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For Scientists.
By Scientists.
Bringing Epigenetics To Life.
Products Services
Chromatin structure provides a foundational roadmap for gene expression,
cellular identity, and disease development. To fully realize the potential of
chromatin research for human health, scientists need dynamic technologies that
can adapt to their needs and enable new paths of discovery.
ABOUT US
With decades of experience and active collaborations in epigenetics research
(see co-authored publications), EpiCypher uniquely understands the challenges
facing this field – and how to solve them. Our scientists are leading the
development of innovative products and high-throughput services that are backed
by a rigorous scientific approach, validated protocols, and quantitative assay
controls.
EpiCypher works with groups spanning academia, industry, and clinical trials.
These experiences inspire us to push technological boundaries, making chromatin
more accessible to answer nature’s most complex and enduring questions. As your
research partner, our team can help take your science to the next level.
Request Info
FEATURED TECHNOLOGIES
EpiCypher is dedicated to creating novel platforms that support innovative
chromatin research. We are constantly expanding our product lines to provide the
latest in quantitative chromatin technology.
CUTANA™ CHIC / CUT&RUN ASSAYS
Versatile chromatin mapping assays with improved sensitivity, throughput, and
costs vs. ChIP-seq.
Learn More
CUTANA™ CUT&TAG ASSAYS
Sister technology to CUT&RUN, developed for specialized epigenomic applications.
Learn More
SNAP SPIKE-IN CONTROLS
Control for all aspects of your chromatin mapping experiment using our unique
spike-in technology.
Learn More
FEATURED PRODUCTS
* Epigenetic Kits and Reagents
* Antibodies
* Nucleosomes
* Proteins & More
CUTANA™ CUT&TAG KIT
Exclusive single-tube workflow allows you to go from cells to sequencing in just
two days
View
CUTANA™ CHIC / CUT&RUN ASSAYS
pAG-MNase and other reagents for high-resoluton mapping of histone PTMs and
chromatin proteins
View
CUTANA™ CUT&TAG ASSAYS
pAG-Tn5 and accessory reagents enable specialized chromatin profiling
applications
View
CUTANA™ CUT&RUN KIT
Includes our streamlined protocol and all the controls you need for robust
CUT&RUN assays
View
CUTANA™ CUT&RUN LIBRARY PREP KIT
Sequencing library preparation uniquely optimized for ultra-sensitive CUT&RUN
assays
View
CUTANA™ CUT&TAG KIT
Exclusive single-tube workflow allows you to go from cells to sequencing in just
two days
View
CUTANA™ CHIC / CUT&RUN ASSAYS
pAG-MNase and other reagents for high-resoluton mapping of histone PTMs and
chromatin proteins
View
CUTANA™ CUT&TAG ASSAYS
pAG-Tn5 and accessory reagents enable specialized chromatin profiling
applications
View
CUTANA™ CUT&RUN KIT
Includes our streamlined protocol and all the controls you need for robust
CUT&RUN assays
View
CUTANA™ CUT&RUN LIBRARY PREP KIT
Sequencing library preparation uniquely optimized for ultra-sensitive CUT&RUN
assays
View
CUTANA™ CUT&TAG KIT
Exclusive single-tube workflow allows you to go from cells to sequencing in just
two days
View
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CUT&RUN ANTIBODIES - CHROMATIN-ASSOCIATED PROTEINS
For transcription factors, chromatin reader proteins, remodelers, and more -
validated directly in CUT&RUN
View
CUTANA™ CUT&TAG ANTIBODIES
Validated for high quality performance in CUT&Tag
View
SNAP-CHIP® CERTIFIED ANTIBODIES
Low cross-reactivity and high binding efficiency in ChIP assays
View
ANTIBODIES COMPLETE LIST
Check out our extensive list of antibodies for CUT&RUN, CUT&Tag, and ChIP-seq
View
CUT&RUN ANTIBODIES – HISTONE PTMS
Proven target specificity and high enrichment efficiency in CUT&RUN
View
CUT&RUN ANTIBODIES - CHROMATIN-ASSOCIATED PROTEINS
For transcription factors, chromatin reader proteins, remodelers, and more -
validated directly in CUT&RUN
View
CUTANA™ CUT&TAG ANTIBODIES
Validated for high quality performance in CUT&Tag
View
SNAP-CHIP® CERTIFIED ANTIBODIES
Low cross-reactivity and high binding efficiency in ChIP assays
View
ANTIBODIES COMPLETE LIST
Check out our extensive list of antibodies for CUT&RUN, CUT&Tag, and ChIP-seq
View
CUT&RUN ANTIBODIES – HISTONE PTMS
Proven target specificity and high enrichment efficiency in CUT&RUN
View
CUT&RUN ANTIBODIES - CHROMATIN-ASSOCIATED PROTEINS
For transcription factors, chromatin reader proteins, remodelers, and more -
validated directly in CUT&RUN
View
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SNAP-CHIP® SPIKE-IN CONTROLS
Defined spike-in controls for improved ChIP-seq workflows
View
DCYPHER™ NUCLEOSOME PANELS
Our diverse nucleosome library in a convenient, ready-to-screen 96 well plate
format
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EPIDYNE® CHROMATIN REMODELING SUBSTRATES
Nucleosomes specifically designed to study chromatin remodeling enzymes
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NUCLEOSOMES COMPLETE LIST
Need a nucleosome? We have it covered.
View
RECOMBINANT NUCLEOSOMES (RNUCS)
Unmodified nucleosomes, with and without histone tails
View
MODIFIED DESIGNER NUCLEOSOMES (DNUCS™)
Contain distinct histone post-translational modifications, or PTMs
View
SNAP-CUTANA™ SPIKE-IN CONTROLS
Essential controls for CUTANA CUT&RUN and CUT&Tag epigenomic assays
View
SNAP-CHIP® SPIKE-IN CONTROLS
Defined spike-in controls for improved ChIP-seq workflows
View
DCYPHER™ NUCLEOSOME PANELS
Our diverse nucleosome library in a convenient, ready-to-screen 96 well plate
format
View
EPIDYNE® CHROMATIN REMODELING SUBSTRATES
Nucleosomes specifically designed to study chromatin remodeling enzymes
View
NUCLEOSOMES COMPLETE LIST
Need a nucleosome? We have it covered.
View
RECOMBINANT NUCLEOSOMES (RNUCS)
Unmodified nucleosomes, with and without histone tails
View
MODIFIED DESIGNER NUCLEOSOMES (DNUCS™)
Contain distinct histone post-translational modifications, or PTMs
View
Previous
Next
EPIDYNE® CHROMATIN REMODELING ENZYMES
Highly pure chromatin remodeling enzymes, including SMARCA2/BRM and SMARCA4/BRG1
View
HISTONE BINDING DOMAINS
A diverse collection of chromatin binding domains, including bromodomains and
YEATS domains
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IDEA TOOLBOX
Toolbox for Innovation and Discovery of Epigenetic Applications offers early
access our newest products
View
PAG-MNASE
Crucial enzyme for CUT&RUN chromatin mapping experiments
View
PAG-TN5
Enables antibody-directed tagmentation in CUT&Tag assays
View
EPIDYNE® CHROMATIN REMODELING ENZYMES
Highly pure chromatin remodeling enzymes, including SMARCA2/BRM and SMARCA4/BRG1
View
HISTONE BINDING DOMAINS
A diverse collection of chromatin binding domains, including bromodomains and
YEATS domains
View
IDEA TOOLBOX
Toolbox for Innovation and Discovery of Epigenetic Applications offers early
access our newest products
View
PAG-MNASE
Crucial enzyme for CUT&RUN chromatin mapping experiments
View
PAG-TN5
Enables antibody-directed tagmentation in CUT&Tag assays
View
EPIDYNE® CHROMATIN REMODELING ENZYMES
Highly pure chromatin remodeling enzymes, including SMARCA2/BRM and SMARCA4/BRG1
View
Previous
Next
SERVICES
CUTANA™ CUT&RUN SERVICES
EpiCypher’s CUTANA™ CUT&RUN Services provide unique access to our genomic
expertise, enabling diverse applications across biomedical research and drug
development.
Learn More
EPIDYNE® CHROMATIN REMODELING HTS ASSAYS
EpiDyne® enables direct detection of chromatin remodeling activity, and is ideal
for HTS and inhibitor profiling. EpiDyne services accelerate assay development
and generate robust results.
Learn More
DCYPHER™ ASSAY SERVICES FOR NOVEL CHROMATIN INTERACTIONS
dCypher™ assay services rapidly interrogate chromatin reader binding against a
collection of modified histone peptides or nucleosomes, revealing novel
mechanisms in chromatin biology.
Learn More
CUSTOM NUCLEOSOME DEVELOPMENT
Nucleosomes are the preferred target of chromatin interacting proteins, and are
optimal substrates for epigenetics research. To address this need, EpiCypher
provides custom nucleosome development.
Learn More
OUR THOUGHTS
Check in for the latest in EpiCypher technology, chromatin research, and
conference news!
11th Jan 2024 Christine M. Brady
FIVE EPIGENETIC CONFERENCES TO ADD TO YOUR 2024 CALENDAR
Porto, Portugal. Photo by Nick Karvounis on Unsplash. Scientific conferences
provide a great...
Read More
20th Dec 2023 Ellen N. Weinzapfel, PhD
TOP CUT&RUN AND CUT&TAG CHROMATIN MAPPING PAPERS OF 2023
2023 was a remarkable year for science. The first CRISPR-based gene therapy was
approved...
Read More
21st Sep 2023 Ellen Weinzpafel, PhD
HAVE CUT&RUN QUESTIONS? INTRODUCING OUR TECH SUPPORT CENTER
In the ever-evolving landscape of molecular biology, the quest to unravel the
intr...
Read More
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