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REVVITY SIGNALS™- WHAT'S NEW The Signals Research Suite is a complete, integrated data capture, processing & analysis SaaS software for scientific research. Capture, manage, and share experiment data, notes and research findings in a secure and accessible environment built on the foundation of Signals Research Platform. Check out the latest improvements. 23.5 June 2023 (Update to E3 in November 2023) - What’s New This version 23.5 release of Signals brings improvements to Signals Research Suite through Signals VitroVivo and Inventa, Inventory and Materials. We have continued to work on our ongoing beta capabilities for Worksheets and Internal Data Sources and added a new beta capability around HELM monomers. Finally, we have also fixed a number of small bugs. The following improvements are available for users of Signals Notebook Individual Edition, Signals Notebook Standard, Signals Notebook Private Cloud, Signals Research Suite Standard and Signals Research Suite Private Cloud. Certain features may only be available with appropriate licensing and/or with enablement by an administrator. * Fundamentals * * – Tooltip to display names for long content in the side pane * VitroVivo * * – Revised and improved data model for in vivo applications * – New Sequence File Generator App for creating sample run lists for LC/MS assays * Inventa * * – External Data Sources * – SAR Layout Permissions * – Append structures to measurement tables * – Clone measurement types * Chemistry * * – Copy structure(s) as formats other than CDX, CDXML * – HELM Monomer editor (beta) * Worksheets * * – Improved administration view for editing and previewing Worksheet templates * – Integer fields will show a warning if number not in specified range * – Integer fields will not allow entry if number not in specified range * – Date/Time fields will show a warning if number matching a certain time relative to the time of entry * – Date/Time fields will not allow entry if number matching a certain time relative to the time of entry * Inventory * * – Variable Measure Property * – Attachments for Containers and Locations * Materials * * – Hide empty fields * – Option to expand the canvas of chemical materials * Administration * * – Select next level content in Configuration Transfer of Admin Defined Objects * – Updates to Inventory Admin Role, Inventory Admin System Group * Integrations & APIs * * – Multiple API Keys per tenant * – Internal Data Sources (beta) * – Limiting moles/solvent ratio * – Enter, update or clear a value for a Timestamp field in Worksheets * – Reopen Experiments, ADOs, Parallel Experiments * – API endpoint to Refresh External Lists We also fixed several small bugs in this release. Details of the enhancements are described below. Administrators should note that we have changed the way that the Inventory Administrators have access to Inventory functionality in System Configuration. We have added an Inventory Admin System Group, to which all users with the Inventory Admin Role are automatically assigned. The Inventory Admin role will now also be permanently assigned relevant privileges for the management of Inventory including all Container and Location related privileges. If Administrators would prefer that current users with the Inventory Admin role do not have all of these privileges, they should create a new Role for these users and assign the desired privileges. Administrators should note that we will be updating the Concentration field in the Materials Library and Variable Measures using the measure called “Count” to be a COUNT measure instead of an INTEGER. The entered values will not be affected. Any use of the external APIs using this field may need to be updated appropriately. Administrators are recommended to subscribe to the channels within our support news site found at https://informatics-support.perkinelmer.com/hc/en-us/categories/360004446171-Support-News which contains more information about releases and other pertinent product information. This content is anticipated for release on our Production E3 environments, and for Private Cloud customers on our deferred release schedule, in November 2023. Further Details The following improvements are available for users of Signals Notebook Individual Edition, Signals Notebook Standard, Signals Notebook Private Cloud, Signals Research Suite Standard and Signals Research Suite Private Cloud. Certain features may only be available with appropriate licensing and/or with enablement by an administrator. Fundamentals Full content names exceeding the width of the side contents pane can now be reviewed with a simple hover over tooltip. VitroVivo The data model for in vivo applications has been revised and improved to support design and execution of advanced animal studies involving multiple treatment cohorts. This new data model will now support creation of study cohorts (e.g., Male or Female cohorts, Wild Type or Transgenic cohorts) and associated treatment groups. Users can now have access to the new Sequence File Generator App in the In Vivo Apps section. This App will help users to create a run list of samples for LC/MS Instruments from existing plate designs. Inventa Administrators can now connect External Data Sources, allowing them to leverage SQL queries to directly import data for mapping and indexing. Users can now specify the privileges on shared SAR Layouts: Read, Write, or Full Control. Those with Read privileges and view and use a SAR Layout, but cannot modify its settings. Write privileges grant the ability to edit, and Full Controls adds the ability to share and delete a layout. Users now have the option to append structures to measurement tables retrieved via Global Search. A column of structures can be applied to both Parent and Detail level measurement types, and the settings saved with the query. Administrators can now clone measurement types. Cloned measurement types will inherit all the attributes and secondary mappings as the original measurement type. Chemistry Users have additional formats available for the Copy as function for chemically defined items. Selected structures may now be copied as HELM, HELM (Natural Monomers), SMILES, MOL V3000, MOL V2000, InChI, InChI Key, or SLN. Inventory The Variable Measure Property is a new field type that is available to Administrators in Inventory and Materials (batch/lots as well as compound/assets). It allows Administrators to choose which unit families the users are able to select from: The list shows the family units as well as the conversions to the end users when entering values into properties using these property types: Containers and Locations have a new field type of Attached file that can be used to upload documents. Admins can create the properties in the Inventory Containers or Locations Properties: Administrators will need to add the property to the Container or Location type: Existing Container/Locations will have the new field available upon edit. Users will see a note at the top of the screen identifying the new property: When users create new Containers/Locations, the property is available to have a document uploaded: Materials In the Material Properties tab of a Container in Inventory, there is a filter option in the right top corner. This will hide any empty rows in the Material Properties tab when toggled on: After: In the Materials Library, in the Compound/Asset page there is the same filter option to hide empty rows: After: Users can now also enlarge the canvas for any chemical Material. The properties will still be on the page after expansion in both view and edit modes. Administration Configuration transfer of Admin Defined Objects now allows selection of the individual settings for Activation, Auto Numbering, Templates and others. By default the Auto Numbering setting is deselected and all other settings are selected. The Inventory Admin role has been enhanced to facilitate access to the capabilities required. Users who are assigned the Inventory Admin role are automatically added to the new System Group called Inventory Administrators. They will also have some relevant privileges such as configure System, Inventory App and Manage System Templates automatically assigned. Only System Admins or Inventory Admins can activate or deactivate Inventory. Integrations & APIs Admins can now generate Multiple API Keys per tenant to allow different API users to perform specific integrations. The maximum currently allowed per tenant is 10 API keys. We have extended the GET/stoichiometry/{eid} endpoint to return the Limiting Moles/Solvent Ratio from ChemDraw Documents. The PATCH/worksheet/{eid} endpoint has been enhanced to allow patch of a Timestamp property into a Worksheet. The request allows the developer to request that the value be “now” upon which it takes the current server time, or “clear” whereby the field value is removed. We have added a new endpoint to allow a developer to reopen an Experiment, parallel Experiment or Admin Defined Object. The new endpoint POST/entities/{eid}/reviews/reopen will allow an experiment or similar object to be Reopened from Closed, Voided or In Review states. We have added and enhanced endpoints to allow programmatic refresh of an External List. The endpoint POST/attributes/{eid}/refresh is an asynchronous endpoint which will queue the refresh of an External List. The status of the refresh is available via the endpoint GET/attributes/{eid}. The following capabilities are in beta and are only available to users and administrators of Signals Notebook Standard, Signals Notebook Private Cloud, Signals Research Suite Standard and Signals Research Suite Private Cloud upon request. Please contact your account representative or our support team if you would like access to the following features. They are unavailable as part of Signals Notebook Individual Edition. Chemistry Signals Notebook now includes native support for Hierarchical Editing Language for Macromolecules (HELM). This open format lets users represent complex and larger biopolymer modalities in a simpler format while maintaining all atom representation. To utilize the new feature, a Signals Notebook System Admin must activate any of three out-of-the-box HELM Monomer libraries. The configuration of these libraries is in a new section of Signals Configuration. The libraries included in this release are the Natural Monomers, the Pistoia Alliance Monomers, and the Signals Monomers. System admins may choose to activate any of these libraries and change the sort order of the libraries. In this release, custom monomer libraries cannot be created, and no monomers may be added to any of the system HELM Monomer libraries. New permissions are available, though only the management of Libraries is relevant for this release. Access to the Monomer Libraries is dependent on Security Policy and Group Association Settings. Once at least one HELM Monomer Library is activated, users with access will be able to access the HELM editor in any ChemDraw Canvas. This tool will enable users to add biopolymer building blocks one by one as well as enter a text string in several formats to quickly add a HELM structure to the canvas. Users may also quickly replace a monomer in an existing biopolymer. Users can toggle through different libraries and different monomer types to make their preferred selection. In this release, the Favorites tab will only store selections within the user’s local browser storage. Worksheets We have improved the editing experience for Worksheet Templates. The button to add new fields is now more prominent and the administrator can now easily navigate between the Editor mode and Preview modes by accessing the two tabs. This allows the admin to define new fields, stay in the “Try It Out” mode to better iterate on their design. Integer and date/time fields can now be set to enforce conditional entry. Integer fields can be set to only allow values above or below a given value, or values within or outside of a given range. The fields can also be set to allow values out of range but display the fields with a warning. Date/time fields can also be set with a condition, to prevent values, or to allow values out of range while providing a warning. Date/time value conditions are set relative to the time/date of data entry by the end user. Integrations & APIs Fields from internal entities can now be mapped into an Internal Data Source for use in ADTs similar to how fields for external sources can be mapped. This functionality has been expanded from just Materials and Samples to include: Experiments, ADOs, Tasks, Requests, Parallel Experiments, Notebooks, and Inventory Containers, and Locations. A new “Internal Data Source” can now be created with admin defined fields. The admin can select from a list of available data types. The list of properties available for mapping is automatically filtered based on the selected data type. Once the Data Source is defined, it can be used in ADT templates (including templates with formulations) similarly to how External Data Sources can currently be utilized. When creating a table template the “External Data Source” option will now be a “Data Source” option and include Internal Data Sources. Key field identified with Key icon and automatically added to the template. Additional mapped columns can be manually added. This differs from existing External Data Source behavior as currently all mapped External Data Source Columns are added automatically. The IDS requires that you manually add the columns as not all of them will consistently be needed. Mapping behavior is consistent with existing External Data Source functionality. For the end user, the behavior of the Internal Data Source reference is very similar to the existing External Data Source behavior. Selecting the field brings up a pre-filtered search modal similar to what is available in QuickAdd. Mapped columns automatically populate in a manner consistent with what is available for External Data Sources 23.4 May 2023 (Update to E3 in November 2023) + What’s New This version 23.4 release of Signals brings improvements to Signals VitroVivo, Signals Inventa, integrated admin defined tables, Inventory, and some new administrative controls. We have released formerly beta capabilities around Material Tables, Sample Statuses and Inventory Decrements to all systems and these capabilities no longer need to be requested to be available. We have continued to work on our ongoing beta on Worksheets and added a new beta capabilities around Internal Data Sources and BLAST searching. Finally, we have also fixed a number of small bugs. The following improvements are available for users of Signals Notebook Individual Edition, Signals Notebook Standard, Signals Notebook Private Cloud, Signals Research Suite Standard and Signals Research Suite Private Cloud. Certain features may only be available with appropriate licensing and/or with enablement by an administrator. * Fundamentals * * – Updated Help Center * VitroVivo Apps * * – New transformations captured in the Calculations Explorer (filtered rows and excluded columns) * – SPR Data import now supports files larger than 500MB and multiple files * Inventa * * – Additional locking parameters for Publish Measurement App workflows * – Share options for SAR Layouts * Admin Defined Tables * * – Improved handling of timeouts when calling multiple rows in a connected External Data Source * Materials Tables * * – Bulk registration (available to all systems) * – Bulk edit (available to all systems) * Samples * * – Statuses for Samples (available to all systems) * Worksheets (beta) * * – Timestamp Field type allows end user to enter “Now” * – Fields can be required to have a value before signing * – Number and Number with Unit fields will show a warning if number not in specified range * – Number and Number with Unit fields will not allow entry if number not in specified range * Inventory * * – Decrement Inventory containers from stoichiometry table (available to all systems) * – Revert experiments using Inventory Decrements in stoichiometry tables (available to all systems) * – Warn users when deleting an element or an experiment with linked containers and deprecated amounts (available to all systems) * – Additions to Total Amount in containers * – Switch containers in stoichiometry table (available to all systems) * – Updates to Switch containers in stoichiometry table * Materials * * – Freeze column headers on Batch page * Search * * – Biological Sequence search (beta) * Administration * * – Product license assignment at user level * – Enable users to more readily find other users with differing email domains * – Limit end user sharing to only allow increasing access to user who already have View * – Change default to not transfer Starting Number for object Autonumbering when transferring configuration * – Prevent users from creating, editing or deleting comments * Integrations & APIs * * – Internal Data Sources (beta) * – External Notifications on Export to ZIP/PDF * – PATCH Plates * – Bulk change Status of Samples We also fixed several small bugs in this release. Details of the enhancements are described below. The following OnDemand videos for Signals Notebook Administrators are now available * Create mandatory content within templates Rel.May 2023 * Inventory - Customizing Container Label Templates Rel.May 2023 Administrators should note that we will be updating the Concentration field in the Materials Library and Variable Measures using the measure called “Count” to be a COUNT measure instead of an INTEGER. The entered values will not be affected. Any use of the external APIs using this field may need to be updated appropriately. Administrators should note that we are changing the way that the Inventory Administrators have access to Inventory functionality in System Configuration. We will be adding an Inventory Admin System Group, to which all users with the Inventory Admin Role will be automatically assigned. The Inventory Admin role will also be permanently assigned relevant privileges for the management of Inventory including all Container and Location related privileges. If Administrators would prefer that current users with the Inventory Admin role do not have all of these privileges, they should create a new Role for these users and assign the desired privileges. This change will be available in a future release. Administrators and end users should note that we have updated the URLs used to access Signals. If you use a bookmark that does not have the “/elements” suffix, such as http://your_name.signalsnotebook.perkinelmer.cloud or https://your_name.signalsnotebook.perkinelmercloud.eu, then this URL will now go to a homepage that allows access to multiple Signals products. To go directly to your Signals Notebook please update your bookmark to append “/elements” onto the end of your URL, such as https://your_name.signalsnotebook.perkinelmercloud.eu/elements. Administrators and users should note that we will now purge old notifications, both end user notifications available under the bell icon, and External Notifications enabled via the administration console SNConfig. Notifications will now only be stored for 6 months. This change is implemented in this release. Administrators are recommended to subscribe to the channels within our support news site found at https://informatics-support.perkinelmer.com/hc/en-us/categories/360004446171-Support-News which contains more information about releases and other pertinent product information. This content is anticipated for release on our Production E3 environments, and for Private Cloud customers on our deferred release schedule, in November 2023. Further Details The following improvements are available for users of Signals Notebook Individual Edition, Signals Notebook Standard, Signals Notebook Private Cloud, Signals Research Suite Standard and Signals Research Suite Private Cloud. Certain features may only be available with appropriate licensing and/or with enablement by an administrator. Fundamentals All users now have access to the redesigned Help Center. The content has been expanded to support Signals Research Suite. VitroVivo Apps Two additional Spotfire transformations are now captured in the Calculations Explorer templates: Filtered Rows and Excluded Columns. To include transformations the user must enable the ‘Include transformations’ toggle accessible when selecting the table in the Create Template area. SPR Data Import now supports files multiple files for Biacore (.blr files and Insight exported .json files) and Carterra instruments. Data files larger than 500MB are also now supported for all instrument types. Inventa Users can now lock the additional parameters in the Publish Measurements app when added to a Workflow. Notably, the individual mapping assignments and publish data method can be locked providing Workflow creators with more control over the publication process. Users can choose to share a SAR table layout with one or more Groups or keep the layout private. Private layouts cannot be viewed or modified by other users. Admin Defined Tables We have updated the method that we use to load rows into an admin defined table, when the rows are sourced from an external database via a lookup ID. The lookups are now sent in batches, which alleviates timeout issues with larger sets of ID lookups. Materials Tables Materials tables enabled for registration will now be capable of bulk registration, bulk editing, and CSV upload. These capabilities, previously available under our beta released capabilities, are now available to all systems. Samples Sample Statuses, the ability to transition samples from one status to another, and associated privileges, in now available to all systems. Inventory The use of decrements from linked containers in the stoichiometry table is now available to all systems. This includes all associated capabilities including the ability to decrement Inventory containers from the stoichiometry table, to prevent reversion of experiments with decremented amounts in stoichiometry tables and to warn users when deleting an element or an experiment with linked containers and deprecated amounts. The Batch and Containers pages now show a total number of containers available followed by the number of disposed containers, reported under the Total Container Amount: A hover over window appears for a given compound that contains the Total Container Amount: The ability to switch containers is now available to all systems. If no value is typed into the Inventory Decrement column, users will not get a warning. When users switch containers the name of the Material from the stoichiometry table will be at the top of the window. If the name of the Material name is blank, users will see the Material ID instead. The column header will freeze to allow users to scroll longer lists of containers: Materials When users scroll vertically on the batch page, the headers will now remain visible: Administration The users page now supports product license assignment at the user level. License assignments can be set on the main user page, on the create and edit user pages, as well as with the bulk update. This revised Users page is only available on tenants with appropriate licensing. We have added a new privilege “Broad User Search” to enable users to more readily find other users with differing email domains by first and last name instead of requiring the full email address. This functionality will be available for user searching throughout Signals for example in Sharing and addition of reviewers. Administrators can now also allow a more limited sharing option for end users via a “Read Dependent Share” privilege. Users with this “Read Dependent Share” privilege will be only be able to share content with other users who already have View access via the security policy. If a user has been granted access via sharing and then loses View access to the entity via security policy, the sharing user only has the option to remove access via sharing and cannot grant further access or alter the level of access via sharing. The Configuration transfer of Experiments, Notebooks, Parallel Experiments, Requests and Admin Defined Objects will now not transfer the Starting Number for the object Autonumbering by default. For Experiments, Notebooks, Requests, and Parallel Experiments, the setting can be enabled by the administrator if desired on import. We have also added a new privilege to allow administrators to control if end user can create, edit and delete Comments. If a user does not have the “Add/Edit/Delete Comments” privilege they can still see existing comments but cannot write new comments, or edit or delete existing ones. Integrations & APIs External Notifications can now be triggered on the export of entities to PDFs and/or ZIP files. We have added a series of endpoints to our External APIs for the manipulation of Plates. The GET/plates/{plateContainerID}/plates, GET/plates/{plateContainerID}/plates/{id}, PATCH/plates/{plateContainerID}/plates/{id} and PUT/plates/{plateContainerID}/plates/{id} allow developers to get individual Plates, edit them or replace them. The endpoint PATCH/samplesTables/{samplesTableId}/rows has also been enhanced to allow for the bulk update of the Status of Samples. The following capabilities are in beta and are only available to users and administrators of Signals Notebook Standard, Signals Notebook Private Cloud, Signals Research Suite Standard and Signals Research Suite Private Cloud upon request. Please contact your account representative or our support team if you would like access to the following features. They are unavailable as part of Signals Notebook Individual Edition. Worksheets Administrators can now define a new property of type TimeStamp. When this property is added to a Worksheet the end user can enter the current date/time with a single click. Once entered the value can be removed, or updated with a new current timestamp. Fields can also be defined as to require the end user to enter a value before a singing event can occur. If the end user attempts to sign a Worksheet where the fields are empty, the signing workflow will be prevented and the end user warned that there are fields to complete. Admins can now also define that fields of type Number and Number With Unit only allow numbers within certain ranges to be entered. The admin can define that the value is accepted but shown as a warning if out of range, or that the value cannot be entered. Search Users may search using biological sequences using the the new search field “Biological Sequence”. The user may choose a substring, exact, blastn, or blastp type of search. Match substring type finds an exact match of the user query within a potentially larger sequence. Match exact finds sequences that match the query exactly. Blast type searches will find regions of similarity between the query and biological sequences in the system. Blastn is for DNA searches while blastp is for protein searches. Blast type searches require at least 27 characters and will not allow unexpected characters for searching. Integrations & APIs Fields from internal entities can now be mapped into a Data Source for use in ADTs similar to how fields for external sources can be mapped. This functionality is currently limited to Materials and Samples. A new “Internal Data Source” can now be created with admin defined fields. The admin can select from a list of available data types. The list of properties available for mapping is automatically filtered based on the selected data type. Once the Data Source is defined, it can be used in ADT templates (including templates with formulations) similarly to how External Data Sources can currently be utilized. When creating a table template the “External Data Source” option will now be a “Data Source” option and include Internal Data Sources. Key field identified with Key icon and automatically added to the template. Additional mapped columns can be manually added. This differs from existing External Data Source behavior as currently all mapped External Data Source Columns are added automatically. The IDS requires that you manually add the columns as not all of them will consistently be needed. Mapping behavior is consistent with existing External Data Source functionality. For the end user, the behavior of the Internal Data Source reference is very similar to the existing External Data Source behavior. Selecting the field brings up a pre-filtered search modal similar to what is available in QuickAdd. Mapped columns automatically populate in a manner consistent with what is available for External Data Sources. 23.3 March 2023 (Update to E3 in July 2023) + What’s New In this version 23.3 release we are excited to announce the release of SaaS Signals Research Suite, a new offering with Signals Notebook, VitroVivo, and Inventa combined into a single product. Signals Research Suite provides comprehensive scientific data management and analytics supporting all R&D activities. Learn more. Signals Research Suite is built on the same platform as Signals Notebook, so any Signals Notebook users who are interested in seamlessly upgrading their implementation to the Suite are encouraged to contact their sales representative. Further, this release brings changes to the Help, login home page and an app launcher to navigate between applications. We have brought a series of improvements to our Inventory capability and to the use of inventoried containers for Materials. We have continued to work on our ongoing beta on Worksheets and added a new beta capability around adding Statuses for Samples. Finally, we have also fixed a number of small bugs. The following improvements are available for users of Signals Notebook Individual Edition, Signals Notebook Standard, Signals Notebook Private Cloud, Signals Research Suite Standard and Signals Research Suite Private Cloud. * Usability * * – Release locks on Microsoft Office desktop files * – Email Notification for Shared Bookmarks/Queries * – Home App * – App Launcher The following improvements are only available for users of Signals Notebook Standard, Signals Notebook Private Cloud, Signals Research Suite Standard and Signals Research Suite Private Cloud. Some capabilities may only be available with appropriate licensing. * Usability * * – Display of External List derived Attributes in tables show additional detail in hover over * Signals Inventa & Signals VitroVivo * * – Updated Help Center * – Signals Inventa dashboard & workflows * – TIBCO Spotfire for Signals install * – Administrative control of settings & user roles * Inventory * * – Revert experiments using Inventory Decrements in stoichiometry tables (beta) * – Switch containers in stoichiometry table (beta) * – Total Amount in containers displayed in Materials, Display Total Amount of containers in Assets without Batches in Materials Library (available to all users) * – Searching for Total Amounts in containers * Materials * * – Show/Hide Disposed filter on all Containers pages * – Disposed containers show with strikethrough on Containers page * Materials Table * * – Registration from Materials Tables (available to all administrators) * – Create child materials from the Materials Table (available to all administrators) * – Creation of lots/batches with the Material Table (available to all administrators) * Samples * * – Statuses for Samples (beta) * Administration * * – Filtering for Worksheet locking events in Admin Audit trail * – Configuration transfer of Field Locking reasons * Integrations & APIs * * – GET Field Locking reasons for use in editing locked Worksheet fields * – PATCH Worksheets with locked fields * – POST/PATCH containers includes home location * – Update Sample Status * – GET/POST/PATCH multi-value attributes lists sourced from External lists * Worksheets (beta) * * – Indication that a locked field has been previously edited * – Return to Locked field to continue editing * – Print Worksheets We also fixed several small bugs in this release. Details of the enhancements are described below. The following OnDemand videos for Signals Notebook End Users are now available * Advanced Search in Signals Notebook * ELN Archive Deeper Dive Administrators should note that the capability to define reasons for changing locked fields used in Worksheets, which was described in the previous (23.2) update, was erroneously described as being in beta and only available on request. This capability is actually available to all administrators albeit has no utility without enablement of the Worksheets capability. Administrators and users should also note that due to a change in our Chemical Drawing capability, Chemical Drawings will not load in versions of Safari older than 16.3. We strongly recommend that all users always use the most up to date version of their browser. Administrators should note that we are changing the way that the Inventory Administrators have access to Inventory functionality in System Configuration. We will be adding an Inventory Admin System Group, to which all users with the Inventory Admin Role will be automatically assigned. The Inventory Admin role will also be permanently assigned relevant privileges for the management of Inventory including all Container and Location related privileges. If Administrators would prefer that current users with the Inventory Admin role do not have all of these privileges, they should create a new Role for these users and assign the desired privileges. This change will be available in a future release. Administrators and end users should note that we will be updating the URLs used to access Signals Notebook in a future release. If you use a bookmark that does not have the “/elements” suffix, such as http://your_name.signalsnotebook.perkinelmer.cloud or https://your_name.signalsnotebook.perkinelmercloud.eu, then this URL will soon go to a homepage that allows access to multiple Signals products. To go directly to your Signals Notebook please update your bookmark to append “/elements” onto the end of your URL, such as https://your_name.signalsnotebook.perkinelmercloud.eu/elements. Administrators and users should note that we will soon be purging old notifications, both end user notifications available under the bell icon, and External Notifications enabled via the administration console SNConfig. Notifications will now only be stored for 6 months. This change will be implemented in a future release. Administrators are recommended to subscribe to the channels within our support news site found at https://informatics-support.perkinelmer.com/hc/en-us/categories/360004446171-Support-News which contains more information about releases and other pertinent product information. This content is anticipated for release on our Production E3 environments, and for Private Cloud customers on our deferred release schedule, in July 2023. Further Details Usability Users can now override any locks that exist on the editing of Microsoft Office documents when opening to edit in Microsoft Office Desktop. The user is informed if a lock exists and who owns the lock. Overriding the lock will take control of editing the document, if the user with the previous lock is still working their changes will no longer be recorded. The lock override is recorded in the History as a discrete event. Users are now able to receive an email notification when a search query is shared with them by turning on the email notification option for “When someone shares an item with me” in their notification settings. The user will receive an email notification with a link to the search. A New Home App allows easy access to subscriptions, tools, and other items to explore. The Home App will show applications available to you. Users can also navigate between Apps, and to the Home App by using the App Launcher accessible to the right of their username. The following improvements are only available to users and administrators of Signals Notebook Standard, Signals Notebook Private Cloud, Signals Research Suite Standard and Signals Research Suite Private Cloud. Some capabilities may only be available with appropriate licensing. Usability Users will now be able to see additional detail for values from External List derived Attributes in tables with a hover over. This will apply to single-select and multiselect fields and will be available for ADTs, Materials, Samples, Tasks, Stoich tables, Worksheets, and Inventory Locations and Containers. Signals Inventa and Signals VitroVivo The Help Center has been redesigned with expanded content to support Signals Research Suite. Users now have a dedicated dashboard for their Inventa Projects and Analyses. The dashboard is backed by the new system object, Inventa Analysis. An example Inventa Analysis is provided out-of-the-box. A dedicated smartfolder allows users to easily search through their entire Inventa Analysis collection. Users can create a new Inventa Analysis by launching any of the Inventa applications from the dashboard or from the Add New button. The Inventa Analysis contains an interactive preview of associated compounds that is linked to the SAR Analysis app inside of Signals Inventa. Visualizations can be directly exported from Spotfire for Signals into the Inventa Analysis object. This allows users to capture visualizations at a snapshot in time. Visualizations inside the Inventa Analysis support annotations. Within Spotfire for Signals, users can browse and open existing Inventa Analyses. Users can now install TIBCO Spotfire for Signals from the Home App by clicking the install link under tools and following the instructions. Administrators now have settings to manage Signals Research Suite. Inventa settings are found on the Signals Configuration Home Page and additional settings are found on the PerkinElmer Signals Apps page within TIBCO Spotfire for Signals. Administrators can control which user groups have the privilege for managing VitroVivo and Inventa by setting privileges within Users Roles page in Signals Configuration. Inventory The ability to display Total Amounts of Materials in Containers, at the Material, Asset/Lot and Container levels, is now available to all users. Users can now search for results via the Total Amounts of Materials in containers. The search filters are easily found by typing “ REPORT” into the Add filter option to see the 3 Amount Available search options, to search via Total Mass, Volume or Count. The filter can be further refined by defining ranges or other conditions similar to other numerical filters, or combined with other filters to narrow down results. The Total Amount filter is available from both Materials and Inventory searches. The results returned can include both the Material in addition to the individual Batch/Lots if additional filters are not applied. Materials Disposed Containers can optionally hidden, or shown again, on all Containers pages. Container pages are now displayed on all Material Libraries, both those with and without Batch/Lots. Disposed containers are shown with strikethrough on the Containers page. Disposed containers are also shown with a strike through when the corresponding batch is expanded: Materials Tables The ability to enable registration functions from the Materials Table is now available to all administrators. Enabling this option will expose capabilities for end users to Register Materials, Lots/Batches and Child Materials directly from Materials Tables as previously available under our beta released capabilities. Administration We have added an Action filter for the field locking events in the Admin Audit trail to facilitate administrators identifying changes to locked fields in Worksheets. The Field Locking reasons can now also be transferred between tenants via Export/Import of the Configuration. Integrations & APIs We have added a new endpoint GET/worksheet/settings/unlock/reasons to allow retrieval of the Field Locking reasons. The endpoint PATCH/worksheet/{eid} has also been updated to allow the reason ID to be used when editing a locked field. We have also updated the POST/inventory/containers and PATCH/inventory/containers/{containerId} endpoints to allow definition of the Home Location of containers. The Status of Samples can be updated programmatically via the new endpoint PUT/samples/{sampleId}/status. The recent extension to allow multiple values in Attribute Lists derived from External List sources is now supported via our public APIs. Relevant endpoints, for Tables, Samples etc. now allow the retrieval and updating of such properties with multiple values. The following capabilities are in beta and are only available to users and administrators of Signals Notebook Standard, Signals Notebook Private Cloud, Signals Research Suite Standard and Signals Research Suite Private Cloud upon request. Please contact your account representative or our support team if you would like access to the following features. They are unavailable as part of Signals Notebook Individual Edition. Inventory If a user tries to revert a change to a ChemDraw Document where the reversion would change the Decremented amount of a reagent, the reversion will now be disallowed and the user presented with an error. This is to prevent accidental inaccuracies in Inventory containers. Changes that do not require a change in the Decremented amount are still allowed. Users who have attached container to the stoichiometry table via Quick Add/Search or type ahead now have a new “switch” icon in the Container ID field. When clicked, the switch icon will present the user with a warning. If an amount is present in the Inventory Decrement cell, that amount is deducted from the currently selected container. To avoid this, users should update the Inventory Decrement cell to be 0. Once Confirmed, users will have the option to change the container to a different container of the same material and batch/lot (if applicable). Containers that are deleted, disposed or final disposed will not be in the available list. Once the new Container has been selected, the Reagent will be updated with the associated Barcode and Container ID. Worksheets Locked fields now indicate when they have been changed since entering the initial value. If the originally entered value has been updated, requiring the author to enter a reason for the change, the lock symbol is now displayed in blue to indicate that the field has changed at least once. The Reason For Change dialog has been enhanced to allow the author to return to the field to continue making changes, without locking the field but without having to unlock the field again. Worksheets are also now included when printing an Experiment to PDF. Samples Samples will now have a “Status”. The current Statuses are: Active which has the same behavior as what is currently available for Samples, and two new “Read Only” Statuses Closed and Canceled. Active samples can be Closed or Canceled. Closed or Canceled samples can be reopened if any edits must be made. Once a sample is canceled or closed, it cannot be edited, registered as a material, content cannot be added, and new containers cannot be added. Closed or Canceled samples can still be referenced in Tasks or referenced in the Quick-Add. The Admin can limit which users are able to transition samples from one status to another through 2 new privileges: “Close/Cancel Samples” and “Reopen Samples”. External Action triggers on Samples can now also be limited based on Sample Status. For all existing external actions on Samples, the trigger options default to showing the action in all sample statuses. 23.2 February 2023 (Update to E3 in July 2023) + What’s New This version 23.2 release of Signals Notebook brings additional capabilities for our ongoing beta capabilities for Worksheets, Materials Tables, Inventory Decrements and Amount Rollups. The prior beta capabilities around additional chemically aware libraries is now available to all administrators. We have also added the ability to use Externals Lists as multi-value attributes and for an administrator to manage any active tokens for integrated products using a bearer token exchange. Finally, we have also fixed a number of small bugs. The following improvements are only available for users of Signals Notebook Standard and Signals Notebook Private Cloud * Inventory * * – Warn users when deleting an element or an experiment with linked containers and deprecated amounts (beta) * – Display Total Amount of containers in Assets without Batches in Materials Library (beta) * Materials * * – Additional Chemically Aware Libraries (available to all administrators) * Materials Table * * – Bulk registration (beta) * – Bulk edit (beta) * – Upload from csv file (beta) * Administration * * – View and Expire active Bearer Tokens * – Define multivalue attributes for External Lists * Integrations & APIs * * – Replace ChemDraw Document * – Lookup total inventory amounts of materials * Worksheets (beta) * * – List, multivalue list fields * – Text field supporting multiple lines of entry * – Lockable fields * – Definition of reasons for changing locked fields We also fixed several small bugs in this release. Details of the enhancements are described below. The following OnDemand videos for Signals Notebook Administrators are now available * Building Hierarchical Attributes The following OnDemand videos for Signals Notebook End Users are now available * Using Hierarchical Attributes on System Objects and Admin Defined Tables Administrators should note that we are changing the way that the Inventory Administrators have access to Inventory functionality in System Configuration. We will be adding an Inventory Admin System Group, to which all users with the Inventory Admin Role will be automatically assigned. The Inventory Admin role will also be permanently assigned relevant privileges for the management of Inventory including all Container and Location related privileges. If Administrators would prefer that current users with the Inventory Admin role do not have all of these privileges, they should create a new Role for these users and assign the desired privileges. This change will be available in a future release. Administrators and users should also note that due to an upcoming change in our Chemical Drawing capability, Chemical Drawings will not load in versions of Safari older than 16.3. We strongly recommend that all users always use the most up to date version of their browser. Administrators are recommended to subscribe to the channels within our support news site found at https://informatics-support.perkinelmer.com/hc/en-us/categories/360004446171-Support-News which contains more information about releases and other pertinent product information. This content is anticipated for release on our Production E3 environments, and for Private Cloud customers on our deferred release schedule, in July 2023. Further Details The following improvements are only available to users and administrators of Signals Notebook Standard and Private Cloud and are unavailable as part of Signals Notebook Individual Edition. Materials The additional Chemically Aware Libraries previously released in beta are now available to all administrators. Administration Organizations who had enabled authentication for integrated applications via a Bearer Token Exchange can now view the users with active Bearer Tokens. A display of the active tokens per user per client (Application) is provided in the Administrative page, SNConfig. The admin can choose to expire all short term bearer tokens for a particular user, or for all short term tokens for all users across all applications across all clients. All long or short term tokens for a selected user and client can also be expired. Administrators can also now allow multiselect for external list fields as can currently be done for other list fields. As with internal references, the additional information/properties for the external attribute appears in a preview when the user hovers over the information (“i”) icon. Integrations & APIs We have added an endpoint PUT/chemicaldrawings/{eid}/reaction to allow developers to replace the underlying .cdxml file in a ChemDraw Document element. The existing .cdxml file can be downloaded via the GET/chemicaldrawings/{eid}/reaction endpoint, modified with any desired changes and replaced. This allows deletion, addition or editing of reagents and/or products. Edits to existing reagents and/or products will in most cases results in any end user entered data in the stoich tables being reapplied to the new structure. We have also added the new endpoint GET/materials/{eid}/report to allow information on the total amount of material assets or batches in Inventory. The following capabilities are in beta and are only available to users and administrators of Signals Notebook Standard or Private Cloud upon request. Please contact your account representative or our support team if you would like access to the following features. They are unavailable as part of Signals Notebook Individual Edition. Materials Tables Materials Tables enabled for registration now support several actions in bulk. A table can be populated with multiple rows of data prior to registration of each item. Simply select all or some of the rows and utilize the bulk actions menu to register. If any registration events fail in a bulk action, the user will be notified with row level errors. These events can be filtered for inspection by clicking on the ID column and selecting the type of error event. Mousing over the error icon gives the user an indication of the type of error that occurred. In this example, both rows are missing required fields. Users may also edit existing items in bulk. Select the items to be edited and then use the Bulk Actions Menu to Edit those rows. Copy and paste actions can be used to quickly fill out a column of data. The user can close the edit mode from the Bulk Actions menu or by navigating away from the table will move the table out of the edit state. Bulk actions include registration of new Materials as well as clearing or deleting rows without IDs. Rows with IDs can be deleted in bulk as well. Users may also import a CSV to populate the Material table. CSVs with IDs will look up existing registered Materials while those without CSVs will populate the rows for supported fields. If a field fails to map to the table or if the field is not supported, the user will be notified and prompted to map or resolve the issue. Materials tables can be downloaded as a CSV and we have also added an ability to copy selected rows to the clipboard with or without column headers or to copy just the Material IDs themselves. Inventory When users have linked containers and used the Inventory Decrement cell in the Chemical Drawing and then choose to delete the Chemical Drawing or the Experiment, a warning will show to let the user know that they may be making a change to the Inventory container(s) that they did not desire to do: Users can now display Total Amount of containers in Assets without Batches in Materials Library. Users can click the down arrow next to the totals to change the units if desired: Worksheets Administrators can now add properties of type List and Multivalue List to Worksheets. These lists are self contained within the Worksheet. Administrators can also define that text fields can contain multiple rows of data. Multi row text data can be designated as a Rich Text field in the property dialog. Once added the end user can add more detailed textual descriptions into such fields. Administrators can also define that certain fields are locked once content has been entered. In order to change the value, the end user must unlock the field, make a change, and provide reasons to be recorded for the change. The administrator can define a list of preconfigured reasons for the user to choose from. 23.1 January 2023 (Update to E3 in July 2023) + What’s New This version 23.1 release of Signals Notebook brings improvements to bookmarks and the ability to get data into admin defined tables. Admins can now change the understanding and display of aromatic compounds on import. We have continued to make improvements to our ongoing Worksheets beta and have added new beta features for Inventory around deprecating amounts and calculating total amounts in Containers. Some of the existing beta capabilities for Materials are also now on general release and available to all administrators. Finally, we have also fixed a number of small bugs. The following improvements are only available for users of Signals Notebook Individual Edition, Signals Notebook Standard and Signals Notebook Private Cloud * Usability * * – Share bookmarks The following improvements are only available for users of Signals Notebook Standard and Signals Notebook Private Cloud * Chemistry * * – Convert mol or SMILES to aromatic or alternating single & double bonds * Admin Defined Tables * * – Match columns on importing csv files * Inventory * * – Scan Location Barcodes * – Decrement Inventory containers from stoichiometry table (beta) * – Total Amount in containers displayed in Materials (beta) * Materials * * – Creation of lots/batches with the Material Table (beta) * – Bulk export enhancements (available to all administrators) * – Export of materials by ID (available to all administrators) * – Bulk update of Materials (available to all administrators) * Integrations & APIs * * – Convert export of mol files to aromatic or alternating single & double bond format * – GET/Materials includes sequence field values for Primers * – Endpoints for Worksheets * Worksheets (beta) * * – Search of Worksheet properties * – Number with unit fields We also fixed several small bugs in this release. Details of the enhancements are described below. The following OnDemand videos for Signals Notebook End Users are now available * Adding to the Reagents Materials Library Administrators should note we have updated our adherence to the SCIM standards. The field “displayName” for the ResourceType Group is now be required. Additionally the field “value” in the “members” multivalue attribute is also required. Any calls to SCIM endpoints in our public APIs will now require these values and will fail if the values are absent. Administrators should change their API calls to incorporate these values if these values are not already included. Administrators should note that as part of the new bulk export enhancements we added a new Export Materials privilege. This privilege is enabled for the Standard User and System Administrator roles only. System Administrators can optionally add or remove this privilege from any role except the System Administrators role. New tenants will not have this privilege enabled for the Standard User role by default. This privilege was enabled in 22.10 but erroneously left out of the What’s New for that version. Administrators are recommended to subscribe to the channels within our support news site found at https://informatics-support.perkinelmer.com/hc/en-us/categories/360004446171-Support-News which contains more information about releases and other pertinent product information. This content is anticipated for release on our Production E3 environments, and for Private Cloud customers on our deferred release schedule, in July 2023. Further Details Usability Users are now able to share bookmarked search queries with other users and groups of users in their tenant. If a user has a query/bookmark they want to share with other users or groups, they can select the “Share Search Query” option now available on their bookmarks under the “Manage Bookmarks” page. The user can then select the groups and users they wish to send the search query. The receiving user gets a notification with a link to the search query in their In-App notifications. These notifications are currently In-App only and are not sent via email. They can be activated or deactivated by selecting the “In-App” option for “When someone shares an item with me” under the notification settings. The receiving user can add the shared query to their own bookmarks by selecting the link in the notification to bring up the shared search query and bookmarking the search themselves. The following improvements are only available to users and administrators of Signals Notebook Standard and Private Cloud and are unavailable as part of Signals Notebook Individual Edition. Chemistry Administrators can now define that chemical structures containing delocalized rings, imported from mol or SMILES formats, can be converted from aromatic to alternating single and double bond representation, or visa-versa. This setting will be applied to structures pasted into a ChemDraw document that are in SMILES or mol format, or when structures are imported via SDFile. The setting will not apply to imported cdx or cdxml files. For example if the setting is changed to “Alternating Double/Single Bonds”, pasted or imported SMILES strings or mol files that have an aromatic representation will be converted to display in alternating single and double bonds. Admin Defined Tables Upload csv to ADTs has been improved to accept data in hidden ADT columns and allow for mapping of columns if columns in the csv cannot be automatically mapped to columns in the ADT. Csv columns are mapped automatically based on column name, order and data type. If the csv has columns that cannot be automatically, a modal pops up allowing the user to manually map the unmapped columns. If the user does not map all of the columns and opts to import the csv without all columns mapped, only mapped columns will import. Inventory Users can now scan the barcode of a location in addition to the name type ahead. User can toggle between the barcode scan icon and the location icon to choose which to select the location: The scan of the location barcode is in all the workflows where the location is required. Materials Enhanced bulk export capabilities are now available to all systems without request. This enables export of up to 5000 items from the Materials Smart folder. There is now the ability to export by Asset or Batch. Previously users were restricted to export of 50 items at the Asset level and the export included all batches. There is also a new option to export a CSV of Compounds or Reagents (SNB). This export will include IDs and properties but will not include any chemistry data. If the user leaves Signals Notebook during the export process they may retrieve downloads from the Bulk Export section of the Materials Bulk Results, accessed from the user menu. Note that a maximum of 50 results will be stored in the system and results will be stored for only 60 days before being purged from the system. The Export by ID feature is now available to all systems without request. Users can submit a list of Material IDs for a given library to retrieve the download. IDs must come from a single library but can include Asset or Batch ids for a given library. Compounds and Reagents (SNB) libraries can be downloaded as an SDF or CSV. Bulk update of materials is now available to all systems without request. The update applies to a single type of Material per action and must include IDs that map to existing materials. The user selects fields to update after including an appropriately formatted CSV file. There is also an option to clear non-required fields during the update. Bulk updates will include reports under the Materials Bulk Results. A file can be downloaded to understand why any updates were unsuccessful. Up to 50 results will be saved in the system and all results older than 60 days will be automatically purged. Integrations & APIs We have enhanced our API endpoints that allow export of structures in various chemical formats to allow conversion to either aromatic or alternating single and double bonds. The aromaticRepresentation parameter applies to endpoints such as GET/stoichiometry/}eid}/{rowid}/structure. The parameter applies only when exporting to mol or SMILES formats. The GET/materials/{eid}/properties endpoint has been enhanced with a parameter to include sequence information in the response. This enrichSequence parameter will allow the sequence property type data to be included in the response from libraries that utilize this property. This does not apply to when the sequence is determined from adding a sequence based file. We have also added a GET/worksheet and PATCH/worksheet endpoint. These endpoints will be visible regardless if you have activated the Worksheets beta but will not be usable without having done so. The following capabilities are in beta and are only available to users and administrators of Signals Notebook Standard or Private Cloud upon request. Please contact your account representative or our support team if you would like access to the following features. They are unavailable as part of Signals Notebook Individual Edition. Inventory Users will now be able to decrement amounts from Signals Inventory containers from the stoichiometry table. Note: This functionality is not available in Parallel Experiments. Administrators will notice that the Inventory Decrement column is available in the Chemistry Settings and hidden by default. The Clear value when element is copy-pasted is permanently defaulted to be checked. Administrators can make appropriate adjustments depending on if Signals Inventory is in use: When users add Material or Sample containers to the Chemical Drawing, the Inventory Decrement cell will be available. When users type an amount into the Inventory Decrement cell, the amount will automatically be deducted from the container. Users will see a green checkmark in the bottom of the table. If the incorrect unit is used, the user will see a red x in the bottom of the table and will need to correct the action for the correct decrement to be completed. Previous to typing an amount into the Inventory Decrement cell, the container had 0.5 g, the Current User was Unassigned and the Status was AVAILABLE: After typing into the Inventory Decrements the container amount is updated, the Current User is changed to the signed in user and the Status changes to “IN USE”. If the decrement typed is larger than what Inventory has recorded, the user will be able to complete the decrement, but the container will automatically have the Status set to EXHAUSTED: If the user deletes the row or the drawing and has a value in the Inventory Decrement field, a warning will appear: If the user closes the experiment but forgets to type a value into the Inventory Decrement, they will get a warning. Users can continue and close the experiment or cancel out and go back and update the amounts in the Inventory Decrements: Users will also now see the Total Container Amount of a Material reported on the Material’s details page. The total amount is reported as a sum based on the unit type selected. For example, if the material has containers in both mass and volume, the amount total will add all the mass containers and report it in grams. The same is true of volume and the total will be reported in milliliters: Count will be reported as a number with no units. The Total Amount per Lot or Batch is reported in the Container Amount column on the Batch/Lot page: Containers that are in the Exhausted, Disposed or Final Disposed status will not be counted in the Amount Total. Containers in the Disposed or Final Disposed Status will no longer show by default in the expanded container view: To view disposed containers or to hide empty columns use the filter icon in the top right corner of the table: Materials With the beta feature enabled it is possible to use Materials tables configured for registration to also create batches/lots of an existing material. This is possible for all Materials with Asset/Batch configuration, including Compounds and Reagents (SNB). Admins must first enable a given Material Table for registration or batch creation: To create a new batch of any given material, users must first add a valid item to an existing Materials table. The user will then see a new option to create a batch/lot from the menu item next to the item ID. A modal will then open and allow the user to enter metadata and specify the number of batches to create. Once completed, the batches will appear in the Materials Table with IDs. Note, Compounds and Reagents (SNB) cannot be edited from the materials table. To update values after creation the user will have to navigate to the individual batch in the Materials Smart Folder. Worksheets We have enabled search on Worksheets. Worksheet elements can be retrieved via searching for Type=Worksheet. Additionally the properties filled in within worksheets can also be searched, each property is prefixed with “Worksheet”. We have added a new property type for numbers with units. Administrators can now define united number fields in Worksheets, whereby they select the property type, select the measure type, such as mass, and can define a default unit, such as grams. Please click below to go to the archiving monthly update page 2022 Monthly Updates > 2021 Monthly Updates > 2020 Monthly Updates > 2019 Monthly Updates > 2018 Monthly Updates > 2017 Monthly Updates > Join the Signals Notebook Quarterly Connect+ Webinar for Latest Updates Register Now * * * * © 2023 Revvity Signals Software, Inc. All Rights Reserved. Revvity Signals Software, Inc. | 940 Winter Street | Waltham, MA 02451 USA | www.revvitysignals.com ShareThis Copy and Paste