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DATING GIRLS NUMBER IN PHNOM PENH CAMBODIA

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full sequence of Msb is bp in length and showed a bp conserved region between
Xiphophorus and Poecilia. BLAST search performed on this sequence revealed no
significant similarities. However the exact gene expression event of Msb is
still unknown and requires further investigation. Association of rs and rs
single-nucleotide polymorphisms with susceptibility to ankylosing spondylitis in
east Asian population: a meta-analysis.

Several studies have been conducted in east Asian population to evaluate the
association between rs and rs single-nucleotide polymorphisms SNPs with
susceptibility to ankylosing spondylitis AS , but the outcomes are in
consistent.

A summary evaluation of the evidence supporting the associations has not been
performed. Therefore, we performed this meta-analysis to access whether the two
SNPs are related to ankylosing spondylitis. Four papers including five studies
were obtained for this meta-analysis. Based on a comprehensive analysis of the
currently available evidence, rs SNP is not significantly associated with the
predisposition of AS, while rs SNP is likely a susceptibility variant for AS in
east Asianpopulation.

Further studies with different population groups are needed to confirm these
potential associations. Genetic variations in influx transporter gene SLC22A1
are associated with clinical responses to imatinib mesylate among Malaysian
chronic myeloid leukaemia patients. Imatinib mesylate IM , a well-established
gold standard drug in the treatment of chronic myeloid leukaemia CML , is a
synthetic tyrosine kinase inhibitor. Despite excellent efficacy, a significant
number of patients on IM therapy develop resistance to IM. Currently, great
focus has been laid on the effect of interindividual pharmacogenetic variability
on IM treatment responses.

On evaluating the association of genotypes with risk of IM resistance
development, heterozygous CG and homozygous GG variant genotypes showed
significantly higher risk for developing resistance to IM treatment with odds
ratio OR : 1. For exon 7, AA carriers together with the presence of both the
8-bp insertion and 3-bp deletion, and Mdel alleles showed higher possibility of
developing resistance towards IMtreatment.

For the IL-2 gene, two alleles of A and G were also detected using the Mnl I
restriction enzyme with the frequencies of 0. Further, in a mean comparison
analysis, there were also significant differences between different genotypes of
the IL-2 gene in average EWat 28 and 30 weeks of age, in which AG genotypes
showed higher performance. Therefore, it can be concluded that the
above-mentioned polymorphisms could be considered as the pivotal geneticmakers
to improveMazandaran native fowl breeding programmes to achieve the optimum
performance in productive traits more efficiently.

Gene expression profiling of coronary artery disease and its relation with
different severities. Global gene expression profiling is a powerful tool
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expressed genes DEGs ; their biological processes for coronary artery disease
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The weight of different severities of lesion was estimated using a modified
Gensini score. The gene expression profiling was performed using the Affymetrix
microarray platform. Functionally annotated genes were found in an unique set
and could be distinguishing two distinct severities of CAD. The biological
processes such ascellular migration, locomotion, cell adhesion, cytokine
production, positive regulation of cell death etc.

The 61 DEGs were identified, those have changes their expression with different
severities of atherosclerotic lesions, in which 13 genes had more than two-fold
change in expression between SVD and TVD. The consistent findings were obtained
on validation of microarray gene expression of selected 10 genes in a separate
cohort using real-time PCR.

This study identified putative candidategenes and their biological processes
predisposing toward and affecting the severity of CAD. Sox4 , a member of the
SoxC subfamily which of the Sox family, plays important roles in the development
of the vertebrate gonad and nervous system. We have cloned a Sox4 homologue from
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sequence analysis showed that MaSox4 is anonsecretory hydrophilic protein.
Quantitative real-time reverse transcription polymerase chain reaction and in
situ hybridization assay revealed that MaSox4 was ubiquitously expressed during
embryogenesis and is present in various adult tissues, especially in the central
nervous system. Detection of c. The aim of this study was to identify the gene
causing bilateral autosomal dominant zonular congenital cataract ADZCC without
pulverulent opacities in an extended Muslim family by exome sequencing and
subsequent analysis.

An extended family of 37 members 14 affected and 23 unaffected who belong to
different nuclear families was screened for causative gene. Review of exome
sequencing data of the proband and her unaffected son for 40 known genes causing
congenital nonsyndromic cataracts revealed two variants, namely c. Further,
validation of these two variants in the entire family showed cosegregation of c.
Variation of c. The mutation c. Thus, the mutation c.

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