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* About Us
* Overview
We advance the field of genomic science by leveraging our key strengths.
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Dive into the profiles of our faculty members and learn about their
research.
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The NYGC currently has 95 Affiliate Members, representing 18 academic
institutions and medical centers.
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The Project Management team works across disciplines and institutions with
partners in academia, industry, private foundations, and large consortia to
bring the promise of genomics to bear on biomedical research.
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Our dedicated technology transfer personnel identify research results with
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FOSTERING COLLABORATION TO ACCELERATE DISCOVERIES
A premier center for genomic research, the New York Genome Center (NYGC) fosters
collaboration among leading scientists from multiple institutions to accelerate
genomic discoveries and their translation into new therapies and diagnostics.
LATEST NEWS & PUBLICATIONS
* Cell · May 9, 2024
THE FUTURE OF RAPID AND AUTOMATED SINGLE-CELL DATA ANALYSIS USING REFERENCE
MAPPING.
Satija Lab
* Cell Genomics · May 1, 2024
THE BROKEN ALZHEIMER’S DISEASE GENOME.
Phatnani Lab Neurodegenerative Disease
* medRxiv · April 25, 2024 · Preprint
MITOCHONDRIAL GENOME VARIANTS ASSOCIATED WITH AMYOTROPHIC LATERAL SCLEROSIS
AND THEIR HAPLOGROUP DISTRIBUTION.
Phatnani Lab ALS Consortium
May 8, 2024
GOT-CHA: A NEW TOOL FOR DETAILING HOW GENE MUTATIONS AFFECT CELLS
Landau Lab
All Publications
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SHARED STORIES OF SUCCESS
SHARED STORIES OF SUCCESS
The NYGC has built a unique scientific ecosystem for multi-institutional
collaborations in genomic research. Leveraging our strengths and expertise in
collaboration, sequencing at scale, genomic analysis, and technology
development, we advance novel approaches and partnerships beyond that possible
for any single institution to gain insights into the biological drivers and
molecular mechanisms of disease, with the goal of advancing the practice of
precision medicine.”
Tom Maniatis, PhD Evnin Family Scientific Director & CEO Isidore S. Edelman
Professor of Biochemistry and Molecular Biophysics, Columbia University
SHARED STORIES OF SUCCESS
With this [BD2] collaboration, we will apply cutting-edge sequencing technology
to gain insights into the genetic architecture and biology underlying a
neuropsychiatric disorder that has been under-studied and poorly understood thus
far.”
Click here to read more about the BD2 grant.
Thomas Lehner, PhD, MPH Scientific Director, Neuropsychiatric Disease Genomics,
NYGC
SHARED STORIES OF SUCCESS
Mutations that alter the RNA-splicing process underlie many cancers and other
disorders. This work allows us to track the impacts of those changes at an
unprecedented level of detail.”
Read more on this study.
Dan A. Landau, MD, PhD Core Faculty Member, NYGC Associate Professor of Medicine
in the Division of Hematology and Medical Oncology and the Department of
Physiology and Biophysics, Weill Cornell Medicine
SHARED STORIES OF SUCCESS
Decoding causality is fundamental to providing interpretable quantitative
explanations of elements of the non-coding genome in cancer. Biological problems
of this nature require cross-cutting programs where investigators with a broad
range of expertise are supported to collaborate and focus on building new
measurement methods and computational frameworks to understand the complex
dynamics of cancer biology.”
Read more on the MacMillan Center for the Study of the Non-Coding Cancer Genome.
Samuel Aparicio, BM, BCh, PhD, FRCPath, FRSC Senior Scientific Director of
Cancer Genomics, NYGC Chair of Molecular Oncology, UBC/BC Cancer Agency
Senior LeadershipNeuropsychiatric DiseaseLandau LabCancer Research
Collaborative Research Programs
GROUNDBREAKING RESEARCH
We cultivate a diverse research community dedicated to advancing the
understanding of genomic science and the treatment of human disease.
* Cancer Research
* Neurodegenerative Disease Research
* Neuropsychiatric Disease Research
* Biology, Genomics & Technology
* Scientific Collaboration & Project Management
NYGC AT A GLANCE
* 13 Founding and Associate Institutional Members
* 4 NIH Innovator Awards
* 10 Core Faculty
* 10 Associate Faculty
* 148K+ Whole Genome Equivalents Sequenced
* 95 Affiliated Scientists Across 18 Institutions
* $143M Grants Under Management*
*as of 12/2023
Technology Platforms
INNOVATIVE TECHNOLOGY PLATFORMS
Our multidisciplinary team of scientists, engineers, and NYGC faculty come
together to explore and test innovative genomic tools and technologies to drive
progress within our center and the broader scientific community.
* Technology Innovation
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CELEBRATING DIVERSE PERSPECTIVES
At the NYGC, we’re committed to building a diverse, equitable, and inclusive
workplace culture where everyone can contribute to our mission of advancing
genomic research.
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