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T-THERAPEUTICS  I  HOME


UNLEASHING THE POWER OF NATURAL T CELLS TO RESHAPE THE CLINICAL LANDSCAPE FOR
CANCER PATIENTS



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HUGE ADVANCES HAVE BEEN MADE IN THE TREATMENT OF CANCER WITH MAJOR BREAKTHROUGHS
COMING FROM THE DEVELOPMENT OF IMMUNO-ONCOLOGY DRUGS SUCH AS CHECK POINT
INHIBITORS AND T CELL ENGAGERS.




THESE DRUGS WORK BY ENABLING THE BODY’S OWN T CELLS TO RECOGNISE AND KILL CANCER
CELLS.


In some cases these drugs are curative. But current approaches are limited, only
working in some cancers and lacking specificity which can cause significant side
effects.



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WE HARNESS THE NATURAL POWER OF T CELLS TO ATTACK AND DESTROY TUMOURS



SCIENCE

T-Therapeutics is driven by a profound purpose: we harness the natural power of
T cells to attack and destroy tumours.

We achieve this by discovering and developing T cell receptor-based drugs
designed to recognise specific cancers and also recruit the patient’s own T
cells to kill the cancer cells and ultimately eradicate the tumour.


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THROUGH OUR PROPRIETARY OPTIMUS® PLATFORM, WE IDENTIFY ‘OPTIMAL’ T CELL
RECEPTORS (TCRS) AS BUILDING BLOCKS FOR PIONEERING CANCER THERAPIES.



TECHNOLOGY

The OpTiMus® platform is a fully humanised TCR mouse which generates fully human
TCRs that don’t exist in the human repertoire. The OpTiMus® platform is not only
able to produce an almost unlimited number of human TCRs, but these also have
unique properties which make them ideal to develop a portfolio of
transformational medicines for cancer.


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WE ARE A NEXT-GENERATION TCR COMPANY, SPUN OUT FROM THE UNIVERSITY OF CAMBRIDGE,
DEEPLY ROOTED IN WORLD-LEADING ACADEMIC SCIENCE.



ABOUT

We combine world-leading expertise in mouse genome engineering, deep expertise
in biopharmaceutical drug development, single cell genomics, machine-learning
and structural biology.

Our inclusive culture is one of creativity, innovation, integrity, community,
diversity and collaboration.


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T-THERAPEUTICS

ABINGTON HALL
GRANTA PARK
CAMBRIDGE
CB21 6AL

Open Source Labware


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