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Submitted URL: https://whales-market.pw/#ne
Effective URL: https://whales-market.pw/
Submission Tags: 0xscam
Submission: On April 09 via api from US — Scanned from NL
Effective URL: https://whales-market.pw/
Submission Tags: 0xscam
Submission: On April 09 via api from US — Scanned from NL
Form analysis 1 forms found in the DOM
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<div class="aem-container " id="">
<div class="container-child ">
<div class="cmp-link" data-testid="cmp-button">
<a href="/patient-centered-care" class="cmp-anchor--plain cmp-button cmp-button__link " id="button-0cdef1615a" data-cmp-data-layer="{" target":"patient-centered="" care","category":"global-header","action":"expanded|care="" at="" mayo="" clinic"}"=""><span aria-hidden="false" class="cmp-button__inner cmp-button__inner--width-full cmp-button__inner--type-text cmp-button__inner--focus-primary "><span class="cmp-button__inner-wrapper"><span class="cmp-button__inner-main"><span role="text" class="cmp-button__text"> <!-- -->Patient-Centered Care</span></span><span class="cmp-icon icon__chevron-right cmp-icon--size-16"><svg data-name="32x32-Guides" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 16 16"><path d="M5.707 13.707L4.293 12.293 8.586 8 4.293 3.707 5.707 2.293 11.414 8 5.707 13.707z"></path></svg></span></span></span></a>
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<div class="cmp-link" data-testid="cmp-button">
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<div class="aem-container " id="">
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<div class="cmp-link" data-testid="cmp-button">
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<div class="aem-container aem-Grid aem-Grid--12 aem-Grid--default--12 aem-Grid--mayo_x-large--6 aem-Grid--mayo_x-small--11 aem-Grid--mayo_small--11 " id="">
<div class="aem-GridColumn aem-GridColumn--default--12 aem-GridColumn--mayo_x-large--6 aem-GridColumn--mayo_x-small--11 aem-GridColumn--mayo_small--11 aem-GridColumn">
<div><!-- googleoff: all --></div>
<ul class="cmp-list__container cmp-list--navigation cmp-list--inline-spacing-0x " id="header__content-right" data-testid="cmp-list">
<li class="cmp-list__item aem-GridColumn--mayo_x-small--hide aem-GridColumn--mayo_small--hide">
<div class="cmp-link" data-testid="cmp-button">
<a href="/appointments" class="cmp-anchor--plain cmp-button cmp-button__link " id="button-be649aa4dd" data-cmp-data-layer="{" target":"request="" appointment","category":"global-header","action":"top_header"}"=""><span aria-hidden="false" class="cmp-button__inner cmp-button__inner--width-full cmp-button__inner--type-navigation cmp-button__inner--focus-primary "><span class="cmp-button__inner-wrapper"><span class="cmp-button__inner-main"><span role="text" class="cmp-button__text"> <!-- -->Request appointment</span></span><span class="cmp-icon icon__chevron-right cmp-icon--size-16"><svg data-name="32x32-Guides" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 16 16"><path d="M5.707 13.707L4.293 12.293 8.586 8 4.293 3.707 5.707 2.293 11.414 8 5.707 13.707z"></path></svg></span></span></span></a>
</div>
</li>
<li class="cmp-list__item ">
<div class="cmp-link" data-testid="cmp-button">
<a href="https://onlineservices.mayoclinic.org/content/staticpatient/showpage/patientonline" class="cmp-anchor--plain cmp-button cmp-button__link " id="button-e80e35ed41" data-cmp-data-layer="{" target":"log="" in","category":"global-header","action":"top_header"}"=""><span aria-hidden="false" class="cmp-button__inner cmp-button__inner--width-full cmp-button__inner--type-navigation cmp-button__inner--focus-primary "><span class="cmp-button__inner-wrapper"><span class="cmp-button__inner-main"><span class="cmp-icon icon__user left-aligned cmp-icon--size-24"><svg data-name="Layer 1" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 24 24" focusable="false" aria-hidden="true"><path d="M21,22H19V19.2002A3.28861,3.28861,0,0,0,15.63623,16H8.36377A3.28861,3.28861,0,0,0,5,19.2002V22H3V19.2002A5.29005,5.29005,0,0,1,8.36377,14h7.27246A5.29005,5.29005,0,0,1,21,19.2002Z"></path><path d="M12,12a5,5,0,1,1,5-5A5.00588,5.00588,0,0,1,12,12Zm0-8a3,3,0,1,0,3,3A3.00328,3.00328,0,0,0,12,4Z"></path></svg></span><span role="text" class="cmp-button__text"> <!-- -->Log in</span></span><span class="cmp-icon icon__chevron-right cmp-icon--size-16"><svg data-name="32x32-Guides" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 16 16"><path d="M5.707 13.707L4.293 12.293 8.586 8 4.293 3.707 5.707 2.293 11.414 8 5.707 13.707z"></path></svg></span></span></span></a>
</div>
</li>
<li class="cmp-list__item ">
<div><!-- googleoff: all --></div>
<div class="cmp-search-button "><button aria-expanded="false" data-cmp-data-layer="{" category":"global-header","action":"initial_state","target":"search"}"="" type="button" data-testid="cmp-button"
class="cmp-button cmp-button__button "><span class="cmp-search-button__innerButton"><span class="cmp-icon icon__search cmp-icon--size-24"><svg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 24 24"
focusable="false" aria-hidden="true">
<path d="M10,2a8,8,0,1,0,8,8A8.00917,8.00917,0,0,0,10,2ZM4,10a6,6,0,1,1,6,6A6.00657,6.00657,0,0,1,4,10Z"></path>
<path d="M21.707,20.293,17.73816,16.3241a10.08573,10.08573,0,0,1-1.41406,1.41406L20.293,21.707A.99989.99989,0,0,0,21.707,20.293Z"></path>
</svg><span class="sr-only">Search</span></span></span></button></div>
<div><!-- googleon: all --></div>
</li>
<li class="cmp-list__item aem-GridColumn--mayo_x-large--hide">
<div data-panelcontainer="hamburger" data-testid="cmp-hamburger" class="cmp-hamburger "><button aria-expanded="false" type="button" data-testid="cmp-button"
class="cmp-button cmp-button__button cmp-hamburger__button"><span class="cmp-hamburger__inner-button"><span class="cmp-icon icon__menu cmp-icon--size-24"><svg xmlns="http://www.w3.org/2000/svg"
viewBox="0 0 24 24" focusable="false" aria-hidden="true">
<path d="M21 7H3V5H21V7Z" fill="#080808"></path>
<path d="M21 13H3V11H21V13Z" fill="#080808"></path>
<path d="M3 19H21V17H3V19Z" fill="#080808"></path>
</svg><span class="sr-only">Menu</span></span></span></button>
<div class="cmp-hamburger__content">
<div data-cmp-hook-hamburger="item" data-cmp-expanded="true">
<div><!-- googleoff: all --></div>
<div class="aem-container " id="">
<div class="container-child ">
<div><!-- googleoff: all --></div>
<div class="aem-container " id="">
<div class="container-child aem-GridColumn--mayo_medium--hide aem-GridColumn--mayo_large--hide">
<div><!-- googleoff: all --></div>
<div class="aem-container cmp-container--column-padding-0x " id="header__hamburger-mobile-buttons-container">
<div class="container-child aem-GridColumn--mayo_x-small--none aem-GridColumn--mayo_small--none">
<div class="cmp-link" data-testid="cmp-button">
<a href="/appointments" class="cmp-anchor--plain cmp-button cmp-button__link cmp-button__button--width-full" id="button-fe79ff8297" data-cmp-data-layer="{" target":"request="" appointment","category":"global-header","action":"landing_state"}"=""><span aria-hidden="false" class="cmp-button__inner cmp-button__inner--width-full cmp-button__inner--type-mobile-navigation-cta cmp-button__inner--color-primary "><span class="cmp-button__inner-wrapper"><span class="cmp-button__inner-main"><mc-icon icon-name="calendar-date-range" icon-size="medium" class="cmp-icon icon_calendar-date-range left-aligned hydrated"></mc-icon><span role="text" class="cmp-button__text"> <!-- -->Request appointment</span></span><span class="cmp-icon icon__chevron-right cmp-icon--size-16"><svg data-name="32x32-Guides" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 16 16"><path d="M5.707 13.707L4.293 12.293 8.586 8 4.293 3.707 5.707 2.293 11.414 8 5.707 13.707z"></path></svg></span></span></span></a>
</div>
</div>
<div class="container-child aem-GridColumn--mayo_x-small--none aem-GridColumn--mayo_small--none">
<div class="cmp-link" data-testid="cmp-button">
<a href="https://philanthropy.mayoclinic.org/donateMC" class="cmp-anchor--plain cmp-button cmp-button__link cmp-button__button--width-full" id="button-34f6db6296" data-cmp-data-layer="{" target":"donate","category":"global-header","action":"landing_state"}"=""><span aria-hidden="false" class="cmp-button__inner cmp-button__inner--width-full cmp-button__inner--type-mobile-navigation-cta cmp-button__inner--color-primary "><span class="cmp-button__inner-wrapper"><span class="cmp-button__inner-main"><mc-icon icon-name="giving-charity" icon-size="medium" class="cmp-icon icon_giving-charity left-aligned hydrated"></mc-icon><span role="text" class="cmp-button__text"> <!-- -->Donate</span></span><span class="cmp-icon icon__chevron-right cmp-icon--size-16"><svg data-name="32x32-Guides" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 16 16"><path d="M5.707 13.707L4.293 12.293 8.586 8 4.293 3.707 5.707 2.293 11.414 8 5.707 13.707z"></path></svg></span></span></span></a>
</div>
</div>
<div class="container-child aem-GridColumn--mayo_x-small--none aem-GridColumn--mayo_small--none">
<div class="cmp-link" data-testid="cmp-button">
<a href="/diseases-conditions" class="cmp-anchor--plain cmp-button cmp-button__link cmp-button__button--width-full" id="button-6091e014d5" data-cmp-data-layer="{" target":"diseases="" &="" conditions","category":"global-header","action":"landing_state"}"=""><span aria-hidden="false" class="cmp-button__inner cmp-button__inner--width-full cmp-button__inner--type-mobile-navigation-cta cmp-button__inner--color-primary "><span class="cmp-button__inner-wrapper"><span class="cmp-button__inner-main"><mc-icon icon-name="bacteria" icon-size="medium" class="cmp-icon icon_bacteria left-aligned hydrated"></mc-icon><span role="text" class="cmp-button__text"> <!-- -->Diseases & conditions</span></span><span class="cmp-icon icon__chevron-right cmp-icon--size-16"><svg data-name="32x32-Guides" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 16 16"><path d="M5.707 13.707L4.293 12.293 8.586 8 4.293 3.707 5.707 2.293 11.414 8 5.707 13.707z"></path></svg></span></span></span></a>
</div>
</div>
<div class="container-child aem-GridColumn--mayo_x-small--none aem-GridColumn--mayo_small--none">
<div class="cmp-link" data-testid="cmp-button">
<a href="/appointments/find-a-doctor" class="cmp-anchor--plain cmp-button cmp-button__link cmp-button__button--width-full" id="button-b1413f780c" data-cmp-data-layer="{" target":"find="" a="" doctor","category":"global-header","action":"landing_state"}"=""><span aria-hidden="false" class="cmp-button__inner cmp-button__inner--width-full cmp-button__inner--type-mobile-navigation-cta cmp-button__inner--color-primary "><span class="cmp-button__inner-wrapper"><span class="cmp-button__inner-main"><mc-icon icon-name="stethoscope" icon-size="medium" class="cmp-icon icon_stethoscope left-aligned hydrated"></mc-icon><span role="text" class="cmp-button__text"> <!-- -->Find a doctor</span></span><span class="cmp-icon icon__chevron-right cmp-icon--size-16"><svg data-name="32x32-Guides" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 16 16"><path d="M5.707 13.707L4.293 12.293 8.586 8 4.293 3.707 5.707 2.293 11.414 8 5.707 13.707z"></path></svg></span></span></span></a>
</div>
</div>
</div>
<div><!-- googleon: all --></div>
</div>
<div class="container-child aem-GridColumn--mayo_x-large--hide">
<div class="cmp-accordion cmp-accordion--mobile-main-navigation " data-panelcontainer="accordion" data-testid="cmp-accordion">
<div data-cmp-hook-accordion="item" data-cmp-expanded="false" class="cmp-accordion__item">
<div class="cmp-accordion__title-grid"><button aria-expanded="false" aria-controls="accordion-c23f922fa3-0" type="button" data-testid="cmp-button"
class="cmp-button cmp-button__button cmp-accordion__title-column cmp-accordion__button"><span class="cmp-accordion__button-inner"><span class="cmp-accordion__button-title">Care at Mayo
Clinic</span><span class="cmp-accordion__button-icon"><span class="cmp-icon icon__chevron-down cmp-icon--size-16"><svg data-name="32x32-Guides" xmlns="http://www.w3.org/2000/svg"
viewBox="0 0 16 16">
<path d="M8 11.414L2.293 5.707 3.707 4.293 8 8.586 12.293 4.293 13.707 5.707 8 11.414z"></path>
</svg></span></span></span></button></div>
<div id="accordion-c23f922fa3-0" data-cmp-hook-accordion="panel" class="cmp-accordion__item-content">
<div><!-- googleoff: all --></div>
<div class="aem-container " id="">
<div class="container-child aem-GridColumn--mayo_large--none aem-GridColumn--mayo_medium--none">
<div><!-- googleoff: all --></div>
<div class="aem-container " id="">
<div class="container-child ">
<div class="cmp-link" data-testid="cmp-button">
<a href="/patient-centered-care" class="cmp-anchor--plain cmp-button cmp-button__link " id="button-941206d5b9" data-cmp-data-layer="{" target":"patient-centered="" care","category":"global-header","action":"expanded|care="" at="" mayo="" clinic"}"=""><span aria-hidden="false" class="cmp-button__inner cmp-button__inner--width-full cmp-button__inner--type-text cmp-button__inner--focus-primary "><span class="cmp-button__inner-wrapper"><span class="cmp-button__inner-main"><span role="text" class="cmp-button__text"> <!-- -->Patient-Centered Care</span></span><span class="cmp-icon icon__chevron-right cmp-icon--size-16"><svg data-name="32x32-Guides" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 16 16"><path d="M5.707 13.707L4.293 12.293 8.586 8 4.293 3.707 5.707 2.293 11.414 8 5.707 13.707z"></path></svg></span></span></span></a>
</div>
</div>
<div class="container-child aem-GridColumn--mayo_medium--none aem-GridColumn--mayo_large--none">
<div class="cmp-link" data-testid="cmp-button">
<a href="/about-mayo-clinic" class="cmp-anchor--plain cmp-button cmp-button__link " id="button-f5a5e388d3" data-cmp-data-layer="{" target":"about="" mayo="" clinic","category":"global-header","action":"expanded|care="" at="" clinic"}"=""><span aria-hidden="false" class="cmp-button__inner cmp-button__inner--width-full cmp-button__inner--type-text cmp-button__inner--focus-primary "><span class="cmp-button__inner-wrapper"><span class="cmp-button__inner-main"><span role="text" class="cmp-button__text"> <!-- -->About Mayo Clinic</span></span><span class="cmp-icon icon__chevron-right cmp-icon--size-16"><svg data-name="32x32-Guides" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 16 16"><path d="M5.707 13.707L4.293 12.293 8.586 8 4.293 3.707 5.707 2.293 11.414 8 5.707 13.707z"></path></svg></span></span></span></a>
</div>
</div>
<div class="container-child ">
<div class="cmp-link" data-testid="cmp-button">
<a href="/appointments" class="cmp-anchor--plain cmp-button cmp-button__link " id="button-3172dbf3c1" data-cmp-data-layer="{" target":"request="" appointment","category":"global-header","action":"expanded|care="" at="" mayo="" clinic"}"=""><span aria-hidden="false" class="cmp-button__inner cmp-button__inner--width-full cmp-button__inner--type-text cmp-button__inner--focus-primary "><span class="cmp-button__inner-wrapper"><span class="cmp-button__inner-main"><span role="text" class="cmp-button__text"> <!-- -->Request Appointment</span></span><span class="cmp-icon icon__chevron-right cmp-icon--size-16"><svg data-name="32x32-Guides" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 16 16"><path d="M5.707 13.707L4.293 12.293 8.586 8 4.293 3.707 5.707 2.293 11.414 8 5.707 13.707z"></path></svg></span></span></span></a>
</div>
</div>
<div class="container-child ">
<div class="cmp-link" data-testid="cmp-button">
<a href="/appointments/find-a-doctor" class="cmp-anchor--plain cmp-button cmp-button__link " id="button-20f3a740fa" data-cmp-data-layer="{" target":"find="" a="" doctor","category":"global-header","action":"expanded|care="" at="" mayo="" clinic"}"=""><span aria-hidden="false" class="cmp-button__inner cmp-button__inner--width-full cmp-button__inner--type-text cmp-button__inner--focus-primary "><span class="cmp-button__inner-wrapper"><span class="cmp-button__inner-main"><span role="text" class="cmp-button__text"> <!-- -->Find a Doctor</span></span><span class="cmp-icon icon__chevron-right cmp-icon--size-16"><svg data-name="32x32-Guides" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 16 16"><path d="M5.707 13.707L4.293 12.293 8.586 8 4.293 3.707 5.707 2.293 11.414 8 5.707 13.707z"></path></svg></span></span></span></a>
</div>
</div>
<div class="container-child ">
<div class="cmp-link" data-testid="cmp-button">
<a href="/locations" class="cmp-anchor--plain cmp-button cmp-button__link " id="button-bb2e71f694" data-cmp-data-layer="{" target":"locations","category":"global-header","action":"expanded|care="" at="" mayo="" clinic"}"=""><span aria-hidden="false" class="cmp-button__inner cmp-button__inner--width-full cmp-button__inner--type-navigation cmp-button__inner--focus-primary "><span class="cmp-button__inner-wrapper"><span class="cmp-button__inner-main"><span role="text" class="cmp-button__text"> <!-- -->Locations</span></span><span class="cmp-icon icon__chevron-right cmp-icon--size-16"><svg data-name="32x32-Guides" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 16 16"><path d="M5.707 13.707L4.293 12.293 8.586 8 4.293 3.707 5.707 2.293 11.414 8 5.707 13.707z"></path></svg></span></span></span></a>
</div>
</div>
<div class="container-child ">
<div class="cmp-link" data-testid="cmp-button">
<a href="https://www.mayo.edu/research/clinical-trials" class="cmp-anchor--plain cmp-button cmp-button__link " id="button-dfc2de4642" data-cmp-data-layer="{" target":"clinical="" trials","category":"global-header","action":"expanded|care="" at="" mayo="" clinic"}"=""><span aria-hidden="false" class="cmp-button__inner cmp-button__inner--width-full cmp-button__inner--type-text cmp-button__inner--focus-primary "><span class="cmp-button__inner-wrapper"><span class="cmp-button__inner-main"><span role="text" class="cmp-button__text"> <!-- -->Clinical Trials</span></span><span class="cmp-icon icon__chevron-right cmp-icon--size-16"><svg data-name="32x32-Guides" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 16 16"><path d="M5.707 13.707L4.293 12.293 8.586 8 4.293 3.707 5.707 2.293 11.414 8 5.707 13.707z"></path></svg></span></span></span></a>
</div>
</div>
</div>
<div><!-- googleon: all --></div>
</div>
<div class="container-child aem-GridColumn--mayo_large--none aem-GridColumn--mayo_medium--none">
<div><!-- googleoff: all --></div>
<div class="aem-container " id="">
<div class="container-child ">
<div class="cmp-link" data-testid="cmp-button">
<a href="https://connect.mayoclinic.org" class="cmp-anchor--plain cmp-button cmp-button__link " id="button-96c25bf3fa" data-cmp-data-layer="{" target":"connect="" to="" support="" groups","category":"global-header","action":"expanded|care="" at="" mayo="" clinic"}"=""><span aria-hidden="false" class="cmp-button__inner cmp-button__inner--width-full cmp-button__inner--type-navigation cmp-button__inner--focus-primary "><span class="cmp-button__inner-wrapper"><span class="cmp-button__inner-main"><span role="text" class="cmp-button__text"> <!-- -->Connect to Support Groups</span></span><span class="cmp-icon icon__chevron-right cmp-icon--size-16"><svg data-name="32x32-Guides" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 16 16"><path d="M5.707 13.707L4.293 12.293 8.586 8 4.293 3.707 5.707 2.293 11.414 8 5.707 13.707z"></path></svg></span></span></span></a>
</div>
</div>
<div class="container-child ">
<div class="cmp-link" data-testid="cmp-button">
<a href="/patient-visitor-guide" class="cmp-anchor--plain cmp-button cmp-button__link " id="button-6f33b1b234" data-cmp-data-layer="{" target":"patient="" &="" visitor="" guide","category":"global-header","action":"expanded|care="" at="" mayo="" clinic"}"=""><span aria-hidden="false" class="cmp-button__inner cmp-button__inner--width-full cmp-button__inner--type-text cmp-button__inner--focus-primary "><span class="cmp-button__inner-wrapper"><span class="cmp-button__inner-main"><span role="text" class="cmp-button__text"> <!-- -->Patient & Visitor Guide</span></span><span class="cmp-icon icon__chevron-right cmp-icon--size-16"><svg data-name="32x32-Guides" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 16 16"><path d="M5.707 13.707L4.293 12.293 8.586 8 4.293 3.707 5.707 2.293 11.414 8 5.707 13.707z"></path></svg></span></span></span></a>
</div>
</div>
<div class="container-child ">
<div class="cmp-link" data-testid="cmp-button">
<a href="/patient-visitor-guide/billing-insurance" class="cmp-anchor--plain cmp-button cmp-button__link " id="button-d4aac85105" data-cmp-data-layer="{" target":"insurance="" &="" billing","category":"global-header","action":"expanded|care="" at="" mayo="" clinic"}"=""><span aria-hidden="false" class="cmp-button__inner cmp-button__inner--width-full cmp-button__inner--type-text cmp-button__inner--focus-primary "><span class="cmp-button__inner-wrapper"><span class="cmp-button__inner-main"><span role="text" class="cmp-button__text"> <!-- -->Insurance & Billing</span></span><span class="cmp-icon icon__chevron-right cmp-icon--size-16"><svg data-name="32x32-Guides" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 16 16"><path d="M5.707 13.707L4.293 12.293 8.586 8 4.293 3.707 5.707 2.293 11.414 8 5.707 13.707z"></path></svg></span></span></span></a>
</div>
</div>
<div class="container-child ">
<div class="cmp-link" data-testid="cmp-button">
<a href="/departments-centers" class="cmp-anchor--plain cmp-button cmp-button__link " id="button-6ef3165fc6" data-cmp-data-layer="{" target":"departments="" &="" centers","category":"global-header","action":"expanded|care="" at="" mayo="" clinic"}"=""><span aria-hidden="false" class="cmp-button__inner cmp-button__inner--width-full cmp-button__inner--type-text cmp-button__inner--focus-primary "><span class="cmp-button__inner-wrapper"><span class="cmp-button__inner-main"><span role="text" class="cmp-button__text"> <!-- -->Departments & Centers</span></span><span class="cmp-icon icon__chevron-right cmp-icon--size-16"><svg data-name="32x32-Guides" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 16 16"><path d="M5.707 13.707L4.293 12.293 8.586 8 4.293 3.707 5.707 2.293 11.414 8 5.707 13.707z"></path></svg></span></span></span></a>
</div>
</div>
<div class="container-child ">
<div class="cmp-link" data-testid="cmp-button">
<a href="/departments-centers/international" class="cmp-anchor--plain cmp-button cmp-button__link " id="button-c3b90973d7" data-cmp-data-layer="{" target":"international="" services","category":"global-header","action":"expanded|care="" at="" mayo="" clinic"}"=""><span aria-hidden="false" class="cmp-button__inner cmp-button__inner--width-full cmp-button__inner--type-text cmp-button__inner--focus-primary "><span class="cmp-button__inner-wrapper"><span class="cmp-button__inner-main"><span role="text" class="cmp-button__text"> <!-- -->International Services</span></span><span class="cmp-icon icon__chevron-right cmp-icon--size-16"><svg data-name="32x32-Guides" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 16 16"><path d="M5.707 13.707L4.293 12.293 8.586 8 4.293 3.707 5.707 2.293 11.414 8 5.707 13.707z"></path></svg></span></span></span></a>
</div>
</div>
<div class="container-child ">
<div class="cmp-link" data-testid="cmp-button">
<a href="/about-mayo-clinic/contact" class="cmp-anchor--plain cmp-button cmp-button__link " id="button-01e95d5096" data-cmp-data-layer="{" target":"contact="" us","category":"global-header","action":"expanded|care="" at="" mayo="" clinic"}"=""><span aria-hidden="false" class="cmp-button__inner cmp-button__inner--width-full cmp-button__inner--type-text cmp-button__inner--focus-primary "><span class="cmp-button__inner-wrapper"><span class="cmp-button__inner-main"><span role="text" class="cmp-button__text"> <!-- -->Contact Us</span></span><span class="cmp-icon icon__chevron-right cmp-icon--size-16"><svg data-name="32x32-Guides" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 16 16"><path d="M5.707 13.707L4.293 12.293 8.586 8 4.293 3.707 5.707 2.293 11.414 8 5.707 13.707z"></path></svg></span></span></span></a>
</div>
</div>
</div>
<div><!-- googleon: all --></div>
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<h1><a href="/diseases-conditions/depression/symptoms-causes/syc-20356007">Depression (major depressive disorder)</a></h1>
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<h4>What is depression? A Mayo Clinic expert explains.</h4>
<p>Learn more about depression from Craig Sawchuk, Ph.D., L.P., clinical psychologist at Mayo Clinic.</p>
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<p>Hi, I'm Dr. Craig Sawchuk, a clinical psychologist at Mayo Clinic. And I'm here to talk with you about depression. Whether you're looking for answers for yourself, a friend, or loved one, understanding the basics of depression can
help you take the next step.</p>
<strong>What is depression?</strong>
<p>Depression is a mood disorder that causes feelings of sadness that won't go away. Unfortunately, there's a lot of stigma around depression. Depression isn't a weakness or a character flaw. It's not about being in a bad mood, and
people who experience depression can't just snap out of it. Depression is a common, serious, and treatable condition. If you're experiencing depression, you're not alone. It honestly affects people of all ages and races and
biological sexes, income levels and educational backgrounds. Approximately one in six people will experience a major depressive episode at some point in their lifetime, while up to 16 million adults each year suffer from clinical
depression. There are many types of symptoms that make up depression. Emotionally, you may feel sad or down or irritable or even apathetic. Physically, the body really slows down. You feel tired. Your sleep is often disrupted. It's
really hard to get yourself motivated. Your thinking also changes. It can just be hard to concentrate. Your thoughts tend to be much more negative. You can be really hard on yourself, feel hopeless and helpless about things. And
even in some cases, have thoughts of not wanting to live. Behaviorally, you just want to pull back and withdraw from others, activities, and day-to-day responsibilities. These symptoms all work together to keep you trapped in a
cycle of depression. Symptoms of depression are different for everyone. Some symptoms may be a sign of another disorder or medical condition. That's why it's important to get an accurate diagnosis.</p>
<strong>What causes depression?</strong>
<p>While there's no single cause of depression, most experts believe there's a combination of biological, social, and psychological factors that contribute to depression risk. Biologically, we think about genetics or a family history
of depression, health conditions such as diabetes, heart disease or thyroid disorders, and even hormonal changes that happen over the lifespan, such as pregnancy and menopause. Changes in brain chemistry, especially disruptions in
neurotransmitters like serotonin, that play an important role in regulating many bodily functions, including mood, sleep, and appetite, are thought to play a particularly important role in depression. Socially stressful and
traumatic life events, limited access to resources such as food, housing, and health care, and a lack of social support all contribute to depression risk. Psychologically, we think of how negative thoughts and problematic coping
behaviors, such as avoidance and substance use, increase our vulnerability to depression.</p>
<p>The good news is that treatment helps. Effective treatments for depression exist and you do have options to see what works best for you. Lifestyle changes that improve sleep habits, exercise, and address underlying health
conditions can be an important first step. Medications such as antidepressants can be helpful in alleviating depressive symptoms. Therapy, especially cognitive behavioral therapy, teaches skills to better manage negative thoughts
and improve coping behaviors to help break you out of cycles of depression. Whatever the cause, remember that depression is not your fault and it can be treated.</p>
<p>To help diagnose depression, your health care provider may use a physical exam, lab tests, or a mental health evaluation. These results will help identify various treatment options that best fit your situation.</p>
<p>Help is available. You don't have to deal with depression by yourself. Take the next step and reach out. If you're hesitant to talk to a health care provider, talk to a friend or loved one about how to get help. Living with
depression isn't easy and you're not alone in your struggles. Always remember that effective treatments and supports are available to help you start feeling better. Want to learn more about depression? Visit mayoclinic.org. Do take
care.</p>
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<p>Depression is a mood disorder that causes a persistent feeling of sadness and loss of interest. Also called major depressive disorder or clinical depression, it affects how you feel, think and behave and can lead to a variety of
emotional and physical problems. You may have trouble doing normal day-to-day activities, and sometimes you may feel as if life isn't worth living.</p>
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<p>More than just a bout of the blues, depression isn't a weakness and you can't simply "snap out" of it. Depression may require long-term treatment. But don't get discouraged. Most people with depression feel better with medication,
psychotherapy or both.</p>
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<h2>Symptoms</h2>
<p>Although depression may occur only once during your life, people typically have multiple episodes. During these episodes, symptoms occur most of the day, nearly every day and may include:</p>
<ul>
<li>Feelings of sadness, tearfulness, emptiness or hopelessness</li>
<li>Angry outbursts, irritability or frustration, even over small matters</li>
<li>Loss of interest or pleasure in most or all normal activities, such as sex, hobbies or sports</li>
<li>Sleep disturbances, including insomnia or sleeping too much</li>
<li>Tiredness and lack of energy, so even small tasks take extra effort</li>
<li>Reduced appetite and weight loss or increased cravings for food and weight gain</li>
<li>Anxiety, agitation or restlessness</li>
<li>Slowed thinking, speaking or body movements</li>
<li>Feelings of worthlessness or guilt, fixating on past failures or self-blame</li>
<li>Trouble thinking, concentrating, making decisions and remembering things</li>
<li>Frequent or recurrent thoughts of death, suicidal thoughts, suicide attempts or suicide</li>
<li>Unexplained physical problems, such as back pain or headaches</li>
</ul>
<p>For many people with depression, symptoms usually are severe enough to cause noticeable problems in day-to-day activities, such as work, school, social activities or relationships with others. Some people may feel generally miserable
or unhappy without really knowing why.</p>
<h3>Depression symptoms in children and teens</h3>
<p>Common signs and symptoms of depression in children and teenagers are similar to those of adults, but there can be some differences.</p>
<ul>
<li>In younger children, symptoms of depression may include sadness, irritability, clinginess, worry, aches and pains, refusing to go to school, or being underweight.</li>
<li>In teens, symptoms may include sadness, irritability, feeling negative and worthless, anger, poor performance or poor attendance at school, feeling misunderstood and extremely sensitive, using recreational drugs or alcohol, eating
or sleeping too much, self-harm, loss of interest in normal activities, and avoidance of social interaction.</li>
</ul>
<h3>Depression symptoms in older adults</h3>
<p>Depression is not a normal part of growing older, and it should never be taken lightly. Unfortunately, depression often goes undiagnosed and untreated in older adults, and they may feel reluctant to seek help. Symptoms of depression
may be different or less obvious in older adults, such as:</p>
<ul>
<li>Memory difficulties or personality changes</li>
<li>Physical aches or pain</li>
<li>Fatigue, loss of appetite, sleep problems or loss of interest in sex — not caused by a medical condition or medication</li>
<li>Often wanting to stay at home, rather than going out to socialize or doing new things</li>
<li>Suicidal thinking or feelings, especially in older men</li>
</ul>
<h3>When to see a doctor</h3>
<p>If you feel depressed, make an appointment to see your doctor or mental health professional as soon as you can. If you're reluctant to seek treatment, talk to a friend or loved one, any health care professional, a faith leader, or
someone else you trust.</p>
<h3>When to get emergency help</h3>
<p>If you think you may hurt yourself or attempt suicide, call 911 in the U.S. or your local emergency number immediately.</p>
<p>Also consider these options if you're having suicidal thoughts:</p>
<ul>
<li>Call your doctor or mental health professional.</li>
<li>Contact a suicide hotline.</li>
<ul>
<li>In the U.S., call or text 988 to reach the <a href="https://988lifeline.org/talk-to-someone-now/">988 Suicide & Crisis Lifeline, available</a> 24 hours a day, seven days a week. Or use the
<a href="https://988lifeline.org/chat/">Lifeline Chat</a>. Services are free and confidential.</li>
<li>U.S. veterans or service members who are in crisis can call 988 and then press “1” for the <a href="https://www.veteranscrisisline.net/">Veterans Crisis Line</a>. Or text 838255. Or
<a href="https://www.veteranscrisisline.net/get-help-now/chat/">chat online</a>.</li>
<li>The Suicide & Crisis Lifeline in the U.S. has a Spanish language phone line at 1-888-628-9454 (toll-free).</li>
</ul>
<li>Reach out to a close friend or loved one.</li>
<li>Contact a minister, spiritual leader or someone else in your faith community.</li>
</ul>
<p>If you have a loved one who is in danger of suicide or has made a suicide attempt, make sure someone stays with that person. Call 911 or your local emergency number immediately. Or, if you think you can do so safely, take the person to
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<h2>Causes</h2>
<p>It's not known exactly what causes depression. As with many mental disorders, a variety of factors may be involved, such as:</p>
<ul>
<li><strong>Biological differences.</strong> People with depression appear to have physical changes in their brains. The significance of these changes is still uncertain, but may eventually help pinpoint causes.</li>
<li><strong>Brain chemistry.</strong> Neurotransmitters are naturally occurring brain chemicals that likely play a role in depression. Recent research indicates that changes in the function and effect of these neurotransmitters and how
they interact with neurocircuits involved in maintaining mood stability may play a significant role in depression and its treatment.</li>
<li><strong>Hormones.</strong> Changes in the body's balance of hormones may be involved in causing or triggering depression. Hormone changes can result with pregnancy and during the weeks or months after delivery (postpartum) and from
thyroid problems, menopause or a number of other conditions.</li>
<li><strong>Inherited traits.</strong> Depression is more common in people whose blood relatives also have this condition. Researchers are trying to find genes that may be involved in causing depression.</li>
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<h2>Risk factors</h2>
<p>Depression often begins in the teens, 20s or 30s, but it can happen at any age. More women than men are diagnosed with depression, but this may be due in part because women are more likely to seek treatment.</p>
<p>Factors that seem to increase the risk of developing or triggering depression include:</p>
<ul>
<li>Certain personality traits, such as low self-esteem and being too dependent, self-critical or pessimistic</li>
<li>Traumatic or stressful events, such as physical or sexual abuse, the death or loss of a loved one, a difficult relationship, or financial problems</li>
<li>Blood relatives with a history of depression, bipolar disorder, alcoholism or suicide</li>
<li>Being lesbian, gay, bisexual or transgender, or having variations in the development of genital organs that aren't clearly male or female (intersex) in an unsupportive situation</li>
<li>History of other mental health disorders, such as anxiety disorder, eating disorders or post-traumatic stress disorder</li>
<li>Abuse of alcohol or recreational drugs</li>
<li>Serious or chronic illness, including cancer, stroke, chronic pain or heart disease</li>
<li>Certain medications, such as some high blood pressure medications or sleeping pills (talk to your doctor before stopping any medication)</li>
</ul>
<h2>Complications</h2>
<p>Depression is a serious disorder that can take a terrible toll on you and your family. Depression often gets worse if it isn't treated, resulting in emotional, behavioral and health problems that affect every area of your life.</p>
<p>Examples of complications associated with depression include:</p>
<ul>
<li>Excess weight or obesity, which can lead to heart disease and diabetes</li>
<li>Pain or physical illness</li>
<li>Alcohol or drug misuse</li>
<li>Anxiety, panic disorder or social phobia</li>
<li>Family conflicts, relationship difficulties, and work or school problems</li>
<li>Social isolation</li>
<li>Suicidal feelings, suicide attempts or suicide</li>
<li>Self-mutilation, such as cutting</li>
<li>Premature death from medical conditions</li>
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<h2>Prevention</h2>
<p>There's no sure way to prevent depression. However, these strategies may help.</p>
<ul>
<li><strong>Take steps to control stress,</strong> to increase your resilience and boost your self-esteem.</li>
<li><strong>Reach out to family and friends,</strong> especially in times of crisis, to help you weather rough spells.</li>
<li><strong>Get treatment at the earliest sign of a problem</strong> to help prevent depression from worsening.</li>
<li><strong>Consider getting long-term maintenance treatment</strong> to help prevent a relapse of symptoms.</li>
</ul>
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<div class="thin-content-by"><a href="/about-this-site/meet-our-medical-editors">By Mayo Clinic Staff</a></div>
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<p>
<a href="/diseases-conditions/depression/care-at-mayo-clinic/mac-20356018">Depression (major depressive disorder) care at Mayo Clinic</a>
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<div class="pubdate"> Oct. 14, 2022 </div>
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<ol>
<li>Brown AY. Allscripts EPSi. Mayo Clinic, Rochester, Minn. Nov. 17, 2016.</li>
<li>Research report: Psychiatry and psychology, 2016-2017. Mayo Clinic. http://www.mayo.edu/research/departments-divisions/department-psychiatry-psychology/overview?_ga=1.199925222.939187614.1464371889. Accessed Jan. 23, 2017.</li>
<li>Depressive disorders. In: Diagnostic and Statistical Manual of Mental Disorders DSM-5. 5th ed. Arlington, Va.: American Psychiatric Association; 2013. http://www.psychiatryonline.org. Accessed Jan. 23, 2017.</li>
<li>Depression. National Institute of Mental Health. https://www.nimh.nih.gov/health/topics/depression/index.shtml. Accessed Jan. 23, 2017.</li>
<li>Depression. National Alliance on Mental Illness. http://www.nami.org/Learn-More/Mental-Health-Conditions/Depression/Overview. Accessed Jan. 23, 2017.</li>
<li>Depression: What you need to know. National Institute of Mental Health. https://www.nimh.nih.gov/health/publications/depression-what-you-need-to-know/index.shtml. Accessed Jan. 23, 2017.</li>
<li>What is depression? American Psychiatric Association. https://www.psychiatry.org/patients-families/depression/what-is-depression. Accessed Jan. 23, 2017.</li>
<li>Depression. NIH Senior Health. https://nihseniorhealth.gov/depression/aboutdepression/01.html. Accessed Jan. 23, 2017.</li>
<li>Children’s mental health: Anxiety and depression. Centers for Disease Control and Prevention. https://www.cdc.gov/childrensmentalhealth/depression.html#depression. Accessed. Jan. 23, 2017.</li>
<li>Depression and complementary health approaches: What the science says. National Center for Complementary and Integrative Health. https://nccih.nih.gov/health/providers/digest/depression-science. Accessed Jan. 23, 2017.</li>
<li>Depression. Natural Medicines. https://naturalmedicines.therapeuticresearch.com/databases/medical-conditions/d/depression.aspx. Accessed Jan. 23, 2017.</li>
<li>Natural medicines in the clinical management of depression. Natural Medicines. http://naturaldatabase.therapeuticresearch.com/ce/CECourse.aspx?cs=naturalstandard&s=ND&pm=5&pc=15-111. Accessed Jan. 23, 2017.</li>
<li>The road to resilience. American Psychological Association. http://www.apa.org/helpcenter/road-resilience.aspx. Accessed Jan. 23, 2017.</li>
<li>Simon G, et al. Unipolar depression in adults: Choosing initial treatment. http://www.uptodate.com/home. Accessed Jan. 23, 2017.</li>
<li>Stewart D, et al. Risks of antidepressants during pregnancy: Selective serotonin reuptake inhibitors (SSRIs). http://www.uptodate.com/home. Accessed Jan. 23, 2017.</li>
<li>Kimmel MC, et al. Safety of infant exposure to antidepressants and benzodiazepines through breastfeeding. http://www.uptodate.com/home. Accessed Jan. 23, 2017.</li>
<li>Bipolar and related disorders. In: Diagnostic and Statistical Manual of Mental Disorders DSM-5. 5th ed. Arlington, Va.: American Psychiatric Association; 2013. http://www.psychiatryonline.org. Accessed Jan. 23, 2017.</li>
<li>Hirsch M, et al. Monoamine oxidase inhibitors (MAOIs) for treating depressed adults. http://www.uptodate.com/home. Accessed Jan. 24, 2017.</li>
<li>Hall-Flavin DK (expert opinion). Mayo Clinic, Rochester, Minn. Jan. 31, 2017.</li>
<li>Krieger CA (expert opinion). Mayo Clinic, Rochester, Minn. Feb. 2, 2017.</li>
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<a href="https://alumniassociation.mayo.edu" class="cmp-anchor--plain cmp-button cmp-button__link " id="button-a9993ca021" data-cmp-data-layer="{" target":"mayo="" clinic="" alumni="" association","category":"global-footer","action":"click"}"=""><span aria-hidden="false" class="cmp-button__inner cmp-button__inner--width-full cmp-button__inner--type-text-xsmall cmp-button__inner--color-primary-inverse "><span class="cmp-button__inner-wrapper"><span class="cmp-button__inner-main"><span role="text" class="cmp-button__text"> <!-- -->Mayo Clinic Alumni Association</span></span><span class="cmp-icon icon__chevron-right cmp-icon--size-16"><svg data-name="32x32-Guides" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 16 16"><path d="M5.707 13.707L4.293 12.293 8.586 8 4.293 3.707 5.707 2.293 11.414 8 5.707 13.707z"></path></svg></span></span></span></a>
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<a href="/medical-professionals/provider-relations/refer-patient" class="cmp-anchor--plain cmp-button cmp-button__link " id="button-a6de834448" data-cmp-data-layer="{" target":"refer="" a="" patient","category":"global-footer","action":"click"}"=""><span aria-hidden="false" class="cmp-button__inner cmp-button__inner--width-full cmp-button__inner--type-text-xsmall cmp-button__inner--color-primary-inverse "><span class="cmp-button__inner-wrapper"><span class="cmp-button__inner-main"><span role="text" class="cmp-button__text"> <!-- -->Refer a Patient</span></span><span class="cmp-icon icon__chevron-right cmp-icon--size-16"><svg data-name="32x32-Guides" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 16 16"><path d="M5.707 13.707L4.293 12.293 8.586 8 4.293 3.707 5.707 2.293 11.414 8 5.707 13.707z"></path></svg></span></span></span></a>
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<a href="/departments-centers/international/international-business-collaborations" class="cmp-anchor--plain cmp-button cmp-button__link " id="button-0f17273797" data-cmp-data-layer="{" target":"international="" business="" collaborations","category":"global-footer","action":"click"}"=""><span aria-hidden="false" class="cmp-button__inner cmp-button__inner--width-full cmp-button__inner--type-text-xsmall cmp-button__inner--color-primary-inverse "><span class="cmp-button__inner-wrapper"><span class="cmp-button__inner-main"><span role="text" class="cmp-button__text"> <!-- -->International Business Collaborations</span></span><span class="cmp-icon icon__chevron-right cmp-icon--size-16"><svg data-name="32x32-Guides" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 16 16"><path d="M5.707 13.707L4.293 12.293 8.586 8 4.293 3.707 5.707 2.293 11.414 8 5.707 13.707z"></path></svg></span></span></span></a>
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<a href="/about-mayo-clinic/facilities-and-real-estate" class="cmp-anchor--plain cmp-button cmp-button__link " id="button-d065cd4572" data-cmp-data-layer="{" target":"facilities="" &="" real="" estate","category":"global-footer","action":"click"}"=""><span aria-hidden="false" class="cmp-button__inner cmp-button__inner--width-full cmp-button__inner--type-text-xsmall cmp-button__inner--color-primary-inverse "><span class="cmp-button__inner-wrapper"><span class="cmp-button__inner-main"><span role="text" class="cmp-button__text"> <!-- -->Facilities & Real Estate</span></span><span class="cmp-icon icon__chevron-right cmp-icon--size-16"><svg data-name="32x32-Guides" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 16 16"><path d="M5.707 13.707L4.293 12.293 8.586 8 4.293 3.707 5.707 2.293 11.414 8 5.707 13.707z"></path></svg></span></span></span></a>
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<a href="/about-mayo-clinic/supplier-information" class="cmp-anchor--plain cmp-button cmp-button__link " id="button-64b41ac243" data-cmp-data-layer="{" target":"supplier="" information","category":"global-footer","action":"click"}"=""><span aria-hidden="false" class="cmp-button__inner cmp-button__inner--width-full cmp-button__inner--type-text-xsmall cmp-button__inner--color-primary-inverse "><span class="cmp-button__inner-wrapper"><span class="cmp-button__inner-main"><span role="text" class="cmp-button__text"> <!-- -->Supplier Information</span></span><span class="cmp-icon icon__chevron-right cmp-icon--size-16"><svg data-name="32x32-Guides" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 16 16"><path d="M5.707 13.707L4.293 12.293 8.586 8 4.293 3.707 5.707 2.293 11.414 8 5.707 13.707z"></path></svg></span></span></span></a>
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<div><!-- googleon: all --></div>
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<div><!-- googleon: all --></div>
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<div
class="aem-GridColumn aem-GridColumn--default--3 aem-GridColumn--mayo_x-large--4 aem-GridColumn--mayo_x-small--12 aem-GridColumn--mayo_large--4 aem-GridColumn--mayo_medium--6 aem-GridColumn--offset--mayo_medium--0 aem-GridColumn--mayo_medium--hide aem-GridColumn--mayo_small--12 aem-GridColumn">
<div><!-- googleoff: all --></div>
<div class="aem-container cmp-container--column-vertical-padding-1x aem-Grid aem-Grid--12 aem-Grid--default--12 " id="">
<div class="aem-GridColumn aem-GridColumn--default--12 aem-GridColumn">
<div class="cmp-title" data-testid="cmp-title">
<h2 id="title-ac1df09b38" class=" cmp-title__text--body-serif-small-bold cmp-title__text--color-primary-inverse">
<div class="cmp-link" data-testid="cmp-link">
<a href="https://college.mayo.edu" class="cmp-anchor--plain" data-cmp-data-layer="{" target":"students","category":"global-footer","action":"click"}"=""><span role="text" class="cmp-title__inner">Students <!-- --> <span class="cmp-title__no-break"> <span class="cmp-icon icon__chevron-right cmp-icon--size-16"><svg data-name="32x32-Guides" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 16 16"><path d="M5.707 13.707L4.293 12.293 8.586 8 4.293 3.707 5.707 2.293 11.414 8 5.707 13.707z"></path></svg></span></span></span></a>
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</h2>
</div>
</div>
<div class="aem-GridColumn aem-GridColumn--default--12 aem-GridColumn">
<div><!-- googleoff: all --></div>
<ul class="cmp-list__container cmp-list--footer-links aem-Grid aem-Grid--12 aem-Grid--default--12 " id="" data-testid="cmp-list">
<li class="cmp-list__item aem-GridColumn aem-GridColumn--default--12">
<div class="cmp-link" data-testid="cmp-button">
<a href="https://college.mayo.edu/admissions-and-tuition/" class="cmp-anchor--plain cmp-button cmp-button__link " id="button-2206c90465" data-cmp-data-layer="{" target":"admissions="" requirements","category":"global-footer","action":"click"}"=""><span aria-hidden="false" class="cmp-button__inner cmp-button__inner--width-full cmp-button__inner--type-text-xsmall cmp-button__inner--color-primary-inverse "><span class="cmp-button__inner-wrapper"><span class="cmp-button__inner-main"><span role="text" class="cmp-button__text"> <!-- -->Admissions Requirements</span></span><span class="cmp-icon icon__chevron-right cmp-icon--size-16"><svg data-name="32x32-Guides" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 16 16"><path d="M5.707 13.707L4.293 12.293 8.586 8 4.293 3.707 5.707 2.293 11.414 8 5.707 13.707z"></path></svg></span></span></span></a>
</div>
</li>
<li class="cmp-list__item aem-GridColumn aem-GridColumn--default--12">
<div class="cmp-link" data-testid="cmp-button">
<a href="https://college.mayo.edu/academics/" class="cmp-anchor--plain cmp-button cmp-button__link " id="button-4bd4e4f1e5" data-cmp-data-layer="{" target":"degree="" programs","category":"global-footer","action":"click"}"=""><span aria-hidden="false" class="cmp-button__inner cmp-button__inner--width-full cmp-button__inner--type-text-xsmall cmp-button__inner--color-primary-inverse "><span class="cmp-button__inner-wrapper"><span class="cmp-button__inner-main"><span role="text" class="cmp-button__text"> <!-- -->Degree Programs</span></span><span class="cmp-icon icon__chevron-right cmp-icon--size-16"><svg data-name="32x32-Guides" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 16 16"><path d="M5.707 13.707L4.293 12.293 8.586 8 4.293 3.707 5.707 2.293 11.414 8 5.707 13.707z"></path></svg></span></span></span></a>
</div>
</li>
<li class="cmp-list__item aem-GridColumn aem-GridColumn--default--12">
<div class="cmp-link" data-testid="cmp-button">
<a href="https://login.edlink.mayo.edu/authenticationendpoint/login.do?commonAuthCallerPath=/samlsso&forceAuth=false&passiveAuth=false&tenantDomain=carbon.super&sessionDataKey=5575b8c9-06e5-4e99-bee0-0681c7a12289&relyingParty=LUM6P_LuminisPortal&type=samlsso&sp=LUM6P_LuminisPortal&isSaaSApp=false&authenticators=BasicAuthenticator:LOCAL" class="cmp-anchor--plain cmp-button cmp-button__link " id="button-bf84cd191f" data-cmp-data-layer="{" target":"student="" &="" faculty="" portal","category":"global-footer","action":"click"}"=""><span aria-hidden="false" class="cmp-button__inner cmp-button__inner--width-full cmp-button__inner--type-text-xsmall cmp-button__inner--color-primary-inverse "><span class="cmp-button__inner-wrapper"><span class="cmp-button__inner-main"><span role="text" class="cmp-button__text"> <!-- -->Student & Faculty Portal</span></span><span class="cmp-icon icon__chevron-right cmp-icon--size-16"><svg data-name="32x32-Guides" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 16 16"><path d="M5.707 13.707L4.293 12.293 8.586 8 4.293 3.707 5.707 2.293 11.414 8 5.707 13.707z"></path></svg></span></span></span></a>
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</li>
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<div><!-- googleon: all --></div>
</div>
</div>
<div><!-- googleon: all --></div>
</div>
</div>
<div><!-- googleon: all --></div>
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<div
class="aem-GridColumn aem-GridColumn--default--4 aem-GridColumn--offset--default--1 aem-GridColumn--default--none aem-GridColumn--mayo_x-large--4 aem-GridColumn--offset--mayo_x-large--0 aem-GridColumn--mayo_x-large--none aem-GridColumn--mayo_medium--6 aem-GridColumn--offset--mayo_medium--0 aem-GridColumn--mayo_medium--none aem-GridColumn--mayo_x-small--12 aem-GridColumn--offset--mayo_x-small--0 aem-GridColumn--mayo_x-small--none aem-GridColumn--mayo_large--4 aem-GridColumn--offset--mayo_large--0 aem-GridColumn--mayo_large--none aem-GridColumn--mayo_small--12 aem-GridColumn--offset--mayo_small--0 aem-GridColumn--mayo_small--none aem-GridColumn">
<div><!-- googleoff: all --></div>
<div class="aem-container cmp-container--navigation aem-Grid aem-Grid--4 aem-Grid--default--4 aem-Grid--mayo_x-large--4 aem-Grid--mayo_medium--6 aem-Grid--mayo_x-small--12 aem-Grid--mayo_large--4 aem-Grid--mayo_small--12 " id="">
<div
class="aem-GridColumn aem-GridColumn--default--4 aem-GridColumn--mayo_x-large--4 aem-GridColumn--offset--mayo_x-large--0 aem-GridColumn--mayo_x-large--hide aem-GridColumn--mayo_medium--6 aem-GridColumn--mayo_large--4 aem-GridColumn--offset--mayo_large--0 aem-GridColumn--mayo_large--hide aem-GridColumn--mayo_x-small--12 aem-GridColumn--offset--mayo_x-small--0 aem-GridColumn--mayo_x-small--hide aem-GridColumn--mayo_small--12 aem-GridColumn--offset--mayo_small--0 aem-GridColumn--mayo_small--hide aem-GridColumn">
<div><!-- googleoff: all --></div>
<div class="aem-container cmp-container--column-vertical-padding-1x aem-Grid aem-Grid--12 aem-Grid--default--12 " id="">
<div class="aem-GridColumn aem-GridColumn--default--12 aem-GridColumn">
<div class="cmp-title" data-testid="cmp-title">
<h2 id="title-2ea73cfd58" class=" cmp-title__text--body-serif-small-bold cmp-title__text--color-primary-inverse">
<div class="cmp-link" data-testid="cmp-link">
<a href="https://college.mayo.edu" class="cmp-anchor--plain" data-cmp-data-layer="{" target":"students","category":"global-footer","action":"click"}"=""><span role="text" class="cmp-title__inner">Students<!-- --> <span class="cmp-title__no-break"> <span class="cmp-icon icon__chevron-right cmp-icon--size-16"><svg data-name="32x32-Guides" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 16 16"><path d="M5.707 13.707L4.293 12.293 8.586 8 4.293 3.707 5.707 2.293 11.414 8 5.707 13.707z"></path></svg></span></span></span></a>
</div>
</h2>
</div>
</div>
<div class="aem-GridColumn aem-GridColumn--default--12 aem-GridColumn">
<div><!-- googleoff: all --></div>
<ul class="cmp-list__container cmp-list--footer-links aem-Grid aem-Grid--12 aem-Grid--default--12 " id="" data-testid="cmp-list">
<li class="cmp-list__item aem-GridColumn aem-GridColumn--default--12">
<div class="cmp-link" data-testid="cmp-button">
<a href="https://college.mayo.edu" class="cmp-anchor--plain cmp-button cmp-button__link " id="button-9c2340ee13" data-cmp-data-layer="{" target":"degree="" programs","category":"global-footer","action":"click"}"=""><span aria-hidden="false" class="cmp-button__inner cmp-button__inner--width-full cmp-button__inner--type-text-xsmall cmp-button__inner--color-primary-inverse "><span class="cmp-button__inner-wrapper"><span class="cmp-button__inner-main"><span role="text" class="cmp-button__text"> <!-- -->Degree Programs</span></span><span class="cmp-icon icon__chevron-right cmp-icon--size-16"><svg data-name="32x32-Guides" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 16 16"><path d="M5.707 13.707L4.293 12.293 8.586 8 4.293 3.707 5.707 2.293 11.414 8 5.707 13.707z"></path></svg></span></span></span></a>
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</li>
<li class="cmp-list__item aem-GridColumn aem-GridColumn--default--12">
<div class="cmp-link" data-testid="cmp-button">
<a href="https://college.mayo.edu/admissions-and-tuition/" class="cmp-anchor--plain cmp-button cmp-button__link " id="button-ccf09cb111" data-cmp-data-layer="{" target":"admissions="" requirements","category":"global-footer","action":"click"}"=""><span aria-hidden="false" class="cmp-button__inner cmp-button__inner--width-full cmp-button__inner--type-text-xsmall cmp-button__inner--color-primary-inverse "><span class="cmp-button__inner-wrapper"><span class="cmp-button__inner-main"><span role="text" class="cmp-button__text"> <!-- -->Admissions Requirements</span></span><span class="cmp-icon icon__chevron-right cmp-icon--size-16"><svg data-name="32x32-Guides" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 16 16"><path d="M5.707 13.707L4.293 12.293 8.586 8 4.293 3.707 5.707 2.293 11.414 8 5.707 13.707z"></path></svg></span></span></span></a>
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</li>
<li class="cmp-list__item aem-GridColumn aem-GridColumn--default--12">
<div class="cmp-link" data-testid="cmp-button">
<a href="https://login.edlink.mayo.edu/authenticationendpoint/login.do?commonAuthCallerPath=/samlsso&forceAuth=false&passiveAuth=false&tenantDomain=carbon.super&sessionDataKey=5575b8c9-06e5-4e99-bee0-0681c7a12289&relyingParty=LUM6P_LuminisPortal&type=samlsso&sp=LUM6P_LuminisPortal&isSaaSApp=false&authenticators=BasicAuthenticator:LOCAL" class="cmp-anchor--plain cmp-button cmp-button__link " id="button-7e96bbe076" data-cmp-data-layer="{" target":"student="" &="" faculty="" portal","category":"global-footer","action":"click"}"=""><span aria-hidden="false" class="cmp-button__inner cmp-button__inner--width-full cmp-button__inner--type-text-xsmall cmp-button__inner--color-primary-inverse "><span class="cmp-button__inner-wrapper"><span class="cmp-button__inner-main"><span role="text" class="cmp-button__text"> <!-- -->Student & Faculty Portal</span></span><span class="cmp-icon icon__chevron-right cmp-icon--size-16"><svg data-name="32x32-Guides" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 16 16"><path d="M5.707 13.707L4.293 12.293 8.586 8 4.293 3.707 5.707 2.293 11.414 8 5.707 13.707z"></path></svg></span></span></span></a>
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<div><!-- googleon: all --></div>
</div>
</div>
<div><!-- googleon: all --></div>
</div>
<div class="aem-GridColumn aem-GridColumn--default--4 aem-GridColumn--mayo_x-large--4 aem-GridColumn--mayo_medium--6 aem-GridColumn--mayo_x-small--12 aem-GridColumn--mayo_large--4 aem-GridColumn--mayo_small--12 aem-GridColumn">
<div><!-- googleoff: all --></div>
<div class="aem-container cmp-container--column-vertical-padding-1x aem-Grid aem-Grid--12 aem-Grid--default--12 " id="">
<div class="aem-GridColumn aem-GridColumn--default--12 aem-GridColumn">
<div class="cmp-title" data-testid="cmp-title">
<h2 id="title-dc23cd13f2" class=" cmp-title__text--body-serif-small-bold cmp-title__text--color-primary-inverse">
<div class="cmp-link" data-testid="cmp-link">
<a href="https://www.mayo.edu/research" class="cmp-anchor--plain" data-cmp-data-layer="{" target":"researchers","category":"global-footer","action":"click"}"=""><span role="text" class="cmp-title__inner">Researchers<!-- --> <span class="cmp-title__no-break"> <span class="cmp-icon icon__chevron-right cmp-icon--size-16"><svg data-name="32x32-Guides" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 16 16"><path d="M5.707 13.707L4.293 12.293 8.586 8 4.293 3.707 5.707 2.293 11.414 8 5.707 13.707z"></path></svg></span></span></span></a>
</div>
</h2>
</div>
</div>
<div class="aem-GridColumn aem-GridColumn--default--12 aem-GridColumn">
<div><!-- googleoff: all --></div>
<ul class="cmp-list__container cmp-list--footer-links aem-Grid aem-Grid--12 aem-Grid--default--12 " id="" data-testid="cmp-list">
<li class="cmp-list__item aem-GridColumn aem-GridColumn--default--12">
<div class="cmp-link" data-testid="cmp-button">
<a href="https://www.mayo.edu/research/faculty" class="cmp-anchor--plain cmp-button cmp-button__link " id="button-9ad9df65ee" data-cmp-data-layer="{" target":"research="" faculty","category":"global-footer","action":"click"}"=""><span aria-hidden="false" class="cmp-button__inner cmp-button__inner--width-full cmp-button__inner--type-text-xsmall cmp-button__inner--color-primary-inverse "><span class="cmp-button__inner-wrapper"><span class="cmp-button__inner-main"><span role="text" class="cmp-button__text"> <!-- -->Research Faculty</span></span><span class="cmp-icon icon__chevron-right cmp-icon--size-16"><svg data-name="32x32-Guides" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 16 16"><path d="M5.707 13.707L4.293 12.293 8.586 8 4.293 3.707 5.707 2.293 11.414 8 5.707 13.707z"></path></svg></span></span></span></a>
</div>
</li>
<li class="cmp-list__item aem-GridColumn aem-GridColumn--default--12">
<div class="cmp-link" data-testid="cmp-button">
<a href="https://www.mayo.edu/research/labs" class="cmp-anchor--plain cmp-button cmp-button__link " id="button-cdddbb4301" data-cmp-data-layer="{" target":"laboratories","category":"global-footer","action":"click"}"=""><span aria-hidden="false" class="cmp-button__inner cmp-button__inner--width-full cmp-button__inner--type-text-xsmall cmp-button__inner--color-primary-inverse "><span class="cmp-button__inner-wrapper"><span class="cmp-button__inner-main"><span role="text" class="cmp-button__text"> <!-- -->Laboratories</span></span><span class="cmp-icon icon__chevron-right cmp-icon--size-16"><svg data-name="32x32-Guides" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 16 16"><path d="M5.707 13.707L4.293 12.293 8.586 8 4.293 3.707 5.707 2.293 11.414 8 5.707 13.707z"></path></svg></span></span></span></a>
</div>
</li>
</ul>
<div><!-- googleon: all --></div>
</div>
</div>
<div><!-- googleon: all --></div>
</div>
<div class="aem-GridColumn aem-GridColumn--default--4 aem-GridColumn--mayo_x-large--4 aem-GridColumn--mayo_medium--6 aem-GridColumn--mayo_x-small--12 aem-GridColumn--mayo_large--4 aem-GridColumn--mayo_small--12 aem-GridColumn">
<div><!-- googleoff: all --></div>
<div class="aem-container cmp-container--column-vertical-padding-1x aem-Grid aem-Grid--12 aem-Grid--default--12 " id="">
<div class="aem-GridColumn aem-GridColumn--default--12 aem-GridColumn">
<div class="cmp-title" data-testid="cmp-title">
<h2 id="title-17fcb44baf" class=" cmp-title__text--body-serif-small-bold cmp-title__text--color-primary-inverse">
<div class="cmp-link" data-testid="cmp-link">
<a href="/departments-centers/international" class="cmp-anchor--plain" data-cmp-data-layer="{" target":"international="" patients","category":"global-footer","action":"click"}"=""><span role="text" class="cmp-title__inner">International<!-- --> <span class="cmp-title__no-break">Patients<!-- --> <span class="cmp-icon icon__chevron-right cmp-icon--size-16"><svg data-name="32x32-Guides" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 16 16"><path d="M5.707 13.707L4.293 12.293 8.586 8 4.293 3.707 5.707 2.293 11.414 8 5.707 13.707z"></path></svg></span></span></span></a>
</div>
</h2>
</div>
</div>
<div class="aem-GridColumn aem-GridColumn--default--12 aem-GridColumn">
<div><!-- googleoff: all --></div>
<ul class="cmp-list__container cmp-list--footer-links aem-Grid aem-Grid--12 aem-Grid--default--12 " id="" data-testid="cmp-list">
<li class="cmp-list__item aem-GridColumn aem-GridColumn--default--12">
<div class="cmp-link" data-testid="cmp-button">
<a href="/departments-centers/international/appointments" class="cmp-anchor--plain cmp-button cmp-button__link " id="button-83fc99de7b" data-cmp-data-layer="{" target":"appointments","category":"global-footer","action":"click"}"=""><span aria-hidden="false" class="cmp-button__inner cmp-button__inner--width-full cmp-button__inner--type-text-xsmall cmp-button__inner--color-primary-inverse "><span class="cmp-button__inner-wrapper"><span class="cmp-button__inner-main"><span role="text" class="cmp-button__text"> <!-- -->Appointments</span></span><span class="cmp-icon icon__chevron-right cmp-icon--size-16"><svg data-name="32x32-Guides" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 16 16"><path d="M5.707 13.707L4.293 12.293 8.586 8 4.293 3.707 5.707 2.293 11.414 8 5.707 13.707z"></path></svg></span></span></span></a>
</div>
</li>
<li class="cmp-list__item aem-GridColumn aem-GridColumn--default--12">
<div class="cmp-link" data-testid="cmp-button">
<a href="/departments-centers/international/financial-services" class="cmp-anchor--plain cmp-button cmp-button__link " id="button-cca326f163" data-cmp-data-layer="{" target":"financial="" services","category":"global-footer","action":"click"}"=""><span aria-hidden="false" class="cmp-button__inner cmp-button__inner--width-full cmp-button__inner--type-text-xsmall cmp-button__inner--color-primary-inverse "><span class="cmp-button__inner-wrapper"><span class="cmp-button__inner-main"><span role="text" class="cmp-button__text"> <!-- -->Financial Services</span></span><span class="cmp-icon icon__chevron-right cmp-icon--size-16"><svg data-name="32x32-Guides" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 16 16"><path d="M5.707 13.707L4.293 12.293 8.586 8 4.293 3.707 5.707 2.293 11.414 8 5.707 13.707z"></path></svg></span></span></span></a>
</div>
</li>
<li class="cmp-list__item aem-GridColumn aem-GridColumn--default--12">
<div class="cmp-link" data-testid="cmp-button">
<a href="/departments-centers/international/locations" class="cmp-anchor--plain cmp-button cmp-button__link " id="button-5e92046078" data-cmp-data-layer="{" target":"international="" locations="" &="" offices","category":"global-footer","action":"click"}"=""><span aria-hidden="false" class="cmp-button__inner cmp-button__inner--width-full cmp-button__inner--type-text-xsmall cmp-button__inner--color-primary-inverse "><span class="cmp-button__inner-wrapper"><span class="cmp-button__inner-main"><span role="text" class="cmp-button__text"> <!-- -->International Locations & Offices</span></span><span class="cmp-icon icon__chevron-right cmp-icon--size-16"><svg data-name="32x32-Guides" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 16 16"><path d="M5.707 13.707L4.293 12.293 8.586 8 4.293 3.707 5.707 2.293 11.414 8 5.707 13.707z"></path></svg></span></span></span></a>
</div>
</li>
</ul>
<div><!-- googleon: all --></div>
</div>
</div>
<div><!-- googleon: all --></div>
</div>
<div class="aem-GridColumn aem-GridColumn--default--4 aem-GridColumn--mayo_x-large--4 aem-GridColumn--mayo_medium--6 aem-GridColumn--mayo_x-small--12 aem-GridColumn--mayo_large--4 aem-GridColumn--mayo_small--12 aem-GridColumn">
<div><!-- googleoff: all --></div>
<div class="aem-container cmp-container--column-vertical-padding-1x aem-Grid aem-Grid--12 aem-Grid--default--12 " id="">
<div class="aem-GridColumn aem-GridColumn--default--12 aem-GridColumn">
<div class="cmp-title" data-testid="cmp-title">
<h2 id="title-10b65c524f" class=" cmp-title__text--body-serif-small-bold cmp-title__text--color-primary-inverse">
<div class="cmp-link" data-testid="cmp-link">
<a href="/patient-visitor-guide/billing-insurance/financial-assistance" class="cmp-anchor--plain" data-cmp-data-layer="{" target":"charitable="" care="" &="" financial="" assistance","category":"global-footer","action":"click"}"=""><span role="text" class="cmp-title__inner">Charitable Care & Financial<!-- --> <span class="cmp-title__no-break">Assistance<!-- --> <span class="cmp-icon icon__chevron-right cmp-icon--size-16"><svg data-name="32x32-Guides" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 16 16"><path d="M5.707 13.707L4.293 12.293 8.586 8 4.293 3.707 5.707 2.293 11.414 8 5.707 13.707z"></path></svg></span></span></span></a>
</div>
</h2>
</div>
</div>
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DEPRESSION (MAJOR DEPRESSIVE DISORDER)
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OVERVIEW
WHAT IS DEPRESSION? A MAYO CLINIC EXPERT EXPLAINS.
Learn more about depression from Craig Sawchuk, Ph.D., L.P., clinical
psychologist at Mayo Clinic.
Show transcript for video What is depression? A Mayo Clinic expert explains.
Hi, I'm Dr. Craig Sawchuk, a clinical psychologist at Mayo Clinic. And I'm here
to talk with you about depression. Whether you're looking for answers for
yourself, a friend, or loved one, understanding the basics of depression can
help you take the next step.
What is depression?
Depression is a mood disorder that causes feelings of sadness that won't go
away. Unfortunately, there's a lot of stigma around depression. Depression isn't
a weakness or a character flaw. It's not about being in a bad mood, and people
who experience depression can't just snap out of it. Depression is a common,
serious, and treatable condition. If you're experiencing depression, you're not
alone. It honestly affects people of all ages and races and biological sexes,
income levels and educational backgrounds. Approximately one in six people will
experience a major depressive episode at some point in their lifetime, while up
to 16 million adults each year suffer from clinical depression. There are many
types of symptoms that make up depression. Emotionally, you may feel sad or down
or irritable or even apathetic. Physically, the body really slows down. You feel
tired. Your sleep is often disrupted. It's really hard to get yourself
motivated. Your thinking also changes. It can just be hard to concentrate. Your
thoughts tend to be much more negative. You can be really hard on yourself, feel
hopeless and helpless about things. And even in some cases, have thoughts of not
wanting to live. Behaviorally, you just want to pull back and withdraw from
others, activities, and day-to-day responsibilities. These symptoms all work
together to keep you trapped in a cycle of depression. Symptoms of depression
are different for everyone. Some symptoms may be a sign of another disorder or
medical condition. That's why it's important to get an accurate diagnosis.
What causes depression?
While there's no single cause of depression, most experts believe there's a
combination of biological, social, and psychological factors that contribute to
depression risk. Biologically, we think about genetics or a family history of
depression, health conditions such as diabetes, heart disease or thyroid
disorders, and even hormonal changes that happen over the lifespan, such as
pregnancy and menopause. Changes in brain chemistry, especially disruptions in
neurotransmitters like serotonin, that play an important role in regulating many
bodily functions, including mood, sleep, and appetite, are thought to play a
particularly important role in depression. Socially stressful and traumatic life
events, limited access to resources such as food, housing, and health care, and
a lack of social support all contribute to depression risk. Psychologically, we
think of how negative thoughts and problematic coping behaviors, such as
avoidance and substance use, increase our vulnerability to depression.
The good news is that treatment helps. Effective treatments for depression exist
and you do have options to see what works best for you. Lifestyle changes that
improve sleep habits, exercise, and address underlying health conditions can be
an important first step. Medications such as antidepressants can be helpful in
alleviating depressive symptoms. Therapy, especially cognitive behavioral
therapy, teaches skills to better manage negative thoughts and improve coping
behaviors to help break you out of cycles of depression. Whatever the cause,
remember that depression is not your fault and it can be treated.
To help diagnose depression, your health care provider may use a physical exam,
lab tests, or a mental health evaluation. These results will help identify
various treatment options that best fit your situation.
Help is available. You don't have to deal with depression by yourself. Take the
next step and reach out. If you're hesitant to talk to a health care provider,
talk to a friend or loved one about how to get help. Living with depression
isn't easy and you're not alone in your struggles. Always remember that
effective treatments and supports are available to help you start feeling
better. Want to learn more about depression? Visit mayoclinic.org. Do take care.
Depression is a mood disorder that causes a persistent feeling of sadness and
loss of interest. Also called major depressive disorder or clinical depression,
it affects how you feel, think and behave and can lead to a variety of emotional
and physical problems. You may have trouble doing normal day-to-day activities,
and sometimes you may feel as if life isn't worth living.
More than just a bout of the blues, depression isn't a weakness and you can't
simply "snap out" of it. Depression may require long-term treatment. But don't
get discouraged. Most people with depression feel better with medication,
psychotherapy or both.
Depression care at Mayo Clinic
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SYMPTOMS
Although depression may occur only once during your life, people typically have
multiple episodes. During these episodes, symptoms occur most of the day, nearly
every day and may include:
* Feelings of sadness, tearfulness, emptiness or hopelessness
* Angry outbursts, irritability or frustration, even over small matters
* Loss of interest or pleasure in most or all normal activities, such as sex,
hobbies or sports
* Sleep disturbances, including insomnia or sleeping too much
* Tiredness and lack of energy, so even small tasks take extra effort
* Reduced appetite and weight loss or increased cravings for food and weight
gain
* Anxiety, agitation or restlessness
* Slowed thinking, speaking or body movements
* Feelings of worthlessness or guilt, fixating on past failures or self-blame
* Trouble thinking, concentrating, making decisions and remembering things
* Frequent or recurrent thoughts of death, suicidal thoughts, suicide attempts
or suicide
* Unexplained physical problems, such as back pain or headaches
For many people with depression, symptoms usually are severe enough to cause
noticeable problems in day-to-day activities, such as work, school, social
activities or relationships with others. Some people may feel generally
miserable or unhappy without really knowing why.
DEPRESSION SYMPTOMS IN CHILDREN AND TEENS
Common signs and symptoms of depression in children and teenagers are similar to
those of adults, but there can be some differences.
* In younger children, symptoms of depression may include sadness,
irritability, clinginess, worry, aches and pains, refusing to go to school,
or being underweight.
* In teens, symptoms may include sadness, irritability, feeling negative and
worthless, anger, poor performance or poor attendance at school, feeling
misunderstood and extremely sensitive, using recreational drugs or alcohol,
eating or sleeping too much, self-harm, loss of interest in normal
activities, and avoidance of social interaction.
DEPRESSION SYMPTOMS IN OLDER ADULTS
Depression is not a normal part of growing older, and it should never be taken
lightly. Unfortunately, depression often goes undiagnosed and untreated in older
adults, and they may feel reluctant to seek help. Symptoms of depression may be
different or less obvious in older adults, such as:
* Memory difficulties or personality changes
* Physical aches or pain
* Fatigue, loss of appetite, sleep problems or loss of interest in sex — not
caused by a medical condition or medication
* Often wanting to stay at home, rather than going out to socialize or doing
new things
* Suicidal thinking or feelings, especially in older men
WHEN TO SEE A DOCTOR
If you feel depressed, make an appointment to see your doctor or mental health
professional as soon as you can. If you're reluctant to seek treatment, talk to
a friend or loved one, any health care professional, a faith leader, or someone
else you trust.
WHEN TO GET EMERGENCY HELP
If you think you may hurt yourself or attempt suicide, call 911 in the U.S. or
your local emergency number immediately.
Also consider these options if you're having suicidal thoughts:
* Call your doctor or mental health professional.
* Contact a suicide hotline.
* In the U.S., call or text 988 to reach the 988 Suicide & Crisis Lifeline,
available 24 hours a day, seven days a week. Or use the Lifeline Chat.
Services are free and confidential.
* U.S. veterans or service members who are in crisis can call 988 and then
press “1” for the Veterans Crisis Line. Or text 838255. Or chat online.
* The Suicide & Crisis Lifeline in the U.S. has a Spanish language phone
line at 1-888-628-9454 (toll-free).
* Reach out to a close friend or loved one.
* Contact a minister, spiritual leader or someone else in your faith community.
If you have a loved one who is in danger of suicide or has made a suicide
attempt, make sure someone stays with that person. Call 911 or your local
emergency number immediately. Or, if you think you can do so safely, take the
person to the nearest hospital emergency room.
MORE INFORMATION
* Depression (major depressive disorder) care at Mayo Clinic
* Male depression: Understanding the issues
* Nervous breakdown: What does it mean?
* Pain and depression: Is there a link?
Show more related information
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CAUSES
It's not known exactly what causes depression. As with many mental disorders, a
variety of factors may be involved, such as:
* Biological differences. People with depression appear to have physical
changes in their brains. The significance of these changes is still
uncertain, but may eventually help pinpoint causes.
* Brain chemistry. Neurotransmitters are naturally occurring brain chemicals
that likely play a role in depression. Recent research indicates that changes
in the function and effect of these neurotransmitters and how they interact
with neurocircuits involved in maintaining mood stability may play a
significant role in depression and its treatment.
* Hormones. Changes in the body's balance of hormones may be involved in
causing or triggering depression. Hormone changes can result with pregnancy
and during the weeks or months after delivery (postpartum) and from thyroid
problems, menopause or a number of other conditions.
* Inherited traits. Depression is more common in people whose blood relatives
also have this condition. Researchers are trying to find genes that may be
involved in causing depression.
MORE INFORMATION
* Depression (major depressive disorder) care at Mayo Clinic
* Marijuana and depression
* Vitamin B-12 and depression
RISK FACTORS
Depression often begins in the teens, 20s or 30s, but it can happen at any age.
More women than men are diagnosed with depression, but this may be due in part
because women are more likely to seek treatment.
Factors that seem to increase the risk of developing or triggering depression
include:
* Certain personality traits, such as low self-esteem and being too dependent,
self-critical or pessimistic
* Traumatic or stressful events, such as physical or sexual abuse, the death or
loss of a loved one, a difficult relationship, or financial problems
* Blood relatives with a history of depression, bipolar disorder, alcoholism or
suicide
* Being lesbian, gay, bisexual or transgender, or having variations in the
development of genital organs that aren't clearly male or female (intersex)
in an unsupportive situation
* History of other mental health disorders, such as anxiety disorder, eating
disorders or post-traumatic stress disorder
* Abuse of alcohol or recreational drugs
* Serious or chronic illness, including cancer, stroke, chronic pain or heart
disease
* Certain medications, such as some high blood pressure medications or sleeping
pills (talk to your doctor before stopping any medication)
COMPLICATIONS
Depression is a serious disorder that can take a terrible toll on you and your
family. Depression often gets worse if it isn't treated, resulting in emotional,
behavioral and health problems that affect every area of your life.
Examples of complications associated with depression include:
* Excess weight or obesity, which can lead to heart disease and diabetes
* Pain or physical illness
* Alcohol or drug misuse
* Anxiety, panic disorder or social phobia
* Family conflicts, relationship difficulties, and work or school problems
* Social isolation
* Suicidal feelings, suicide attempts or suicide
* Self-mutilation, such as cutting
* Premature death from medical conditions
MORE INFORMATION
* Depression (major depressive disorder) care at Mayo Clinic
* Depression and anxiety: Can I have both?
PREVENTION
There's no sure way to prevent depression. However, these strategies may help.
* Take steps to control stress, to increase your resilience and boost your
self-esteem.
* Reach out to family and friends, especially in times of crisis, to help you
weather rough spells.
* Get treatment at the earliest sign of a problem to help prevent depression
from worsening.
* Consider getting long-term maintenance treatment to help prevent a relapse of
symptoms.
By Mayo Clinic Staff
Depression (major depressive disorder) care at Mayo Clinic
Request an appointment
Diagnosis & treatment
Oct. 14, 2022
Print
Show references
1. Brown AY. Allscripts EPSi. Mayo Clinic, Rochester, Minn. Nov. 17, 2016.
2. Research report: Psychiatry and psychology, 2016-2017. Mayo Clinic.
http://www.mayo.edu/research/departments-divisions/department-psychiatry-psychology/overview?_ga=1.199925222.939187614.1464371889.
Accessed Jan. 23, 2017.
3. Depressive disorders. In: Diagnostic and Statistical Manual of Mental
Disorders DSM-5. 5th ed. Arlington, Va.: American Psychiatric Association;
2013. http://www.psychiatryonline.org. Accessed Jan. 23, 2017.
4. Depression. National Institute of Mental Health.
https://www.nimh.nih.gov/health/topics/depression/index.shtml. Accessed
Jan. 23, 2017.
5. Depression. National Alliance on Mental Illness.
http://www.nami.org/Learn-More/Mental-Health-Conditions/Depression/Overview.
Accessed Jan. 23, 2017.
6. Depression: What you need to know. National Institute of Mental Health.
https://www.nimh.nih.gov/health/publications/depression-what-you-need-to-know/index.shtml.
Accessed Jan. 23, 2017.
7. What is depression? American Psychiatric Association.
https://www.psychiatry.org/patients-families/depression/what-is-depression.
Accessed Jan. 23, 2017.
8. Depression. NIH Senior Health.
https://nihseniorhealth.gov/depression/aboutdepression/01.html. Accessed
Jan. 23, 2017.
9. Children’s mental health: Anxiety and depression. Centers for Disease
Control and Prevention.
https://www.cdc.gov/childrensmentalhealth/depression.html#depression.
Accessed. Jan. 23, 2017.
10. Depression and complementary health approaches: What the science says.
National Center for Complementary and Integrative Health.
https://nccih.nih.gov/health/providers/digest/depression-science. Accessed
Jan. 23, 2017.
11. Depression. Natural Medicines.
https://naturalmedicines.therapeuticresearch.com/databases/medical-conditions/d/depression.aspx.
Accessed Jan. 23, 2017.
12. Natural medicines in the clinical management of depression. Natural
Medicines.
http://naturaldatabase.therapeuticresearch.com/ce/CECourse.aspx?cs=naturalstandard&s=ND&pm=5&pc=15-111.
Accessed Jan. 23, 2017.
13. The road to resilience. American Psychological Association.
http://www.apa.org/helpcenter/road-resilience.aspx. Accessed Jan. 23, 2017.
14. Simon G, et al. Unipolar depression in adults: Choosing initial treatment.
http://www.uptodate.com/home. Accessed Jan. 23, 2017.
15. Stewart D, et al. Risks of antidepressants during pregnancy: Selective
serotonin reuptake inhibitors (SSRIs). http://www.uptodate.com/home.
Accessed Jan. 23, 2017.
16. Kimmel MC, et al. Safety of infant exposure to antidepressants and
benzodiazepines through breastfeeding. http://www.uptodate.com/home.
Accessed Jan. 23, 2017.
17. Bipolar and related disorders. In: Diagnostic and Statistical Manual of
Mental Disorders DSM-5. 5th ed. Arlington, Va.: American Psychiatric
Association; 2013. http://www.psychiatryonline.org. Accessed Jan. 23, 2017.
18. Hirsch M, et al. Monoamine oxidase inhibitors (MAOIs) for treating
depressed adults. http://www.uptodate.com/home. Accessed Jan. 24, 2017.
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