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 * Home
 * Discovery & Development Services
   * Services Available Directly From DTP
   * Services Available Through NExT
   * Stepping Stones
 * Repositories
   * Division of Cancer Treatment and Diagnosis (DCTD) Tumor Repository
   * Repository of Patient-Derived Models
   * Repository of Chemical Agents — Small Molecules and Pure Natural Products
   * Repository of Natural Products
   * Repository of Biologicals — Monoclonal Antibodies, Cytokines and Cytokine
     Standards
 * Databases & Tools
   * DTP Bulk Data for Download
   * DTP Data Search Tools
   * COMPARE Analysis
   * NCI-ALMANAC
   * ROADMAPS Dataset
 * Grants
 * Our Organization
   * Office of the Associate Director
   * Preclinical Therapeutics Grants Branch
   * Molecular Pharmacology Branch
   * Biological Testing Branch
   * Toxicology and Pharmacology Branch
   * Drug Synthesis and Chemistry Branch
   * Natural Products Branch
   * Biological Resources Branch
   * Pharmaceutical Resources Branch
   * Information Technology Branch
   * ImmunoOncology Branch
 * Consultation
 * Contact Us


DEVELOPMENTAL THERAPEUTICS PROGRAM

The NCI Development Therapeutics Program (DTP) provides services and resources
to the academic and private-sector research communities worldwide to facilitate
the discovery and development of new cancer therapeutic agents.


ARE YOU A RESEARCHER IN CANCER DRUG DISCOVERY OR DEVELOPMENT?




DTP BRANCHES AND OFFICES

OAD
Office of the Associate Director
PTGB
Preclinical Therapeutics Grants Branch
MPB
Molecular Pharmacology Branch
BTB
Biological Testing Branch
TPB
Toxicology and Pharmacology Branch
DSCB
Drug Synthesis and Chemistry Branch
NPB
Natural Products Branch
BRB
Biological Resources Branch
PRB
Pharmaceutical Resources Branch
ITB
Information Technology Branch
IOB
ImmunoOncology Branch


DTP SERVICES AND RESOURCES:


DTP DRUG DISCOVERY AND PRE-CLINIC DEVELOPMENT SERVICES

Discovery services (NCI60 screening etc.) and pre-clinical support
(pharmacology, toxicology and cGMP production etc.).


DTP REPOSITORIES

Synthetic compounds, natural products, biological samples and standards.


DTP DATABASES AND SEARCHING/ANALYSIS TOOLS

Bulk DTP chemical and biological data for searching and download, COMPARE
analysis.


DTP GRANT PROGRAMS

Grants for preclinical anti-cancer drug discovery and treatment, including small
molecules, natural products and biological agents.


DCTD CONSULTATIONS

Advice on development of small molecules, biologics, and imaging products
intended for cancer patients.


STEPPING STONES

Access to discrete drug development studies for NCI/DCTD grantees.


ABOUT THE ASSOCIATE DIRECTOR

Rosemarie Aurigemma, Ph.D., has been a programmatic leader in drug development
for over 20 years. Her tenure as the Deputy Associate Director of DTP resulted
in the launch of the Stepping Stones preclinical development program as well as
the initiation and expansion of biopharmaceutical manufacturing support for
adoptive cell therapies. She served as Acting Associate Director of the DCTD
Developmental Therapeutics Program beginning in January 2021 until her permanent
appointment in September 2021. As Associate Director, she will be managing the
oversight and coordination of the programmatic, financial, and administrative
functions for DTP's ten active branches. More…


DTP HOT LINKS

NCI Drug Development Workshop: How to Advance a Therapeutic Candidate from Bench
to Bedside
2023 AACR DTP Presentation
Compound Submission Application for NCI60 Screening
Request Vialed or Plated Compounds
Compound Request Form
Authorize/View Compound Orders
COMPARE Analysis
NCI-60 Analysis Tools (CellMiner)


HIGHLIGHTS

DTP History
Cancer Drugs Developed With DTP Involvement
NExT


WHAT’S NEW

ROADMAPS Dataset
NCI ALMANAC Study Results
Plate of FDA-Approved Oncology Drugs
Sarcoma Project
Small Cell Lung Cancer Screening Project
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