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* More from Allergan Aesthetics
* Patient Safety Information
* Important Safety Information
* For Healthcare Professionals

* BOTOX® COSMETIC
(onabotolinumtoxinA)
* KYBELLA®
(deoxycholic acid) injection 10mg/mL
* COOLSCULPTING®
* LATISSE®
(bimatoprost ophthalmic solution) 0.03%
* NATRELLE®
* SKINMEDICA®

* JUVÉDERM® Ultra XC
for Lip Augmentation
* JUVÉDERM® VOLBELLA® XC
for Lip Augmentation
* JUVÉDERM® VOLUMA® XC
for Cheek Augmentation
* JUVÉDERM® Ultra Plus XC
* JUVÉDERM® Ultra XC
for Facial Wrinkles and Folds
* JUVÉDERM® VOLBELLA® XC
for Undereye Hollows
* JUVÉDERM® VOLUMA® XC
for Chin Augmentation
* JUVÉDERM® VOLLURE® XC
* JUVÉDERM® Ultra
* JUVÉDERM® VOLUX® XC
*

U.S. Residents
* LEARN
* BEFORE & AFTER
* TREAT
* CHEEKS
* CHIN
* LINES
* LIPS
* JAWLINE
* UNDEREYES

* SAVINGS

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FIND A PROVIDER
FIND A SPECIALIST :
* LEARN
* BEFORE & AFTER
* TREAT
* TREAT
* CHEEKS
* CHIN
* LINES
* LIPS
* JAWLINE
* UNDEREYES
* SAVINGS
* More from Allergan Aesthetics
* BOTOX® COSMETIC
(onabotolinumtoxinA)
* KYBELLA®
(deoxycholic acid) injection 10mg/mL
* COOLSCULPTING®
* LATISSE®
(bimatoprost ophthalmic solution) 0.03%
* NATRELLE®
* SKINMEDICA®
* Patient Safety Information
* JUVÉDERM® Ultra XC
for Lip Augmentation
* JUVÉDERM® VOLBELLA® XC
for Lip Augmentation
* JUVÉDERM® VOLUMA® XC
for Cheek Augmentation
* JUVÉDERM® Ultra Plus XC
* JUVÉDERM® Ultra XC
for Facial Wrinkles and Folds
* JUVÉDERM® VOLBELLA® XC
for Undereye Hollows
* JUVÉDERM® VOLUMA® XC
for Chin Augmentation
* JUVÉDERM® VOLLURE® XC
* JUVÉDERM® Ultra
* JUVÉDERM® VOLUX® XC
* For Healthcare Professionals

U.S. Residents

SUBTLE OR PLUMP LIPS

WITH RESULTS LASTING UP TO 12 MONTHS WITH OPTIMAL TREATMENT

Actual patient treated with JUVÉDERM® VOLBELLA® XC in the lips. Results may
vary.

NATASHA

Cheeks treated with
JUVÉDERM® VOLUMA® XC
Lines treated with
JUVÉDERM® VOLLURE® XC
Lips treated with
JUVÉDERM® VOLBELLA® XC
Before After

NATASHA

Cheeks treated with
JUVÉDERM® VOLUMA® XC
Lines treated with
JUVÉDERM® VOLLURE® XC
Lips treated with
JUVÉDERM® VOLBELLA® XC
DRAG
DRAG
DRAG
DRAG
DRAG
DRAG

Actual patient. Results may vary. Unretouched photos taken before treatment and
1 month after treatment with 1.0 mL of JUVÉDERM® VOLUMA® XC in the cheeks, 1.0
mL of JUVÉDERM® VOLLURE® XC in the lines, and 1.0 mL of JUVÉDERM® VOLBELLA® XC
in the lips.

ASHLEY

Cheeks treated with
JUVÉDERM® VOLUMA® XC
Lines treated with
JUVÉDERM® VOLLURE® XC
Lips treated with
JUVÉDERM® VOLBELLA® XC
DRAG
DRAG
DRAG
DRAG
DRAG
DRAG

BRIDGET

Lines treated with
JUVÉDERM® VOLLURE® XC
Lips treated with
JUVÉDERM® VOLBELLA® XC
DRAG
DRAG
DRAG
DRAG
DRAG
DRAG

Actual patient. Results may vary. Unretouched photos taken before treatment and
1 month after treatment with 1.0 mL of JUVÉDERM® VOLLURE® XC in the lines, and
1.0 mL of JUVÉDERM® VOLBELLA® XC in the lips.

KELLY

Lines treated with
JUVÉDERM® Ultra XC
Lips treated with
JUVÉDERM® Ultra XC
DRAG
DRAG
DRAG
DRAG
DRAG
DRAG

Actual patient. Results may vary. Unretouched photos taken before treatment and
1 month after treatment with 1.2 mL of JUVÉDERM® Ultra XC in the lines, and 1.7
mL of JUVÉDERM® Ultra XC in the lips.

RACHEL

Lines treated with
JUVÉDERM® Ultra XC
Lips treated with
JUVÉDERM® Ultra XC
DRAG
DRAG
DRAG
DRAG
DRAG
DRAG

Actual patient. Results may vary. Unretouched photos taken before treatment and
1 month after treatment with 1.0 mL of JUVÉDERM® Ultra XC in the lines, and 0.9
mL of JUVÉDERM® Ultra XC in the lips.

JENNIFER

Lips treated with
JUVÉDERM® Ultra XC

DRAG
DRAG
DRAG
DRAG
DRAG
DRAG

Actual patient. Results may vary. Unretouched photos taken before treatment and
1 month after treatment with 1.65 mL of JUVÉDERM® Ultra XC in the lips.

KIM

Lips treated with
JUVÉDERM® Ultra XC
DRAG
DRAG
DRAG
DRAG
DRAG
DRAG

Actual patient. Results may vary. Unretouched photos taken before treatment and
1 month after treatment with 1.6 mL of JUVÉDERM® Ultra in the lips.

KRIS

Lips treated with JUVÉDERM® VOLBELLA® XC
DRAG
DRAG
DRAG
DRAG
DRAG
DRAG

Actual patient. Results may vary. Unretouched photos taken before treatment and
1 month after treatment with 1.5 mL of JUVÉDERM® VOLBELLA® XC in the lips.

ANNE

Lines treated with
JUVÉDERM® XC
Lips treated with
JUVÉDERM® Ultra XC
DRAG
DRAG
DRAG
DRAG
DRAG
DRAG

Actual patient. Results may vary. Unretouched photos taken before treatment and
1 month after treatment with 0.85 mL of JUVÉDERM® Ultra XC in the lips and 2.6
mL of JUVÉDERM® XC in the lips.

ERIN

Cheeks treated with
JUVÉDERM® VOLUMA® XC
Lines treated with
JUVÉDERM® XC
Lips treated with
JUVÉDERM® Ultra XC
DRAG
DRAG
DRAG
DRAG
DRAG
DRAG

Actual patient. Results may vary. Unretouched photos taken before treatment and
1 month after treatment with 1.0 mL of JUVÉDERM® VOLUMA® XC in the cheeks, 1.6
mL of JUVÉDERM® XC in the lines and 0.9 mL of JUVÉDERM® Ultra XC in the lips.

BRIDGHAM

Lips treated with
JUVÉDERM® VOLBELLA® XC
DRAG
DRAG
DRAG
DRAG
DRAG
DRAG

Actual patient. Results may vary. Unretouched photos taken before treatment and
1 month after treatment with 1.1 mL of JUVÉDERM® VOLBELLA® XC in the lips.

CLANCY

Lips treated with
JUVÉDERM® Ultra
DRAG
DRAG
DRAG
DRAG
DRAG
DRAG

Actual patient. Results may vary. Unretouched photos taken before treatment and
1 month after treatment with 1.2 mL of JUVÉDERM® Ultra in the lips.

TAMMY

Lips & lip lines treated with
JUVÉDERM® VOLBELLA® XC
DRAG
DRAG
DRAG
DRAG
DRAG
DRAG

Actual patient. Results may vary. Unretouched photos taken before treatment and
1 month after treatment with 2.05 mL of JUVÉDERM® VOLBELLA® XC in the lips & lip
lines.

LORNA

Lips treated with
JUVÉDERM® Ultra XC
Lines treated with
JUVÉDERM® XC
DRAG
DRAG
DRAG
DRAG
DRAG
DRAG

Actual patient. Results may vary. Unretouched photos taken before treatment and
1 month after treatment with 1.3 mL of JUVÉDERM® Ultra XC in the lips and 2.5 mL
of JUVÉDERM® XC in the lines.

MICHELLE

Lips treated with
JUVÉDERM® VOLBELLA® XC
DRAG
DRAG
DRAG
DRAG
DRAG
DRAG

Actual patient. Results may vary. Unretouched photos taken before treatment and
1 month after treatment with 1.2 mL of JUVÉDERM® VOLBELLA® XC in the lips.

DRAG
* BEFORE
*
*
*
*
* AFTER

*
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*
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*
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* ALL
* 20s
* 30s
* 40s

WHY JUVÉDERM®

JUVÉDERM® COLLECTION OF
FILLERS IS THE #1
CHOSEN DERMAL FILLER*

*December 2022 Provider Survey Data (n=938)

JUVÉDERM® VOLBELLA® XC
FILLER FOR LINES ABOVE THE LIPS

TOP 3 MOST RESEARCHED
MINIMALLY INVASIVE
COSMETIC TREATMENTS†

†RealSelf 2018 Aesthetics Trend Report

JUVÉDERM® FILLERS FAQ

Find answers to the most commonly asked questions about the JUVÉDERM® Collection
of Fillers.

JUVÉDERM® COLLECTION

CHEEKS

JUVÉDERM® VOLUMA® XC

CHIN

JUVÉDERM® VOLUMA® XC

LINES

JUVÉDERM® VOLLURE® XC
JUVÉDERM® ULTRA PLUS XC

LIPS

JUVÉDERM® VOLBELLA® XC
JUVÉDERM® ULTRA XC

JAWLINE

JUVÉDERM® VOLUX® XC

UNDEREYES

JUVÉDERM® VOLBELLA® XC
SELECT PRODUCT
Done
* SELECT PRODUCT
* JUVÉDERM® COLLECTION

* CHEEKS

JUVÉDERM® VOLUMA® XC

* CHIN

JUVÉDERM® VOLUMA® XC

* LINES

JUVÉDERM® VOLLURE® XC
JUVÉDERM® ULTRA PLUS XC

* LIPS

JUVÉDERM® VOLBELLA® XC
JUVÉDERM® ULTRA XC

* JAWLINE

JUVÉDERM® VOLUX® XC

* UNDEREYES

JUVÉDERM® VOLBELLA® XC

WHAT IS JUVÉDERM®?

JUVÉDERM® is the #1 chosen collection of hyaluronic acid fillers in the US*.
Each product in the JUVÉDERM® Collection of Fillers adds volume to a different
area of the face—without surgery. All JUVÉDERM® fillers are smooth,
crystal-clear gels that are administered by injection in your aesthetic
healthcare provider's office.

*December 2022 Provider Survey Data (n=938)

WHERE IS JUVÉDERM® USED?

Different formulations are approved to either volumize cheeks, smooth smile
lines, smooth lines around the mouth, plump the lips, define the chin, improve
the jawline, or improve the appearance of undereye hollows. The results are
long-lasting, and can be customized by your licensed specialist to help you
achieve your aesthetic goals.

The JUVÉDERM® Collection of Fillers are for adults over 21.

JUVÉDERM® VOLLURE® XC softens moderate to severe facial wrinkles and folds (eg,
nasolabial folds) by adding volume around the nose and mouth.

JUVÉDERM® VOLUMA® XC is for deep injection in the cheek area to correct
age-related volume loss and for augmentation of the chin region to improve the
chin profile.

JUVÉDERM® VOLBELLA® XC adds volume to the lips for a subtle plump, softens the
appearance of perioral lines, and improves the appearance of undereye hollows.

JUVÉDERM® ULTRA PLUS XC smooths moderate to severe facial wrinkles and folds
around your nose and mouth.

JUVÉDERM® ULTRA XC adds fullness and plumps lips as well as smooths and corrects
moderate to severe wrinkles and folds in adults.

JUVÉDERM® VOLUX® XC adds volume along the jawline area to improve jawline
definition in patients with moderate to severe loss. The added volume augments
the shape and structure of the lower face.

DOES JUVÉDERM® HAVE FDA APPROVAL?

Products in the JUVÉDERM® Collection are FDA approved and have been widely
studied. Numerous clinical studies have been completed globally evaluating the
safety and effectiveness of Vycross® technology fillers. Please see below for
Important Safety Information.

WHAT IS VYCROSS®? IS VYCROSS® THE SAME AS JUVÉDERM®?

Vycross® is the #1 chosen filler technology in the world. Vycross® is a
proprietary technology designed by Allergan Aesthetics for use in its JUVÉDERM®
Collection of hyaluronic acid (HA) fillers, including JUVÉDERM® VOLUMA® XC,
JUVÉDERM® VOLLURE® XC, JUVÉDERM® VOLBELLA® XC, and JUVÉDERM® VOLUX® XC. Vycross®
technology cross-links HA molecules to create a smooth and efficiently
cross-linked filler. All Vycross® fillers contain a small quantity of lidocaine
to decrease injection-site pain.

*December 2022 Provider Survey Data (n=938)

WHAT IS HYALURONIC ACID?

The JUVÉDERM® Collection of Fillers is made from hyaluronic acid (HA). HA is a
natural substance in the skin that delivers nutrients, helps the skin retain
moisture and softness. Each product in the JUVÉDERM® Collection of Fillers is
made from a modified form of HA.

WHAT IS THE TREATMENT EXPERIENCE LIKE?

Your aesthetic healthcare provider will take your medical history and provide a
facial analysis. Be prepared to discuss your aesthetic areas of concern. This is
not a surgical treatment. Actual treatment with JUVÉDERM® injectable gels can
take 15 minutes to 60 minutes, depending on which area of your face is being
treated.

DOES IT HURT?

JUVÉDERM® injectable gels labeled with "XC" contain pain-reducing lidocaine to
help manage pain or discomfort during the injection. You may also ask your
aesthetic healthcare provider about a topical numbing cream or ice to help
further minimize discomfort.

WHAT IS THE AVERAGE TREATMENT COST?

The cost not only includes the price of the product but, more importantly, the
skill and expertise of the specialist or healthcare professional who is
administering your treatment. Look for someone who is licensed and trained and
has experience treating patients with the JUVÉDERM® Collection. Be wary of
discount products or “cheap” JUVÉDERM® Collection treatments — if it sounds too
good to be true, it probably is.

It is more important to find an experienced specialist who will take the time to
understand your treatment goals and develop a treatment plan that is right for
you.

HOW CAN I SAVE ON TREATMENTS?

Join Allē, the new and improved loyalty program by the makers of JUVÉDERM®, for
savings on treatments within the JUVÉDERM® Collection. With Allē, you can earn
200 points for qualifying JUVÉDERM® treatments that you can redeem for savings
on future treatments.

Allē also rewards you for getting a variety of in-office treatments from other
brands, too. Then, redeem points for savings on your favorite Allergan
Aesthetics brands. Use points as you go, or store them in your Wallet for big
savings later. 100 Points = $10 toward qualifying products and treatments.

WHEN WILL I SEE RESULTS?

You will see results immediately/instantly.

HOW LONG DO RESULTS LAST?

Results may last one year to two years, with optimal treatment and depending on
the formula used and the area treated. Please read each product description to
see how long results last with each formula and treatment area, based on what
was observed in clinical studies.

ARE THERE ANY REASONS I SHOULDN’T RECEIVE JUVÉDERM® INJECTABLE GEL FILLERS?

Do not receive JUVÉDERM® injectable gel fillers if you have a history of severe
allergic reactions (anaphylaxis), or if you are allergic to lidocaine or the
proteins (Gram-positive bacterial proteins) used to make hyaluronic acid (HA) in
JUVÉDERM® injectable gel fillers.

DO JUVÉDERM® FILLERS HAVE AN ESTABLISHED SAFETY PROFILE?

JUVÉDERM® fillers have established safety profiles. The safety and effectiveness
of JUVÉDERM® fillers have been evaluated in numerous clinical studies worldwide.

IS TREATMENT PERMANENT?

Treatment with JUVÉDERM® fillers is not permanent. Depending on the JUVÉDERM®
filler used and the treatment area, results may last one year to two years with
optimal treatment.

WHAT ARE THE COMMON SIDE EFFECTS?

The most common side effects are redness, swelling, pain, and tenderness.
Minimize exercise, sun or heat exposure, and alcoholic beverages within the
first 24 hours following treatment to avoid worsening these side effects. Talk
to your licensed specialist about post-care instructions following treatment and
please see below for more Important Safety Information.

WHAT IS JUVÉDERM® VOLUMA® XC?

As you age, the cheeks may flatten and the skin may begin to sag. This is caused
by natural loss of volume in the cheek area, or what the experts call
age-related midface volume loss. JUVÉDERM® VOLUMA® XC adds volume beneath the
skin's surface, which provides lift and contour to the cheek area.

HOW LONG DOES JUVÉDERM® VOLUMA® XC LAST?

JUVÉDERM® VOLUMA® XC provides natural-looking and long-lasting results that last
up to 2 years with optimal treatment.

WHAT ARE THE POTENTIAL SIDE EFFECTS OF JUVÉDERM® VOLUMA® XC?

The most common side effects included temporary reactions at the treatment site
such as tenderness, swelling, firmness, lumps/bumps, bruising, pain, redness,
discoloration, and itching. Side effects were moderate (uncomfortable), and
generally lasted 2 to 4 weeks. As with all skin injection procedures, there is a
risk of infection.

HOW DOES JUVÉDERM® VOLUMA® XC WORK?

As you age, the cheek area loses its youthful shape. The cheeks flatten out and
the skin may begin to sag. JUVEDERM® VOLUMA® XC injectable gel is designed to
temporarily reverse these signs of aging. It is a gel that is injected into the
cheek area to lift the skin. It temporarily adds volume to the cheek area and
results in a smoother contour and more youthful appearance to the face.

WHAT IS JUVÉDERM® VOLUMA® XC?

JUVÉDERM® VOLUMA® XC injectable gel is designed for deep injection for
augmentation of the chin region to improve the chin profile. Adding volume to
the chin area creates shape and definition for adults over 21 years of age.

HOW LONG DOES JUVÉDERM® VOLUMA® XC LAST?

JUVÉDERM® VOLUMA® XC provides results that can last up to 1 year in the chin
with optimal treatment.

WHAT ARE THE POTENTIAL SIDE EFFECTS OF JUVÉDERM® VOLUMA® XC?

For chin augmentation, the most common side effects were temporary reactions at
the treatment site, such as tenderness, firmness, swelling, pain, lumps/bumps,
redness, itching and discoloration. Most of the side effects were mild in
nature, and generally resolved in 2-4 weeks. As with all skin-injection
procedures, there is a risk of infection.

HOW DOES JUVÉDERM® VOLUMA® XC WORK?

JUVÉDERM® VOLUMA® XC is injected into the chin area to increase chin projection.
It temporarily adds volume to the chin area and results in an improved chin
shape. The addition of lidocaine helps to improve the comfort of the injection
by reducing sensitivity to pain.

WHAT IS JUVÉDERM® VOLLURE® XC?

JUVÉDERM® VOLLURE® XC is injected into the areas of facial tissue where moderate
to severe facial wrinkles and folds occur. These are the deep lines that extend
from the corners of the mouth to the chin—also known as marionette lines, as
well as the deep lines and wrinkles that extend from the sides of the nose to
the corners of the mouth—also known as nasolabial folds. Nasolabial folds are
commonly referred to as smile or laugh lines. JUVÉDERM® VOLLURE® XC is designed
to temporarily correct facial wrinkles for a smoother appearance to the face for
adults over the age of 21.

HOW LONG DOES JUVÉDERM® VOLLURE® XC LAST?

The clinical study demonstrated JUVÉDERM® VOLLURE® XC lasts up to 18 months with
optimal treatment.

WHAT ARE THE POTENTIAL SIDE EFFECTS OF JUVÉDERM® VOLLURE® XC?

The most common side effects included firmness, swelling, tenderness to touch,
lumps/bumps, redness, pain, bruising, itching, and discoloration at the
injection site. These side effects were usually mild or moderate in nature
(causing little to some discomfort and impact on daily activities) and lasted 14
days or less.

HOW DOES JUVÉDERM® VOLLURE® XC WORK?

Over time, wrinkles develop on your face, and nasolabial folds may become more
visible. JUVÉDERM® VOLLURE® XC is designed to temporarily add volume to the
facial wrinkles for a smoother appearance to the face. The lidocaine in the gel
improves the comfort of the injection by reducing sensitivity to pain.

WHAT IS JUVÉDERM® ULTRA PLUS XC?

First approved by the FDA in 2006, JUVÉDERM® Ultra Plus XC corrects moderate to
severe facial wrinkles and folds, such as the parentheses lines or "smile/laugh
lines" around the nose and mouth, also known as nasolabial folds. JUVÉDERM®
Ultra Plus XC is injected into areas of facial tissue where moderate to severe
facial wrinkles and folds occur to temporarily add volume to the skin, which may
give the appearance of a smoother surface.

HOW LONG DOES JUVÉDERM® ULTRA PLUS XC LAST?

JUVÉDERM® Ultra Plus XC lasts up to one year with optimal treatment.

WHAT ARE THE POTENTIAL SIDE EFFECTS OF JUVÉDERM® ULTRA PLUS XC?

The most commonly reported side effects of JUVÉDERM® Ultra Plus XC injectable
gels were temporary injection-site redness, swelling, pain/tenderness, firmness,
lumps/bumps, bruising, itching, and discoloration. They were predominantly mild
or moderate in nature and lasted 7 days or less.

HOW DOES JUVÉDERM® ULTRA PLUS XC WORK?

JUVÉDERM® Ultra Plus XC is injected into areas of facial tissue where moderate
to severe facial wrinkles and folds occur to temporarily add volume to the skin,
which may give the appearance of a smoother surface.

WHAT IS JUVÉDERM® VOLBELLA® XC?

JUVÉDERM® VOLBELLA® XC injectable gel is for injection into the lips for lip
augmentation and for correction of perioral lines (lines around the mouth),
often called lipstick lines, vertical lip lines, or lip wrinkles in adults over
the age of 21.

HOW LONG DOES JUVÉDERM® VOLBELLA® XC LAST?

JUVÉDERM® VOLBELLA® XC lasts up to 1 year, with optimal treatment.

WHAT ARE THE POTENTIAL SIDE EFFECTS OF JUVÉDERM® VOLBELLA® XC?

The most common side effects included temporary reactions at the treatment site
such as tenderness, swelling, firmness, lumps/bumps, bruising, pain, redness,
discoloration, and itching. Side effects were mild or moderate (uncomfortable)
and generally lasted 30 days or less.

HOW DOES JUVÉDERM® VOLBELLA® XC WORK?

JUVÉDERM® VOLBELLA® XC is a crystal-clear gel that is injected directly into and
around the lips using an ultra-fine needle to temporarily plump the lips for lip
augmentation and to smooth the appearance of lines around the mouth. The
lidocaine gel improves the comfort of the injection by reducing sensitivity to
pain.

WHAT IS JUVÉDERM® ULTRA XC?

JUVÉDERM® Ultra XC is an injectable gel that temporarily adds more fullness and
plumps thin lips—whether your lips have thinned over time or you simply want
fuller lips—in adults over the age of 21.

HOW LONG DOES JUVÉDERM® ULTRA XC LAST?

JUVÉDERM® Ultra XC lasts up to one year, with optimal treatment.

WHAT ARE THE POTENTIAL SIDE EFFECTS OF JUVÉDERM® ULTRA XC?

For lip augmentation, most side effects were mild or moderate in nature with
duration of 14 days or less. The most common side effects were temporary
reactions at the treatment site such as tenderness, swelling, firmness,
lumps/bumps, and bruising.

HOW DOES JUVÉDERM® ULTRA XC WORK?

JUVEDERM® Ultra XC is a crystal-clear gel that is injected directly into and
around the lips using a small needle to temporarily add the desired range of
fullness for lip enhancement in adults over the age of 21. The lidocaine in the
gel improves the comfort of the injection by reducing sensitivity to pain.

WHAT IS JUVÉDERM® VOLUX® XC?

JUVÉDERM® VOLUX® XC is an injectable gel designed to improve jawline definition
in patients with moderate to severe loss of jawline definition. Adding volume to
improve the shape and structure of the lower face helps provide smooth,
long-lasting definition in the jawline for adults over 21 years of age.

HOW LONG DOES JUVÉDERM® VOLUX® XC LAST?

JUVÉDERM® VOLUX® XC lasts up to 1 year, with optimal treatment.

WHAT ARE THE POTENTIAL SIDE EFFECTS OF JUVÉDERM® VOLUX® XC?

Most side effects were mild or moderate in nature with duration of 14 days or
less—35% of side effects lasted up to 30 days. The most common side effects were
temporary reactions at the treatment site, such as tenderness, lumps/bumps,
pain, swelling, firmness, bruising, redness, itching, and discoloration. As with
all skin-injection procedures, there is a risk of infection.

HOW DOES JUVÉDERM® VOLUX® XC WORK?

JUVÉDERM® VOLUX® XC is a crystal-clear gel that is injected into the jaw to
improve jawline definition. It temporarily adds volume to augment the shape and
structure of the lower face and results in improved jawline definition in adults
over the age of 21. The lidocaine in the gel improves the comfort of the
injection by reducing sensitivity to pain.

WHAT IS JUVÉDERM® VOLBELLA® XC?

JUVÉDERM® VOLBELLA® XC is an injectable gel that adds volume to improve the
appearance of undereye hollowing. Undereye hollows are depressed, sunken, or
hollow areas below the eyes that contribute to a tired-looking appearance.

HOW LONG DOES JUVÉDERM® VOLBELLA® XC LAST?

JUVÉDERM® VOLBELLA® XC lasts up to 1 year in the undereye hollows with optimal
treatment.

WHAT ARE THE POTENTIAL SIDE EFFECTS OF JUVÉDERM® VOLBELLA® XC?

Most side effects were mild or moderate in nature and generally resolved within
30 days. The most common side effects were temporary reactions at the treatment
site, such as tenderness, bruising, swelling, lumps/bumps, redness, pain,
firmness, discoloration, or itching. As with all skin-injection procedures,
there is a risk of infection.

HOW DOES JUVÉDERM® VOLBELLA® XC WORK?

JUVÉDERM® VOLBELLA® XC is a crystal-clear gel that is injected into the undereye
area to improve the appearance of undereye hollows. It temporarily restores lost
volume to the undereye hollows to create a smooth transition from the undereye
area to the cheek area, with results that last up to 1 year with optimal
treatment. The addition of lidocaine helps to improve the comfort of the
injection by reducing sensitivity to pain.

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IMPORTANT SAFETY INFORMATION

Do not use these products if you have a history of multiple severe allergies or
severe allergic reactions (anaphylaxis), if you are allergic to lidocaine or the
Gram-positive bacterial proteins used in these products, or if you have had
previous allergic reactions to hyaluronic acid fillers.

APPROVED USES

JUVÉDERM® VOLUX® XC injectable gel is for deep injection to improve moderate to
severe loss of jawline definition in adults over the age of 21.

JUVÉDERM® VOLUMA® XC injectable gel is for deep injection in the cheek area to
correct age-related volume loss and for augmentation of the chin region to
improve the chin profile in adults over 21.

JUVÉDERM® VOLLURE® XC, JUVÉDERM® Ultra Plus XC, and JUVÉDERM® Ultra XC
injectable gels are for injection into the facial tissue for the correction of
moderate to severe facial wrinkles and folds, such as nasolabial folds.
JUVÉDERM® VOLLURE® XC injectable gel is for adults over 21.

JUVÉDERM® Ultra XC injectable gel is also for injection into the lips and
perioral area for lip augmentation in adults over 21.

JUVÉDERM® VOLBELLA® XC injectable gel is for injection into the lips for lip
augmentation and correction of perioral lines, and for injection into the
undereye hollows to improve the appearance of undereye hollows in adults over
the age of 21.

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IMPORTANT SAFETY INFORMATION

APPROVED USES

JUVÉDERM® VOLUX® XC injectable gel is for deep injection to improve moderate to
severe loss of jawline definition in adults over the age of 21.

JUVÉDERM® Ultra XC injectable gel is also for injection into the lips and
perioral area for lip augmentation in adults over 21.

JUVÉDERM® INJECTABLE GEL FILLERS IMPORTANT INFORMATION

ARE THERE ANY REASONS WHY I SHOULD NOT RECEIVE ANY JUVÉDERM® FORMULATION?

WHAT WARNINGS SHOULD MY DOCTOR ADVISE ME ABOUT?

* One of the risks with using dermal fillers is the unintentional injection
into a blood vessel. The chances of this happening are very small, but if it
does happen, the complications can be serious and may be permanent. These
complications, which have been reported for facial injections, can include
vision abnormalities, blindness, stroke, temporary scabs, or permanent
scarring of the skin. Most of these events are irreversible.

* If you have changes in your vision, signs of a stroke (including sudden
difficulty speaking, numbness or weakness in your face, arms or legs,
difficulty walking, face drooping, severe headache, dizziness, or confusion),
white appearance of the skin, or unusual pain during or shortly after
treatment, you should notify your health care practitioner immediately.

* The use of dermal fillers where skin sores, pimples, rashes, hives, cysts, or
infections are present should be postponed, as this may delay healing or make
skin problems worse

* The effectiveness of removal of any dermal filler has not been studied.

WHAT PRECAUTIONS SHOULD MY DOCTOR ADVISE ME ABOUT?

* JUVÉDERM® VOLBELLA® XC should only be injected into undereye hollows by
doctors who have completed the necessary training for this treatment area. To
find a doctor, visit Juvederm.com/find-a-specialist. Doctors who complete the
training will be listed with a symbol

* The safety of these products for use during pregnancy or while breastfeeding
has not been studied

* The safety of JUVÉDERM® VOLUMA® XC has not been studied in patients under 35
years or over 65 years for cheek augmentation, or under 22 years and over 80
years for chin augmentation. The safety of JUVÉDERM® VOLUX® XC, JUVÉDERM®
VOLLURE® XC and JUVÉDERM® VOLBELLA® XC has not been studied in patients under
22 years, and the safety of JUVÉDERM® Ultra Plus XC and JUVÉDERM® Ultra XC
has not been studied in patients under 18 years

* The safety and effectiveness of treatment with JUVÉDERM® products in
anatomical regions outside of their approved uses have not been established
in clinical studies

* If you have a history of excessive scarring (thick, hard scars) or
pigmentation disorders, treatment in these patients has not been studied and
may result in additional scars or changes in pigmentation

* If you are planning other procedures including laser treatments or a chemical
peel, there is a possible risk of inflammation at the treatment site if these
procedures are performed closely before or after JUVÉDERM® injectable gel
treatment

* Tell your doctor if you are on therapy used to reduce your body’s natural
defense system (such as steroids, chemotherapy, and medicines to treat
autoimmune diseases, HIV, and AIDs), as these may increase your risk of
infection; and medications that can prolong bleeding (such as aspirin,
ibuprofen, or other blood thinners), as these may result in increased
bruising or bleeding at the injection site.

* Avoid applying makeup for 12 hours after treatment and minimize strenuous
exercise, exposure to extensive sun or heat, and alcoholic beverages within
the first 24 hours following treatment, as these may cause temporary redness,
swelling, and/or itching at the injection site

* JUVÉDERM® VOLUMA® XC was not studied in patients with significant loose skin
of the chin, neck, or jaw

* The effect of JUVÉDERM® VOLUMA® XC injection into the chin on facial hair
growth has not been studied

* Patients who experience skin injury near the site of JUVÉDERM® VOLUMA® XC
injection may be at a higher risk for adverse events

* Tell your doctor if you have already been injected with dermal fillers in the
same area as the one(s) you are about to be treated for. This information
helps your doctor decide when and whether you should get treatment

WHAT ARE POSSIBLE SIDE EFFECTS OF TREATMENT?

The most commonly reported side effects with JUVÉDERM® injectable gels were
redness, swelling, pain, tenderness, firmness, lumps/bumps, bruising,
discoloration, and itching. For JUVÉDERM® VOLBELLA® XC, dryness was also
reported.

These side effects are consistent with other facial injection procedures and
most will resolve within 30 days. Your doctor may choose to treat side effects
persisting longer with antibiotics, steroids, or hyaluronidase (an enzyme that
breaks down hyaluronic acid).

As with all skin injection procedures, there is a risk of infection.

To report a side effect with any product in the JUVÉDERM® Collection, please
call the Allergan® Product Support Department at 1-877-345-5372. Please also
visit Juvederm.com or talk to your doctor for more information.

Products in the JUVÉDERM® Collection are available only by a licensed physician
or properly licensed practitioner.

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© 2023 AbbVie. All rights reserved. JUVÉDERM® and its design are trademarks of
Allergan Holdings France SAS, an AbbVie company, or its affiliates. Allē and its
design are service marks Allergan, Inc., an AbbVie company. All other trademarks
are the property of their respective owners. JUV105480-v17 04/23

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