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WHAT IS THC-O? EFFECTS & BENEFITS OF THE HEMP-DERIVED CANNABINOID

 * Understanding THC-O
 * Producing THC-O
 * Should You Make THC-O at Home?

> THC-O is a cannabinoid like CBD, CBC, and many others and is also a THC
> analog. Unlike many natural THC variants, it is synthetic and prepared by
> introducing acetate anhydride to delta-8-free CBD extract. Is THCO stronger
> than Delta 9? It is more potent than delta-8 and delta-9 and may have the same
> effects as these THC variants in low amounts but becomes more psychoactive in
> high dosages.
> 
> THC, the psychoactive cannabinoid, has many variants, with THC-O being one of
> them. THC-O is a psychedelic chemical compound in cannabis that’s synthesized
> from CBD. Of course, it occurs naturally but to make it THC-O that people can
> take advantage of, it has to be synthesized from delta-8- free CBD using
> acetate anhydride. Since it is more potent than delta-9 and delta-8, it is
> taken in small amounts to realize the same effects. Higher dosages of this
> cannabinoid lead to high psychoactive effects and might even be immobilized.
> Here is all you need to know about THC-O.


UNDERSTANDING THC-O

THC-O bears THC as part of its name, showing that it is somewhat related to the
psychoactive THC, responsible for the ‘high’ effects in weed (Schlienz et al.,
2018). Simply put, THC-O is a man-made cannabinoid that resembles THC in
chemical structure. Being a cannabinoid from hemp plants, you expect it to be
more natural. However, since it cannot be extracted directly and requires human
intervention, it is more synthetic.


PRODUCING THC-O

THC-O is synthetic and cannot make it as a compound until man intervenes. How is
it produced? Its production process is dangerous and may also make the
cannabinoid toxic. Unlike other THC homologs produced by chromatography
techniques, THC-O is produced with the intervention of acetate anhydride. It
starts with the extraction of CBD through high pressure and appropriate
solvents. The next step involves removing delta-8 THC from CBD, making a
delta-8-free non-psychoactive CBD, as Massi et al. (2006) described CBD. The
next step involves introducing acetate anhydride to the CBD extract, after which
you make THC-O.


SHOULD YOU MAKE THC-O AT HOME?

The internet is full of ideas and since the Covid-19 left people mostly indoors,
many like exploring new ideas, even working out their ways with recipes. Can you
try making THC-O at home? While it is possible to do so, it is a dangerous
process that you should not try. Acetate anhydride, the compound used in making
THC-O from the delta-8-free CBD, is highly flammable. Consequently, the process
may result in a fire; hence you should not attempt it at home. Rather, you can
consider trusted sources when shopping for THC-O products.


HOW DOES THC-O MAKE YOU FEEL?

It is worth noting that THC-O is a stronger variant of THC and happens to be as
3 times as strong as delta- 9 and 5 times as potent as delta-8. Of course, being
a THC analog, you expect it to be psychoactive since studies, including Schlienz
et al. (2018), found THC psychoactive. Still, the psychoactive effects of THC
are more pronounced in THC-O because the latter is more potent. Therefore, when
consumed in similar amounts as delta- 9 THC, it leads to a higher form of the
‘high’ effects, leaving a person feeling more stoned.


USE SMALLER DOSAGES WITH THC-O

Since THC-O is more potent than the standard THC, i.e., delta-9 THC, you only
need to use smaller dosages to attain the high effects. If you want to have
everything in control and not let the ‘high’ effect overwhelm you, you do well
to consider smaller dosages for THC-O. There is not so much on THC-O as a
compound, but anecdotal evidence shows that smaller dosages are enough to
produce the same effects of THC. Besides, you also want to keep it low to avoid
the side effects of THC.


LIMITED STUDIES ON THC-O

Unfortunately, there are limited studies on THC-O. Most research papers referred
to in the case of THC-O do not offer enough scientific evidence for the claims
linked to the cannabinoid, and they mostly refer to anecdotal cases. As such, we
have yet to learn much about THC-O. So far, we know that it is synthetic and
cannot make it a compound unless with human intervention. It is also clear that
it is stronger than other THC variants, and its high dosages do not go well with
people.


IS THC-O SAFE?

The cannabis space has many cannabinoids, and one common question across all of
them is the safety concern. Is THC-O safe? Generally, studies related to THC-O
are limited, and not so much is available on the safety profile of the synthetic
cannabinoid. However, being that THC-O is only made by adding acetate anhydride
to CBD, you need to take it slow; the solvent may leave traces in the final
product, compromising the safety of THC-O. Sadly, the cannabis space is largely
unregulated, leaving a leeway for cannabis brands to deal in substandard
products. As such, you can only hope that the THC-O you buy will not harm you.
Meanwhile, you may want to request a CoA for any cannabis product to know the
safety profile of what you are buying.


BENEFITS OF HEMP-DERIVED THC-O

Because of the limited studies on THC-O, the benefits of the cannabinoid remains
unknown. Still, you may attribute to the health benefits of THC, and other
analogs in the case of THC-O. For instance, Uberall (2020) reported that THC
might help with pain, and other THC variants may have the same properties, THC-O
being no exception. Besides, Childs et al. (2017) reported that THC might
relieve discomfort and restlessness and THC-O might have similar anxiolytic
properties. Still, we don’t recommend THC-O for treating or curing any health
conditions until sufficient studies with enough scientific evidence prove this.


IS THC-O LEGAL?

The legal status of many cannabis products is complex, and THC-O is no
exception. When the Farm Bill was passed in 2018, hemp and its extracts with
less than 0.3% THC were declared federally legal. Yet, most hemp-derived
extracts, including THC-O, have their legality in the gray zone. The same law
that declared hemp with less than 0.3% THC allowed states to formulate cannabis
laws that may declare the federally legal products illegal at state levels.
Besides, the same laws state that all synthetic cannabinoids are illegal, even
when derived from hemp. As such, THC-O is technically illegal.


CONCLUSION

Is THC-O stronger than Delta 8? THC-O is a synthetic cannabinoid prepared by
extracting CBD, removing delta-8 from it, and adding acetate anhydride. The
acetate solvent is highly flammable, making it unsafe to prepare THC-O at home.
THC-O is more potent than Delta-8 and Delta-9, so you only need it in small
dosages to feel the same effects. THC-O is psychoactive and may be highly
psychedelic in high amounts like other THC variants. Its health benefits are yet
to be revealed since its studies are limited.


REFERENCES

Childs, E., Lutz, J. A., & de Wit, H. (2017). Dose-related effects of
delta-9-THC
        on emotional responses to acute psychosocial stress.
        Drug and alcohol dependence, 177, 136-144.

Massi, P., Vaccani, A., Bianchessi, S., Costa, B., Macchi, P., & Parolaro, D.
(2006).
        The non-psychoactive cannabidiol triggers caspase
        activation and oxidative stress in human glioma cells.
        Cellular and Molecular Life Sciences CMLS, 63(17), 2057-2066.

Überall, M. A. (2020). A review of scientific evidence for THC: CBD oromucosal
        spray (nabiximols) in the management of chronic pain.
        Journal of Pain Research, 13, 399.

Schlienz, N. J., Lee, D. C., Stitzer, M. L., & Vandrey, R. (2018).
        The effect of high-dose dronabinol (oral THC)
        maintenance on cannabis self-administration.
        Drug and alcohol dependence, 187, 254-260.




MORE BLOGPOSTS


HHC VS. DELTA-9 AND DELTA-8 THC: UNDERSTANDING THE DIFFERENCES

The cannabis industry is interesting and complicated currently, with products
like HHC, Delta-8 THC, and Delta-9 THC. Understanding the compositions,
differences, and similarities is essential for searching this market. An
interesting journey to understand the small differences between HHC, Delta-8
THC, and Delta-9 THC is taken by this blog article. We want to highlight various
aspects of these cannabis products by examining factors like potency, legal
status, chemical structures, side effects, and consequences of drug testing.




TOO STONED? HERE'S HOW TO SOBER UP SAFELY & EFFECTIVELY

In the world of cannabis, a few puffs or a single bite can lead you on a journey
to a heightened state of consciousness. But what if that journey takes an
unexpected turn, and you feel too high? Whether it’s your first time or you’re a
seasoned user, we’ve all been there. This ultimate guide explores effective
strategies to help you sober up from a cannabis high and regain control of your
experience.




CDT CARTS: A COMPREHENSIVE GUIDE

Vaping has become a popular-method of consuming cannabis, offering convenience,
discreetness, and a customizable experience. As the demand for vape products
continues to grow, so does the variety of options available in the market. One
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EXPLORING THE WORLD OF LIVE RESIN: A COMPREHENSIVE GUIDE

Curious about live resin? This revolutionary cannabis concentrate is derived
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Terpenes and aromatic oils secreted by the cannabis plant, are responsible for
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healing properties of cannabinoids by enhancing their effects on the body’s
endocannabinoid system.




THE ULTIMATE GUIDE TO HAZE LIVE RESIN THC DISPOSABLES: A NEW VAPING EXPERIENCE

So, you've decided to dip your toes into the world of THC vaping, huh? Well, my
friend, you're in for a treat! With the introduction of Haze THC Disposable
Devices, getting your fix has never been easier. But before you take that
glorious puff, let me guide you through the wild, hazy adventure that awaits.




FINDING DELTA 8 NEAR ME: EXPLORING THE WORLD OF DELTA 8 THC PRODUCTS

Are you on the hunt for Delta 8 THC products near your location? Delta 8 THC has
gained significant attention lately due to its unique properties and potential
benefits. As the demand for Delta 8 THC continues to rise, many people are
curious about where to find these products conveniently. This comprehensive
guide explores various ways to discover Delta 8 near you, including Delta 8
gummies, delta 8 vapes, and other Delta 8 products. Let’s delve into the world
of Delta 8 THC and explore the best options available!





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Products on this site contain a value of 0.3% or less Δ9THC (or no more than
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