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Tuesday, May 28 2024
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Home/Health News/Research says pomegranates could offer a solution to fatty
liver disease
Health News


RESEARCH SAYS POMEGRANATES COULD OFFER A SOLUTION TO FATTY LIVER DISEASE

admin8 hours ago
0 37 2 minutes read


Credit: Pixabay/CC0 Public Domain




Researchers at Edith Cowan University (ECU) are investigating the effects
ellagic acid, an antioxidant found in some fruits and vegetables, could have on
halting and potentially reversing the damage caused by fatty liver disease.

Non-alcoholic fatty liver disease (NAFLD) is the physiological manifestation of
obesity in the liver. The prevalence of NAFLD has increased from 25.24% in 2015
to 29.38% in 2021, and this condition now accounts for 45.8% of all cases of
chronic-liver-disease-related deaths worldwide.

There currently exists no treatment for the long-term management of NAFLD;
however, dietary interventions have been investigated for the treatment of this
disease, including several polyphenolic compounds such as ellagic acid.

ECU researcher Dr. Lois Balmer and Ph.D. student Mrs. Tharani Senavirathna noted
that ellagic acid, which is found in a variety of food such as raspberries,
pomegranate, blackberries, and pecan nuts, is widely recognized for its
antioxidant properties, but also exhibits anti-inflammatory, antifibrotic and
anticancer properties.

The paper is published in the journal Antioxidants.

“Ellagic acid stands out as a remarkable polyphenolic compound, possessing a
wide range of pharmacological properties that hold promise in treating various
chronic diseases, including NAFLD.

“Due to its multifaceted biological effects, edible plants containing ellagic
acid, and its derivatives are recognized as valuable functional foods for
enhancing human health. Moreover, there is evidence suggesting that ellagic
acid, when combined with other antioxidant nutraceuticals, exhibits a
synergistic therapeutic effect, making it a potential candidate for combination
therapy.”

Mrs. Senavirathna was involved in a previously undertaken pilot study
investigating the effects of several polyphenolic compounds on NAFLD, with
ellagic acid showing the most promise in reducing inflammation.

A larger study is now under way which will also investigate at which point of
the illness treatment would be ineffective to reverse damage to the liver.

More information:
Tharani Senavirathna et al, Unlocking the Therapeutic Potential of Ellagic Acid
for Non-Alcoholic Fatty Liver Disease and Non-Alcoholic Steatohepatitis,
Antioxidants (2024). DOI: 10.3390/antiox13040485



Provided by
Edith Cowan University








Citation:
Research says pomegranates could offer a solution to fatty liver disease (2024,
May 27)
retrieved 27 May 2024
from
https://medicalxpress.com/news/2024-05-pomegranates-solution-fatty-liver-disease.html

This document is subject to copyright. Apart from any fair dealing for the
purpose of private study or research, no
part may be reproduced without the written permission. The content is provided
for information purposes only.









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Disease Fatty Liver Offer Pomegranates Research Solution
admin8 hours ago
0 37 2 minutes read

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