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× ClickBank is the trusted retailer for jointgenesis.com. If you aren't completely satisfied with your purchase, let us know. We'll make it right. Your satisfaction is guaranteed! × Joint Genesis Dr. Weis, M.D. Ingredients FAQ Impact local_mall Order Now * Joint Genesis * Dr. Weis, M.D. * Ingredients * FAQ * Impact * local_mall Order Now Click for sound play_arrow As Featured On: BIODYNAMIX® is not endorsed by, sponsored by, or affiliated with any of these organizations. Join the Thousands of U.S. Seniors Enjoying Comfortable, Flexible and Youthful Joints Thanks to Joint Genesis™ From the Desk of: Dr. Mark Weis, M.D. In the mountains of Japan, there exists a small and remote village called Yuzurihara. It's a village where 70, 80, and even 90 year olds are still able to comfortably squat, twist and bend for up to 8 hours a day to farm their rice crops. They plow their fields without the help of modern machinery, and they continue to harvest their fruit and vegetables by hand. In fact, so-called "wear and tear" barely seems to exist in the joints of these Japanese seniors. The secret lies in the village's fertile soil where a unique type of purple sweet potato grows. It's called the satsumaimo, and it's rich in a joint-supporting molecule called hyaluronan. How does hyaluronan support joint health? Hyaluronan's crucial role in joint health is to absorb water so it can give your synovial fluid its naturally thick, lubricating, and jelly-like quality. The synovial fluid sits inside the joint cavity where it hydrates, cushions and nourishes the cartilage tissue and helps to support a healthy inflammatory response, promoting optimum joint comfort and flexibility. The problem for most of us is that our joints begin to lose hyaluronan at an accelerated pace once we pass 30 years of age. The result is that our synovial fluid thins and dries out, the cartilage becomes exposed, and an unhealthy inflammatory response takes hold. At which point, typical age-related joint issues arise. But thanks to the satsumaimo – and other hyaluronan-rich foods that make up much of their diet – those Japanese villagers are able to support healthy hyaluronan levels. This means their synovial fluid remains thick and healthy. As a result their cartilage tissue stays lubricated, cushioned and nourished, and their joints enjoy a healthy inflammatory response. According to new scientific research… This is why joint concerns are so rare in the aging population of Yuzurihara. Hyaluronan is now deemed so important that world-leading joint health expert Dr J.R. Levick of St George's Hospital Medical School at the University of London has dubbed this molecule: "The guardian of your joints"… and "their key protective agent". This has now been supported by a study published in the esteemed Nutrition Journal which found that people with age-related joint issues have: "Diminished hyaluronan concentrations in their synovial fluid". The discovery of these Japanese villagers, and the molecule that keeps their joints so supple and youthful despite their advantage years, gave rise to an idea: The creation of an advanced and research-backed formula capable of keeping our synovial fluid thick and healthy, enabling all of us to enjoy comfortable and supple joints, long into old age. With that, Joint Genesis™ was born. About Joint Genesis™ Joint Genesis™ is a unique approach to joint health that finally addresses what growing research now suggests is the origins of age-related joint decay: the loss of hyaluronan as you get older. So you can once again cushion and lubricate those stiff and dehydrated joints, nourish your cartilage tissue, and support a healthy inflammatory response... Allowing you to enjoy a new beginning, and start living life with a spring in your step and a smile on your face again! Our proprietary formula is the first in the world to combine four research-backed joint-supporting nutrients with Mobilee®, an advanced and patented ingredient shown to multiply hyaluronan molecules in the synovial fluid by a factor of 10. This cutting-edge ingredient blend supports joint health in a novel way: by rehydrating and thickening up the naturally jelly-like synovial fluid in our joints. Scientific research and countless clinical studies have now shown, when you rehydrate and thicken up your synovial fluid, you promote: Nourished, lubricated joints A healthy inflammatory response Optimum joint comfort Youthful mobility and flexibility And a happy, active life! Dave Sherman Arizona star star star star star “Joint Genesis has made a great change in my life. I'm able to play my guitar again and worship God the way I’m supposed to. And I just laid three rooms of tile in my house that I didn’t think I’d be able to do. The turnaround has been quite remarkable!” Mary Mazur Michigan star star star star star “My power walking exercise sessions are much smoother. I've improved my speed and my mobility and flexibility. And I can go and exercise without feeling stiff afterwards.” Pat Arola Florida star star star star star “I'm able to go on long walks and swim half an hour a day which I couldn't do before. I'm much more confident about being able to travel and go on long hikes and keep up with the rest of the group.” Marcos Wessolossky Florida star star star star star “It is a huge difference now. To be able to move and have flexibility and feel okay! I know I can be there for my family now, go to work and do everything I need to do.” Ann Jagodzinski Wisconsin star star star star star “When I wake up my knees don’t hurt, which is great! I feel less stiffness and overall it feels much better. Joint Genesis has really helped me get moving in the morning.” Dr. Mark Weis, M.D. BioDynamix® is headed by Dr. Mark Weis, M.D. an award-winning physician and medical consultant. Dr. Weis completed his medical school and postgraduate ctraining at The University of Kansas School of Medicine. In the years that followed he worked as a primary care and emergency physician at a rural hospital in Kentucky, where he also served as Chief of Staff. Dr. Weis later served his country as a civilian physician for the U.S. Army at the Wounded Warrior Clinic at Fort Knox, Kentucky; as a General Medical Officer at Fort Riley, Kansas; and as the Lead Primary Care Physician for the U.S. Army's RESPECT-Mil PTSD and Depression Screening Program at Walter Reed Army Medical Center. Today, Dr. Weis is the Medical Research Director at BioDynamix®, where he investigates and shares innovative health solutions that are found in nature, and backed by real research. The Joint Genesis™ Formula Mobilee® Mobilee® Mobilee® is the star ingredient in Joint Genesis™, and as more and more research shows, the key to optimum joint health at any age. After being rigorously tested in 14 randomized, placebo-controlled and double-blind clinical trials – the gold standard of clinical trials – an 80mg dose of Mobilee® has been shown to: MULTIPLY HYALURONAN LEVELS IN THE JOINTS BY A FACTOR OF 10. In one of those trials, published in the medical journal Clinical Nutrition Supplements, taking 80mg of Mobilee® each day for a period of 6 months was shown to promote joint comfort. More importantly, those comfort levels continued to steadily increase for the entire 6 month study. In other words, their results got better and better the longer the study went on. These results were repeated in numerous other published clinical studies too, where supplementing with 80mg of Mobilee® each day was found to support joint comfort, physical function, flexion and extension, as well as promoting muscular strength. French Maritime Pine Bark French maritime pine bark Although Mobilee® works wonders for your joints on its own, we discovered that its joint-supporting power is strengthened further when combined with another rare and expensive ingredient. And this is where Joint Genesis™ truly shines, and real, life-changing progress can be felt. This rare ingredient is the bark of a French maritime pine tree. In multiple studies, this super-antioxidant has proven to be one of the world's most powerful ingredients for supporting a healthy inflammatory response, and promoting joint comfort and physical function. And it does it rapidly – which is why French Maritime Pine Bark is the perfect complement to Mobilee®. The reason these two ingredients work so well together was outlined in a recent clinical study published in the medical journal Nutrients. In the study, scientists found that the powerful antioxidants in French Maritime Pine Bark are distributed directly into the synovial fluid, helping to maintain a healthy inflammatory response in the joint space... Meaning you can expect to enjoy greater relief, for longer! Ginger Root Ginger Root Like French Maritime Pine Bark, ginger is a potent antioxidant and decades of studies support its efficacy in promoting a healthy inflammatory response in the joint tissue. A study published in the Journal of Medicinal Food found that a ginger extract was effective in reducing knee pain in patients with age-related joint issues. In doing so, ginger helps to boost the effectiveness of Joint Genesis™ and promote greater joint comfort, flexibility and mobility. Boswellia Serrata Boswellia Serrata Another ingredient that helps to further strengthen the results delivered by Mobilee® and French maritime pine bark is Boswellia Serrata, a tree that originates in India. The extract derived from the gum resin of the bark of the Boswellia tree has been proven in multiple studies to promote a healthy inflammatory response in the joint tissue, helping to support joint comfort and joint function. Added to that, a study in the medical journal Phytomedicine investigated the effects of a combination of French maritime pine bark and Boswellia serrata on patients with age-related joint pain. The results showed that the combination significantly improved joint pain, stiffness, and physical function. BioPerine® BioPerine® To round off the formula and help ensure the strongest and fastest possible results, Joint Genesis™ also includes BioPerine®, another advanced and patented extract obtained from black pepper fruits that helps boost the absorption of the other ingredients in the formula. As a result, this unique and powerful blend of ingredients includes everything you need to help support your joints, enjoy comfortable movement, and delight in the renewed flexibility of your youth! Sara Minter Texas star star star star star “This stuff is amazing! I’ve gained more mobility. And when cooking for the elderly people in my neighborhood I can perform those tasks easier. It just revives my whole body.” Luz Florez Washington D.C. star star star star star “I am feeling more confident now. I love to cook and I can enjoy cooking again because I don’t have this discomfort in my hands. My life has changed a lot.” Chris Arthur Oregon star star star star star “I can move better, I'm more flexible, and I'm enjoying myself more! Now I feel confident that I can go for a walk, I can keep up with friends and take the dog around the block.” Gregory Haston Missouri star star star star star “After taking Joint Genesis I can do bends, put on my shoes, get where I'm wanting to go without discomfort, and not be worrying about limping or getting in and out of the car.” Lou Deutsch Maryland star star star star star “Since taking Joint Genesis I would say I've had between a 30 and 40% improvement, giving me more mobility and making it easier to get in and out of cars and climb stairs.” Imagine continuing to enjoy flexible, comfortable joints… To be able to bounce out of bed each morning and sprint down the stairs without feeling an agonizing jolt with every step, because your knees and hips are properly cushioned and lubricated. Imagine grabbing a shirt or pants, and buttoning them up with the supple wrists and flexible fingers of a 20-year-old. To comfortably sit crossed-legged on the floor with your grandkids while you happily play board games with them. Or kneel down on the ground to tend to the roses without fearing that you might get stuck down there, frozen in agony. But more than that, Joint Genesis™ will finally allow you to reach a level of joint comfort that helps you strengthen relationships. First; with your friends and loved ones, because you're no longer in discomfort or being looked upon as old and fragile. And second; with yourself, because you can finally enjoy your freedom and independence, and live life on your terms. Just like so many of our happy customers are doing right now. In fact, when we first launched Joint Genesis™, we were confident that it was about to change lives. And it hasn't disappointed! Cutting-Edge Research, State-of-the-Art Manufacturing As you've seen, we've spared no expense in developing this one-of-a-kind formula, and willingly cut into our own profits to ensure you receive only the very best science-backed ingredients in clinically-effective dosages. First with Mobilee®, a patented and highly prized ingredient due to its unique ability to increase your body's production of joint-supporting hyaluronan by a factor of 10... And then with French maritime pine bark, which works in tandem with Mobilee® to give you even stronger results. So with that said, we understand that price might be a concern for you right now. Especially when you consider something else too: Unlike many other joint formulas, we're committed to sparing no expense on the manufacturing process either. Joint Genesis™ is meticulously produced following current Good Manufacturing Practices (cGMP) in our state-of-the-art, climate-controlled and FDA-inspected facility, right here in the USA! This guarantees the strictest standards in terms of quality control to ensure only the finest, purest ingredients, in the exact dosages listed on the bottle. Added to that, we're committed to creating a product that as many people as possible can benefit from, which is why Joint Genesis™ is vegetarian and vegan-friendly, as well as being free from gluten, dairy, nuts, soy, egg, crustaceans, and of course, nasty BPAs and GMOs. It's a complex, time-consuming process to produce a premium product like Joint Genesis™, which is naturally reflected in the premium price. But don't worry, because right now, you have the chance to take advantage of the following: Special Discount Pricing on Joint Genesis™ Here at BioDynamix®, we understand how frustrating joint issues can be, and how quickly they can rob you of the things that used to bring you joy, and make your world seem so much smaller. For that reason we wanted Joint Genesis™ to be within reach of as many people as possible. Which is why we're giving you the opportunity to try a 30-day supply of Joint Genesis™ for the special one-time price of just $129 $59! That's a huge saving off the regular price. But wait – it gets better! Before you place your order, it's important to remind you that more and more scientific research into the ingredients inside this formula demonstrate that the longer you take Joint Genesis™, the better your results. Remember, those clinical trials of Mobilee® – the key ingredient inside Joint Genesis™ – took 6 months, and the levels of joint comfort and joint function kept increasing the longer those trials went on. Similarly for French maritime pine bark, where countless studies have shown that continuous use helps to support a healthy inflammatory response and promote joint comfort and joint function over time. So the science is clear. The longer you take Joint Genesis™, the thicker and healthier your synovial fluid becomes, and the more comfortable, supple and flexible your joints will feel. So to make sure you experience the best results possible, we've created a special bundle plan offering both 90-day and 180-day packages at massive discounts, meaning you can save even more money. If you can still see all three money-saving options below, I recommend you take advantage of this special pricing now, and make sure there's no break in your progress over the next few months. Because the truth is: You'll never be able to order Joint Genesis™ cheaper than today. What's more, Joint Genesis™ will never be available in stores either. We're only able to offer today's hugely discounted pricing because we're deliberately bypassing the stores, which enables us to cut out the middleman and pass those savings onto you. Furthermore, rest assured this is a one-time payment. There are no subscriptions or hidden charges of any kind. We've always hated that stuff as much as you do. And you don't need to worry about the ordering process either. When you select your savings, you'll be sent through to our secure ordering page, which uses 256-bit encryption technology – the same technology used by the world's biggest banks. So you can be completely confident your information is 100% safe and secure. And if you're still unsure whether Joint Genesis™ will work for you, we completely understand. Which is why your order is backed by the following: 180-Day "Empty Bottle" Satisfaction Guarantee We're so confident you'll be head-over-heels thrilled with the results you get that we're giving you a full 6 months to try Joint Genesis™ for yourself, completely risk-free, regardless of the package you choose. If you change your mind for any reason, simply contact our friendly customer support team, and they'll refund 100% of the purchase price. Contact details will be on the packaging. Added to that, our "empty bottle" guarantee means we will refund every penny even if you've used up your entire supply. That's how confident we are that you'll be 100% satisfied, and won't be asking for your money back! So there really is nothing to lose by putting Joint Genesis™ to the test today, and a happier, more active future to gain. Go ahead and select your savings from the options below. Dr. Mark Weis, M.D. SPECIAL INTRODUCTORY OFFER: Select Your Savings 6 BOTTLES 6-Month Supply + 2 FREE Bonuses $59 $39PER BOTTLE ADD TO CART TOTAL: $234 +FREE USA Shipping +FREE United States Shipping 180-Day Guarantee 1 BOTTLE 1-Month Supply $59PER BOTTLE ADD TO CART TOTAL: $59 +$9.95 USA Shipping +$19.95 United States Shipping 180-Day Guarantee 3 BOTTLES 3-Month Supply + 2 FREE Bonuses $59 $49PER BOTTLE ADD TO CART TOTAL: $147 +FREE USA Shipping +$19.95 United States Shipping 180-Day Guarantee search GET 2 FREE BONUSES WORTH $59.90 WHEN YOU ORDER A 3 OR 6 MONTH SUPPLY Bonus #1 17 Joint-Supporting Smoothies Value: $29.95 | Today: FREE Learn more arrow_drop_down To help accelerate your results we will send you our brand-new eBook consisting of 17 joint-supporting smoothie recipes when you order a 3 or 6 month supply of Joint Genesis™. All of these smoothies help to calm inflammation, giving you faster, more noticeable relief. They take just a few minutes to prepare and taste great, making them a great option for a quick breakfast or afternoon snack! Let’s be clear: drinking these smoothies isn’t something you have to do. But if you’d like to accelerate the transformation in your joint health, this is the easiest way to do it. You can even take Joint Genesis™ with one of these smoothies each morning! Bonus #2 Youthful Joints For Life Value: $29.95 | Today: FREE Learn more arrow_drop_down To help turbocharge the results you see and feel from Joint Genesis™ we will also send you Youthful Joints for Life when you order a 3 or 6 month supply. This step-by-step guide provides a proven path to healthy joint function whatever your age via simple, yet powerful habits you can adopt from the comfort of your own home. When you combine Joint Genesis™ with Youthful Joints for Life you will have everything you need to start enjoying healthy, supple and flexible joints, and maintain those results for as long as you want! Charlene Hernes Indiana star star star star star “I feel less stiffness and my mobility and flexibility has improved. I feel more joyful, more confident, and more hopeful about the future.” Patricia Bass Virginia star star star star star “The discomfort is decreasing. It's not as often and it's not as intense. It makes me hopeful and it makes me happy to think that this can actually go away!” Vanessa Maler Florida star star star star star “I feel so much better. I'm more active, I'm able to do the activities that I love to do, like walk my dogs in the park, swim, do my yoga and my gardening.” Albert Peralta Arizona star star star star star “Now when I sleep I don't wake up in the middle of the night with my shoulder. It really has improved. I don’t have the words to describe how much better I feel!” Michael Akin Texas star star star star star “I can move my neck a lot more freely. I ride a motorcycle so that makes a huge amount of difference. It's a great improvement.” Roberta Evans California star star star star star “I can do yoga a lot easier. And when I go on a hike I'm not so stiff after. Joint Genesis works. It definitely takes away the stiffness in my legs, for sure. It's a definite game changer.” Sue Kuligowski Illinois star star star star star “I'm able to walk longer, ride my bike longer, run a little bit, and do my swimming that I enjoy. It seems like the flexibility has come back to my right knee.” JOINT GENESIS™ FAQ If you're still here, that tells me two things: 1. You understand how crucial proper joint function is to your health and happiness, and… 2. You still have a few questions. It's perfectly fine to have questions. I'm glad you do. So let me answer them so you can feel comfortable trying out Joint Genesis™ for yourself. Here are the answers to a few of the most common questions we receive about Joint Genesis™. HOW DO I KNOW JOINT GENESIS™ WILL WORK FOR ME? -------------------------------------------------------------------------------- Ok, while your joint discomfort may be slightly different to that of others, one factor is likely the same: The loss of Hyaluronan molecules from your synovial fluid, or "Joint Jelly", as you age. This loss of Hyaluronan thins and dries out your synovial fluid, meaning your cartilage loses its natural cushioning, becomes dehydrated, and is starved of vital oxygen and nutrients… Which results in cell death, and cartilage breakdown… Followed by inflammation of the joint. The key ingredient in Joint Genesis™ – Mobilee® – works by replenishing your synovial fluid with hyaluronan. Mobilee's® hyaluronan is 10 times more effective than standard hyaluronan used in previously successful clinical studies. This helps to quickly lubricate and cushion the joint, nourish the cartilage tissue, and soothe inflammation. In studies, 80mg of Mobilee® resulted in a clinically-documented reduction in joint discomfort and swelling, which kept improving each and every month for the entire six month trial. As well as "significant" improvements in physical function, flexion and extension… Muscle aches, muscular strength, and quality of life. Crucially, Joint Genesis™ also includes French maritime pine bark. This super-antioxidant is one of the world's most powerful active ingredients for supporting a healthy inflammatory response. And has been shown in multiple studies to soothe inflammation and joint discomfort, combat stiffness and swelling, and support improved joint function. What's more, French maritime pine bark works perfectly in tandem with Mobilee® because the antioxidants have been shown to distribute directly into your synovial fluid, or Joint Jelly, giving you stronger results. I'VE TRIED OTHER JOINT HEALTH SUPPLEMENTS IN THE PAST. WHY HAVEN'T THEY WORKED FOR ME? -------------------------------------------------------------------------------- Most other joint supplements don't contain hyalouronan—and they certainly won't have it in its patented form: Mobilee®… Which means they never get to the root of the problem. Neither do they contain the unique combination of Mobilee® and French maritime pine bark, which helps to further support relief and promote healthy joint function. CAN I GET MY MONEY BACK IF I'M NOT 100% HAPPY? -------------------------------------------------------------------------------- Absolutely! We're so confident in our product that BioDynamix offers one of the most generous guarantees in the industry. Regardless of the package you choose today, you are protected by our 6-month money-back "empty bottle" guarantee. This means that if for any reason you don't experience life-changing results or you simply change your mind for any reason at all, we will issue you a 100% no-questions asked refund. Plus, we'll refund every penny even if all the bottles are all empty! HOW MANY BOTTLES SHOULD I ORDER? -------------------------------------------------------------------------------- To help you stock up and save more money, we've created a special bundle plan consisting of 3 and 6 month packages to go alongside the one month starter option. This is because countless clinical studies of our key ingredients Mobilee® and French maritime pine bark – together with the experiences of our customers – show the longer you take Joint Genesis™, the more effective it becomes. That's why I personally recommend that you stock up on the 3 or 6 month option while this special offer is running. This will help ensure there's no break in your progress, so you can enjoy the best possible long-term results. And don't forget that Joint Genesis™'s two-year shelf life means there's no risk in stocking up. HOW LONG WILL IT TAKE TO RECEIVE MY ORDER? -------------------------------------------------------------------------------- Your order will be shipped out right away and will arrive at your door within 5-7 business days (for U.S. locations). Orders placed outside the U.S. may take up to two weeks to arrive. HOW SHOULD I TAKE JOINT GENESIS™? -------------------------------------------------------------------------------- Take one capsule per day with water, preferably in the morning. Each bottle comes with enough capsules for a 30-day supply. CAN I TAKE JOINT GENESIS™ IF I HAVE FOOD ALLERGIES? -------------------------------------------------------------------------------- Yes, you can! We wanted to ensure as many people as possible would be able to enjoy the benefits of Joint Genesis™, so our formula is vegetarian and vegan-friendly, and free from gluten, dairy, sugar, nuts, soy, egg, and crustaceans. It's also free of GMOs, BPAs, and is "guaranteed pure". This is because Joint Genesis™ is is produced following current Good Manufacturing Practice (cGMP) standards in our state-of-the-art, FDA-inspected facility right here in the USA, which ensures the purest product, free from any potential contaminants. IS THIS A ONE-OFF PURCHASE OR WILL I BE BILLED FOR MORE BOTTLES LATER? -------------------------------------------------------------------------------- This is a one-off purchase of Joint Genesis™. You will not be billed again, nor entered into any kind of auto-ship program. WHAT ARE THE INGREDIENTS INSIDE JOINT GENESIS™? -------------------------------------------------------------------------------- Here's a complete list of all the research-backed ingredients you get in every serving of Joint Genesis™. search SPECIAL INTRODUCTORY OFFER: Select Your Savings 6 BOTTLES 6-Month Supply + 2 FREE Bonuses $59 $39PER BOTTLE ADD TO CART TOTAL: $234 +FREE USA Shipping +FREE United States Shipping 180-Day Guarantee 1 BOTTLE 1-Month Supply $59PER BOTTLE ADD TO CART TOTAL: $59 +$9.95 USA Shipping +$19.95 United States Shipping 180-Day Guarantee 3 BOTTLES 3-Month Supply + 2 FREE Bonuses $59 $49PER BOTTLE ADD TO CART TOTAL: $147 +FREE USA Shipping +$19.95 United States Shipping 180-Day Guarantee search SCIENTIFIC REFERENCES Centers for Disease Control and Prevention. Morbidity and Mortality Weekly Report. March 10, 2017. Vol. 66. No. 9. Sawitzke AD, Shi H, Finco MF, Dunlop DD, Bingham CO 3rd, Harris CL, Singer NG, Bradley JD, Silver D, Jackson CG, Lane NE, Oddis CV, Wolfe F, Lisse J, Furst DE, Reda DJ, Moskowitz RW, Williams HJ, Clegg DO. The effect of glucosamine and/or chondroitin sulfate on the progression of knee OA: a report from the glucosamine/chondroitin arth intervention trial. Arth Rheum. 2008 Oct;58 (10):3183-91. doi: 10.1002/art.23973. Ian J. Wallace, Steven Worthington, David T. Felson, Robert D. Jurmain, Kimberly T. Wren, Heli Maijanen, Robert J. Woods, and Daniel E. Lieberman. Knee OA has doubled in prevalence since the mid-20th century. Anthropology. August 14, 2017. doi.org/10.1073/ Tamer TM. Hyaluronan and synovial joint: function, distribution and healing. Interdiscip Toxicol. 2013;6(3):111-125. doi:10.2478/intox-2013-0019 Necas, J., Bartosikova, L., Brauner, P., & Kolar, J. (2008). Hyaluronic acid (hyaluronan): A review. Veterinarni Medicina, 53(8), 397–411. doi.org/10.17221 Ingram KR, Wann AK, Angel CK, Coleman PJ, Levick JR. Cyclic movement stimulates hyaluronan secretion into the synovial cavity of rabbit joints. J Physiol. 2008;586(6):1715-1729. doi:10.1113/jphysiol.2007.146753 J R Levick. Physiology, Basic Medical Sciences, St. George's Hospital Medical School, Hyaluronan, the guardian of joints. Physiology News Magazine. [2007]. Issue 67. doi.org/10.36866/pn.67.18 Oe, M., Tashiro, T., Yoshida, H. et al. Oral hyaluronan relieves knee pain: a review. Nutrition Journal 15, 11 (2015). doi.org/10.1186/s12937-016-0128-2 Jung H. Hyaluronidase: An overview of its properties, applications, and side effects. Arch Plast Surg. 2020;47(4):297-300. doi:10.5999/aps.2020.00752 Temple-Wong MM, Ren S, Quach P, et al. Hyaluronan concentration and size distribution in human knee synovial fluid: variations with age and cartilage degeneration. Arth Res Ther. Published 2016 Jan 21. doi:10.1186/s13075-016-0922-4 Nicholls MA, Fierlinger A, Niazi F, Bhandari M. The Disease-Modifying Effects of Hyaluronan in the OA Disease State. Clin Med Insights Arth Musculoskelet Disord. 2017. doi:10.1177/1179544117723611 Tashiro T, Seino S, Sato T, Matsuoka R, Masuda Y, Fukui N. Oral administration of polymer hyaluronic acid alleviates symptoms of knee OA: a double-blind, placebo-controlled study over a 12-month period. Scientific World Journal. 2012. doi: 10.1100/2012/167928. Möller I, Martinez-Puig D, Chetrit C. Oral administration of a natural extract rich in hyaluronic acid for the treatment of knee OA with synovitis: a retrospective cohort study. Clinical Nutrition Supplements 2009. Douglas S Kalman, Maria Heimer, Anita Valdeon, Howard Schwartz and Eric Sheldon. Effect of a natural extract of chicken combs with a high content of hyaluronic acid on pain relief and quality of life in subjects with knee OA: a pilot randomized double-blind placebo-controlled trial. Nutrition Journal 2008 Martinez-Puig D, Möller I, Fernández C, Chetrit C. Efficacy of oral administration of yoghurt supplemented with a preparation containing hyaluronic acid (Mobilee™) in adults with mild joint discomfort: a randomized, double-blind, placebo controlled intervention study. Mediterranean Journal of Nutrition and Metabolism 2013;6:63–68. Sánchez J, Bonet ML, Keijer J, van Schothorst EM, Mölller I, Chetrit C, Martinez-Puig D, Palou A. Blood cell transcriptomics as a source of biomarkers of articular health. Annals of Nutrition and Metabolism 2013;63(S1):538 Moriña D, Solà R, Valls RM, López de Frutos V, Montero M, Giralt M, Papell I, Bernal G, Faba J, Casajuana C, Rodríguez A, Chetrit C, Martinez-Puig, Efficacy of a Low-fat Yogurt Supplemented with a Rooster Comb Extract on Joint Function in Mild Knee Pain Patients: A Subject-level Meta-analysis. Annals of Nutrition and Metabolism 2013;63(S1):1386 Rohdewald PJ. Review on Sustained Relief of OA Symptoms with a Proprietary Extract from Pine Bark. J Med Food. 2018;21(1):1-4. doi:10.1089/jmf.2017.0015 Cisár P, Jány R, Waczulíková I, Sumegová K, Muchová J, Vojtassák J, Duraćková Z, Lisý M, Rohdewald P. Effect of pine bark extract on symptoms of knee OA. Phytother Res. 2008 Aug;22(8):1087-92. doi: 10.1002/ptr.2461. Mulek et al. "Distribution of Constituents and Metabolites of Maritime Pine Bark Extract into Serum, Blood Cells, and Synovial Fluid of Patients with Severe OA: A Randomized Controlled Trial". Nutrients. 2017. Doi:10.3390/nu9050443 Rohdewald, Peter Jörg. "Review on Sustained Relief of OA Symptoms with a Proprietary Extract from Pine Bark." Journal of Medicinal Food. V 21,1 (2018): 1-4. doi:10.1089/jmf.2017.0015 Cisár P, Jány R, Waczulíková I, Sumegová K, Muchová J, Vojtassák J, Duraćková Z, Lisý M, Rohdewald P. Effect of pine bark extract on symptoms of knee OA. Phytother Res. 2008 Aug;22(8):1087-92. doi: 10.1002/ptr.2461. Altman RD, Marcussen KC. Effects of a ginger extract on knee pain in patients with OA. Arthr Rheum. 2001 Nov;44(11):2531-8. doi: 10.1002/1529-0131 (200111) Mashhadi NS, Ghiasvand R, Askari G, Hariri M, Darvishi L, Mofid MR. Anti-oxidative and anti-inflammatory effects of ginger in health and physical activity: review of current evidence. Int J Prev Med. 2013;4(Suppl 1):S36–S42. Bartels EM, Folmer VN, Bliddal H, Altman RD, Juhl C, Tarp S, Zhang W, Christensen R. Efficacy and safety of ginger in OA patients: a meta-analysis of randomized placebo-controlled trials. OA Cartilage. 2015 Jan;23(1):13-21. doi: 10.1016/j.joca.2014.09.024. Yu G, Xiang W, Zhang T, Zeng L, Yang K, Li J. Effectiveness of Boswellia and Boswellia extract for OA patients: a systematic review and meta-analysis. BMC Complement Med Ther. 2020 Jul 17;20(1):225. doi: 10.1186/s12906-020-02985-6. Siddiqui MZ. Boswellia serrata, a potential anti-inflammatory agent: an overview. Indian J Pharm Sci. 2011 May;73(3):255-61. doi: 10.4103/0250-474X.93507. BIODYNAMIX® 7362 Remcon Circle El Paso, TX 79912. Formulated in the USA. For product returns, please see our refund policy Get Started Terms & Conditions Privacy Policy Refund Policy Anti-Spam Policy Affiliates Contact Us ClickBank is the retailer of products on this site. CLICKBANK® is a registered trademark of Click Sales Inc., a Delaware corporation located at 1444 S. Entertainment Ave., Suite 410 Boise, ID 83709, USA and used by permission. 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