan

Submitted URL: http://blog.biosearchtech.com/
Effective URL: https://blog.biosearchtech.com/
Submission: On November 22 via api from US — Scanned from DE

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Oligo synthesis and modifications Nucleic acid therapeutics


OVERCOMING MANUFACTURING CHALLENGES ASSOCIATED WITH NUCLEIC ACID THERAPEUTICS

Posted on Thu, Mar 24, 2022 @ 06:15 PM

Updated : Tue, March 21, 2023 @ 3:46 PM

This is the second blog in a two-part series exploring how oligonucleotide...

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Agrigenomics qPCR PCR-based genotyping


IMPROVING THE SUSTAINABILITY OF OIL PALM BREEDING PROGRAMMES USING
MARKER-ASSISTED SELECTION

Posted on Tue, Mar 08, 2022 @ 03:00 PM

UPDATED : WED, MARCH 9, 2022 @ 1:05 AM

African oil palm (Elaeis guineensis Jacq.) is a highly productive perennial
crop...

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Molecular diagnostics qPCR


CONSIDERATIONS FOR RT-QPCR IN MOLECULAR POINT OF CARE TESTING DEVICES

Posted on Tue, Mar 01, 2022 @ 03:11 PM

UPDATED : FRI, APRIL 15, 2022 @ 8:58 PM

The COVID-19 pandemic has accelerated the uptake of point of care testing...

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Oligo synthesis and modifications Nucleic acid therapeutics


NUCLEIC ACID THERAPEUTICS FOR NEXT-GENERATION DISEASE MANAGEMENT

Posted on Fri, Feb 25, 2022 @ 02:47 PM

UPDATED : TUE, MARCH 21, 2023 @ 3:44 PM

This is the first blog post in a two-part series exploring how
oligonucleotide...

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qPCR SARS-CoV-2


SOCIETY CAN’T HANDLE THE CAVEATS TO EACH TYPE OF COVID-19 TEST

Posted on Fri, Feb 11, 2022 @ 04:58 PM


UPDATED : FRI, FEBRUARY 11, 2022 @ 10:58 PM


BUT MEASUREMENT SCIENCE COULD HELP STEER US IN A BETTER, MORE INFORMED...

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Oligo synthesis and modifications


LEVERAGING QUENCHING EFFICIENCY OF BLACK HOLE QUENCHER DYES FOR PCR AND BEYOND

Posted on Tue, Jan 25, 2022 @ 02:30 PM


UPDATED : TUE, JANUARY 25, 2022 @ 8:30 PM


MORE INNOVATIVE APPLICATIONS FOR BLACK HOLE QUENCHER (BHQ) DYES


IN IMAGING...

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RNA FISH


FIVE WAYS CONTROLS CAN DEMYSTIFY YOUR STELLARIS™ RNA FISH EXPERIMENT

Posted on Sun, Jan 23, 2022 @ 06:14 AM

UPDATED : WED, MARCH 22, 2023 @ 1:23 PM

Stellaris controls, who needs ‘em? We all do. Especially if it’s your first...

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Agrigenomics qPCR PCR-based genotyping


INCREASING HYBRID RICE BREEDING EFFICIENCY WITH HIGH-THROUGHPUT GENOTYPING

Posted on Tue, Jan 18, 2022 @ 03:03 PM

Updated : Thu, January 12, 2023 @ 5:10 PM

Rice is the primary staple for more than half the world's population.1 With...

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SARS-CoV-2


PANDEMIC REFLECTIONS: IN THE FACE OF SARS-COV-2 VARIANTS, COVID-19 TESTING
REMAINS ESSENTIAL

Posted on Tue, Jan 11, 2022 @ 12:00 PM

UPDATED : TUE, JANUARY 11, 2022 @ 6:00 PM

What’s changed for clinical labs as we enter the third year of COVID-19...

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SARS-CoV-2


PANDEMIC REFLECTIONS: UNPRECEDENTED DEMAND DRIVES COVID-19 TEST DEVELOPERS TO
GET CREATIVE

Posted on Tue, Dec 28, 2021 @ 09:30 AM

UPDATED : TUE, DECEMBER 28, 2021 @ 3:30 PM

What’s changed for clinical labs as we enter the third year of COVID-19...

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Molecular diagnostics SARS-CoV-2


TECHNICAL BULLETIN: OMICRON IMPACT ON SARS-COV-2 MUTATION ANALYSIS AND
INVESTIGATION

Posted on Thu, Dec 23, 2021 @ 11:45 AM

Updated : Wed, March 22, 2023 @ 2:01 PM

The emergence of the Omicron lineage has quickly escalated to be a variant of...

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SARS-CoV-2


PANDEMIC REFLECTIONS: THE WORLD IS SHORT STAFFED

Posted on Tue, Dec 21, 2021 @ 06:52 PM

UPDATED : THU, MARCH 9, 2023 @ 5:39 PM

What’s changed for clinical labs as we enter the third year of COVID-19 testing?

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Oligo synthesis and modifications


OLIGONUCLEOTIDE SYNTHESIS BASICS: KEY TAKEAWAYS FOR POST-SYNTHESIS PROCESSING

Posted on Thu, Dec 16, 2021 @ 04:39 PM

Updated : Wed, December 14, 2022 @ 4:45 PM

This is the final blog post in a three-part educational series about best...

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Molecular diagnostics SARS-CoV-2


ENSURING OUR DIAGNOSTIC ASSAYS DETECT THE OMICRON VARIANT

Posted on Thu, Dec 09, 2021 @ 04:24 PM

UPDATED : FRI, DECEMBER 10, 2021 @ 2:34 AM

On 22 November 2021, The Network for Genomics Surveillance in South Africa...

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Agrigenomics Next generation sequencing (NGS) NGS-based genotyping


A TARGETED GBS TECHNOLOGY FOR ALL BREEDING COMMUNITIES

Posted on Tue, Dec 07, 2021 @ 04:11 PM

UPDATED : TUE, DECEMBER 7, 2021 @ 10:11 PM

The decisions made by molecular breeding programmes have a substantial...

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Molecular diagnostics


EXTENSIONS TO THE IVDR - WHAT DIAGNOSTICS MANUFACTURERS AND SUPPLIERS NEED TO
KNOW

Posted on Thu, Dec 02, 2021 @ 05:25 PM

We're excited to announce that the proposal to extend certain key provisions of
the In Vitro Diagnostic Regulation...

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Molecular diagnostics SARS-CoV-2 Disease detection


STREAMLINING DIAGNOSTIC WORKFLOWS FOR COMMON RESPIRATORY DISEASES, SUCH AS
SARS-COV-2, INFLUENZA AND RSV

Posted on Tue, Nov 30, 2021 @ 04:29 PM

UPDATED : TUE, NOVEMBER 30, 2021 @ 10:29 PM

A fourth wave of COVID-19 has already emerged in many countries and a newly...

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Agrigenomics NGS-based genotyping


NGS SOLUTIONS FOR POLYPLOID PLANT BREEDING CHALLENGES

Posted on Tue, Nov 23, 2021 @ 09:00 AM

Updated : Fri, June 30, 2023 @ 2:19 PM

Many cultivated crops with agronomic significance, including wheat, peanut,
oat,...

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Molecular diagnostics Oligo synthesis and modifications


INNOVATIVE APPLICATIONS FOR BLACK HOLE QUENCHER DYES

Posted on Tue, Nov 16, 2021 @ 04:14 PM

UPDATED : TUE, JANUARY 25, 2022 @ 10:23 PM

This is the first blog post in a two-part series highlighting how Black Hole...

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Oligo synthesis and modifications


OLIGONUCLEOTIDE SYNTHESIS BASICS: 4 KEY TAKEAWAYS FOR IN-HOUSE OLIGO PRODUCTION

Posted on Tue, Nov 02, 2021 @ 11:41 AM

Updated : Wed, December 14, 2022 @ 4:43 PM

This is the second blog post in a three-part educational series about best...

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Molecular diagnostics SARS-CoV-2


TECHNICAL BULLETIN: SARS-COV-2 MUTATION ANALYSIS AND INVESTIGATION

Posted on Thu, Oct 14, 2021 @ 05:01 PM

Updated : Thu, October 14, 2021 @ 10:01 PM

SARS-CoV-2 mutations and associated new variants are being reported...

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qPCR


8 QPCR AMPLIFICATION PLOT QUESTIONS ANSWERED

Posted on Thu, Sep 30, 2021 @ 10:00 AM

Updated : Thu, February 3, 2022 @ 6:10 PM

When results from your qPCR assays aren’t quite what you expected, it can be...

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Molecular diagnostics qPCR SARS-CoV-2


CAN COVID-19 TESTING BE MADE MORE SUSTAINABLE DURING PROLONGED UNCERTAINTY?

Posted on Mon, Sep 27, 2021 @ 02:36 PM

UPDATED : THU, MARCH 31, 2022 @ 3:24 PM

In September 2021, Delta persists as the most prevalent variant worldwide1
due...

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Molecular diagnostics


THE SURPRISING GLOBAL IMPACTS OF EUROPE'S IN VITRO DIAGNOSTIC REGULATION (IVDR)

Posted on Thu, Sep 16, 2021 @ 12:15 PM

UPDATED : WED, SEPTEMBER 15, 2021 @ 4:40 AM

A SHORTCUT TO UNDERSTANDING HOW TO PREPARE FOR IVDR

In today’s global...

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Oligo synthesis and modifications


OLIGONUCLEOTIDE SYNTHESIS BASICS: INTRODUCTION TO PHOSPHORAMIDITE CHEMISTRY

Posted on Tue, Sep 14, 2021 @ 02:00 PM

UPDATED : WED, DECEMBER 14, 2022 @ 4:43 PM

This is the first blog post in a three-part educational series about best...

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Agrigenomics PCR-based genotyping Nucleic acid extraction


4 STEPS TO OPTIMISE SAMPLE COLLECTION FOR AQUACULTURE GENOTYPING

Posted on Tue, Sep 07, 2021 @ 02:59 PM

Updated : Tue, September 7, 2021 @ 7:59 PM

Aquaculture breeding programmes adopt genomic technologies, including...

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Molecular diagnostics SARS-CoV-2


TIPS FOR EARLY-STAGE MDX COMPANIES LAUNCHING NEW TESTS DURING COVID-19 TIMES

Posted on Thu, Sep 02, 2021 @ 02:00 PM

UPDATED : WED, NOVEMBER 9, 2022 @ 8:20 PM

The COVID-19 pandemic brought tremendous change to the molecular diagnostics...

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SARS-CoV-2


WASTEWATER SURVEILLANCE: A CRITICAL TOOL IN PANDEMIC MANAGEMENT

Posted on Tue, Aug 31, 2021 @ 09:48 AM

Updated : Thu, September 29, 2022 @ 7:57 PM

As SARS-CoV-2 variants continue to threaten public health, officials are...

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SARS-CoV-2


TECHNICAL BULLETIN: EMERGING SARS-COV-2 MUTATIONS AND THEIR EFFECT ON THE IMMUNE
RESPONSE

Posted on Wed, Aug 18, 2021 @ 03:45 PM

UPDATED : THU, DECEMBER 16, 2021 @ 6:46 PM

Emerging SARS-CoV-2 variants of concern and variants of interest are defined...

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Agrigenomics Next generation sequencing (NGS) Nucleic acid extraction


THE IMPORTANCE OF SAMPLE PROCESSING FOR SUCCESSFUL PLANT GENOTYPING BY NGS

Posted on Thu, Aug 12, 2021 @ 06:51 PM

UPDATED : THU, AUGUST 12, 2021 @ 11:51 PM

Informed plant breeding decisions help drive the field of agrigenomics...

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Agrigenomics Nucleic acid extraction


DON'T UNDERESTIMATE THE COMPLEXITY OF YOUR SAMPLE COMPOSITION

Posted on Wed, Aug 04, 2021 @ 04:34 PM

UPDATED : WED, AUGUST 4, 2021 @ 9:34 PM

A common mistake when initiating an agrigenomics project is failing to
consider...

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Agrigenomics Genomics


SELECTIVE BREEDING IN AQUACULTURE: ADVANCING BREEDING PROGRAMMES THROUGH
GENOMICS

Posted on Wed, Jun 09, 2021 @ 11:15 AM

Updated : Wed, December 14, 2022 @ 1:44 PM

The global demand for fish and fish products continues to increase as...

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Molecular diagnostics Genomics SARS-CoV-2


GENOMIC SURVEILLANCE: 3 TECHNIQUES TO DETECT AND CHARACTERISE SARS-COV-2
VARIANTS

Posted on Wed, May 19, 2021 @ 11:34 AM

UPDATED : THU, MARCH 9, 2023 @ 5:37 PM

As the global population gains greater access to vaccines for COVID-19,...

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Molecular diagnostics SARS-CoV-2


HOW DO SARS-COV-2 VARIANTS AFFECT PCR ASSAYS FOR COVID-19 TESTING?

Posted on Tue, May 04, 2021 @ 11:03 AM

UPDATED : THU, MARCH 9, 2023 @ 5:34 PM

Researchers have identified several variants of SARS-CoV-2 since they
sequenced...

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Agrigenomics Genomics NGS-based genotyping


BEST PRACTICES FOR IMPLEMENTING TARGETED GENOTYPING BY SEQUENCING

Posted on Wed, Dec 02, 2020 @ 10:53 AM

UPDATED : FRI, NOVEMBER 20, 2020 @ 5:16 PM

In breeding programmes, selections based on a single or small number of...

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Molecular diagnostics Genomics SARS-CoV-2


BUILDING RESILIENCE INTO SARS-COV-2 TESTING WORKFLOWS: CONSIDERATIONS FOR
CHOOSING AN RNA ISOLATION METHOD

Posted on Wed, Oct 21, 2020 @ 11:00 AM

UPDATED : THU, FEBRUARY 3, 2022 @ 4:39 PM

Clinical and diagnostic labs worldwide are still experiencing supply chain...

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Genomics PCR-based genotyping


HOW HIGH-THROUGHPUT GENOTYPING AUTOMATION AND KASP MARKER LIBRARIES CONNECT
RESEARCH LABS WITH COMMERCIAL BREEDERS TO ACCELERATE CROP IMPROVEMENT

Posted on Wed, Oct 07, 2020 @ 11:31 AM

UPDATED : WED, OCTOBER 7, 2020 @ 4:33 PM

“In July of 2015, I was a member of the radish genome project team. My task...

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Agrigenomics Genomics PCR-based genotyping


EMPLOYEE SPOTLIGHT: MEET DARSHNA "DUSTY" VYAS

Posted on Mon, Sep 14, 2020 @ 10:15 AM

UPDATED : FRI, SEPTEMBER 11, 2020 @ 9:52 PM

Darshna "Dusty" Vyas has been a Senior Scientist at LGC specialising in...

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Molecular diagnostics Genomics SARS-CoV-2


PRESSING COVID-19 TESTING ISSUES OF TODAY AND THE NEAR FUTURE

Posted on Wed, Aug 26, 2020 @ 09:57 AM


UPDATED : TUE, OCTOBER 6, 2020 @ 6:45 PM


FOLLOWING UP WITH THE PANELISTS FROM OUR RECENT COVID-19 WEBINAR, PART 3 OF 3

...

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Molecular diagnostics Genomics SARS-CoV-2


SENSITIVITY AND ACCURACY IN COVID-19 TESTING

Posted on Wed, Aug 19, 2020 @ 09:56 AM


UPDATED : TUE, OCTOBER 6, 2020 @ 6:42 PM


FOLLOWING UP WITH THE PANELISTS FROM OUR RECENT COVID-19 WEBINAR, PART 2 OF 3

...

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Molecular diagnostics Genomics SARS-CoV-2


SCALING UP COVID-19 VIRAL TESTING

Posted on Wed, Aug 12, 2020 @ 09:47 AM


UPDATED : TUE, OCTOBER 6, 2020 @ 6:45 PM


FOLLOWING UP WITH THE PANELISTS FROM OUR RECENT COVID-19 WEBINAR, PART 1 OF 3

...

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Molecular diagnostics Genomics qPCR SARS-CoV-2


ENABLING A RAPID RESPONSE TO COVID-19 BY HONEYWELL AND LGC, BIOSEARCH
TECHNOLOGIES

Posted on Wed, Jul 29, 2020 @ 02:40 PM

UPDATED : TUE, OCTOBER 6, 2020 @ 6:44 PM

As countries worldwide begin to ease lockdown restrictions during the
pandemic...

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Agrigenomics Genomics PCR-based genotyping


ESTABLISHMENT OF KASP MARKER LIBRARY FOR GENETIC DIVERSITY ANALYSIS IN BRASSICA
RAPA  CROPS

Posted on Tue, Jul 14, 2020 @ 10:17 AM

Updated : Tue, July 14, 2020 @ 1:30 PM

Brassica  rapa crops are important sources of food, feed, and fuel in many
parts...

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Molecular diagnostics Genomics qPCR SARS-CoV-2


ROBUST SUPPLY CHAINS AND OPEN TESTING SYSTEMS: HOW OUR AGBIO ROOTS MEET THE
FDA'S EUA PROCESS TO ENABLE SOLUTIONS TO THE COVID-19 PANDEMIC

Posted on Tue, May 19, 2020 @ 10:18 AM

Updated : Fri, December 18, 2020 @ 8:49 PM

It may seem strange that a company known for transforming the global seed...

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Molecular diagnostics Oligo synthesis and modifications Genomics SARS-CoV-2


BEHIND THE SCENES: HOW OUR OLIGO SYNTHESIS TEAM CONTRIBUTES TO THE RELIABILITY
OF YOUR ASSAYS

Posted on Thu, Apr 30, 2020 @ 04:13 PM


UPDATED : WED, MARCH 22, 2023 @ 1:52 PM


WE’RE NOT REJECTING YOU, JUST YOUR OLIGO

PCR is arguably one of the most...

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Molecular diagnostics SARS-CoV-2


WHEN YOU DON’T NEED AN EUA FOR SARS-COV-2 TESTING

Posted on Fri, Apr 10, 2020 @ 05:00 PM

UPDATED : WED, NOVEMBER 25, 2020 @ 8:23 PM

On March 25, 2020, the US Food and Drug Administration (FDA) held the first...

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Genomics Next generation sequencing (NGS) NGS-based genotyping


NEW NGS SERVICE LAB NOW OPEN IN MIDDLETON, WI FOR EXPANDED GLOBAL SUPPORT

Posted on Wed, Apr 01, 2020 @ 11:27 AM

UPDATED : WED, APRIL 1, 2020 @ 8:12 PM

Back in September 2018, LGC acquired Lucigen Corporation. The ISO accredited...

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Molecular diagnostics Oligo synthesis and modifications Genomics SARS-CoV-2


ADDRESSING COVID-19 TOGETHER: LGC, BIOSEARCH TECHNOLOGIES AND SHANGHAI LIFERIVER
BIOTECHNOLOGY CO., LTD.

Posted on Tue, Mar 31, 2020 @ 12:13 PM

Updated : Tue, October 6, 2020 @ 6:44 PM

In the nearly three months since the first confirmed case of COVID-19, the...

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Molecular diagnostics Genomics SARS-CoV-2


WHAT DIAGNOSTIC TEST MAKERS AND CLIA LABS IN THE US NEED TO KNOW ABOUT EMERGENCY
USE AUTHORIZATION (EUA)

Posted on Tue, Mar 24, 2020 @ 01:58 PM

Updated : Tue, March 21, 2023 @ 3:41 PM

*Since the original publication of this blog, LGC Biosearch Technologies is
now...

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Molecular diagnostics Genomics SARS-CoV-2


CORONAVIRUS OUTBREAK: COLLABORATION TO MEET THE CHALLENGE

Posted on Mon, Mar 16, 2020 @ 02:30 PM

{% video_player "embed_player" overrideable=False, type='scriptV4',
hide_playlist=True, viral_sharing=False,...
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Molecular diagnostics Next generation sequencing (NGS)


MOLECULAR DIAGNOSTICS: HOW CAN NGS LIVE UP TO ITS PROMISES?

Posted on Wed, Jan 29, 2020 @ 11:37 AM

UPDATED : TUE, OCTOBER 11, 2022 @ 8:43 PM

The development of new genomic sequencing techniques and bioinformatics...

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Genomics PCR-based genotyping NGS-based genotyping


BACK TO BASICS - THE CRUCIAL STEP OF SAMPLE COLLECTION

Posted on Wed, Jan 15, 2020 @ 11:37 AM


UPDATED : MON, JANUARY 13, 2020 @ 5:08 PM


BEST PRACTICE IN SAMPLE COLLECTION FOR SEQSNP TARGETED GENOTYPING BY...

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Agrigenomics Genomics Next generation sequencing (NGS) NGS-based genotyping


GENOMIC SELECTION: CAN IT ACCELERATE LIVESTOCK BREEDING?

Posted on Wed, May 01, 2019 @ 10:44 AM

UPDATED : WED, MAY 1, 2019 @ 3:59 PM

Livestock supports the livelihoods and food security of almost 1.3 billion
people...

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Genomics


THE WOMEN OF LGC, BIOSEARCH TECHNOLOGIES

Posted on Fri, Mar 29, 2019 @ 11:24 AM

UPDATED : FRI, MARCH 29, 2019 @ 4:39 PM

We've heard it said for years, "TV will rot your brain". But in the case of
our...

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Agrigenomics PCR-based genotyping Next generation sequencing (NGS) NGS-based
genotyping


AGRIGENOMICS: HOW CAN NGS CONTRIBUTE TO GLOBAL FOOD SECURITY?

Posted on Wed, Mar 06, 2019 @ 10:33 AM

UPDATED : FRI, MAY 19, 2023 @ 8:53 AM

“Experience of artificial fertilisation, such as is effected with ornamental...

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Agrigenomics Next generation sequencing (NGS) NGS-based genotyping


HOW TARGETED GBS-DRIVEN GENOMIC SELECTION CAN HELP YOU GET TO MARKET FASTER

Posted on Wed, Jan 16, 2019 @ 01:22 PM

UPDATED : THU, MAY 25, 2023 @ 11:32 AM

Plant and animal breeding programmes often take generations to improve
quality...

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Genomics NGS-based genotyping


GENOMIC SELECTION: METHODS IN CROP AND ANIMAL BREEDING

Posted on Wed, Jan 09, 2019 @ 10:48 AM

UPDATED : WED, JANUARY 9, 2019 @ 5:03 PM

Genomic selection: 6 factors to consider when choosing between targeted GBS...

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Agrigenomics Next generation sequencing (NGS) NGS-based genotyping


OUR HUNGRY PLANET: NEW TOOLS IN AGRIGENOMICS ARE KEY TO FOOD SECURITY

Posted on Tue, Dec 11, 2018 @ 10:32 AM

UPDATED : TUE, DECEMBER 11, 2018 @ 4:32 PM

Food security is a major global threat and traditional methods of plant and...

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PCR-based genotyping


ACCELERATING RICE IMPROVEMENT IN SOUTH ASIA

Posted on Thu, Jul 26, 2018 @ 11:26 AM

Updated : Thu, July 26, 2018 @ 4:41 PM

Diversity is the spice of life and is also key to breeding rice that delivers...

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Genomics


REVOLUTIONISING CANCER TREATMENT ONE ARRAY AT A TIME

Posted on Tue, Jul 10, 2018 @ 11:05 AM

UPDATED : MON, SEPTEMBER 19, 2022 @ 2:14 PM

While the science of pharmacogenomics has been around for years, its...

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Genomics Nucleic acid extraction


PACK IT UP, PACK IT IN, LET ME BEGIN: A LOOK AT THE FUTURE OF DNA DATA STORAGE

Posted on Thu, Jun 28, 2018 @ 11:13 AM

UPDATED : THU, JUNE 28, 2018 @ 4:28 PM

Imagine a time capsule the size of a shoebox that holds all the information...

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RNA FISH Genomics


WARNING! PITFALLS AHEAD: HOW TO AVOID THE MOST COMMON STELLARIS RNA FISH
MISTAKES

Posted on Tue, May 29, 2018 @ 10:32 AM

UPDATED : TUE, MAY 29, 2018 @ 3:47 PM

Ever wake up in the morning just feeling like a rock star, or maybe like
Francis...

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RNA FISH Genomics


SHINING A LIGHT ON GENE EXPRESSION AND REGULATION ONE CELL AT A TIME

Posted on Thu, Apr 19, 2018 @ 12:51 PM

UPDATED : MON, APRIL 30, 2018 @ 1:53 PM

To truly understand complex diseases such as cancer, scientists need access
to...

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Genomics


THE WOMEN OF LGC

Posted on Thu, Mar 29, 2018 @ 10:45 AM

UPDATED : THU, MARCH 29, 2018 @ 4:00 PM

Ask any little girl what they want to be when they grow up and you may hear...

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RNA FISH Genomics


IN CASE YOU MISSED IT: STELLARIS RNA FISH LUNCH-AND-LEARN

Posted on Tue, Jan 16, 2018 @ 10:35 AM

UPDATED : TUE, JANUARY 16, 2018 @ 4:50 PM

Stellaris® RNA FISH (fluorescence in situ hybridization) is an RNA...

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Agrigenomics Genomics NGS-based genotyping


TACKLING FOOD CRISIS THROUGH COST EFFECTIVE, TARGET ENRICHED SEQUENCING

Posted on Wed, Dec 13, 2017 @ 10:07 AM

UPDATED : MON, SEPTEMBER 19, 2022 @ 2:16 PM

With the global population predicted to reach 9 billion people within the...

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Agrigenomics Genomics PCR-based genotyping


NEW SNPS IDENTIFIED IN THE HUNT FOR NEW GENETIC WEAPONS TARGETING LEAF RUST IN
WHEAT

Posted on Tue, Nov 21, 2017 @ 11:25 AM

UPDATED : WED, NOVEMBER 22, 2017 @ 1:44 PM

Wheat is one of the three most important crops for human and livestock feed....

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Agrigenomics Genomics PCR-based genotyping


SUPER-CROPS HELPING TO FEED AFRICA

Posted on Fri, Nov 03, 2017 @ 11:08 AM

UPDATED : TUE, JULY 10, 2018 @ 9:08 PM

Our world population is growing at a tremendous rate and by 2050, Africa’s...

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Genomics PCR-based genotyping Disease detection


HOW GENOTYPING IS AIDING IN THE FIGHT AGAINST MALARIA

Posted on Wed, Sep 20, 2017 @ 10:11 AM

Updated : Mon, September 19, 2022 @ 2:14 PM

3.2 billion people across 106 countries and territories, live in areas at...

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RNA FISH Genomics


LUNCH & LEARN: STELLARIS RNA FISH

Posted on Thu, Jul 06, 2017 @ 10:07 AM

UPDATED : THU, JULY 6, 2017 @ 3:22 PM

Recently LGC Genomics hosted a lunch and learn Stellaris® seminar at the
Helen...

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Genomics qPCR


IT’S OFFICIAL! PERSONAL HEALTH BECOMES FIRST CHINA DEMONSTRATION LABORATORY SITE
FOR LGC’S NEXAR SYSTEM

Posted on Wed, May 03, 2017 @ 09:05 AM

Updated : Mon, September 19, 2022 @ 2:07 PM

LGC's Genomics Division has signed a memorandum of understanding (MOU) with...

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qPCR


DIGITAL PCR – IMPROVING REPRODUCIBLE MOLECULAR METHODS IN THE CLINIC

Posted on Thu, Apr 06, 2017 @ 10:40 AM

UPDATED : THU, APRIL 6, 2017 @ 3:40 PM

A recent study coordinated by LGC and published in the journal Analytical...

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RNA FISH Disease detection


SHINING A LIGHT ON HOW ZIKA VIRUS MAY SPREAD FROM MOTHERS TO HUMAN FETUSES

Posted on Mon, Mar 06, 2017 @ 10:37 AM

UPDATED : MON, MARCH 6, 2017 @ 4:37 PM

New research has, for the first time, found evidence suggesting the molecular...

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WATER – BACK TO BASICS FOR THERMAL CYCLING

Posted on Tue, Feb 28, 2017 @ 10:13 AM

UPDATED : MON, SEPTEMBER 19, 2022 @ 2:20 PM

It’s time to forget what you know about heating your PCR plates for...

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Genomics PCR-based genotyping


OVERCOMING DROUGHT-INTOLERANCE IN MAIZE TO FEED THE GROWING ASIAN POPULATION

Posted on Wed, Feb 15, 2017 @ 09:53 AM

UPDATED : WED, FEBRUARY 15, 2017 @ 4:23 PM

Demand for maize is increasing due to an increased number of people...

Read more

Genomics


AUTOMATE TO ACCELERATE AND SCALE-UP SNP-BASED GENOTYPING WORKFLOWS!

Posted on Thu, Feb 02, 2017 @ 09:14 AM

UPDATED : MON, SEPTEMBER 19, 2022 @ 2:05 PM

The advent of and ongoing improvements to next-generation sequencing...

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Genomics


MULTIPLE MISUNDERSTANDINGS: LEARNING FROM GENETIC DETERMINISM

Posted on Mon, Jan 23, 2017 @ 10:12 AM

UPDATED : MON, JANUARY 23, 2017 @ 4:27 PM

Nature versus nurture. It’s a tale as old as time.

When Craig Venter made the...

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Agrigenomics Genomics PCR-based genotyping NGS-based genotyping


HELPING TO FEED THE WORLD WITH GENOTYPING BY SEQUENCING

Posted on Tue, Jan 17, 2017 @ 09:42 PM

UPDATED : WED, JANUARY 18, 2017 @ 2:13 PM

Many areas critical to improved agricultural production require robust and...

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PCR-based genotyping


FASTER, STRONGER, QUICKER: SSR TO KASP WILL GET YOU THERE

Posted on Mon, Jan 09, 2017 @ 09:05 AM

UPDATED : MON, JANUARY 9, 2017 @ 3:20 PM

Screen more markers faster and bring crops with superior traits to the market...

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Genomics qPCR


MULTIPLEX YOUR QPCR AND WALK-AWAY

Posted on Thu, Dec 15, 2016 @ 10:17 AM

UPDATED : MON, SEPTEMBER 19, 2022 @ 2:15 PM

It seems everyone wants to do more with less, and automate the process as...

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RNA FISH Genomics


A STELLAR-IS YEAR IN THE MAKING

Posted on Wed, Dec 07, 2016 @ 10:05 AM

UPDATED : MON, SEPTEMBER 19, 2022 @ 2:12 PM 

It wouldn't be fair to close out 2016 without showcasing the stellar year...

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Genomics


BUDDY UP: THE DOUBLE HELIX

Posted on Mon, Nov 28, 2016 @ 09:15 AM

UPDATED : MON, NOVEMBER 28, 2016 @ 11:31 PM

The secret of life. That’s what Francis Crick and James Watson claimed they...

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Genomics


GENES, PROTEINS & DNA: OUR HEREDITARY SOFTWARE

Posted on Mon, Nov 21, 2016 @ 09:17 AM

UPDATED : MON, NOVEMBER 21, 2016 @ 3:32 PM

In the early 1900s, scientists found that the function of genes was to make...

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Genomics


"X" MARKS THE SPOT: A CLOSER LOOK AT CHROMOSOMES

Posted on Mon, Nov 14, 2016 @ 09:28 AM

UPDATED : WED, MARCH 29, 2023 @ 10:51 AM

The strands of DNA in your cells are organized into pieces called
chromosomes....

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Genomics


EXCEL AUTOCORRECT FAILS THE GENOMICS COMMUNITY - ARE YOUR RESULTS EXCELLENT OR
EXCEL-NOT?

Posted on Thu, Sep 08, 2016 @ 11:30 AM

UPDATED : MON, SEPTEMBER 19, 2022 @ 2:13 PM

Researchers from the Baker IDI Heart and Diabetes Institute in Melbourne,...

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qPCR


QPCR-BASED MOLECULAR DIAGNOSTICS AT THE FOREFRONT OF ZIKA SURVEILLANCE

Posted on Tue, Aug 23, 2016 @ 04:00 PM

UPDATED : WED, MARCH 29, 2023 @ 11:04 AM

As the Zika virus outbreak spreads, a wave of international concern has
grown,...

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Oligo synthesis and modifications


KNOW YOUR OLIGO MOD: THIO C6 LINKER

Posted on Thu, Jul 14, 2016 @ 04:00 PM

UPDATED : WED, MARCH 29, 2023 @ 10:55 AM


THIO C6 LINKER (THIOHEXYL) 

We continue our “Know Your Oligo Mod” series with...

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Agrigenomics


A COMPLETE ECOSYSTEM TO ACCELERATE BREEDING PROGRAMS [INFOGRAPHIC]

Posted on Tue, Jun 28, 2016 @ 04:00 PM

UPDATED : TUE, JUNE 28, 2016 @ 9:00 PM

Modern breeding methods rely on the identification and utilization of
molecular...

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Molecular diagnostics Oligo synthesis and modifications qPCR


PHOTOBLOG: BEHIND THE SCENES OF OLIGO SYNTHESIS

Posted on Wed, May 18, 2016 @ 05:00 PM

UPDATED : WED, DECEMBER 14, 2022 @ 5:04 PM

OLIGO SYNTHESIS PHOTO GLIMPSE

We’ve recently captured our talented...

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qPCR


NOVA IS THE NEW BLACK

Posted on Thu, Apr 14, 2016 @ 04:00 PM

Updated : Mon, April 24, 2023 @ 8:54 AM

LGC Biosearch Technologies has developed a new qPCR probe format powered by...

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LEARN ABOUT THE LATEST DEVELOPMENTS IN TECHNOLOGIES FOR MOLECULAR BREEDING
PROGRAMS

Posted on Thu, Mar 31, 2016 @ 04:00 PM

UPDATED : THU, MARCH 31, 2016 @ 9:01 PM

At this year’s 24th annual Plant & Animal Genome (PAG) conference, LGC...

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RNA FISH


IMAGING STELLARIS ASSAYS PART III: CREATING PROFESSIONAL, PUBLICATION-READY
IMAGES

Posted on Thu, Mar 10, 2016 @ 04:00 PM

Updated : Wed, August 16, 2017 @ 9:15 AM

Here is the final installment of our “Imaging Stellaris Assays” blog series....

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RNA FISH


DESIGNING STELLARIS RNA FISH PROBES PART I: INCREASING PROBE COUNT

Posted on Thu, Jan 14, 2016 @ 04:00 PM

Updated : Tue, September 27, 2022 @ 2:32 PM

Stellaris® RNA FISH is a novel technology that allows for the detection of...

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Oligo synthesis and modifications qPCR


KNOW YOUR OLIGO MOD: 3' SPACER C3

Posted on Thu, Oct 15, 2015 @ 04:15 PM

UPDATED : WED, MARCH 29, 2023 @ 10:54 AM

This week, we continue our Know your oligo mod blog series and we will focus...

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RNA FISH


IMAGING STELLARIS ASSAYS PART II: HOW TO ACQUIRE STUNNING IMAGES

Posted on Thu, Sep 24, 2015 @ 04:30 PM

UPDATED : WED, AUGUST 16, 2017 @ 9:13 AM

Here we continue our “Imaging Stellaris Assays” blog series. We last left off...

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RNA FISH


RUNAWAY RNA STAYS PUT

Posted on Thu, Sep 17, 2015 @ 04:00 PM

UPDATED : TUE, MARCH 21, 2023 @ 3:53 PM

The cleavage and polyadenylation event, the final trimming in the molecular...

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RNA FISH


IMAGING STELLARIS ASSAYS PART I: GET TO KNOW YOUR MICROSCOPE

Posted on Thu, Aug 27, 2015 @ 07:00 PM

UPDATED : WED, AUGUST 16, 2017 @ 9:42 PM

Stellaris® FISH is an RNA detection technology performed by means of in situ...

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Oligo synthesis and modifications


THE AGCT’S OF DNA SYNTHESIS

Posted on Tue, Aug 11, 2015 @ 04:00 PM

UPDATED : WED, MARCH 29, 2023 @ 10:38 AM

Chemically synthesized DNA has become an indispensable tool for molecular...

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Oligo synthesis and modifications


KNOW YOUR OLIGO MOD: BHQ® (BLACK HOLE QUENCHER®) NON-FLUORESCENT QUENCHERS

Posted on Thu, Jul 23, 2015 @ 04:00 PM

UPDATED : FRI, JANUARY 13, 2023 @ 11:35 AM

In this instalment, we will cover the basics of LGC Biosearch Technologies’...

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RNA FISH qPCR


AND THE CONSENSUS (SEQUENCE) IS...

Posted on Thu, Jun 11, 2015 @ 04:31 PM

UPDATED : FRI, NOVEMBER 13, 2015 @ 9:25 PM

Studying the expression level of RNA transcripts is often complicated by the...

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RNA FISH


RESEARCH HIGHLIGHT: BRINGING VISION RESEARCH INTO FOCUS

Posted on Thu, May 28, 2015 @ 04:14 PM

UPDATED : TUE, MARCH 21, 2023 @ 3:37 PM

Gene expression and molecular biology research in vision and ophthalmology...

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RNA FISH


FISH-ING FOR FUSIONS: A UNIQUE APPROACH TO FUSION GENE MRNA & PRE-MRNA DETECTION
IN CANCER

Posted on Fri, May 15, 2015 @ 03:00 PM

UPDATED : FRI, NOVEMBER 13, 2015 @ 10:27 PM

This past April, Biosearch attended the American Association of Cancer...

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qPCR


HOW MUCH IS YOUR QPCR ASSAY REALLY COSTING YOU?

Posted on Thu, Apr 02, 2015 @ 04:00 PM

UPDATED : FRI, NOVEMBER 13, 2015 @ 10:40 PM

In the setup of a qPCR experiment, one of the first decisions to make is...

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RNA FISH


THE 4CS OF STELLARIS® RNA FISH BUFFERS

Posted on Thu, Feb 26, 2015 @ 04:00 PM

UPDATED : MON, NOVEMBER 16, 2015 @ 3:55 PM 

Buffers are often overlooked and taken for granted until the day comes when...

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Oligo synthesis and modifications


KNOW YOUR OLIGO MOD: PHOSPHOROTHIOATE BONDS

Posted on Thu, Feb 12, 2015 @ 04:00 PM

UPDATED : WED, MARCH 29, 2023 @ 10:56 AM

This post in our continuing series, “Know your oligo mod” will cover ...

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qPCR


OPTIMISING MULTIPLEX COMPETITIVE QRT-PCR IN DIAGNOSTICS WITH BHQPLUS PROBES

Posted on Thu, Jan 29, 2015 @ 04:00 PM

UPDATED : MON, NOVEMBER 16, 2015 @ 5:30 PM

In a webinar linked below, Dr. James Willey describes a two colour...

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qPCR PCR-based genotyping


A SUCCESSFUL DUO FOR ACCURATE, SPEEDY, AND ECONOMICAL SNP GENOTYPING

Posted on Thu, Jan 08, 2015 @ 01:30 PM

UPDATED : MON, SEPTEMBER 19, 2022 @ 2:12 PM

Single Nucleotide Polymorphisms (SNPs) have been widely studied for over 15...

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Oligo synthesis and modifications


KNOW YOUR OLIGO MOD: METHYLENE BLUE

Posted on Tue, Dec 09, 2014 @ 04:02 PM

UPDATED : WED, MARCH 29, 2023 @ 10:56 AM

The chemical synthesis of oligonucleotides allows for the incorporation of a...

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RNA FISH


UNRAVELING THE NEURAL WEB: STELLARIS® RNA FISH FOR NEUROSCIENCE RESEARCH

Posted on Thu, Nov 13, 2014 @ 05:45 PM

UPDATED : MON, SEPTEMBER 19, 2022 @ 2:14 PM

Neuroscience gene expression research can come with many hurdles,...

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qPCR


CHECK OUT OUR NEW WEBSITE QPCR DESIGN LAB @ QPCRDESIGN.COM

Posted on Thu, Oct 23, 2014 @ 04:00 PM

UPDATED : TUE, MARCH 28, 2023 @ 9:02 PM

Biosearch Technologies has launched qPCRdesign.com, a microsite targeted...

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Oligo synthesis and modifications qPCR


DELIVERING OLIGOS BY NANOMOLE UNITS

Posted on Wed, Oct 15, 2014 @ 01:00 PM

UPDATED : TUE, OCTOBER 14, 2014 @ 10:21 PM

Different oligonucleotide manufacturers deliver probes and primers in a...

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Molecular diagnostics qPCR


RT-QPCR MOLECULAR DIAGNOSTICS ASSIST WORKERS AT THE FOREFRONT OF EBOLA OUTBREAK.

Posted on Thu, Sep 25, 2014 @ 01:30 PM

UPDATED : MON, SEPTEMBER 19, 2022 @ 2:13 PM

The largest recorded Ebola Virus Disease outbreak in history continues to...

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qPCR


ONE STEP TOO MANY? SIMPLIFY YOUR QPCR PROTOCOL

Posted on Thu, Feb 27, 2014 @ 12:02 PM

UPDATED : MON, SEPTEMBER 19, 2022 @ 2:12 PM

Don’t waste time performing an extra step. Cut back on pipetting and order...

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qPCR


30 YEARS: THE IMPACT OF PCR

Posted on Thu, Sep 05, 2013 @ 11:29 AM

UPDATED : TUE, MARCH 21, 2023 @ 3:52 PM

Do you remember when the most popular method of DNA amplification involved...

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RNA FISH qPCR


RT-QPCR AND THE STELLARIS FISH METHOD

Posted on Fri, Apr 26, 2013 @ 12:32 PM

UPDATED : MON, SEPTEMBER 19, 2022 @ 2:10 PM

A "Referral from the Doctor" Blog Article-

Quantitative reverse...

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BIOSEARCH TECHNOLOGIES RESPONDS TO CHINA INFLUENZA H7N9 OUTBREAK BY PROVIDING
H7N9 DETECTION PANEL

Posted on Mon, Apr 15, 2013 @ 08:00 AM

UPDATED : MON, SEPTEMBER 19, 2022 @ 2:13 PM

Biosearch Technologies, Inc. (Biosearch) announced today that the company...

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RNA FISH


STELLARIS® FOUNDATION GENES: GAPDH

Posted on Thu, Apr 11, 2013 @ 11:30 AM

UPDATED : WED, OCTOBER 1, 2014 @ 4:53 PM

Stellaris probe sets targeting glyceraldehyde-3-phosphate dehydrogenase...

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RNA FISH


BIOSEARCH TECHNOLOGIES, UMDNJ STELLARIS® PROBE ALLIANCE - NEXTGEN GENE
EXPRESSION™, SNP FISH™, AND ICEFISH™ IN RESEARCH AND CLINICAL APPLICATIONS

Posted on Mon, Mar 18, 2013 @ 10:43 AM

UPDATED : MON, SEPTEMBER 19, 2022 @ 2:07 PM

Biosearch Technologies, Inc. (Biosearch), a leading supplier of...

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BIOSEARCH TECHNOLOGIES ANNOUNCES ACQUISITION OF EUROPEAN COMPANIES DNA
TECHNOLOGY AND VITRABIO

Posted on Thu, Feb 21, 2013 @ 08:00 AM

UPDATED : WED, OCTOBER 1, 2014 @ 4:53 PM

Biosearch Technologies, Inc. (Biosearch), a leading supplier of...

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RNA FISH


BIOSEARCH TECHNOLOGIES LAUNCHES CATALOGUED STELLARIS™ RNA FISH ASSAYS

Posted on Mon, Jun 18, 2012 @ 10:08 AM

UPDATED : MON, SEPTEMBER 19, 2022 @ 2:07 PM

Biosearch Technologies, Inc. (Biosearch), a leading supplier of...

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RNA FISH


SINGLE MOLECULE VIRAL RNA ANALYSIS USING STELLARIS™ FISH TECHNOLOGY

Posted on Wed, May 30, 2012 @ 03:00 PM

  IMAGE COURTESY OF: HTTP://WWW.CDC.GOV/H1N1FLU/IMAGES.HTM

UPDATED : MON, SEPTEMBER 19, 2022 @ 2:13 PM

A...

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Molecular diagnostics qPCR


QPCR PROBES AT WORK: INNOVATIVE CLIA TEST FOR NSCLC STAGING

Posted on Tue, Mar 06, 2012 @ 01:00 PM

UPDATED : WED, OCTOBER 1, 2014 @ 4:51 PM

Non-squamous, Non-small cell lung cancer (NSCLC), the most common cause of...

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qPCR


FACTORS AFFECTING FLUOROPHORE PERFORMANCE IN QPCR

Posted on Wed, Jan 11, 2012 @ 11:00 AM

UPDATED : FRI, OCTOBER 21, 2022 @ 10:24 AM

Fluorophores are molecules that can absorb light energy in a process called...

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THE 'MONTE CARLO' EFFECT IN QPCR

Posted on Wed, Nov 09, 2011 @ 01:00 PM

UPDATED : MON, SEPTEMBER 19, 2022 @ 2:10 PM

A "Referral from the Doctor" Blog Article-

The mathematical model of PCR...

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qPCR


FLUORESCENCE QUENCHING MECHANISMS FOR DUAL-LABELED PROBES

Posted on Wed, Jun 29, 2011 @ 09:44 AM

UPDATED : MON, SEPTEMBER 19, 2022 @ 2:10 PM

A "Referral from the Doctor" Blog Article-

Fluorescent probes are used in...

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qPCR


MULTIPLEXING WITH XANTHENES

Posted on Wed, Jun 08, 2011 @ 11:13 AM

UPDATED : MON, SEPTEMBER 19, 2022 @ 2:10 PM

A "Referral from the Doctor" Blog Article-

Quantitative real-time PCR...

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qPCR


QPCR TROUBLESHOOTING: INTERPRETING AMPLIFICATION CURVES AND DIAGNOSING PROBLEMS

Posted on Thu, May 05, 2011 @ 12:15 PM

UPDATED : THU, MAY 11, 2023 @ 10:06 AM

If you run quantitative real-time PCR (qPCR) assays, the chances are that...

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qPCR


BETWEEN ROX AND A HARD PLACE

Posted on Wed, Nov 10, 2010 @ 11:12 AM

UPDATED : MON, SEPTEMBER 19, 2022 @ 2:10 PM

A "Referral from the Doctor" Blog Article-

ROX in qPCR

Quantitative...

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Molecular diagnostics


VISIT BIOSEARCH AT IVD TECHNOLOGY'S VIRTUAL CONFERENCE AND TRADESHOW

Posted on Thu, Sep 23, 2010 @ 04:32 PM

UPDATED : MON, SEPTEMBER 19, 2022 @ 2:07 PM

Biosearch Technologies is proud to sponsor the first IVD Technology...

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Molecular diagnostics


PILOTDX OLIGOS: EN ROUTE TO IVD

Posted on Thu, Jul 22, 2010 @ 10:07 AM

UPDATED : WED, OCTOBER 1, 2014 @ 4:42 PM

It can be difficult to transition a product from research to...

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qPCR


PIPETTING FOR QPCR

Posted on Wed, Jun 09, 2010 @ 10:41 AM

UPDATED : MON, SEPTEMBER 19, 2022 @ 2:14 PM

A "Referral from the Doctor" Blog Article-

Research trends in laboratories...

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qPCR


KILLER PROBES FOR QPCR: WHAT IS A SCORPIONS PRIMER?

Posted on Wed, Mar 24, 2010 @ 10:57 AM

UPDATED : THU, MARCH 23, 2023 @ 11:57 AM

Scorpions™ Primers are dual-labeled FRET probes that combine a Molecular...

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qPCR


A LIGHT IN THE STORM: WHAT IS A MOLECULAR BEACON?

Posted on Wed, Mar 10, 2010 @ 12:00 PM

UPDATED : MON, MARCH 20, 2023 @ 9:54 PM

Molecular Beacons are a special type of dual-labeled oligonucleotide probe....

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qPCR


DUAL-LABELED BHQ PROBES - PERFORMANCE TO “DYE” FOR

Posted on Wed, Feb 24, 2010 @ 12:20 PM

UPDATED : MON, SEPTEMBER 19, 2022 @ 2:10 PM

  A "Referral from the Doctor" Blog Article

A BHQ® probe is a dual-labeled...

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qPCR


THIS YEAR'S MVP (MOST VALUABLE PRACTICE): TOUCHDOWN PCR

Posted on Thu, Feb 04, 2010 @ 12:39 PM

UPDATED : MON, SEPTEMBER 19, 2022 @ 2:10 PM

A "Referral from the Doctor" Blog Article-  

The aim of the Polymerase...

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qPCR


THE GRAND BALLET: WINE AND BIOTECHNOLOGY

Posted on Wed, Jan 27, 2010 @ 01:15 PM

UPDATED : WED, OCTOBER 1, 2014 @ 4:38 PM

At the third qPCR Symposium, held November 9th -12th in Millbrae, CA, ETS...
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qPCR


ALTERNATIVE TO DNASE I HEAT INACTIVATION

Posted on Wed, Jan 13, 2010 @ 12:04 PM

UPDATED : WED, DECEMBER 14, 2022 @ 4:20 PM

A "Referral from the Doctor" Blog Article-

Genomic DNA contamination has...

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qPCR


A QUICK JUMP START TO MULTIPLEXING QPCR

Posted on Wed, Jan 06, 2010 @ 12:01 PM

UPDATED : THU, SEPTEMBER 22, 2022 @ 5:16 PM

By now, you've no doubt read about the reductions in error, cost and time...
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qPCR


SLOPE EFFICIENCY EQUALS MANAGEABLE AND CORRECTED PCR

Posted on Wed, Dec 09, 2009 @ 02:01 PM

UPDATED : MON, SEPTEMBER 19, 2022 @ 2:10 PM

A "Referral from the Doctor" Blog Article-  

ε = m.c.2 (shall I explain?...

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qPCR


BRINGING BACK A CHAMPION: COMPETITIVE QUANTITATIVE REAL-TIME RT-PCR

Posted on Wed, Nov 18, 2009 @ 10:08 AM

UPDATED : MON, SEPTEMBER 19, 2022 @ 2:10 PM

A "Referral from the Doctor" Blog Article-

Competitive qRT-PCR has become...

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Oligo synthesis and modifications qPCR


THE NEW FAVORITE REFERENCE GENE: 36B4, A.K.A. RPLP0

Posted on Wed, Oct 14, 2009 @ 10:06 AM

UPDATED : MON, SEPTEMBER 19, 2022 @ 2:10 PM

A "Referral from the Doctor" Blog Article-

Ribosomes are comprised of two...
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qPCR


WHAT GENES ARE HOT, WHAT GENES ARE NOT

Posted on Wed, Oct 07, 2009 @ 04:41 PM

UPDATED : MON, SEPTEMBER 19, 2022 @ 2:10 PM 

A "Referral from the Doctor" Blog Article-

 Top 10 Reference Genes for...

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Oligo synthesis and modifications qPCR


LABELING OLIGONUCLEOTIDES WITH INTERNAL BHQ DYES

Posted on Tue, Sep 29, 2009 @ 10:16 AM

UPDATED : FRI, JANUARY 13, 2023 @ 11:38 AM


WHEN TO USE AN INTERNAL BLACK HOLE QUENCHER (BHQ) LABEL IN A...

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Oligo synthesis and modifications qPCR


SALT-FREE PRIMER PAIR OPTION NOW AVAILABLE

Posted on Tue, Sep 22, 2009 @ 10:08 AM

UPDATED : MON, SEPTEMBER 19, 2022 @ 2:12 PM

Biosearch Technologies will now be offering the option of salt-free...
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Disease detection Nucleic acid therapeutics


WHY CIRCULAR RNA COULD BE THE NEXT REVOLUTION IN RNA THERAPEUTICS

While RNA-based therapeutics are taking the biotechnology world by storm
following the rapid development of the COVID-19 vaccines, the next generation
of...

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Oligo synthesis and modifications Nucleic acid therapeutics


SYNTHESIZING YOUR OWN OLIGONUCLEOTIDES: FAQS

Considering bringing oligo synthesis in-house? Here are some commonly asked
questions that we receive, grouped into four sections. You can jump to a
section...
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Molecular diagnostics


HOW TO DESIGN MRNA THERAPEUTICS FOR SCALABLE SUCCESS

The recent Nobel Prize awarded to Katalin Karikó and Drew Weissman underlined
the impact their breakthroughs in mRNA technology had in combating COVID-19....
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Molecular diagnostics Disease detection


THE RISE OF LAMP FOR RAPID POINT-OF-NEED TESTING

As the world scrambled to rapidly expand PCR testing capacity in 2020, it became
increasingly clear that there was a need for cheaper, simpler, quicker...

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Molecular diagnostics qPCR


MINIMISING ANTIBIOTIC DEPENDENCY FOR TREATING UTIS AND STIS

Antimicrobial resistance (AMR) across bacterial species is developing rapidly,
compounded by the improper use of antimicrobial agents that accelerates the...
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Oligo synthesis and modifications Nucleic acid therapeutics


WHAT’S THE LATEST IN ASO AND SIRNA TECHNOLOGIES?

Over the last few decades, researchers have made impressive strides in
developing methods to overcome the delivery, stability, and specificity
challenges of...

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Molecular diagnostics Nucleic acid extraction


DITCH THE SPIN COLUMNS WITHOUT COMPROMISING ON NUCLEIC ACID QUALITY

Whether you’re working with samples for PCR or sequencing, it's worth
questioning what type of extraction or purification method would work well with
your...
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Molecular diagnostics


MASTERING ASSAY SCALE-UP: 4 TIPS TO HELP AVOID THE MOST COMMON MISTAKES

UPDATED : FRI, MAY 26, 2023 @ 10:18 AM

Designing a new assay and scaling it for commercial use takes thoughtful
planning, foresight, and engagement with...

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Nucleic acid therapeutics


A KNACK FOR GETTING TO THE LIVER: GALNAC ENABLES LIVER-TARGETED OLIGONUCLEOTIDE
THERAPEUTICS

UPDATED : TUE, MAY 9, 2023 @ 11:03 AM

When it comes to oligonucleotide therapeutics, the challenge has always been how
to deliver an intact oligo to the right...

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Molecular diagnostics Oligo synthesis and modifications qPCR General science


A WAY TO SIMPLIFY DESIGN AND INTERPRETATION OF YOUR QPCR ASSAYS


UPDATED : FRI, MAY 5, 2023 @ 2:34 PM


HOW DOES A BHQ DYE CONTRIBUTE TO PRODUCING SUPERIOR DATA FROM YOUR ASSAYS?

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Oligo synthesis and modifications Nucleic acid therapeutics


WHICH CONTROLLED PORE GLASS IS RIGHT FOR YOUR THERAPEUTIC APPLICATION?

UPDATED : MON, JUNE 26, 2023 @ 10:24 AM

Oligonucleotide therapeutics have unlocked new treatment possibilities for rare
and fatal diseases often associated...

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Molecular diagnostics SARS-CoV-2 Disease detection


AMP CONFERENCE 2022: DEVELOPING A 5-MINUTE POINT-OF-CARE PCR TEST

UPDATED : TUE, MAY 9, 2023 @ 10:57 AM

We were delighted to attend the Association for Molecular Pathology (AMP) 2022
annual meeting, held in Phoenix, Arizona...

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Molecular diagnostics Oligo synthesis and modifications


WHAT’S NEXT FOR APTAMERS IN DIAGNOSTICS?

UPDATED : TUE, MAY 9, 2023 @ 11:01 AM

Originally developed in the early 1990s, aptamers have long been heralded as an
antibody alternative for detection...

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Molecular diagnostics Nucleic acid extraction General science


HOW TO SELECT AN EFFECTIVE NUCLEIC ACID ISOLATION METHOD FOR HUMAN DIAGNOSTICS?

Updated : Tue, May 9, 2023 @ 11:05 AM

Molecular testing protocols for pathogen detection and diagnosing human diseases
require reliable and high-quality...

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Oligo synthesis and modifications Nucleic acid therapeutics General science


WHERE ARE ALL THE THERAPEUTIC APTAMERS?

Updated : Tue, August 9, 2022 @ 7:10 PM

New approaches that use aptamers as targeting agents may open the door to wider
clinical use in the future

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Molecular diagnostics Oligo synthesis and modifications qPCR General science


CHOOSING THE BEST QPCR PROBE CHEMISTRY FOR YOUR ASSAY


UPDATED : TUE, MAY 9, 2023 @ 10:40 AM


LET THE APPLICATION BE YOUR GUIDE WHEN DECIDING BETWEEN LNA, MGB AND BHQPLUS 

The many different chemistries available...

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Molecular diagnostics Disease detection


PIVOTING TO MONKEYPOX DIAGNOSTICS

UPDATED : WED, MARCH 22, 2023 @ 1:59 PM

Since 13 May 2022, reports of monkeypox cases began to appear globally in
regions not endemic to the monkeypox virus.1...

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SARS-CoV-2 Nucleic acid extraction Disease detection General science


MAKE YOUR DIAGNOSTIC WORKFLOWS MORE ADAPTABLE

UPDATED : FRI, DECEMBER 16, 2022 @ 3:39 PM

Since early 2020, diagnostic laboratories have had to manage patient sample
quantities being in a state of flux....

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SARS-CoV-2


PANDEMIC REFLECTIONS: ADAPTING TO TESTING PRIORITIES

UPDATED : TUE, MARCH 21, 2023 @ 3:23 PM


WHAT’S CHANGED FOR CLINICAL LABS AS WE ENTER THE THIRD YEAR OF COVID-19 TESTING?

COVID-19, the illness caused by...

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Molecular diagnostics qPCR General science


OPTIMISING AUTOMATED HIGH-THROUGHPUT PATHOGEN DETECTION WORKFLOWS

UPDATED : WED, MARCH 30, 2022 @ 4:00 PM

While both centralised and decentralised molecular diagnostics (MDx) testing
models play an important role in patient...

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Oligo synthesis and modifications Nucleic acid therapeutics


OVERCOMING MANUFACTURING CHALLENGES ASSOCIATED WITH NUCLEIC ACID THERAPEUTICS

Updated : Tue, March 21, 2023 @ 3:46 PM

This is the second blog in a two-part series exploring how oligonucleotide
modifications can support the advancement of...

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Molecular diagnostics qPCR General science


CONSIDERATIONS FOR RT-QPCR IN MOLECULAR POINT OF CARE TESTING DEVICES

UPDATED : FRI, APRIL 15, 2022 @ 8:58 PM

The COVID-19 pandemic has accelerated the uptake of point of care testing
(POCT), with simple, user-administered tests...

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Oligo synthesis and modifications Nucleic acid therapeutics


NUCLEIC ACID THERAPEUTICS FOR NEXT-GENERATION DISEASE MANAGEMENT

UPDATED : TUE, MARCH 21, 2023 @ 3:44 PM

This is the first blog post in a two-part series exploring how oligonucleotide
modifications can support the...

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qPCR SARS-CoV-2 General science


SOCIETY CAN’T HANDLE THE CAVEATS TO EACH TYPE OF COVID-19 TEST


UPDATED : FRI, FEBRUARY 11, 2022 @ 10:58 PM


BUT MEASUREMENT SCIENCE COULD HELP STEER US IN A BETTER, MORE INFORMED DIRECTION

COVID-19 tests can indicate the...

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SARS-CoV-2


PANDEMIC REFLECTIONS: IN THE FACE OF SARS-COV-2 VARIANTS, COVID-19 TESTING
REMAINS ESSENTIAL

UPDATED : TUE, JANUARY 11, 2022 @ 6:00 PM

What’s changed for clinical labs as we enter the third year of COVID-19 testing?

COVID-19, the illness caused by...

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SARS-CoV-2


PANDEMIC REFLECTIONS: UNPRECEDENTED DEMAND DRIVES COVID-19 TEST DEVELOPERS TO
GET CREATIVE

UPDATED : TUE, DECEMBER 28, 2021 @ 3:30 PM

What’s changed for clinical labs as we enter the third year of COVID-19 testing?

COVID-19, the illness caused by...

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Molecular diagnostics SARS-CoV-2


TECHNICAL BULLETIN: OMICRON IMPACT ON SARS-COV-2 MUTATION ANALYSIS AND
INVESTIGATION

Updated : Wed, March 22, 2023 @ 2:01 PM

The emergence of the Omicron lineage has quickly escalated to be a variant of
concern by the World Health Organization -

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SARS-CoV-2


PANDEMIC REFLECTIONS: THE WORLD IS SHORT STAFFED

UPDATED : THU, MARCH 9, 2023 @ 5:39 PM

What’s changed for clinical labs as we enter the third year of COVID-19 testing?

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Molecular diagnostics SARS-CoV-2


ENSURING OUR DIAGNOSTIC ASSAYS DETECT THE OMICRON VARIANT

UPDATED : FRI, DECEMBER 10, 2021 @ 2:34 AM

On 22 November 2021, The Network for Genomics Surveillance in South Africa
detected a new SARS-CoV-2 variant, named...

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Molecular diagnostics


EXTENSIONS TO THE IVDR - WHAT DIAGNOSTICS MANUFACTURERS AND SUPPLIERS NEED TO
KNOW

We're excited to announce that the proposal to extend certain key provisions of
the In Vitro Diagnostic Regulation (IVDR) (EU) 2017/746 has been adopted...

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Molecular diagnostics SARS-CoV-2 Disease detection


STREAMLINING DIAGNOSTIC WORKFLOWS FOR COMMON RESPIRATORY DISEASES, SUCH AS
SARS-COV-2, INFLUENZA AND RSV

UPDATED : TUE, NOVEMBER 30, 2021 @ 10:29 PM

A fourth wave of COVID-19 has already emerged in many countries and a newly
classified variant of concern, Omicron...

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Molecular diagnostics Oligo synthesis and modifications


INNOVATIVE APPLICATIONS FOR BLACK HOLE QUENCHER DYES

UPDATED : TUE, JANUARY 25, 2022 @ 10:23 PM

This is the first blog post in a two-part series highlighting how Black Hole
Quencher™ dyes can be incorporated into...

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Molecular diagnostics SARS-CoV-2


TECHNICAL BULLETIN: SARS-COV-2 MUTATION ANALYSIS AND INVESTIGATION

Updated : Thu, October 14, 2021 @ 10:01 PM

SARS-CoV-2 mutations and associated new variants are being reported regularly in
the media and scientific...

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Molecular diagnostics qPCR SARS-CoV-2 General science


CAN COVID-19 TESTING BE MADE MORE SUSTAINABLE DURING PROLONGED UNCERTAINTY?

UPDATED : THU, MARCH 31, 2022 @ 3:24 PM

In September 2021, Delta persists as the most prevalent variant worldwide1 due
to its high infectivity, causing surges...

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Molecular diagnostics


THE SURPRISING GLOBAL IMPACTS OF EUROPE'S IN VITRO DIAGNOSTIC REGULATION (IVDR)

UPDATED : WED, SEPTEMBER 15, 2021 @ 4:40 AM

A SHORTCUT TO UNDERSTANDING HOW TO PREPARE FOR IVDR

In today’s global environment, even small regulatory changes in...

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Molecular diagnostics SARS-CoV-2


TIPS FOR EARLY-STAGE MDX COMPANIES LAUNCHING NEW TESTS DURING COVID-19 TIMES

UPDATED : WED, NOVEMBER 9, 2022 @ 8:20 PM

The COVID-19 pandemic brought tremendous change to the molecular diagnostics
(MDx) industry, delivering opportunities...

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SARS-CoV-2


WASTEWATER SURVEILLANCE: A CRITICAL TOOL IN PANDEMIC MANAGEMENT

Updated : Thu, September 29, 2022 @ 7:57 PM

As SARS-CoV-2 variants continue to threaten public health, officials are looking
beyond clinical tests to track...

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SARS-CoV-2


TECHNICAL BULLETIN: EMERGING SARS-COV-2 MUTATIONS AND THEIR EFFECT ON THE IMMUNE
RESPONSE

UPDATED : THU, DECEMBER 16, 2021 @ 6:46 PM

Emerging SARS-CoV-2 variants of concern and variants of interest are defined by
agencies such as the World Health...

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Molecular diagnostics Genomics SARS-CoV-2 General science


GENOMIC SURVEILLANCE: 3 TECHNIQUES TO DETECT AND CHARACTERISE SARS-COV-2
VARIANTS

UPDATED : THU, MARCH 9, 2023 @ 5:37 PM

As the global population gains greater access to vaccines for COVID-19,
scientists and health officials continue to...

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Molecular diagnostics SARS-CoV-2


HOW DO SARS-COV-2 VARIANTS AFFECT PCR ASSAYS FOR COVID-19 TESTING?

UPDATED : THU, MARCH 9, 2023 @ 5:34 PM

Researchers have identified several variants of SARS-CoV-2 since they sequenced
the original viral strain responsible...

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Molecular diagnostics Genomics SARS-CoV-2 General science


BUILDING RESILIENCE INTO SARS-COV-2 TESTING WORKFLOWS: CONSIDERATIONS FOR
CHOOSING AN RNA ISOLATION METHOD

UPDATED : THU, FEBRUARY 3, 2022 @ 4:39 PM

Clinical and diagnostic labs worldwide are still experiencing supply chain
challenges with their SARS-CoV-2 testing...

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Molecular diagnostics Genomics SARS-CoV-2


PRESSING COVID-19 TESTING ISSUES OF TODAY AND THE NEAR FUTURE


UPDATED : TUE, OCTOBER 6, 2020 @ 6:45 PM


FOLLOWING UP WITH THE PANELISTS FROM OUR RECENT COVID-19 WEBINAR, PART 3 OF 3

In the previous two blog posts in this...

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Molecular diagnostics Genomics SARS-CoV-2


SENSITIVITY AND ACCURACY IN COVID-19 TESTING


UPDATED : TUE, OCTOBER 6, 2020 @ 6:42 PM


FOLLOWING UP WITH THE PANELISTS FROM OUR RECENT COVID-19 WEBINAR, PART 2 OF 3

In the face of a rapidly evolving...

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Molecular diagnostics Genomics SARS-CoV-2


SCALING UP COVID-19 VIRAL TESTING


UPDATED : TUE, OCTOBER 6, 2020 @ 6:45 PM


FOLLOWING UP WITH THE PANELISTS FROM OUR RECENT COVID-19 WEBINAR, PART 1 OF 3

The COVID-19 pandemic has presented...

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Molecular diagnostics Genomics qPCR SARS-CoV-2


ENABLING A RAPID RESPONSE TO COVID-19 BY HONEYWELL AND LGC, BIOSEARCH
TECHNOLOGIES

UPDATED : TUE, OCTOBER 6, 2020 @ 6:44 PM

As countries worldwide begin to ease lockdown restrictions during the pandemic
and prepare to return to “normal”...

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Molecular diagnostics Genomics qPCR SARS-CoV-2


ROBUST SUPPLY CHAINS AND OPEN TESTING SYSTEMS: HOW OUR AGBIO ROOTS MEET THE
FDA'S EUA PROCESS TO ENABLE SOLUTIONS TO THE COVID-19 PANDEMIC

Updated : Fri, December 18, 2020 @ 8:49 PM

It may seem strange that a company known for transforming the global seed
breeding industry is uniquely positioned...

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Molecular diagnostics Oligo synthesis and modifications Genomics SARS-CoV-2
General science


BEHIND THE SCENES: HOW OUR OLIGO SYNTHESIS TEAM CONTRIBUTES TO THE RELIABILITY
OF YOUR ASSAYS


UPDATED : WED, MARCH 22, 2023 @ 1:52 PM


WE’RE NOT REJECTING YOU, JUST YOUR OLIGO

PCR is arguably one of the most enabling technologies of modern molecular...

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Molecular diagnostics SARS-CoV-2


WHEN YOU DON’T NEED AN EUA FOR SARS-COV-2 TESTING

UPDATED : WED, NOVEMBER 25, 2020 @ 8:23 PM

On March 25, 2020, the US Food and Drug Administration (FDA) held the first of a
series of virtual town halls they...

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Molecular diagnostics Oligo synthesis and modifications Genomics SARS-CoV-2


ADDRESSING COVID-19 TOGETHER: LGC, BIOSEARCH TECHNOLOGIES AND SHANGHAI LIFERIVER
BIOTECHNOLOGY CO., LTD.

Updated : Tue, October 6, 2020 @ 6:44 PM

In the nearly three months since the first confirmed case of COVID-19, the
outbreak has become a global crisis, with...

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Molecular diagnostics Genomics SARS-CoV-2 General science


WHAT DIAGNOSTIC TEST MAKERS AND CLIA LABS IN THE US NEED TO KNOW ABOUT EMERGENCY
USE AUTHORIZATION (EUA)

Updated : Tue, March 21, 2023 @ 3:41 PM

*Since the original publication of this blog, LGC Biosearch Technologies is now
the only acceptable commercial supplier...

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Molecular diagnostics Genomics SARS-CoV-2


CORONAVIRUS OUTBREAK: COLLABORATION TO MEET THE CHALLENGE

{% video_player "embed_player" overrideable=False, type='scriptV4',
hide_playlist=True, viral_sharing=False, embed_button=False, autoplay=False,...
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Molecular diagnostics Next generation sequencing (NGS)


MOLECULAR DIAGNOSTICS: HOW CAN NGS LIVE UP TO ITS PROMISES?

UPDATED : TUE, OCTOBER 11, 2022 @ 8:43 PM

The development of new genomic sequencing techniques and bioinformatics analysis
in the last decade has led to...

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Genomics PCR-based genotyping Disease detection General science


HOW GENOTYPING IS AIDING IN THE FIGHT AGAINST MALARIA

Updated : Mon, September 19, 2022 @ 2:14 PM

3.2 billion people across 106 countries and territories, live in areas at risk
of malaria transmission. The serious...

Read more

RNA FISH Disease detection General science


SHINING A LIGHT ON HOW ZIKA VIRUS MAY SPREAD FROM MOTHERS TO HUMAN FETUSES

UPDATED : MON, MARCH 6, 2017 @ 4:37 PM

New research has, for the first time, found evidence suggesting the molecular
epidemiology of how the Zika virus spreads...

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Molecular diagnostics Oligo synthesis and modifications qPCR General science


PHOTOBLOG: BEHIND THE SCENES OF OLIGO SYNTHESIS

UPDATED : WED, DECEMBER 14, 2022 @ 5:04 PM

OLIGO SYNTHESIS PHOTO GLIMPSE

We’ve recently captured our talented manufacturing teams hard at work
building...

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Molecular diagnostics qPCR General science


RT-QPCR MOLECULAR DIAGNOSTICS ASSIST WORKERS AT THE FOREFRONT OF EBOLA OUTBREAK.

UPDATED : MON, SEPTEMBER 19, 2022 @ 2:13 PM

The largest recorded Ebola Virus Disease outbreak in history continues to
devastate the West African region. This...

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Molecular diagnostics qPCR General science


QPCR PROBES AT WORK: INNOVATIVE CLIA TEST FOR NSCLC STAGING

UPDATED : WED, OCTOBER 1, 2014 @ 4:51 PM

Non-squamous, Non-small cell lung cancer (NSCLC), the most common cause of death
in the US and globally, has recently...

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Molecular diagnostics


VISIT BIOSEARCH AT IVD TECHNOLOGY'S VIRTUAL CONFERENCE AND TRADESHOW

UPDATED : MON, SEPTEMBER 19, 2022 @ 2:07 PM

Biosearch Technologies is proud to sponsor the first IVD Technology Virtual
Conference and Tradeshow. This free...

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Molecular diagnostics


PILOTDX OLIGOS: EN ROUTE TO IVD

UPDATED : WED, OCTOBER 1, 2014 @ 4:42 PM

It can be difficult to transition a product from research to commercialization.
It’s simply not feasible to conduct...

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Agrigenomics NGS-based genotyping


INCREASING LIVESTOCK BREEDING PROFITABILITY WITH GENOMIC SELECTION

HOW DOES GENOMIC SELECTION INCREASE PROFITABILITY?

Livestock farmers’ and breeders’ profitability is directly related to the
quality of their stock. But this...
Read more

Agrigenomics NGS-based genotyping


US DEPT OF AGRICULTURE DIVES INTO BLUEBERRY AND CRANBERRY GENOTYPING

Every year over 1.5 million tonnes of blueberries and over half a million tonnes
of cranberries are produced. This is expected to rise significantly over the...

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Agrigenomics


WHY GENOME-EDITING CRISPR/CAS OFFERS HOPE FOR ACCELERATED SUSTAINABLE CROP
IMPROVEMENT IN OIL PALM

Updated : Thu, June 1, 2023 @ 4:09 PM

Oil palm, Elaeis guineensis Jacq., is the most productive oil crop in the world1
supplying around 40% of all globally...

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Agrigenomics PCR-based genotyping


ENHANCING STRAWBERRY BREEDING WITH PREDICTIVE MODELS, MARKER-ASSISTED SELECTION
AND GENOTYPING AUTOMATION

Updated : Tue, May 9, 2023 @ 10:48 AM

Around 159,200 tonnes of strawberries are produced annually in Japan across
5,020 ha in various regions around the...

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Agrigenomics PCR-based genotyping


HOW MGB PROBES COULD SOLVE YOUR COMPLEX PLANT GENOME GENOTYPING ISSUES

UPDATED : WED, MARCH 22, 2023 @ 1:48 PM

Genotyping plants can be a complex and frustrating process

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Agrigenomics PCR-based genotyping


EXPLORE THE VAST APPLICATIONS OF KASP GENOTYPING FOR PLANT BREEDING PROGRAMMES

UPDATED : WED, MARCH 22, 2023 @ 1:22 PM

Modern agriculture faces unprecedented challenges: increasing global
temperatures, water scarcity, less arable land to...

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Agrigenomics PCR-based genotyping NGS-based genotyping


GENETIC SOLUTIONS TO INFECTIOUS DISEASES IN AQUACULTURE

Updated : Mon, April 17, 2023 @ 8:33 AM

This is the second blog in a two-part series exploring solutions for infectious
diseases in aquaculture. In the first...

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Agrigenomics


INCREASING RESISTANCE TO AQUACULTURE DISEASE

Updated : Mon, April 17, 2023 @ 1:33 PM

This is the first blog in a two-part series exploring solutions for infectious
diseases in aquaculture. This blog post...

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Agrigenomics qPCR PCR-based genotyping General science


IMPROVING THE SUSTAINABILITY OF OIL PALM BREEDING PROGRAMMES USING
MARKER-ASSISTED SELECTION

UPDATED : WED, MARCH 9, 2022 @ 1:05 AM

African oil palm (Elaeis guineensis Jacq.) is a highly productive perennial crop
that is used widely in food, medicines,...

Read more

Agrigenomics qPCR PCR-based genotyping


INCREASING HYBRID RICE BREEDING EFFICIENCY WITH HIGH-THROUGHPUT GENOTYPING

Updated : Thu, January 12, 2023 @ 5:10 PM

Rice is the primary staple for more than half the world's population.1 With so
many people relying on the crop for...

Read more

Agrigenomics Next generation sequencing (NGS) NGS-based genotyping


A TARGETED GBS TECHNOLOGY FOR ALL BREEDING COMMUNITIES

UPDATED : TUE, DECEMBER 7, 2021 @ 10:11 PM

The decisions made by molecular breeding programmes have a substantial impact on
the world around us, from...

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Agrigenomics NGS-based genotyping


NGS SOLUTIONS FOR POLYPLOID PLANT BREEDING CHALLENGES

Updated : Fri, June 30, 2023 @ 2:19 PM

Many cultivated crops with agronomic significance, including wheat, peanut, oat,
banana, potato, coffee, blueberry and...

Read more

Agrigenomics PCR-based genotyping Nucleic acid extraction


4 STEPS TO OPTIMISE SAMPLE COLLECTION FOR AQUACULTURE GENOTYPING

Updated : Tue, September 7, 2021 @ 7:59 PM

Aquaculture breeding programmes adopt genomic technologies, including
genotyping, to increase genetic gain for...

Read more

Agrigenomics Next generation sequencing (NGS) Nucleic acid extraction


THE IMPORTANCE OF SAMPLE PROCESSING FOR SUCCESSFUL PLANT GENOTYPING BY NGS

UPDATED : THU, AUGUST 12, 2021 @ 11:51 PM

Informed plant breeding decisions help drive the field of agrigenomics towards
ever-increasing agricultural...

Read more

Agrigenomics Nucleic acid extraction


DON'T UNDERESTIMATE THE COMPLEXITY OF YOUR SAMPLE COMPOSITION

UPDATED : WED, AUGUST 4, 2021 @ 9:34 PM

A common mistake when initiating an agrigenomics project is failing to consider
specific sample composition before...

Read more

Agrigenomics Genomics General science


SELECTIVE BREEDING IN AQUACULTURE: ADVANCING BREEDING PROGRAMMES THROUGH
GENOMICS

Updated : Wed, December 14, 2022 @ 1:44 PM

The global demand for fish and fish products continues to increase as consumers
focus on health-conscious ways to...

Read more

Agrigenomics Genomics NGS-based genotyping


BEST PRACTICES FOR IMPLEMENTING TARGETED GENOTYPING BY SEQUENCING

UPDATED : FRI, NOVEMBER 20, 2020 @ 5:16 PM

In breeding programmes, selections based on a single or small number of markers
to target traits in marker assisted...

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Genomics PCR-based genotyping


HOW HIGH-THROUGHPUT GENOTYPING AUTOMATION AND KASP MARKER LIBRARIES CONNECT
RESEARCH LABS WITH COMMERCIAL BREEDERS TO ACCELERATE CROP IMPROVEMENT

UPDATED : WED, OCTOBER 7, 2020 @ 4:33 PM

“In July of 2015, I was a member of the radish genome project team. My task was
to examine genetic diversity of radish...

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Agrigenomics Genomics PCR-based genotyping


EMPLOYEE SPOTLIGHT: MEET DARSHNA "DUSTY" VYAS

UPDATED : FRI, SEPTEMBER 11, 2020 @ 9:52 PM

Darshna "Dusty" Vyas has been a Senior Scientist at LGC specialising in plant
genetics for the past 8 years Her...

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Agrigenomics Genomics PCR-based genotyping


ESTABLISHMENT OF KASP MARKER LIBRARY FOR GENETIC DIVERSITY ANALYSIS IN BRASSICA
RAPA  CROPS

Updated : Tue, July 14, 2020 @ 1:30 PM

Brassica  rapa crops are important sources of food, feed, and fuel in many parts
of the world and provide a unique...

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Genomics Next generation sequencing (NGS) NGS-based genotyping


NEW NGS SERVICE LAB NOW OPEN IN MIDDLETON, WI FOR EXPANDED GLOBAL SUPPORT

UPDATED : WED, APRIL 1, 2020 @ 8:12 PM

Back in September 2018, LGC acquired Lucigen Corporation. The ISO accredited
site is based in Middleton, Wisconsin and...

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Genomics PCR-based genotyping NGS-based genotyping


BACK TO BASICS - THE CRUCIAL STEP OF SAMPLE COLLECTION


UPDATED : MON, JANUARY 13, 2020 @ 5:08 PM


BEST PRACTICE IN SAMPLE COLLECTION FOR SEQSNP TARGETED GENOTYPING BY SEQUENCING
PROJECTS

When good goes in, great...

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Agrigenomics Genomics Next generation sequencing (NGS) NGS-based genotyping


GENOMIC SELECTION: CAN IT ACCELERATE LIVESTOCK BREEDING?

UPDATED : WED, MAY 1, 2019 @ 3:59 PM

Livestock supports the livelihoods and food security of almost 1.3 billion
people worldwide, contributing 40% of the...

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Agrigenomics PCR-based genotyping Next generation sequencing (NGS) NGS-based
genotyping


AGRIGENOMICS: HOW CAN NGS CONTRIBUTE TO GLOBAL FOOD SECURITY?

UPDATED : FRI, MAY 19, 2023 @ 8:53 AM

“Experience of artificial fertilisation, such as is effected with ornamental
plants in order to obtain new variations in...

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Agrigenomics Next generation sequencing (NGS) NGS-based genotyping


HOW TARGETED GBS-DRIVEN GENOMIC SELECTION CAN HELP YOU GET TO MARKET FASTER

UPDATED : THU, MAY 25, 2023 @ 11:32 AM

Plant and animal breeding programmes often take generations to improve quality
and yield but using a genotyping protocol...

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Genomics NGS-based genotyping


GENOMIC SELECTION: METHODS IN CROP AND ANIMAL BREEDING

UPDATED : WED, JANUARY 9, 2019 @ 5:03 PM

Genomic selection: 6 factors to consider when choosing between targeted GBS and
microarrays

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Agrigenomics Next generation sequencing (NGS) NGS-based genotyping


OUR HUNGRY PLANET: NEW TOOLS IN AGRIGENOMICS ARE KEY TO FOOD SECURITY

UPDATED : TUE, DECEMBER 11, 2018 @ 4:32 PM

Food security is a major global threat and traditional methods of plant and
animal breeding will not be sufficient...

Read more

PCR-based genotyping


ACCELERATING RICE IMPROVEMENT IN SOUTH ASIA

Updated : Thu, July 26, 2018 @ 4:41 PM

Diversity is the spice of life and is also key to breeding rice that delivers
increased yields. Rice is a crucial staple...

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Agrigenomics Genomics NGS-based genotyping General science


TACKLING FOOD CRISIS THROUGH COST EFFECTIVE, TARGET ENRICHED SEQUENCING

UPDATED : MON, SEPTEMBER 19, 2022 @ 2:16 PM

With the global population predicted to reach 9 billion people within the next
35 years, we will need to double the...

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Agrigenomics Genomics PCR-based genotyping


NEW SNPS IDENTIFIED IN THE HUNT FOR NEW GENETIC WEAPONS TARGETING LEAF RUST IN
WHEAT

UPDATED : WED, NOVEMBER 22, 2017 @ 1:44 PM

Wheat is one of the three most important crops for human and livestock feed.
With an ever-increasing global...

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Agrigenomics Genomics PCR-based genotyping


SUPER-CROPS HELPING TO FEED AFRICA

UPDATED : TUE, JULY 10, 2018 @ 9:08 PM

Our world population is growing at a tremendous rate and by 2050, Africa’s
population alone is set to hit over 2.5...

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Genomics PCR-based genotyping Disease detection General science


HOW GENOTYPING IS AIDING IN THE FIGHT AGAINST MALARIA

Updated : Mon, September 19, 2022 @ 2:14 PM

3.2 billion people across 106 countries and territories, live in areas at risk
of malaria transmission. The serious...

Read more

Genomics PCR-based genotyping General science


OVERCOMING DROUGHT-INTOLERANCE IN MAIZE TO FEED THE GROWING ASIAN POPULATION

UPDATED : WED, FEBRUARY 15, 2017 @ 4:23 PM

Demand for maize is increasing due to an increased number of people
transitioning to meat-based diets driving demand...

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Agrigenomics Genomics PCR-based genotyping NGS-based genotyping General science


HELPING TO FEED THE WORLD WITH GENOTYPING BY SEQUENCING

UPDATED : WED, JANUARY 18, 2017 @ 2:13 PM

Many areas critical to improved agricultural production require robust and
scalable genotyping platforms to enable...

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PCR-based genotyping


FASTER, STRONGER, QUICKER: SSR TO KASP WILL GET YOU THERE

UPDATED : MON, JANUARY 9, 2017 @ 3:20 PM

Screen more markers faster and bring crops with superior traits to the market
quicker.

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Agrigenomics


A COMPLETE ECOSYSTEM TO ACCELERATE BREEDING PROGRAMS [INFOGRAPHIC]

UPDATED : TUE, JUNE 28, 2016 @ 9:00 PM

Modern breeding methods rely on the identification and utilization of molecular
markers associated with traits...

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qPCR PCR-based genotyping General science


A SUCCESSFUL DUO FOR ACCURATE, SPEEDY, AND ECONOMICAL SNP GENOTYPING

UPDATED : MON, SEPTEMBER 19, 2022 @ 2:12 PM

Single Nucleotide Polymorphisms (SNPs) have been widely studied for over 15
years, and have applications in...

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Oligo synthesis and modifications Nucleic acid therapeutics


SYNTHESIZING YOUR OWN OLIGONUCLEOTIDES: FAQS

Considering bringing oligo synthesis in-house? Here are some commonly asked
questions that we receive, grouped into four sections. You can jump to a
section...
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Oligo synthesis and modifications General science


“CLICK” YOUR WAY TOWARDS DISCOVERY AND INNOVATION

Labelling, linking or modifying biomolecules used to be a laborious process,
requiring customised complex synthetic pathways that yield little product....

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Molecular diagnostics qPCR


MINIMISING ANTIBIOTIC DEPENDENCY FOR TREATING UTIS AND STIS

Antimicrobial resistance (AMR) across bacterial species is developing rapidly,
compounded by the improper use of antimicrobial agents that accelerates the...
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Oligo synthesis and modifications Nucleic acid therapeutics


WHAT’S THE LATEST IN ASO AND SIRNA TECHNOLOGIES?

Over the last few decades, researchers have made impressive strides in
developing methods to overcome the delivery, stability, and specificity
challenges of...

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Molecular diagnostics Nucleic acid extraction


DITCH THE SPIN COLUMNS WITHOUT COMPROMISING ON NUCLEIC ACID QUALITY

Whether you’re working with samples for PCR or sequencing, it's worth
questioning what type of extraction or purification method would work well with
your...
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Molecular diagnostics Oligo synthesis and modifications qPCR General science


A WAY TO SIMPLIFY DESIGN AND INTERPRETATION OF YOUR QPCR ASSAYS


UPDATED : FRI, MAY 5, 2023 @ 2:34 PM


HOW DOES A BHQ DYE CONTRIBUTE TO PRODUCING SUPERIOR DATA FROM YOUR ASSAYS?

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Oligo synthesis and modifications Nucleic acid therapeutics


WHICH CONTROLLED PORE GLASS IS RIGHT FOR YOUR THERAPEUTIC APPLICATION?

UPDATED : MON, JUNE 26, 2023 @ 10:24 AM

Oligonucleotide therapeutics have unlocked new treatment possibilities for rare
and fatal diseases often associated...

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Oligo synthesis and modifications General science


5-NITROINDOLE – A UNIVERSAL BASE OLIGO MODIFICATION

Updated : Tue, May 9, 2023 @ 10:51 AM

In the next edition of the “Know your oligo mod” series, we look at a universal
base analogue for oligonucleotide...

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Molecular diagnostics Oligo synthesis and modifications


WHAT’S NEXT FOR APTAMERS IN DIAGNOSTICS?

UPDATED : TUE, MAY 9, 2023 @ 11:01 AM

Originally developed in the early 1990s, aptamers have long been heralded as an
antibody alternative for detection...

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Molecular diagnostics Nucleic acid extraction General science


HOW TO SELECT AN EFFECTIVE NUCLEIC ACID ISOLATION METHOD FOR HUMAN DIAGNOSTICS?

Updated : Tue, May 9, 2023 @ 11:05 AM

Molecular testing protocols for pathogen detection and diagnosing human diseases
require reliable and high-quality...

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qPCR General science


TAQ POLYMERASE: WHAT IS IT AND ITS APPLICATIONS

UPDATED : WED, DECEMBER 14, 2022 @ 1:54 PM

When the polymerase chain reaction (PCR) was first described, the Klenow
fragment of Escherichia coli DNA...

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Oligo synthesis and modifications Nucleic acid therapeutics General science


WHERE ARE ALL THE THERAPEUTIC APTAMERS?

Updated : Tue, August 9, 2022 @ 7:10 PM

New approaches that use aptamers as targeting agents may open the door to wider
clinical use in the future

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Molecular diagnostics Oligo synthesis and modifications qPCR General science


CHOOSING THE BEST QPCR PROBE CHEMISTRY FOR YOUR ASSAY


UPDATED : TUE, MAY 9, 2023 @ 10:40 AM


LET THE APPLICATION BE YOUR GUIDE WHEN DECIDING BETWEEN LNA, MGB AND BHQPLUS 

The many different chemistries available...

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SARS-CoV-2 Nucleic acid extraction Disease detection General science


MAKE YOUR DIAGNOSTIC WORKFLOWS MORE ADAPTABLE

UPDATED : FRI, DECEMBER 16, 2022 @ 3:39 PM

Since early 2020, diagnostic laboratories have had to manage patient sample
quantities being in a state of flux....

Read more

Molecular diagnostics qPCR General science


OPTIMISING AUTOMATED HIGH-THROUGHPUT PATHOGEN DETECTION WORKFLOWS

UPDATED : WED, MARCH 30, 2022 @ 4:00 PM

While both centralised and decentralised molecular diagnostics (MDx) testing
models play an important role in patient...

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Oligo synthesis and modifications Nucleic acid therapeutics


OVERCOMING MANUFACTURING CHALLENGES ASSOCIATED WITH NUCLEIC ACID THERAPEUTICS

Updated : Tue, March 21, 2023 @ 3:46 PM

This is the second blog in a two-part series exploring how oligonucleotide
modifications can support the advancement of...

Read more

Agrigenomics qPCR PCR-based genotyping General science


IMPROVING THE SUSTAINABILITY OF OIL PALM BREEDING PROGRAMMES USING
MARKER-ASSISTED SELECTION

UPDATED : WED, MARCH 9, 2022 @ 1:05 AM

African oil palm (Elaeis guineensis Jacq.) is a highly productive perennial crop
that is used widely in food, medicines,...

Read more

Molecular diagnostics qPCR General science


CONSIDERATIONS FOR RT-QPCR IN MOLECULAR POINT OF CARE TESTING DEVICES

UPDATED : FRI, APRIL 15, 2022 @ 8:58 PM

The COVID-19 pandemic has accelerated the uptake of point of care testing
(POCT), with simple, user-administered tests...

Read more

Oligo synthesis and modifications Nucleic acid therapeutics


NUCLEIC ACID THERAPEUTICS FOR NEXT-GENERATION DISEASE MANAGEMENT

UPDATED : TUE, MARCH 21, 2023 @ 3:44 PM

This is the first blog post in a two-part series exploring how oligonucleotide
modifications can support the...

Read more

qPCR SARS-CoV-2 General science


SOCIETY CAN’T HANDLE THE CAVEATS TO EACH TYPE OF COVID-19 TEST


UPDATED : FRI, FEBRUARY 11, 2022 @ 10:58 PM


BUT MEASUREMENT SCIENCE COULD HELP STEER US IN A BETTER, MORE INFORMED DIRECTION

COVID-19 tests can indicate the...

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Oligo synthesis and modifications


LEVERAGING QUENCHING EFFICIENCY OF BLACK HOLE QUENCHER DYES FOR PCR AND BEYOND


UPDATED : TUE, JANUARY 25, 2022 @ 8:30 PM


MORE INNOVATIVE APPLICATIONS FOR BLACK HOLE QUENCHER (BHQ) DYES


IN IMAGING AND DETECTION ASSAY DEVELOPMENT,...

Read more

RNA FISH General science


FIVE WAYS CONTROLS CAN DEMYSTIFY YOUR STELLARIS™ RNA FISH EXPERIMENT

UPDATED : WED, MARCH 22, 2023 @ 1:23 PM

Stellaris controls, who needs ‘em? We all do. Especially if it’s your first time
interrogating a sample with a new...

Read more

Agrigenomics qPCR PCR-based genotyping


INCREASING HYBRID RICE BREEDING EFFICIENCY WITH HIGH-THROUGHPUT GENOTYPING

Updated : Thu, January 12, 2023 @ 5:10 PM

Rice is the primary staple for more than half the world's population.1 With so
many people relying on the crop for...

Read more

Oligo synthesis and modifications General science


OLIGONUCLEOTIDE SYNTHESIS BASICS: KEY TAKEAWAYS FOR POST-SYNTHESIS PROCESSING

Updated : Wed, December 14, 2022 @ 4:45 PM

This is the final blog post in a three-part educational series about best
practices for in-house oligonucleotide...

Read more

Molecular diagnostics Oligo synthesis and modifications


INNOVATIVE APPLICATIONS FOR BLACK HOLE QUENCHER DYES

UPDATED : TUE, JANUARY 25, 2022 @ 10:23 PM

This is the first blog post in a two-part series highlighting how Black Hole
Quencher™ dyes can be incorporated into...

Read more

Oligo synthesis and modifications General science


OLIGONUCLEOTIDE SYNTHESIS BASICS: 4 KEY TAKEAWAYS FOR IN-HOUSE OLIGO PRODUCTION

Updated : Wed, December 14, 2022 @ 4:43 PM

This is the second blog post in a three-part educational series about best
practices for in-house oligonucleotide...

Read more

qPCR General science


8 QPCR AMPLIFICATION PLOT QUESTIONS ANSWERED

Updated : Thu, February 3, 2022 @ 6:10 PM

When results from your qPCR assays aren’t quite what you expected, it can be
challenging to understand what went...

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Molecular diagnostics qPCR SARS-CoV-2 General science


CAN COVID-19 TESTING BE MADE MORE SUSTAINABLE DURING PROLONGED UNCERTAINTY?

UPDATED : THU, MARCH 31, 2022 @ 3:24 PM

In September 2021, Delta persists as the most prevalent variant worldwide1 due
to its high infectivity, causing surges...

Read more

Oligo synthesis and modifications General science


OLIGONUCLEOTIDE SYNTHESIS BASICS: INTRODUCTION TO PHOSPHORAMIDITE CHEMISTRY

UPDATED : WED, DECEMBER 14, 2022 @ 4:43 PM

This is the first blog post in a three-part educational series about best
practices for in-house oligonucleotide...

Read more

Agrigenomics PCR-based genotyping Nucleic acid extraction


4 STEPS TO OPTIMISE SAMPLE COLLECTION FOR AQUACULTURE GENOTYPING

Updated : Tue, September 7, 2021 @ 7:59 PM

Aquaculture breeding programmes adopt genomic technologies, including
genotyping, to increase genetic gain for...

Read more

Agrigenomics Next generation sequencing (NGS) Nucleic acid extraction


THE IMPORTANCE OF SAMPLE PROCESSING FOR SUCCESSFUL PLANT GENOTYPING BY NGS

UPDATED : THU, AUGUST 12, 2021 @ 11:51 PM

Informed plant breeding decisions help drive the field of agrigenomics towards
ever-increasing agricultural...

Read more

Agrigenomics Nucleic acid extraction


DON'T UNDERESTIMATE THE COMPLEXITY OF YOUR SAMPLE COMPOSITION

UPDATED : WED, AUGUST 4, 2021 @ 9:34 PM

A common mistake when initiating an agrigenomics project is failing to consider
specific sample composition before...

Read more

Agrigenomics Genomics General science


SELECTIVE BREEDING IN AQUACULTURE: ADVANCING BREEDING PROGRAMMES THROUGH
GENOMICS

Updated : Wed, December 14, 2022 @ 1:44 PM

The global demand for fish and fish products continues to increase as consumers
focus on health-conscious ways to...

Read more

Molecular diagnostics Genomics SARS-CoV-2 General science


GENOMIC SURVEILLANCE: 3 TECHNIQUES TO DETECT AND CHARACTERISE SARS-COV-2
VARIANTS

UPDATED : THU, MARCH 9, 2023 @ 5:37 PM

As the global population gains greater access to vaccines for COVID-19,
scientists and health officials continue to...

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Agrigenomics Genomics NGS-based genotyping


BEST PRACTICES FOR IMPLEMENTING TARGETED GENOTYPING BY SEQUENCING

UPDATED : FRI, NOVEMBER 20, 2020 @ 5:16 PM

In breeding programmes, selections based on a single or small number of markers
to target traits in marker assisted...

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Molecular diagnostics Genomics SARS-CoV-2 General science


BUILDING RESILIENCE INTO SARS-COV-2 TESTING WORKFLOWS: CONSIDERATIONS FOR
CHOOSING AN RNA ISOLATION METHOD

UPDATED : THU, FEBRUARY 3, 2022 @ 4:39 PM

Clinical and diagnostic labs worldwide are still experiencing supply chain
challenges with their SARS-CoV-2 testing...

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Genomics PCR-based genotyping


HOW HIGH-THROUGHPUT GENOTYPING AUTOMATION AND KASP MARKER LIBRARIES CONNECT
RESEARCH LABS WITH COMMERCIAL BREEDERS TO ACCELERATE CROP IMPROVEMENT

UPDATED : WED, OCTOBER 7, 2020 @ 4:33 PM

“In July of 2015, I was a member of the radish genome project team. My task was
to examine genetic diversity of radish...

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Agrigenomics Genomics PCR-based genotyping


EMPLOYEE SPOTLIGHT: MEET DARSHNA "DUSTY" VYAS

UPDATED : FRI, SEPTEMBER 11, 2020 @ 9:52 PM

Darshna "Dusty" Vyas has been a Senior Scientist at LGC specialising in plant
genetics for the past 8 years Her...

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Molecular diagnostics Genomics SARS-CoV-2


PRESSING COVID-19 TESTING ISSUES OF TODAY AND THE NEAR FUTURE


UPDATED : TUE, OCTOBER 6, 2020 @ 6:45 PM


FOLLOWING UP WITH THE PANELISTS FROM OUR RECENT COVID-19 WEBINAR, PART 3 OF 3

In the previous two blog posts in this...

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Molecular diagnostics Genomics SARS-CoV-2


SENSITIVITY AND ACCURACY IN COVID-19 TESTING


UPDATED : TUE, OCTOBER 6, 2020 @ 6:42 PM


FOLLOWING UP WITH THE PANELISTS FROM OUR RECENT COVID-19 WEBINAR, PART 2 OF 3

In the face of a rapidly evolving...

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Molecular diagnostics Genomics SARS-CoV-2


SCALING UP COVID-19 VIRAL TESTING


UPDATED : TUE, OCTOBER 6, 2020 @ 6:45 PM


FOLLOWING UP WITH THE PANELISTS FROM OUR RECENT COVID-19 WEBINAR, PART 1 OF 3

The COVID-19 pandemic has presented...

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Molecular diagnostics Genomics qPCR SARS-CoV-2


ENABLING A RAPID RESPONSE TO COVID-19 BY HONEYWELL AND LGC, BIOSEARCH
TECHNOLOGIES

UPDATED : TUE, OCTOBER 6, 2020 @ 6:44 PM

As countries worldwide begin to ease lockdown restrictions during the pandemic
and prepare to return to “normal”...

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Agrigenomics Genomics PCR-based genotyping


ESTABLISHMENT OF KASP MARKER LIBRARY FOR GENETIC DIVERSITY ANALYSIS IN BRASSICA
RAPA  CROPS

Updated : Tue, July 14, 2020 @ 1:30 PM

Brassica  rapa crops are important sources of food, feed, and fuel in many parts
of the world and provide a unique...

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Molecular diagnostics Genomics qPCR SARS-CoV-2


ROBUST SUPPLY CHAINS AND OPEN TESTING SYSTEMS: HOW OUR AGBIO ROOTS MEET THE
FDA'S EUA PROCESS TO ENABLE SOLUTIONS TO THE COVID-19 PANDEMIC

Updated : Fri, December 18, 2020 @ 8:49 PM

It may seem strange that a company known for transforming the global seed
breeding industry is uniquely positioned...

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Molecular diagnostics Oligo synthesis and modifications Genomics SARS-CoV-2
General science


BEHIND THE SCENES: HOW OUR OLIGO SYNTHESIS TEAM CONTRIBUTES TO THE RELIABILITY
OF YOUR ASSAYS


UPDATED : WED, MARCH 22, 2023 @ 1:52 PM


WE’RE NOT REJECTING YOU, JUST YOUR OLIGO

PCR is arguably one of the most enabling technologies of modern molecular...

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Genomics Next generation sequencing (NGS) NGS-based genotyping


NEW NGS SERVICE LAB NOW OPEN IN MIDDLETON, WI FOR EXPANDED GLOBAL SUPPORT

UPDATED : WED, APRIL 1, 2020 @ 8:12 PM

Back in September 2018, LGC acquired Lucigen Corporation. The ISO accredited
site is based in Middleton, Wisconsin and...

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Molecular diagnostics Oligo synthesis and modifications Genomics SARS-CoV-2


ADDRESSING COVID-19 TOGETHER: LGC, BIOSEARCH TECHNOLOGIES AND SHANGHAI LIFERIVER
BIOTECHNOLOGY CO., LTD.

Updated : Tue, October 6, 2020 @ 6:44 PM

In the nearly three months since the first confirmed case of COVID-19, the
outbreak has become a global crisis, with...

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Molecular diagnostics Genomics SARS-CoV-2 General science


WHAT DIAGNOSTIC TEST MAKERS AND CLIA LABS IN THE US NEED TO KNOW ABOUT EMERGENCY
USE AUTHORIZATION (EUA)

Updated : Tue, March 21, 2023 @ 3:41 PM

*Since the original publication of this blog, LGC Biosearch Technologies is now
the only acceptable commercial supplier...

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Molecular diagnostics Genomics SARS-CoV-2


CORONAVIRUS OUTBREAK: COLLABORATION TO MEET THE CHALLENGE

{% video_player "embed_player" overrideable=False, type='scriptV4',
hide_playlist=True, viral_sharing=False, embed_button=False, autoplay=False,...
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Genomics PCR-based genotyping NGS-based genotyping


BACK TO BASICS - THE CRUCIAL STEP OF SAMPLE COLLECTION


UPDATED : MON, JANUARY 13, 2020 @ 5:08 PM


BEST PRACTICE IN SAMPLE COLLECTION FOR SEQSNP TARGETED GENOTYPING BY SEQUENCING
PROJECTS

When good goes in, great...

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Agrigenomics Genomics Next generation sequencing (NGS) NGS-based genotyping


GENOMIC SELECTION: CAN IT ACCELERATE LIVESTOCK BREEDING?

UPDATED : WED, MAY 1, 2019 @ 3:59 PM

Livestock supports the livelihoods and food security of almost 1.3 billion
people worldwide, contributing 40% of the...

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Genomics


THE WOMEN OF LGC, BIOSEARCH TECHNOLOGIES

UPDATED : FRI, MARCH 29, 2019 @ 4:39 PM

We've heard it said for years, "TV will rot your brain". But in the case of our
three colleagues below, that definitely...

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Genomics NGS-based genotyping


GENOMIC SELECTION: METHODS IN CROP AND ANIMAL BREEDING

UPDATED : WED, JANUARY 9, 2019 @ 5:03 PM

Genomic selection: 6 factors to consider when choosing between targeted GBS and
microarrays

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Genomics General science


REVOLUTIONISING CANCER TREATMENT ONE ARRAY AT A TIME

UPDATED : MON, SEPTEMBER 19, 2022 @ 2:14 PM

While the science of pharmacogenomics has been around for years, its popularity
is starting to pick up steam as...

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Genomics Nucleic acid extraction


PACK IT UP, PACK IT IN, LET ME BEGIN: A LOOK AT THE FUTURE OF DNA DATA STORAGE

UPDATED : THU, JUNE 28, 2018 @ 4:28 PM

Imagine a time capsule the size of a shoebox that holds all the information
currently on the internet that can be stored...

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RNA FISH Genomics


WARNING! PITFALLS AHEAD: HOW TO AVOID THE MOST COMMON STELLARIS RNA FISH
MISTAKES

UPDATED : TUE, MAY 29, 2018 @ 3:47 PM

Ever wake up in the morning just feeling like a rock star, or maybe like Francis
Crick, Rosalind Franklin or Maurice...

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RNA FISH Genomics


SHINING A LIGHT ON GENE EXPRESSION AND REGULATION ONE CELL AT A TIME

UPDATED : MON, APRIL 30, 2018 @ 1:53 PM

To truly understand complex diseases such as cancer, scientists need access to
tools that don’t just average data...

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Genomics


THE WOMEN OF LGC

UPDATED : THU, MARCH 29, 2018 @ 4:00 PM

Ask any little girl what they want to be when they grow up and you may hear
things like, princess, ballerina, pop star,...

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RNA FISH Genomics


IN CASE YOU MISSED IT: STELLARIS RNA FISH LUNCH-AND-LEARN

UPDATED : TUE, JANUARY 16, 2018 @ 4:50 PM

Stellaris® RNA FISH (fluorescence in situ hybridization) is an RNA visualization
method that allows simultaneous...

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Agrigenomics Genomics NGS-based genotyping General science


TACKLING FOOD CRISIS THROUGH COST EFFECTIVE, TARGET ENRICHED SEQUENCING

UPDATED : MON, SEPTEMBER 19, 2022 @ 2:16 PM

With the global population predicted to reach 9 billion people within the next
35 years, we will need to double the...

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Agrigenomics Genomics PCR-based genotyping


NEW SNPS IDENTIFIED IN THE HUNT FOR NEW GENETIC WEAPONS TARGETING LEAF RUST IN
WHEAT

UPDATED : WED, NOVEMBER 22, 2017 @ 1:44 PM

Wheat is one of the three most important crops for human and livestock feed.
With an ever-increasing global...

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Agrigenomics Genomics PCR-based genotyping


SUPER-CROPS HELPING TO FEED AFRICA

UPDATED : TUE, JULY 10, 2018 @ 9:08 PM

Our world population is growing at a tremendous rate and by 2050, Africa’s
population alone is set to hit over 2.5...

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Genomics PCR-based genotyping Disease detection General science


HOW GENOTYPING IS AIDING IN THE FIGHT AGAINST MALARIA

Updated : Mon, September 19, 2022 @ 2:14 PM

3.2 billion people across 106 countries and territories, live in areas at risk
of malaria transmission. The serious...

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RNA FISH Genomics General science


LUNCH & LEARN: STELLARIS RNA FISH

UPDATED : THU, JULY 6, 2017 @ 3:22 PM

Recently LGC Genomics hosted a lunch and learn Stellaris® seminar at the Helen
Diller Cancer Institute at UCSF with our...

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Genomics qPCR General science


IT’S OFFICIAL! PERSONAL HEALTH BECOMES FIRST CHINA DEMONSTRATION LABORATORY SITE
FOR LGC’S NEXAR SYSTEM

Updated : Mon, September 19, 2022 @ 2:07 PM

LGC's Genomics Division has signed a memorandum of understanding (MOU) with
Chinese health management expert...

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qPCR General science


DIGITAL PCR – IMPROVING REPRODUCIBLE MOLECULAR METHODS IN THE CLINIC

UPDATED : THU, APRIL 6, 2017 @ 3:40 PM

A recent study coordinated by LGC and published in the journal Analytical
Chemistry, has demonstrated the potential of...

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RNA FISH Disease detection General science


SHINING A LIGHT ON HOW ZIKA VIRUS MAY SPREAD FROM MOTHERS TO HUMAN FETUSES

UPDATED : MON, MARCH 6, 2017 @ 4:37 PM

New research has, for the first time, found evidence suggesting the molecular
epidemiology of how the Zika virus spreads...

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Genomics PCR-based genotyping General science


OVERCOMING DROUGHT-INTOLERANCE IN MAIZE TO FEED THE GROWING ASIAN POPULATION

UPDATED : WED, FEBRUARY 15, 2017 @ 4:23 PM

Demand for maize is increasing due to an increased number of people
transitioning to meat-based diets driving demand...

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Genomics General science


AUTOMATE TO ACCELERATE AND SCALE-UP SNP-BASED GENOTYPING WORKFLOWS!

UPDATED : MON, SEPTEMBER 19, 2022 @ 2:05 PM

The advent of and ongoing improvements to next-generation sequencing
technologies is driving the continuing and...

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Genomics General science


MULTIPLE MISUNDERSTANDINGS: LEARNING FROM GENETIC DETERMINISM

UPDATED : MON, JANUARY 23, 2017 @ 4:27 PM

Nature versus nurture. It’s a tale as old as time.

When Craig Venter made the comment after the human genome sequence...

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Agrigenomics Genomics PCR-based genotyping NGS-based genotyping General science


HELPING TO FEED THE WORLD WITH GENOTYPING BY SEQUENCING

UPDATED : WED, JANUARY 18, 2017 @ 2:13 PM

Many areas critical to improved agricultural production require robust and
scalable genotyping platforms to enable...

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Genomics qPCR General science


MULTIPLEX YOUR QPCR AND WALK-AWAY

UPDATED : MON, SEPTEMBER 19, 2022 @ 2:15 PM

It seems everyone wants to do more with less, and automate the process as well.
But this can cause a number of...

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RNA FISH Genomics General science


A STELLAR-IS YEAR IN THE MAKING

UPDATED : MON, SEPTEMBER 19, 2022 @ 2:12 PM 

It wouldn't be fair to close out 2016 without showcasing the stellar year that
Stellaris® RNA FISH has had. Take a...

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Genomics General science


BUDDY UP: THE DOUBLE HELIX

UPDATED : MON, NOVEMBER 28, 2016 @ 11:31 PM

The secret of life. That’s what Francis Crick and James Watson claimed they had
discovered back in Cambridge,...

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Genomics General science


GENES, PROTEINS & DNA: OUR HEREDITARY SOFTWARE

UPDATED : MON, NOVEMBER 21, 2016 @ 3:32 PM

In the early 1900s, scientists found that the function of genes was to make
proteins, disproving the earlier idea...

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Genomics General science


"X" MARKS THE SPOT: A CLOSER LOOK AT CHROMOSOMES

UPDATED : WED, MARCH 29, 2023 @ 10:51 AM

The strands of DNA in your cells are organized into pieces called chromosomes.
Chromosomes are further organized into...

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Genomics General science


EXCEL AUTOCORRECT FAILS THE GENOMICS COMMUNITY - ARE YOUR RESULTS EXCELLENT OR
EXCEL-NOT?

UPDATED : MON, SEPTEMBER 19, 2022 @ 2:13 PM

Researchers from the Baker IDI Heart and Diabetes Institute in Melbourne,
Australia have blamed a default...

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qPCR General science


QPCR-BASED MOLECULAR DIAGNOSTICS AT THE FOREFRONT OF ZIKA SURVEILLANCE

UPDATED : WED, MARCH 29, 2023 @ 11:04 AM

As the Zika virus outbreak spreads, a wave of international concern has grown,
and scientists have scrambled to...

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Oligo synthesis and modifications General science


KNOW YOUR OLIGO MOD: THIO C6 LINKER

UPDATED : WED, MARCH 29, 2023 @ 10:55 AM


THIO C6 LINKER (THIOHEXYL) 

We continue our “Know Your Oligo Mod” series with another versatile custom
oligonucleotide...

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Molecular diagnostics Oligo synthesis and modifications qPCR General science


PHOTOBLOG: BEHIND THE SCENES OF OLIGO SYNTHESIS

UPDATED : WED, DECEMBER 14, 2022 @ 5:04 PM

OLIGO SYNTHESIS PHOTO GLIMPSE

We’ve recently captured our talented manufacturing teams hard at work
building...

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qPCR General science


NOVA IS THE NEW BLACK

Updated : Mon, April 24, 2023 @ 8:54 AM

LGC Biosearch Technologies has developed a new qPCR probe format powered by
Black Hole Quencher™ technology known as ...

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RNA FISH General science


IMAGING STELLARIS ASSAYS PART III: CREATING PROFESSIONAL, PUBLICATION-READY
IMAGES

Updated : Wed, August 16, 2017 @ 9:15 AM

Here is the final installment of our “Imaging Stellaris Assays” blog series. In
our two previous posts, we’ve gone...

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RNA FISH General science


DESIGNING STELLARIS RNA FISH PROBES PART I: INCREASING PROBE COUNT

Updated : Tue, September 27, 2022 @ 2:32 PM

Stellaris® RNA FISH is a novel technology that allows for the detection of
single or clustered RNAs in fixed cells...

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Oligo synthesis and modifications qPCR General science


KNOW YOUR OLIGO MOD: 3' SPACER C3

UPDATED : WED, MARCH 29, 2023 @ 10:54 AM

This week, we continue our Know your oligo mod blog series and we will focus on
a very basic, yet extremely versatile...

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RNA FISH General science


IMAGING STELLARIS ASSAYS PART II: HOW TO ACQUIRE STUNNING IMAGES

UPDATED : WED, AUGUST 16, 2017 @ 9:13 AM

Here we continue our “Imaging Stellaris Assays” blog series. We last left off
talking about the most important...

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RNA FISH General science


RUNAWAY RNA STAYS PUT

UPDATED : TUE, MARCH 21, 2023 @ 3:53 PM

The cleavage and polyadenylation event, the final trimming in the molecular mRNA
barbershop, normally releases both the...

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RNA FISH General science


IMAGING STELLARIS ASSAYS PART I: GET TO KNOW YOUR MICROSCOPE

UPDATED : WED, AUGUST 16, 2017 @ 9:42 PM

Stellaris® FISH is an RNA detection technology performed by means of in situ
hybridization. This technology and all of...

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Oligo synthesis and modifications General science


THE AGCT’S OF DNA SYNTHESIS

UPDATED : WED, MARCH 29, 2023 @ 10:38 AM

Chemically synthesized DNA has become an indispensable tool for molecular
biologists in the fields of medicine,...

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Oligo synthesis and modifications General science


KNOW YOUR OLIGO MOD: BHQ® (BLACK HOLE QUENCHER®) NON-FLUORESCENT QUENCHERS

UPDATED : FRI, JANUARY 13, 2023 @ 11:35 AM

In this instalment, we will cover the basics of LGC Biosearch Technologies’ line
of proprietary non-fluorescent...

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RNA FISH qPCR General science


AND THE CONSENSUS (SEQUENCE) IS...

UPDATED : FRI, NOVEMBER 13, 2015 @ 9:25 PM

Studying the expression level of RNA transcripts is often complicated by the
fact that many DNA sequences are...

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RNA FISH General science


RESEARCH HIGHLIGHT: BRINGING VISION RESEARCH INTO FOCUS

UPDATED : TUE, MARCH 21, 2023 @ 3:37 PM

Gene expression and molecular biology research in vision and ophthalmology
presents unique challenges to researchers...

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RNA FISH General science


FISH-ING FOR FUSIONS: A UNIQUE APPROACH TO FUSION GENE MRNA & PRE-MRNA DETECTION
IN CANCER

UPDATED : FRI, NOVEMBER 13, 2015 @ 10:27 PM

This past April, Biosearch attended the American Association of Cancer Research
(AACR) conference in Philadelphia,...

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qPCR General science


HOW MUCH IS YOUR QPCR ASSAY REALLY COSTING YOU?

UPDATED : FRI, NOVEMBER 13, 2015 @ 10:40 PM

In the setup of a qPCR experiment, one of the first decisions to make is which
detection method to use. This...

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RNA FISH General science


THE 4CS OF STELLARIS® RNA FISH BUFFERS

UPDATED : MON, NOVEMBER 16, 2015 @ 3:55 PM 

Buffers are often overlooked and taken for granted until the day comes when a
peculiar result is observed and its...

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Oligo synthesis and modifications General science


KNOW YOUR OLIGO MOD: PHOSPHOROTHIOATE BONDS

UPDATED : WED, MARCH 29, 2023 @ 10:56 AM

This post in our continuing series, “Know your oligo mod” will cover
phosphorothioate bonds, which are available for...

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qPCR General science


OPTIMISING MULTIPLEX COMPETITIVE QRT-PCR IN DIAGNOSTICS WITH BHQPLUS PROBES

UPDATED : MON, NOVEMBER 16, 2015 @ 5:30 PM

In a webinar linked below, Dr. James Willey describes a two colour fluorometric
assay for more robust quantitation...

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qPCR PCR-based genotyping General science


A SUCCESSFUL DUO FOR ACCURATE, SPEEDY, AND ECONOMICAL SNP GENOTYPING

UPDATED : MON, SEPTEMBER 19, 2022 @ 2:12 PM

Single Nucleotide Polymorphisms (SNPs) have been widely studied for over 15
years, and have applications in...

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Oligo synthesis and modifications General science


KNOW YOUR OLIGO MOD: METHYLENE BLUE

UPDATED : WED, MARCH 29, 2023 @ 10:56 AM

The chemical synthesis of oligonucleotides allows for the incorporation of a
wealth of modifications to an oligo...

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RNA FISH General science


UNRAVELING THE NEURAL WEB: STELLARIS® RNA FISH FOR NEUROSCIENCE RESEARCH

UPDATED : MON, SEPTEMBER 19, 2022 @ 2:14 PM

Neuroscience gene expression research can come with many hurdles, especially
when working with brain tissue or...

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qPCR General science


CHECK OUT OUR NEW WEBSITE QPCR DESIGN LAB @ QPCRDESIGN.COM

UPDATED : TUE, MARCH 28, 2023 @ 9:02 PM

Biosearch Technologies has launched qPCRdesign.com, a microsite targeted
specifically for your quantitative PCR...

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ABOUT LGC, BIOSEARCH TECHNOLOGIES

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