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Text Content
* * Register | * Login * Home * News * Features * Podcasts * Research * White Papers & Webcasts * Events * Biotechnology * Genetics * Pathology * Reproductive Health * Medical Devices & Imaging * Pediatrics * Toggle navigation LifeSciencesIntelligence * Home * News * Features * Interviews * Podcasts * White Papers & Webcasts * Events * * Login * Register | * Biotechnology * Genetics & Genomics * Pathology * Reproductive Health * Medical Devices & Imaging * Pediatrics TopicBiotechnologyGenetics & GenomicsPathologyReproductive HealthMedical Devices & ImagingPediatrics PATHOLOGY NEWS EARLY DEPRESSION DIAGNOSIS LINKED TO HIGHER RATE OF DEMENTIA JAMA STUDY LINKS DEPRESSION DIAGNOSIS IN EARLY AND MIDDLE LIFE TO HIGHER RATES OF DEMENTIA, WITH A STRONGER LINK IN MEN. Source: Getty Images Share on Twitter By Veronica Salib July 25, 2023 - A recent study published in JAMA Neurology on July 24, 2023, linked depression diagnoses to dementia diagnoses later in life. Researchers’ analysis revealed that early- and middle-life depression diagnoses correlated with a higher risk of dementia later in life. The study focused on a cohort of Danish patients, collecting data from April 2022 to March 2023. Researchers evaluated data from participants between 1977 and 2018 using the Danish National Patient Registry (DNPR) and the Danish Psychiatric Central Research Register (DPCRR). The study used data from 246,499 individuals with depression and 1,190,302 without depression. The majority of patients with depression were diagnosed before the age of 60. DIG DEEPER * Understanding the Link Between Psychological Distress and Dementia * USPSTF Updates Depression, Suicide, Anxiety Screening Recommendations * Long-Term Exposure to Air Pollutants Linked to Depression and Anxiety According to the study, across all patients, those with depression were 2.41 times more likely to be diagnosed with dementia later in life than those without depression. A depression diagnosis early in life, between 18 and 44, was associated with the highest risk of dementia later in life, with a 3.08 times greater probability compared to those who did not have a depression diagnosis. Meanwhile, a depression diagnosis in middle life —ages 45 to 59 — was linked to a 2.95 times greater probability of dementia. The final age bracket, which had a depression diagnosis starting at age 60 or older, had a 2.31 times greater risk of dementia than their counterparts without depression. While the dementia rate was higher for anyone with a depression diagnosis, regardless of age, the risk was significantly higher for those diagnosed with depression earlier in life. Beyond analyzing risk by age, the researchers also evaluated the impact of gender, finding that men with depression were at a higher risk for dementia than women with depression, with a hazard ratio of 2.95 and 2.31, respectively. “Results suggest that the risk of dementia was more than doubled for both men and women with diagnosed depression. The persistent association between dementia and depression diagnosed in early and middle life suggests that depression may increase dementia risk,” concluded researchers in the study. Although the insights from this study provide potential hypotheses on the link between mental health and dementia, additional clinical research on a broader patient population is necessary for definitive conclusions. * Tagged * American Medical Association * Dementia * Depression * Mental Healthcare * Neuroscience Share on Twitter SIGN UP TO RECEIVE OUR NEWSLETTER AND ACCESS OUR RESOURCES Enjoy this article as well as all of our content, including E-Guides, news, tips and more. * You forgot to provide an Email Address. This email address doesn’t appear to be valid. Please provide a Corporate Email Address. This email address is already registered. Please log in. You have exceeded the maximum character limit. * * I agree to TechTarget’s Terms of Use, Privacy Policy, and the transfer of my information to the United States for processing to provide me with relevant information as described in our Privacy Policy. 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RELATED ARTICLES * PTSD Is Associated with Accelerated Cognitive Decline * Understanding the Link Between Psychological Distress and Dementia * Understanding the Multifaceted Aspects of Dementia, Its Stages, Subtypes RELATED RESOURCES * Industry Report: Virtual Value: A Market Survey on The Shift to Digital Scientific Discourse in Pharma and Biotech * America's Amphetamine Problem, Beyond the Pharmaceutical Supply Chain Newsletter Signup Sign up to receive our newsletter and access our resources * Life Sciences and MedTech News * Bio and Pharma News * Healthcare Exec Roundup * Pharma/BioMed * Life Sciences * You forgot to provide an Email Address. This email address doesn’t appear to be valid. Please provide a Corporate Email Address. This email address is already registered. Please log in. 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Recent Articles * Exercise Program Improves Pediatric Cardiometabolic Health * Comparing Stryker and Medtronic’s 2022 ESG Ratings * ctDNA Testing Reduces Time to Treatment for Lung Cancer Patients * Early Depression Diagnosis Linked to Higher Rate of Dementia Popular Topics * Public Health * Medical Research * CDC * Chronic Disease Management * Infectious Disease * Reproductive Health * Pediatric Healthcare * FDA * Access to Care * Interviews NEXT IN PATHOLOGY Consuming Omega-3 Fatty Acids Maintains Lung Health NIH Study Reveals * About Us * Contact Us * Advertise on LifeSciencesIntelligence * Privacy Policy * DMCA Policy * Terms & Conditions * Sitemap * EHRIntelligence * HealthITSecurity * HealthITAnalytics * RevCycleIntelligence * mHealthIntelligence * HealthPayerIntelligence * HITInfrastructure * PatientEngagementHIT * PharmaNewsIntelligence * HealthCareExecIntelligence Do Not Sell or Share My Personal Information | Cookie Preferences ©2012-2023 TechTarget, Inc. 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