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URL: https://pblab.tau.ac.il/
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PABLO BLINDER LAB

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Proper brain function relays on constant distribution of nutrients and oxygen to
active regions. During the course of evolution, different brain organs – such as
the cortex, the cerebellum and others – acquired highly specified morphologies
with exquisitely different neuronal and glial networks. Despite these
differences, increase in neuronal network activity results in a localized
vascular response. The differences in the sign and amplitude of the vascular
response, the triggering physiological factor as well as the key cellular
players in this interface have sparked a vivid debate in the literature. We seek
to understand the nature of this interface while carefully quantifying its
structure and function, both at the system and micro-circuit levels.