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Motilium
(Active Ingredient: Domperidone)

Motilium is used for stopping feelings of sickness (nausea) and being sick
(vomiting) in adults and children. It is also used for relieving stomach
discomfort, fullness or bloating and regurgitation of stomach contents (reflux
or heartburn) in adults.
Other names for this medication:
Aciban-dsr, Adzole-dm, Agilam, Apentral, Apuldon, Arcelenan, Atidon, Avizol-d,
Avomit, Benzilum, Bipéridys, Bompy, Canozol-d, Cilroton, Cinet, Cobaperidon,
Costi, Cosy, Coszol-d, Dalic, Dany, Deflux, Degut, Depam, Diocid-d, Docivin,
Dolium, Dombaz, Domedon, Domepraz, Domerdon, Dometa, Dometic, Domezol, Domilin,
Domilux, Domin, Dominal, Dominat, Dompan, Domped, Dompel, Dompenyl, Domper,
Domperdone, Domperidona, Domperidoni maleas, Domperidonmaleat, Domperidonum
Show all

Analogs of Motilium:
Motilium
Motilium 10mg

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 * Product description
 * Safety information
 * Side effects

 * INDICATIONS
   
   Motilium is indicated for:
   
   -         delayed gastric emptying of functional origin with
   gastro-oesophageal reflux and/or dyspepsia;
   
   -         control of nausea and vomiting of central or local origin;
   
   -         as an anti-emetic in patients receiving cytostatic and radiation
   therapy;
   
   -         facilitates radiological examination of the upper gastro-intestinal
   tract.
   
    INSTRUCTIONS 
   
   Use Motilium as directed by your doctor.
   
   * Take Motilium by mouth before meals.
   * If you miss a dose of Motilium, take it as soon as possible. If it is
     almost time for your next dose, skip the missed dose and go back to your
     regular dosing schedule. Do not take 2 doses at once.
   
   DOSAGE
   
   Acute conditions (mainly nausea, vomiting, hiccup)
   
   Adults: Two tablets (20 mg) 3 to 4 times per day, 15 to 30 minutes before
   meals and, if necessary, before retiring.
   Children 5 to 12 years old: One tablet (10 mg) 3 to 4 times per day, 15 to
   30 minutes before meals and, if necessary, before retiring.
   
   
   Chronic conditions (mainly dyspepsia)
   
   Adults: One tablet (10 mg) taken 3 times per day, 15 to 30 minutes before
   meals and, if necessary, before retiring. The dosage may be doubled.
    Children 5 to 12 years: ½ tablet (5 mg) 3 to 4 times per day, 15 to 30
   minutes before meals and if necessary, before retiring.
   
   This formulation is not suited for children under the age of 5 years, but for
   this group of patients the suspension is available. Motilium tablets are not
   suitable for children weighing less than 35kg.
   
   Motilium should be used with caution in patients with renal impairment or in
   those at risk of fluid retention. In patients with severe renal insufficiency
   ( serum creatinine more than 6 mg/100 mL, ie. more than 0,6 mmol/L) the
   elimination half-life of domperidone was increased from 7,4 to 20,8 hours.
   The dosing frequency should be reduced to once or twice daily, depending on
   the severity of impairment, and the dose may need to be reduced. Patients on
   prolonged therapy should be reviewed regularly.
   
   Ask your health care provider any questions you may have about how to use
   Motilium.
   
   STORAGE
   
   Store Motilium between 68 and 77 degrees F (20 and 25 degrees C). Protect
   from heat, light, and moisture. Do not store in the bathroom. Keep Motilium
   out of the reach of children and away from pets.
   
   MORE INFO:
   
   Active Ingredient: Domperidone.
   
   Motilium tablets contain lactose and may be unsuitable for people with
   lactose intolerance, glucose/galactose malabsorption or a genetic disorder
   leading to accumulation of galactose in the blood (galactosaemia).

 * Do NOT use Motilium if:
   
   * you are allergic to any ingredient in Motilium
   * you are pregnant, planning to become pregnant, or become pregnant while
     taking Motilium
   * you are breast-feeding.
   
   Contact your doctor or health care provider right away if any of these apply
   to you.
   
   Some medical conditions may interact with Motilium. Tell your doctor or
   pharmacist if you have any medical conditions, especially if any of the
   following apply to you:
   
   * if you are pregnant, planning to become pregnant, or are breast-feeding
   * if you are taking any prescription or nonprescription medicine, herbal
     preparation, or dietary supplement
   * if you have allergies to medicines, foods, or other substances.
   
   Not to be used in
   
   * Cancer of the pituitary gland resulting in over-production of the hormone
     prolactin (prolactinoma).
   * Conditions in which stimulating movement through the stomach could be
     harmful, for example if there is bleeding, an abnormal hole (perforation)
     or a blockage in the stomach or intestines.
   * Decreased liver function.
   
   Some medicines may interact with Motilium. Tell your health care provider if
   you are taking any other medicines. The following medicines may oppose the
   stimulating effect of domperidone on the gut and so could make it less
   effective:
   
   * antimuscarinic medicines, such as antispasmodics (eg atropine, hyoscine,
     propantheline), medicines for urinary incontinence (eg oxybutynin,
     flavoxate, tolterodine, propiverine, trospium), or antimuscarinics for
     Parkinson's (eg procyclidine, trihexyphenidyl, orphenadrine)
   * strong opioid painkillers, eg morphine, codeine.
   
   This may not be a complete list of all interactions that may occur. Ask your
   health care provider if Motilium may interact with other medicines that you
   take. Check with your health care provider before you start, stop, or change
   the dose of any medicine.
   
   
   IMPORTANT SAFETY INFORMATION:
   
   Always inform your doctor if you are pregnant or planning a pregnancy, before
   using any medicine.
   
   * The safety of this medicine for use during pregnancy has not been
     established. It should not be used in pregnant women unless the potential
     benefits to the mother outweigh any risks to the developing baby. It should
     only be used if the medicine is considered essential by your doctor.  
   * This medicine passes into breast milk in very small amounts that are not
     expected to be harmful to a nursing infant. However, the medicine is not
     recommended for use in women who are breastfeeding unless the potential
     benefit to the mother outweighs any risks to the nursing infant.

 * Medicines and their possible side effects can affect individual people in
   different ways. The following are some of the side effects that are known to
   be associated with this medicine. Just because a side effect is stated here
   does not mean that all people using this medicine will experience that or any
   side effect.
   
   Rare (affect between 1 in 1000 and 1 in 10,000 people)
   
   * Increased level of prolactin (milk producing hormone) in the blood
     (hyperprolactinaemia). Sometimes this can lead to symptoms such as abnormal
     enlargement of breasts in men (gynaecomastia), abnormal production of
     breast milk in men and women, or stopping of menstrual periods in women.
   * Decreased sex drive in men.
   
   Very rare (affect less than 1 in 10,000 people)
   
   * Stomach cramps.
   * Diarrhoea.
   * Itchy nettle-type rash (urticaria).
   * Abnormal or uncontrolled movements of the hands, legs, face, eyes, neck or
     tongue, for example tremor, twitching or stiffness (extrapyramidal
     effects). Consult a doctor straight away if you notice any symptoms like
     this.
   * Allergic reaction.
   
   This is not a complete list of all side effects that may occur. If you have
   questions about side effects, contact your health care provider.

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