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 1. Medicines
 2. Analgesics and Pain Medication


DEXKETOPROFEN FOR PAIN KERAL

Last updated by Michael Stewart Peer reviewed by Sid Dajani
Last updated 19 Jan 2023 Meets Patient’s editorial guidelines



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Dexketoprofen is a painkiller. It is called a non-steroidal anti-inflammatory
drug. It is also known as an 'NSAID'.

The usual dose is either half a 25 mg tablet every 4-6 hours, or one 25 mg
tablet every eight hours. Your doctor will tell you which dose is right for you.

Pain relief is more rapid if dexketoprofen is taken when your stomach is empty -
this means taking the tablets about 30 minutes before food.



IN THIS ARTICLE

 * About dexketoprofen
 * Before taking dexketoprofen
 * How to take dexketoprofen
 * Getting the most from your treatment
 * Can dexketoprofen cause problems?
 * How to store dexketoprofen
 * Important information about all medicines

In This Article

DEXKETOPROFEN FOR PAIN

KERAL

IN THIS ARTICLE

 * About dexketoprofen
 * Before taking dexketoprofen
 * How to take dexketoprofen
 * Getting the most from your treatment
 * Can dexketoprofen cause problems?
 * How to store dexketoprofen
 * Important information about all medicines


ABOUT DEXKETOPROFEN

Type of medicineA non-steroidal anti-inflammatory drug (NSAID)Used forShort-term
painful conditionsAlso calledKeral®;
Skudexa® (dexketoprofen with tramadol)Available asTablets

Anti-inflammatory painkillers like dexketoprofen are also called non-steroidal
anti-inflammatory drugs (NSAIDs), or sometimes just 'anti-inflammatories'.
Dexketoprofen is used to treat short-term painful conditions such as muscular
sprains and strains, period (menstrual) pain, and toothache.

Dexketoprofen works by blocking the effect of natural chemicals called
cyclo-oxygenase (COX) enzymes. These enzymes help to make other chemicals in the
body, called prostaglandins. Some prostaglandins are produced at sites of injury
or damage, and cause pain and inflammation. By blocking the effect of COX
enzymes, fewer prostaglandins are produced, which means the pain is eased.




BEFORE TAKING DEXKETOPROFEN

Some medicines are not suitable for people with certain conditions, and
sometimes a medicine can only be used if extra care is taken. For these reasons,
before you start taking dexketoprofen, it is important that your doctor knows:

 * If you have ever had a stomach or duodenal ulcer, or if you have an
   inflammatory bowel disorder such as Crohn's disease or ulcerative colitis.
 * If you have asthma or any other allergic disorder.
 * If you are pregnant, trying for a baby, or breastfeeding.
 * If you have any problems with the way your liver works, or if you have any
   problems with the way your kidneys work.
 * If you have a heart condition or a problem with your blood vessels or
   circulation.
 * If you have high blood pressure.
 * If you have any blood clotting problems.
 * If you have high blood sugar or cholesterol levels.
 * If you have a connective tissue disorder such as systemic lupus
   erythematosus. This is an inflammatory condition which is also called lupus
   or SLE.
 * If you are taking any other medicines. This includes any medicines you are
   taking which are available to buy without a prescription, as well as herbal
   and complementary medicines.
 * If you have ever had an allergic reaction to any other NSAID (such as
   aspirin, ibuprofen, diclofenac, and indometacin), or to any other medicine.




HOW TO TAKE DEXKETOPROFEN

 * Before you start taking dexketoprofen, read the manufacturer's printed
   information leaflet from inside the pack. It will give you more information
   about the tablets and will provide you a full list of the side-effects which
   you could experience from taking them.
 * Your doctor will tell you how many tablets to take and how often to take
   them, but this will be no more three 25 mg tablets in total each day.
   Depending upon your condition, you will be asked to take either half a 25 mg
   tablet every 4-6 hours, or one 25 mg tablet every eight hours. You will be
   given a short course of treatment - you can stop taking the tablets once the
   painfulness has gone.
 * Take the tablets with a drink of water. They work more quickly if you take
   them when your stomach is empty, so ideally they should be taken about 30
   minutes before food. However, if taking the tablets makes you feel queasy
   then you will be better taking your doses after food as this will help to
   reduce any feelings of sickness.
 * If you forget to take a dose, take it as soon as you remember unless your
   next dose is due. If your next dose is due then take the dose which is due
   but leave out the forgotten one. Do not take two doses together to make up
   for a missed dose.




GETTING THE MOST FROM YOUR TREATMENT

 * Your doctor will prescribe you the lowest effective dose of dexketoprofen for
   the shortest time. This is to reduce the risk of side-effects. Take the
   tablets exactly as your doctor tells you to.
 * Try to keep any follow-up appointments with your doctor. This is so your
   doctor can check on your progress.
 * If you have asthma, symptoms such as wheeze or breathlessness can be made
   worse by dexketoprofen. If this happens to you, you should stop taking the
   tablets and see your doctor as soon as possible.
 * If you buy any medicines, check with a pharmacist that they are suitable for
   you to take. This is because you should not take dexketoprofen with any other
   anti-inflammatory painkiller, some of which are available in cold and flu
   remedies which can be bought 'over the counter'.
 * If you are having an operation or dental treatment, tell the person carrying
   out the treatment which medicines you are taking.


CAN DEXKETOPROFEN CAUSE PROBLEMS?

Along with their useful effects, most medicines can cause unwanted side-effects
although not everyone experiences them. The table below contains some of the
more common ones associated with dexketoprofen. The best place to find a full
list of the side-effects which can be associated with your medicine, is from the
manufacturer's printed information leaflet supplied with the medicine.
Alternatively, you can find an example of a manufacturer's information leaflet
in the reference section below. Speak with your doctor or pharmacist if any of
the following continue or become troublesome.

Common dexketoprofen side-effects (these affect fewer than 1 in 10 people)What
can I do if I experience this?Indigestion, heartburn, tummy (abdominal)
discomfortIf troublesome, speak with your doctorFeeling sick (nausea) or being
sick (vomiting), diarrhoeaDrink plenty of liquid to replace any lost fluids. Try
taking the tablets after meals

Important: if you experience any of the following rare but possibly serious
symptoms, stop taking dexketoprofen and contact your doctor for advice
straightaway:

 * If you have any breathing difficulties such as wheeze or breathlessness.
 * If you have any signs of an allergic reaction such as swelling around your
   mouth or face, or an itchy skin rash.
 * If you pass blood or black stools, bring up (vomit) blood, or have severe
   stomach pains.

If you experience any other symptoms which you think may be due to the medicine,
speak with your doctor or pharmacist for further advice.


HOW TO STORE DEXKETOPROFEN

 * Keep all medicines out of the reach and sight of children.
 * Store in a cool, dry place, away from direct heat and light.


IMPORTANT INFORMATION ABOUT ALL MEDICINES

Never take more than the prescribed dose. If you suspect that you or someone
else might have taken an overdose of this medicine, go to the accident and
emergency department of your local hospital. Take the container with you, even
if it is empty.

This medicine is for you. Never give it to other people even if their condition
appears to be the same as yours.

Do not keep out-of-date or unwanted medicines. Take them to your local pharmacy
which will dispose of them for you.

If you have any questions about this medicine ask your pharmacist.



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FURTHER READING AND REFERENCES

 * Manufacturer’s PIL, Keral® 25 mg tablets; A. Menarini Farmaceutica
   Internazionale SRL, The electronic Medicines Compendium. Dated June 2022.

 * Medicines Complete BNF 86th Edition; British Medical Association and Royal
   Pharmaceutical Society of Great Britain, London.





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> hi everyonehas anyone tried meloxicam 7.5mg for osteoarthritis pain ? i have
> it in alot of my joints all over my body .are the side effects bad on this
> medication as i am extremely sensitive to so...
> 
> Princessjanes

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ARTICLE INFORMATION

 * Last updated by Michael Stewart
 * Peer reviewed by Sid Dajani
 * Document ID 3689 (v27)
 * Last updated on 19 January 2023
 * Next review date 18 January 2026

The information on this page is written and peer reviewed by qualified
clinicians.

Disclaimer: This article is for information only and should not be used for the
diagnosis or treatment of medical conditions. Egton Medical Information Systems
Limited has used all reasonable care in compiling the information but make no
warranty as to its accuracy. Consult a doctor or other health care professional
for diagnosis and treatment of medical conditions. For details see our
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