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NIH INSPECTOR GENERAL FINDS MORE THAN HALF OF CLINICAL TRIALS DURING COVID ‘DID
NOT COMPLY’ WITH FEDERAL REQUIREMENTS

 * by Kyle Becker
 * August 19, 2022


 * 
 * 
 * 

The National Institutes of Health’s Office of the Inspector General has found
that more than half the clinical trials funded in response to the Covid-19
pandemic did not comply with federal guidelines.

The OIG report, which was released earlier this week, sheds light on the lax
approach that the nation’s premier health institutes took to ensure that the
clinical trials met the highest standards for transparency and timely reporting.


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“We reviewed all 72 NIH-funded Intramural and Extramural clinical trials for
which Federal law and NIH policy required the results to be reported in calendar
year 2019 or 2020,” the NIH’s Inspector General stated. “To determine whether
responsible parties complied with reporting requirements, we compared the date
the results should have been submitted with the date they were submitted. We
also determined whether NIH posted the clinical trial results submitted by the
responsible parties to ClinicalTrials.gov within 30 days of the submission
date.”

The NIH’s IG found that more than half the clinical trials did not meet the
requisite federal reporting guidelines, either by failing to meet the deadline
or by not reporting the results at all. The Table summarizes the number of
clinical trials requiring results to be submitted in 2019 or 2020 that were
submitted on time, late, or not submitted at all.



“NIH did not ensure that all NIH-funded Intramural and Extramural clinical
trials complied with Federal reporting requirements for responsible parties to
submit the results of clinical trials to ClinicalTrials.gov,” the IG found.

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“The noncompliance with Federal reporting requirements occurred because NIH did
not have adequate procedures for ensuring that responsible parties submitted the
results of clinical trials, took limited enforcement action when there was
noncompliance, and continued to fund new research of responsible parties that
had not submitted the results of their completed clinical trials,” the IG said.
“For the 47 NIH-funded clinical trials in which the responsible party submitted
their results (35 submitted on time and 12 submitted late) NIH complied with the
Federal reporting requirements to post the results to ClinicalTrials.gov.”

The IG’s striking report follows upon the Director of the Centers for Disease
Control and Prevention admitting that the agency failed to achieve its results
during the Covid-19 pandemic and calling for sweeping reorganization.

“To be frank, we are responsible for some pretty dramatic, pretty public
mistakes, from testing to data to communications,” she said in a video address
given to the CDC’s roughly 11,000 employees.

“Her admission of the agency’s failings came after she received the findings of
an examination she ordered in April amid scathing criticism of the C.D.C.’s
performance,” WSJ reported on the confession. “The report itself was not
released; an agency official said it was not yet finished but would be made
public soon.”

If the Inspector General’s report is any indication, a full report isn’t likely
to come out in public anytime soon, if it comes out at all.


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