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CDI Labs LogoCDI Labs Company Logo * Products * HuProt™ Human Microarray * VirScan™ Viral PhIP-Seq* * HuScan® Human PhIP-Seq* * MouseScan™ Murine PhIP-Seq* * VirD™ Membrane Protein * * These products are provided exclusively by CDI Labs Canada. * Services * HuProt™ Microarray * VirScan™ Viral PhIP-Seq* * HuScan® Human PhIP-Seq* * MouseScan™ Murine PhIP-Seq* * VirD™ Membrane Protein Array * Antibody Development & Manufacturing * * These services are provided exclusively by CDI Labs Canada. * Autoantibody Seromics * Overview * Autoimmune Diseases * Immuno-oncology * Neurological Diseases * Infectious Diseases * Genetic Diseases * Resources * Resources * Library Content * Publications * Videos * News & Events * Events * News * Company * About Us * Leadership * Meet CDI Labs * Contact Us * Privacy Policy * CONTACT US You are now leaving the CDI Labs U.S. website and will be directed to the CDI Labs Canada website. GO Cancel CDI LABS Watermark LogoCDI LABS Company Watermark Logo Image The world’s most comprehensive content to power THE AUTOANTIBODY SEROMICS REVOLUTION With over 21,000 full-length human proteins, the HuProt™ microarray is the world's largest and most comprehensive collection of thoroughly validated proteins. HUPROT MICROARRAY CDI LABS Watermark LogoCDI LABS Company Watermark Logo Image Our Industry-leading HuProt™ microarray contains >21,000 GST-PURIFIED FULL-LENGTH PROTEINS HuProt is quality confirmed with anti-GST QA/QC. Successful folding has been demonstrated by kinase autophosphorylation assay. HUPROT MICROARRAY CDI LABS Watermark LogoCDI LABS Company Watermark Logo Image HuScan® - Human PhIP-Seq Antibody Profiling Services EPITOPE-LEVEL ANTIBODY DISCOVERY Human proteome epitope-level autoantibody profiling service via T7 phage display and immunoprecipitation sequencing (PhIP-Seq). HUSCAN PHIP-SEQ CDI LABS Watermark LogoCDI LABS Company Watermark Logo Image CDI Labs Autoantibody Profiling Services HIGH-THROUGHPUT AUTOANTIBODY SIGNATURE VALIDATION CDI Labs offers high-throughput focused array services to validate autoantibody signatures discovered with the HuProt Microarray. HUPROT SERVICES CDI LABS NEWS | * Apr 2, 2024Webinar: Discovering Biomarkers, Cross-Reacting Antibodies, and More... * Aug 2, 2023Press Release: Barney E. Saunders Ph.D. has been appointed Chief Executive Officer of CDI Laboratories * Jan 9, 2023Press Release: BroadOak Capital Partners Invests in CDI Laboratories to Expand and Scale Antibody Biomarker... * Sep 23, 2020Press Release: CDI Labs HuProt™ Protein Arrays Instrumental in Recent Study of Multisystem Inflammatory... * Feb 4, 2020Press Release: CDI Labs Launches Two New Powerful Assays to its Biomarker Discovery Platform all news THE WORLD'S MOST COMPREHENSIVE PORTFOLIO FOR AUTOANTIBODY DETECTION TRANSFORMATIONAL PRODUCTS AND SERVICES FOR PROTEOME-WIDE AUTOANTIBODY PROFILING, BIOMARKER DISCOVERY, CROSS-REACTIVITY SCREENING, AND OTHER WHOLE-PROTEOME TARGET IDENTIFICATION AND INTERACTION ASSAYS WE OFFER THE MOST POWERFUL ANTIGEN LIBRARIES MORE INFO >21,000 FULL-LENGTH PROTEINS GST-purified validated full-length recombinant proteins MORE INFO CELL MEMBRANE-EMBEDDED Purified virion display correctly-folded membrane-embedded GPCRs MORE INFO MOST VERTEBRATE VIRAL PROTEOMES Detects antibodies against >68,000 vertebrate viral protein sequences MORE INFO ALL HUMAN PROTEOME Detects antibodies against 48,921 unique human proteins and protein isoforms MORE INFO ALL MURINE PROTEOME Detects antibodies against 50,135 unique murine proteins and protein isoforms CDI Labs CanadaCanada FlagHuScan, MouseScan and VirScan are provided exclusively by CDI Labs Canada. CDI LABS AUTOANTIBODY SEROMICS The serome is the total secreted antibody repertoire of a single individual; each serome is unique and created by a person's lifetime of adaptive immune experiences. The goal of the emerging scientific field of 'autoantibody seromics' is to understand the largest impacts of the serome on human health, disease, and clinical outcomes. MORE CONTENT AND BETTER DATA We start with sequence-confirmed plasmids, then individually express and GST-purify proteins from S. cerevisiae. Piezolelectric printing is used to spot these in duplicate alongside controls. Quality is confirmed with anti-GST QA/QC. Successful folding demonstrated by kinase autophosphorylation assay. PUBLICATIONS 200+PEER-REVIEWED PUBLICATIONS With over 200 publications (and growing), our antibody seromics solutions and HuProt array continue to play a key role in life sciences by contributing to critical studies that help accelerate research, advance discoveries, and translate discoveries to novel products that improve human health. Learn More CUSTOMER-BASE 190+CUSTOMER BASE Our customer base continues to expand throughout North America, Europe, and Asia Pacific, and is a testament to the quality and consistency of our products and services. Contact Us FOUNDERS BOEKE, ZHU & BLACKSHAWAT JOHNS HOPKINS UNIVERSITY Funded by NIH Common Fund Support for the Development of Protein Capture Reagents and Technologies, the HuProt Protein Microarray was created by CDI Labs co-founders Jef Boeke, Heng Zhu, Dan Eichinger, and Seth Blackshaw, faculty members at the High Throughput Biology (HIT) Center at the Johns Hopkins University School of Medicine. Learn More DATA AND TECHNOLOGY VALIDATED BY SCIENTISTS "WE ELECTED TO USE THE HUPROT MICROARRAY BECAUSE IT IS AN EXTENSIVE PLATFORM THAT CONTAINS OVER 21,000 UNIQUE, INDIVIDUALLY PURIFIED FULL-LENGTH HUMAN PROTEINS AND PROTEIN ISOFORMS IN DUPLICATE, COVERING MORE THAN 81% OF THE PROTEOME." OncologistSchool of Medicine Research (as mentioned in "Baseline Serum Autoantibody Signatures Predict Recurrence and Toxicity in Melanoma Patients Receiving Adjuvant Immune Checkpoint Blockade" - AACR Clinical Caner Research - September 2022) DATA AND TECHNOLOGY VALIDATED BY SCIENTISTS "THIS (VIRSCAN) ASSAY, WHICH USES PHAGE DISPLAY IMMUNOPRECIPITATION AND SEQUENCING, IS A SENSITIVE AND FOCUSED HIGH-COMPREHENSIVE APPROACH THAT ENABLES THOROUGH SEROLOGICAL PROFILING OF ANTIVIRAL ANTIBODIES IN HUMANS AND, CONSEQUENTLY, THE IDENTIFICATION OF VIRAL EXPOSURE THROUGHOUT THE HUMAN VIROME." Faculty of MedicineResearch Institution (as mentioned in "Human virome profiling identified CMV as the major viral driver of a high accumulation of senescent CD8+ T cells in patients with advanced NSCLC" - Science Advances - November 2023) DATA AND TECHNOLOGY VALIDATED BY SCIENTISTS "BY USING (HUPROT) PROTEIN ARRAYS, WE WERE ABLE TO EVALUATE A BROADER RANGE OF ANTIGENS COMPARED TO PREVIOUS INVESTIGATIONS." Senior ScientistBiotech Research (poster presentation at the San Antonio Breast Cancer Symposium 2023) ASK ABOUT OUR SEROMICS PRODUCTS AND SERVICES * REQUIRED Personal Info First Name* Last Name* Work Email Address* Phone Zip Code* Work Info Company Name* Job Title* Country* Estimated Sample Number Platform of Interest Info PLATFORM OF INTEREST* HuProt™ Proteome Microarray VirScan™ PhIP-Seq* HuScan® PhIP-Seq* MouseScan™ PhIP-Seq* VirD™ Membrane Arrays Antibody Development & Manufacturing Other * This service is provided exclusively by CDI Labs Canada. How did you hear about us?* Select One Referral Web search Google search ad Publication Social media CDI Labs email Event / meeting Other Select One Referral Web search Google search ad Publication Social media CDI Labs email Event / meeting Other Assay Goal, Inquiry and Subscribe Option Assay Goal Assay Goal (select one) Seromics (antibody responses and biomarkers) TargetID (determine binding target or specificity) Other Assay Goal (select one) Seromics (antibody responses and biomarkers) TargetID (determine binding target or specificity) Other Questions / Requests I would like to receive the latest news and updates from CDI Labs. By clicking submit, you consent to allow CDI Labs to store and process the personal information submitted in order to provide you the content requested. Please refer to CDI Labs Privacy Policy. FEATURED PUBLICATION View all publications * Mar 19 * | * 2018 HUPROT: A TOOLBOX OF IMMUNOPRECIPITATION-GRADE MONOCLONAL ANTIBODIES TO HUMAN TRANSCRIPTION FACTORS Anand Venkataraman, Blackshaw Seth, et. al. ON NATURE METHODS * VIEW ON JOURNAL * Feb 22 * | * 2023 HUPROT: AUTOIMMUNITY IN DOWN’S SYNDROME VIA CYTOKINES, CD4 T CELLS AND CD11C+ B CELLS Louise Malle, Dusan Bogunovic, et. al. ON NATURE * * VIEW ON JOURNAL * Sep 15 * | * 2022 HUPROT: BASELINE SERUM AUTOANTIBODY SIGNATURES PREDICT RECURRENCE AND TOXICITY IN MELANOMA PATIENTS RECEIVING ADJUVANT IMMUNE CHECKPOINT BLOCKADE Paul Johannet, Iman Osman, et. al. ON AACR - CLINICAL CANCER RESEARCH * * VIEW ON JOURNAL * Nov 8 * | * 2023 VIRSCAN: HUMAN VIROME PROFILING IDENTIFIED CMV AS THE MAJOR VIRAL DRIVER OF A HIGH ACCUMULATION OF SENESCENT CD8+ T CELLS IN PATIENTS WITH ADVANCED NSCLC Marie Naigeon, Nathalie Chaput, et. al. ON SCIENCE ADVANCES * VIEW ON JOURNAL * Nov 8 * | * 2023 HUPROT: AUTOANTIBODIES AGAINST TYPE I IFNS IN HUMANS WITH ALTERNATIVE NF-ΚB PATHWAY DEFICIENCY Tom Le Voyer, Anne Puel, et. al. ON NATURE * * VIEW ON JOURNAL * Apr 13 * | * 2022 HUPROT: TEMPORAL REPRODUCIBILITY OF IGG AND IGM AUTOANTIBODIES IN SERUM FROM HEALTHY WOMEN T. V. Clendenen, Y. Chen, et. al. ON NATURE SCIENTIFIC REPORTS * * VIEW ON JOURNAL * Feb 3 * | * 2021 HUPROT: IGA TRANSCYTOSIS AND ANTIGEN RECOGNITION GOVERN OVARIAN CANCER IMMUNITY Subir Biswas, Jose R. Conejo-Garcia, et. al. ON NATURE * * VIEW ON JOURNAL NEWS View all news * Aug 2 * | * 2023 Press Release BARNEY E. SAUNDERS PH.D. HAS BEEN APPOINTED CHIEF EXECUTIVE OFFICER OF CDI LABORATORIES Read More * Jan 9 * | * 2023 Press Release BROADOAK CAPITAL PARTNERS INVESTS IN CDI LABORATORIES TO EXPAND AND SCALE ANTIBODY BIOMARKER DISCOVERY PLATFORMS Read More * Sep 23 * | * 2020 Press Release CDI LABS HUPROT™ PROTEIN ARRAYS INSTRUMENTAL IN RECENT STUDY OF MULTISYSTEM INFLAMMATORY SYNDROME IN CHILDREN (MIS-C) Read More * Feb 4 * | * 2020 Press Release CDI LABS LAUNCHES TWO NEW POWERFUL ASSAYS TO ITS BIOMARKER DISCOVERY PLATFORM Read More * Mar 6 * | * 2019 Press Release CDI LABS TO SHOWCASE IMMUNO-ONCOLOGY PRODUCTS & SERVICES AT AACR 2019 Read More * Mar 5 * | * 2019 Press Release CDI LABS RELEASES HUPROT™ V4.0 - ADDING ADDITIONAL CONTENT TO LARGEST CONTENT HUMAN PROTEOME MICROARRAY IN THE WORLD Read More * Apr 19 * | * 2018 News CDI LABORATORIES INC. OPENS $17M BIOTECH LAB IN MAYAGÜEZ Read More * Mar 28 * | * 2018 Press Release CDI LABS' MONOCLONAL ANTIBODY DEVELOPMENT PIPELINE FEATURED IN NATURE METHODS Read More * Mar 8 * | * 2018 Press Release CDI LABS COLLABORATES ON DISCOVERY OF NEW BIOMARKERS FOR ZIKA INFECTION Read More * Nov 28 * | * 2017 Press Release CDI LABS CITES NEW RESEARCH IDENTIFYING EARLY LUNG CANCER AUTOANTIBODY BIOMARKERS USING HUPROT™ Read More * Nov 1 * | * 2017 News THE WORLD'S LARGEST HUMAN PROTEOME MICROARRAY: ADVANCING PROTEIN BIOMARKER DISCOVERY Read More * May 25 * | * 2017 Press Release CDI LABS EXPANDS HUPROT™ - THE HIGHEST CONTENT HUMAN PROTEOME MICROARRAY IN THE WORLD Read More * Apr 17 * | * 2017 Press Release CDI LABORATORIES AND NEOBIOTECHNOLOGIES FORM ALLIANCE TO DISTRIBUTE CDI'S 2500 MONOSPECIFIC TRANSCRIPTION FACTOR ANTIBODIES Read More EVENTS Join us at these upcoming events CDI Labs will be attending. View all events WEBINAR * Apr 2 * - * Apr 2 * GenomeWeb DISCOVERING BIOMARKERS, CROSS-REACTING ANTIBODIES, AND MORE... ONLINE More Info CONFERENCE * Apr 5 * - * Apr 10 * San Diego AACR 2024 BOOTH 4145 More Info CONFERENCE * May 3 * - * May 7 * Chicago IMMUNOLOGY2024 BOOTH 532 More Info CONFERENCE * Jun 18 * - * Jun 21 * San Francisco FOCIS 2024 BOOTH CDI LABS More Info CDI Labs Footer LogoCDI Labs Company Footer Logo BECOME PART OF THE CDI LABS COMMUNITY Sign up to receive emails on our latest news and updates. Your First Name First Name Your Last Name Last Name Your Work Email Work Email Please enter ONLY your work email address. Sign Up Submit Button PRODUCTS & SERVICES * HuProt™ Proteome Microarray * VirScan™ Viral PhIP-Seq* * HuScan® Human PhIP-Seq* * MouseScan™ Murine PhIP-Seq* * VirD™ Membrane Protein Array * Antibody Development * Autoantibody Seromics Overview * * These products and services are provided exclusively by CDI Labs Canada. 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