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Thursday, Feb 24th 2022 7PM 4°C 10PM 3°C 5-Day Forecast
Advertisement
MORE EVIDENCE COVID WAS TINKERED WITH IN A LAB? NOW SCIENTISTS FIND VIRUS
CONTAINS TINY CHUNK OF DNA THAT MATCHES SEQUENCE PATENTED BY MODERNA THREE YEARS
BEFORE PANDEMIC BEGAN
* Genetic match discovered in Covid's unique furin cleavage site on spike
protein
* Matched genetic sequence patented by Moderna for cancer research purposes
* Researchers say one in 3trillion chance Covid developed the code naturally
By Connor Boyd Deputy Health Editor For Mailonline
Published: 17:48 GMT, 23 February 2022 | Updated: 08:55 GMT, 24 February 2022
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Fresh suspicion that Covid may have been tinkered with in a lab emerged today
after scientists found genetic material owned by Moderna in the virus's spike
protein.
They identified a tiny snippet of code that is identical to part of a gene
patented by the vaccine maker three years before the pandemic.
It was discovered in SARS-CoV-2's unique furin cleavage site, the part that
makes it so good at infecting people and separates it from other coronaviruses.
The structure has been one of the focal points of debate about the virus's
origin, with some scientists claiming it could not have been acquired
naturally.
The international team of researchers suggest the virus may have mutated to have
a furin cleavage site during experiments on human cells in a lab.
They claim there is a one-in-three-trillion chance Moderna's sequence randomly
appeared through natural evolution.
But there is some debate about whether the match is as rare as the study claims,
with other experts describing it as a 'quirky' coincidence rather than a
'smoking gun'.
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SARS-CoV-2, which causes Covid, carries all the information needed for it to
spread in around 30,000 letters of genetic code, known as RNA. The virus shares
a sequence of 19 specific letters with a genetic section owned by
Moderna. Twelve of the shared letters make up the structure of Covid's furin
cleavage site, with the rest being a match with nucleotides on a nearby part of
the genome
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Moderna filed the patent in February 2016 as part of its cancer research
division, records show. The patented sequence is part of a gene called MSH3 that
is known to affect how damaged cells repair themselves in the body. It was
approved on March 7 the following year
In the latest study, published in Frontiers in Virology, researchers compared
Covid's makeup to millions of sequenced proteins on an online database.
The virus is made up of 30,000 letters of genetic code that carry the
information it needs to spread, known as nucleotides.
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It is the only coronavirus of its type to carry 12 unique letters that allow its
spike protein to be activated by a common enzyme called furin, allowing it to
spread between human cells with ease.
Analysis of the original Covid genome found the virus shares a sequence of 19
specific letters with a genetic section owned by Moderna, which has a total of
3,300 nucleotides.
WHAT IS THE FURIN CLEAVAGE SITE?
SARS-CoV-2, which causes Covid, carries all the information needed for it to
spread in around 30,000 letters of genetic code, known as RNA.
But it is the only coronavirus of its type to carry 12 unique letters that allow
it to be activated by a common enzyme called furin.
This in turn makes the virus better at invading neighbouring cells.
The so-called furin cleavage site is located on the virus' spike protein, the
structure that binds to human cells in the first place.
Scientists sometimes add this element to lab viruses to make them more
infectious, but in nature, pathogens can acquire it by swapping genetic code
with other members of their family.
The furin has been the focal point of intrigue for many scientists studying the
origins of the virus because no other known member of Covid's family - a group
called Sarbecoviruses - have the site.
Advertisement
The US-based pharmaceutical firm filed the patent in February 2016 as part of
its cancer research division, records show.
The patented sequence is part of a gene called MSH3 that is known to affect how
damaged cells repair themselves in the body.
Scientists have highlighted this pathway as a potential target for new cancer
treatments.
Twelve of the shared letters make up the structure of Covid's furin cleavage
site, with the rest being a match with nucleotides on a nearby part of the
genome.
Writing in the paper, led by Dr Balamurali Ambati, from the University of
Oregon, the researchers said the matching code may have originally been
introduced to the Covid genome through infected human cells expressing the MSH3
gene.
Professor Lawrence Young, a virologist at Warwick University, admitted the
latest finding was interesting but claimed it was not significant enough to
suggest lab manipulation.
He told MailOnline: 'We're talking about a very, very, very small piece made up
of 19 nucleotides.
'So it doesn't mean very much to be frank, if you do these types of searches you
can always find matches.
'Sometimes these things happen fortuitously, sometimes it's the result of
convergent evolution (when organisms evolve independently to have similar traits
to adapt to their environment).
'It's a quirky observation but I wouldn't call it a smoking gun because it's too
small.
He added: 'It doesn't get us any further with the debate about whether Covid was
engineered.'
Dr Simon Clarke, a microbiologist at Reading University, questioned whether the
find was as rare as the study claims.
He told MailOnline: 'There can only be a certain number of [genetic combinations
within] furin cleavage sites.
'They function like a lock and key in the cell, and the two only fit together in
a limited number of combinations.
'So it's an interesting coincidence but this is surely entirely coincidental.'
MailOnline has approached Moderna for comment.
Circumstantial evidence has long raised questions about the origin of Covid and
its link to the Wuhan Institute of Virology.
The facility was known to be conducting experiments on bat coronavirus strains
similar to the one responsible for the pandemic.
China insisted early and often that the virus did not leak from the lab,
claiming that crossover to humans must have occurred at a 'wet market' in Wuhan
that sold live animals.
Perhaps driven by animosity for then-US President Donald Trump, who embraced the
lab leak theory early on, mainstream media and academics in the West heaped
scorn on the possibility, calling it an unhinged conspiracy theory.
But leaked emails showed that top scientists advising the UK and US Governments
expressed concerns about the official narrative privately.
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A study earlier this month found traces of Covid samples that contained
genetical material from humans, hamsters and monkeys and may have predated the
official pandemic timeline.
Sir Jeremy Farrar, an eminent British expert who publicly denounced the theory
as a 'conspiracy', admitted in a private email in February 2020 that a 'likely
explanation' was that the virus was man-made.
The then-UK Government adviser said at the time he was '70:30 or 60:40' in
favour of an accidental release versus natural origin.
In the email, sent to American health chiefs Dr Anthony Fauci and Dr Francis
Collins, Sir Jeremy said it was possible Covid had been evolved from a Sars-like
virus in the lab.
He went on that this seemingly benign process may have 'accidentally created a
virus primed for rapid transmission between humans'.
But the British scientist was shut down by his counterparts in the US who warned
further debate about the origins of the virus could damage 'international
harmony'.
In the latest twist, a study earlier this month found traces of Covid samples
that contained genetical material from humans, hamsters and monkeys and may have
predated the official pandemic timeline.
CHINA'S OFFICIAL PANDEMIC TIMELINE OF THE CORONAVIRUS PANDEMIC AND THE EVIDENCE
THAT UNDERMINES IT
Official timeline
Dec 8, 2019 - Earliest date that China has acknowledged an infection
Dec 31 - China first reported 'pneumonia of unknown cause' to the World Health
Organisation
Jan 1, 2020 - Wuhan seafood market closed for disinfection
Jan 7 - President Xi Jinping discusses coronavirus outbreak with his politburo
Jan 9 - China makes public the genome of the coronavirus
Jan 11 - China reported its first death
Jan 13 - First case outside China is confirmed
Jan 20 - China's National Health Commission confirms human-to-human
transmission
Jan 23 - Wuhan locked down
Jan 31 - WHO declared 'outbreak of international concern' as China admitted
having thousands of cases
Feb 23 - Italy reports cluster of cases in first major outbreak in the West
May 29 - China claims virus did not originate in wet markets but in Chinese bats
before it jumped to humans via an 'intermediary animal'
July 31 - Chinese researcher admits some coronavirus experiments conducted in
lower biosafety labs
Dec 16 - WHO announces it will travel to Wuhan to probe origins of virus in
January
Jan 5, 2021 - China denies entry to WHO's investigatory team
Feb 9 - WHO dismisses theory virus leaked from lab - backs China's claim it was
imported from frozen meat
Mar 28 - Former US national security officials says intel shows 'there was a
direct order from Beijing to destroy all viral samples' at Wuhan lab
New evidence
2012: Six miners struck down with with a mysterious flu-like illness in Mojiang
cave in Yunnan.
They were found to have been infected with the closest known relative to Covid,
sharing 97% of its genes.
Samples RATG13 are sent to the Wuhan Institute of Virology to be studied.
Sep 2019- Blood samples are taken in a lung cancer screening trial in Italy
which later test positive for coronavirus
Oct - Whistleblower Wei Jingsheng claims China deliberately spread Covid at The
World Military Games in Wuhan in October, two months before the rest of the
world knew about the virus
Oct - Xi Jinping's authoritarian regime tried desperately to shut down
whistle-blowers like Mr Jingsheng. Any references made in social media about a
new SARS virus or 'outbreak' were censored
Oct-Dec - Rise in 'flu and pneumonia' cases in northern Italy which could be
linked to coronavirus
Nov - Whistleblower Mr Jingsheng claims he took his concerns about the military
games to senior figures within the Trump administration but was ignored
Nov - Intelligence report passed to agencies in Washington claims three members
of staff at the Wuhan Institute of Virology sought hospital treatment in
November 2019 after experiencing symptoms consistent with Covid
Nov - Sewage samples taken in Florianópolis, Brazil, suggest virus was present
Nov 10 - Milanese woman has a skin biopsy, producing a sample which later shows
signs of the virus
Nov 17 - Leaked documents suggest case detected in China on this date
Dec - Doctors in China, including Li Wenliang, report existance of new type of
respiratory infection. But Chinese police arrested him and eight of his
colleagues for questioning - instead of publicising reports and warning public
Dec 1 - Chinese researchers report an infection on this date in a peer-reviewed
study, but it has not been acknowledged by Beijing
Dec 18 - Sewage samples taken in Milan and Turin suggest virus was circulating
in the cities
Dec 26 - Samples analysed suggested a new type of SARS was circulating as early
as December 26, but Wuhan was not locked down until January 22
Jan 2020 - Sewage samples from Barcelona suggest virus was in the city
Jan 3 - Covid-19 infections begin sweeping across other nations including the
U.S. as the WHO labelled the outbreak a Public Health Emergency of International
Concern
May - Scientists at a government lab in California concluded that Covid-19 may
have escaped from a facility in Wuhan
July - WHO chief Tedros Adhanom Ghebreyesus said China failed share vital raw
data during their investigation in Wuhan. China rebuffed those claims
June 2021: Leading US virus expert Dr Anthony Fauci was warned Covid may have
been engineered in a lab, emails publicly released reveal.
August: The world's first Covid-19 patient may have been infected by a bat while
working for a Wuhan lab in China, WHO chief Dr Peter Embarek said
August: A damning report by Republicans in the US claims coronavirus leaked from
the Wuhan Institute of Virology, shortly after the facility tried to improve air
safety and waste treatment systems
The report also cited 'ample evidence' that lab scientists were working to
modify coronaviruses to infect humans and such manipulation could be hidden.
October: US intelligence review into origins of pandemic does not reach a
judgement on whether the virus emerged via animal-to-human transmission or a lab
leak.
Chinese officials branded the report 'political and false'.
January 2022: Leaked emails from top UK scientist Sir Jeremy Farrar showed he
admitted in February 2020 that it was a 'likely explanation' that the virus
could be man-made. But he went on to brand the theory a 'conspiracy'.
February: Sir Farrar is called to be interviewed under oath at the US Congress.
Officials want him to explain why he shifted away from the lab leak theory.
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Read more:
* Frontiers | MSH3 Homology and Potential Recombination Link to SARS-CoV-2
Furin Cleavage Site | Virology
SHARE OR COMMENT ON THIS ARTICLE:
FRESH LAB LEAK FEARS AS STUDY FINDS GENETIC CODE IN COVID'S SPIKE PROTEIN LINKED
TO MODERNA PATENT
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* Shanna Moakler, 46, and on-again boyfriend Matthew Rondeau, 29, pile on PDA
in San Diego... after reality TV star was booted from Celebrity Big Brother
* Willow Smith, 21, holds hands with her musician beau De'Wayne, 26, as they
stock up on groceries at Whole Foods in Malibu
* Katharine McPhee wishes her and David Foster's son Rennie a happy first
birthday as she shares snaps from the baby's party: 'Where does the time go?'
* Mandy Moore gets glam in all-black for Jimmy Kimmel Live appearance after
making an eye-catching arrival in a multicoloured striped dress
* Idris Elba set to grace the cover of the latest issue of T Australia T
Australia has launched their first issue of 2022 with the Luther actor as
their cover star.
* Real Housewives Of New Jersey: Teresa Giudice storms off to protect 'love of
my life' Luis Ruelas Drama
* Poppy Delevingne and Victoria Beckham arrive at Longleat as Vogue editor
Edward Enninful gets set to marry his long-term partner Alec Maxwell
* He's still got it! Hugh Jackman, 53, shows off his rippling abs as he jumps
into freezing water
* Ayesha Curry rocks black bikini while sipping champagne on a family vacation
with husband Stephen Curry and their three-year-old son Canon in Mexico
* Vicky Pattison, 34, is engaged! TV personality set to wed boyfriend Ercan
Ramadan, 28, as he proposes during Dubai holiday and she flashes her £200K
ring
* Emma Raducanu RETIRES with a hip in the final set of marathon first outing
since her shock second-round Australian Open exit... after three hours and 36
minutes
* James Argent gets back on track after breaking his silence on a 'very bad
relapse' as he rocks Rolling Stones emblem jacket for fashion launch bash
* Oscars are cutting EIGHT CATEGORIES from the live broadcast in an attempt to
rebound from all-time low ratings... angering fans on Twitter
* Lindsay Lohan reveals how to correctly pronounce her name in a brief TikTok
video
* Rust armorer Hannah Gutierrez-Reed steps out in Arizona after she's named in
lawsuit filed by the family of slain cinematographer Halyna Hutchins
* Tinashe shows off her cleavage and bold fashion sense in a low-cut corset top
and fur-trimmed coat while stopping by Jimmy Kimmel Live
* Sam Hunt's pregnant wife Hannah Lee Fowler withdraws divorce petition on the
same day as filing... after accusing country musician of infidelity
* Leonardo DiCaprio buys equity stake in 100-year-old green-friendly champagne
house Telmont New venture for the 47-year-old Oscar-winning actor
* Michael Buble's wife Luisana showcases bump for first time in his new music
video for I'll Never Not Love You as couple prepare for baby number four
* Nicole Scherzinger puts on a busty display in a tiny hot pink bikini as she
enjoys a margarita on the beach in Mexico
* Ciara strikes a seductive pose in a pair of skintight denim and black pants
and a sheer bodysuit for latest shoot
* Beauty Awards 2022: Amber Gill puts on a busty display in a purple corset
while AJ Adudu turns heads in a orange minidress as they lead the glamour
* Beauty Awards 2022: Pregnant Olivia Bowen cradles her blossoming baby bump in
figure-hugging black feathered dress as she poses with husband Alex
* Beauty Awards 2022: Dancing On Ice's Liberty Poole flaunts her ample cleavage
in a leather khaki dress as she walks the black carpet
* Lisa Rinna's daughter Amelia Hamlin rocks grungy leather coat as she struts
around Milan during Fashion Week
* Malin Andersson announces her newborn daughter's name is Xaya and reveals she
had an emergency caesarean as she shares first snap
* 'I felt so embarrassed': Rosie O'Donnell says sorry to Priyanka Chopra and
Nick Jonas after mistakenly thinking Priyanka's father was Deepak Chopra
* Kym Marsh catches the eye in red leather trousers for Fatal Attraction play
press night ahead of starring as Alex Forrest in the production
* Pioneer Woman Ree Drummond shares sweet snap twinning with her mother Gerre
Schwert as they sip cocktails they made for her show
* Emily Maitlis quit BBC role because she was 'frustrated' at being
'ticked-off' by bosses over impartiality, source says
* Kylie Jenner and Travis Scott's newborn son Wolf's full name revealed on
birth certificate... and his middle name has family connection
* Addison Rae is set to star in new film Fashionista for Paramount Players...
after the success of Netflix's He's All That
* Kim Kardashian pays tribute to late father Robert Kardashian on what would
have been his 78th birthday with throwback snap from 1998
* Whitney Port reflects on her IVF 'rollercoaster' as she basks in the sunshine
in her black bathing suit: 'It's just so crazy'
* Below Deck Sailing Yacht stars reveal the WORST thing about filming the hit
reality series: 'It was torture'
* Bethenny Frankel shares vacation photos with daughter Bryn Hoppy, 11, in
Costa Rica: 'I'll never grow out of the mommy & me phase'
* John Mulaney is bundled up in a tan coat as he heads to Saturday Night Live
rehearsal ahead of hosting gig in NYC
* Russell Brand cuts a vibrant figure in a tie-dye cardigan as he heads out to
dinner in Manchester during break from comedy tour
* Jeff Garlin is seen for the first time since exiting The Goldbergs after HR
investigation into inappropriate conduct claims
* Molly-Mae Hague shows off her new short hairstyle as she steps out in windy
Cheshire after debuting look on Instagram
* Gisele Bundchen shows off statuesque legs and taut tummy as she continues to
enjoy her vacation in Costa Rica
* Nick Cannon celebrates his son Golden's fifth birthday with fun-filled Black
Panther themed bash: 'Golden turned 5 in Wakanda today!'
* Foo Fighters frontman Dave Grohl brands himself 'f***ing deaf' as he
discusses hearing loss and confesses he's been 'reading lips for like 20
YEARS'
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revealed... as rapper readies Donda 2 concert in Miami
* EDEN CONFIDENTIAL: Catwalk Spencers put their family first at London Fashion
Week
* Married At First Sight's Selina Chhaur parades her incredible figure in a
high-waisted bikini as she hits the beach for a solo swim in Adelaide
* Neighbours veterans Ian Smith and Anne Charleston reunite for a rare TV
interview as the Aussie soap faces the axe after Channel 5 pulled funding
* Fern Britton ends 13-year feud with Phillip Schofield as she congratulates
him on 40th television anniversary with heartfelt video message
* Kim Kardashian pokes fun at her MANY engagements as family celebrates her
sister Kourtney Kardashian and Travis Barker after proposal in new trailer
* Artem Chigvintsev set to return to Dancing With the Stars live tour after
month long battle with pneumonia
* Halle Berry keeps a low profile in a patterned headscarf as she steps out
grocery shopping in Los Angeles
* Simon Cowell responds to the 'heart breaking' passing of America's Got Talent
contestant Nightbirde after cancer battle
* Bryce Dallas Howard celebrates 21 years since 'first date' with husband Seth
Gabel by sharing tender snaps: 'Over two decades of being in love'
* Alan Titchmarsh brands modern TV dramas an 'unremitting diet of tragedy and
despair'... and says he prefers Emily in Paris instead
* Giggling Kate whizzes down the slide instead of taking the stairs at the Lego
Foundation Play Lab as she dons £59.99 Zara blazer in Denmark
* Married At First Sight's Olivia Frazer reveals the VERY strict rules
contestants had to follow during filming: 'We all had cabin fever'
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born in resurfaced interview before his tragic death
* Evan Rachel Wood expands on claims Marilyn Manson sexually abused her and
details activism on behalf of survivors in Phoenix Rising trailer
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after fertility struggle: 'It took him five years to get here'
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to reschedule live shows after he falls ill with Chickenpox
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emerges and one groom is flung across the table in wild trailer
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Kenneth Branagh will also star in Christopher Nolan's biopic
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'having a boob job' on the company dime and 'abusing role as CEO'
* Today's headlines
* Most Read
* Russia troops attacking CHERNOBYL could set off radiation cloud across
Europe, Ukraine warns as bomb hits...
* Ukraine strikes back: Kiev's troops have already shot down five Russian
helicopters, destroyed dozens of...
* More than 150 senior Russian officials sign open letter condemning Putin's
invasion of Ukraine as 'an...
* White House deputy press secretary calls Trump a 'nauseating, fearful pig'
who with Putin is 'rubbing their...
* 'Peace on our continent has been shattered': NATO orders its commanders to
prepare to defend allied...
* How Putin rains down death on Ukraine: The thermonuclear-capable Kalibr
cruise missile Russia is using to...
* Putin's innocent victims: Bloodied Ukrainians stagger through rubble and weep
beside slaughtered loved-ones...
* DAN WOOTTON: God help us that senile old men Putin and Biden hold world peace
in their hands. Boris should...
* US and Western allies are poised to hit Russia with crippling second phase
sanctions hitting banks, exports...
* Prepare for BLITZKRIEG in Ukraine: Military expert predicts Putin's next move
will be to drive tanks deep...
* Why has Putin invaded Ukraine and how will it affect YOU? How 'despot' with
dreams of recreating the Soviet...
* Putin cuts off vital shipping route to Ukraine while his forces move on Kiev:
Russian vessels blockade the...
* 'Take Chelsea FC from Roman Abramovich': Commons is shown bombshell leaked
documents accusing billionaire of...
* Mother who slowly starved her 24-year-old Down's Syndrome daughter to death
in filthy bedroom covered in...
* How will Putin attack the West? Online banks and mobile phone reception will
CUT OUT, nations will be hit by...
* Brace for thundersnow, blizzards AND flooding: Temperatures dip to -2C with
snow as far south as Devon as...
* Family doctor, 54, is accused of giving a woman a cup of tea laced with his
semen - after victim discovered...
* Army corporal, 30, who sexually assaulted junior male soldier in Germany by
performing sex act on him while...
* Bees explosively EJACULATE to death during heatwaves, with a phallus the size
of their abdomen bursting from...
* Case against lawyer, 37, accused of injecting food with his blood at Tesco,
Sainsbury's and Waitrose...
* Six people are taken to hospital in eight-car pileup on the M5 causing
traffic chaos as air ambulance lands...
* PM freezes assets of ALL Russia's banks, bans them from City and vows to
limit how much cash oligarchs can...
* Hollywood to the rescue: Actor Sean Penn sits in front row of Ukrainian
government press briefing after...
* Ukrainians in UK make desperate calls to loved ones back home... but hear
NOTHING as phone lines and...
* Biden joins G7 leaders condemning Putin for 're-introducing war' to Europe
and being on the 'wrong side of...
* Will China bail out Putin? Fears Beijing could take on the West by stepping
in to buy Russian gas and oil...
* Putin cracks down on Russians who call for PEACE in Ukraine: Demonstrators in
Moscow are dragged away by...
* Tory MPs accuse Boris Johnson of ENCOURAGING invasion of Ukraine with
'pathetic' sanctions that 'Putin...
* President George Bush says Putin's attack is the 'gravest' threat to Europe
since World War Two and...
* How the Ukraine invasion unfolded minute-by-minute: Russian shells rain down
on Mariupol at 3.30am, Putin...
* Escape Kiev: Petrol stations start rationing fuel as desperate Ukrainians
attempt to flee capital while huge...
* 'Where's sleepy Joe?' Biden is slammed for not making an on camera address
since Tuesday despite Russia's...
* 'If Russia puts a bootstep into Nato territory we're ALL at war': Retired
General warns Britain's 'children...
* Gary Lineker deletes Ukraine crisis tweet after facing fierce backlash for
saying 'trillions spent on a...
* Did Putin record his chilling threat to NUKE the west three days ago -
proving he had no intention for...
* World turns on 'madman' Putin as minister urges Russian generals to stage a
COUP and end 'illogical'...
* Reservist soldier vows to 'stay and fight' to protect his country and
students pack their cars so they can...
* Brave Ukrainian mum reveals she's leaving her kids behind to fight against
Russian invasion - as she issues...
* War unfolds before their eyes: Videos recorded by Ukrainians show cruise
missiles flying overhead, Russian...
* Putin's terrifying warning to the West: 'To anyone who would consider
interfering from the outside - if you...
* British banks brace for Russian cyber attacks: Lloyds boss says business is
on 'heightened alert' over fears...
* US brings firepower to Latvia: First contingent of 800 American troops
arrives at Russia's doorstep in the...
* How war will drive the cost of living crisis : Inflation could hit 8.2% in
months as Ukraine invasion sends...
* 'This is what happens when America's enemies see a weak and incompetent
President': Scores of Republicans...
* Woman, 29, and her partner left with chemical burns and damaged eyesight
after they were sprayed with...
* Dogs grieve the death of a loved one too: Pups show key signs of mourning
after a canine companion passes...
* MPs tell GPs face-to-face appointments are their 'essential mission' now
Covid restrictions are axed - as...
* Met Police officer, 28, is CLEARED of raping woman at five-star London hotel
after prosecutors dropped the...
* Toys' R' Us RETURNS: Stalwart will make a comeback to Britain's High Streets
'within months' - four years...
* Fury over Dorset council 'hypocrisy' after officials ordered four protected
trees to be chopped down to make...
* MORE HEADLINES
* Russia troops attacking CHERNOBYL could set off radiation cloud across
Europe, Ukraine warns as bomb hits ship owned by NATO-member Turkey in Black
Sea and Kiev sends citizens to shelters ahead of 'imminent' bombing
* Putin's terrifying warning to the West: 'To anyone who would consider
interfering from the outside - if you do, you will face consequences greater
than any you have faced in history' as he claims he is 'de-Nazifying'
Ukraine
* Chelsea's billionaire owner Roman Abramovich 'has been effectively BARRED
from living in Britain'... as he is named as one of the 'key enablers' of
Vladimir Putin's regime
* 'If Russia puts a bootstep into Nato territory we're ALL at war': Retired
General warns Britain's 'children and grandchildren' will be called to fight
if Putin advances across Europe
* Boris warns the West MUST stand up to 'dictator' Putin after he 'unleashed
war' on Ukraine: PM rings NATO allies as he vows to 'hobble' the Russian
economy with 'massive' sanctions package being unveiled tonight
* James Bulger killer Jon Venables 'will launch a new bid for freedom within
weeks' after serving five years behind bars for vile child pornography hoard
* Escape Kiev: Petrol stations start rationing fuel as desperate Ukrainians
attempt to flee capital while huge queues form around ATMs as people try to
withdraw savings
* Pressure goes on the Queen to strip expat Prince Harry of his 'Counsellor of
State' role but MPs are told disgraced Andrew should be STILL allowed to
stand in for the monarch if she is incapacitated
* More evidence Covid was tinkered with in a lab? Now scientists find virus
contains tiny chunk of DNA that matches sequence patented by Moderna THREE
YEARS before pandemic began
* Putin's innocent victims: Bloodied Ukrainians stagger through rubble and weep
beside slaughtered loved-ones in shocking images from Kharkiv city bombed
overnight… after Vladimir declared war to 'protect civilians'
* More than 150 senior Russian officials sign open letter condemning Putin's
invasion of Ukraine as 'an unprecedented atrocity' and warn of 'catastrophic
consequences' while urging citizens 'not to participate'
* War in prime time: Networks scramble to cover Putin's Ukraine invasion and
break into programming. War correspondents don helmets and flak jackets as
missiles strike
* Defiant Ukrainians answer president's call to arms as they clear out gun
shops of AK-47s and ammo after he warned Putin 'we are ready for everything,
we will win'
* VW dealership adviser, 34, who refused to wear face mask during the pandemic
because it caused her 'severe distress' was unfairly sacked, tribunal rules
* How the Ukraine invasion unfolded minute-by-minute: Russian shells rain down
on Mariupol at 3.30am, Putin declares war two hours later and then all hell
breaks loose across nation and capital Kiev
* 'Take Chelsea FC from Roman Abramovich': Commons is shown bombshell leaked
documents accusing billionaire of links to Russian corruption and paying for
political influence - as Labour demands his assets and £152m home are seized
* Did Putin record his chilling threat to NUKE the west three days ago -
proving he had no intention for peace? Dictator wore same suit and tie during
Monday's unhinged Ukrainian history lesson
* Ukraine strikes back: Kiev's troops have already shot down five Russian
helicopters, destroyed dozens of tanks and captured dozens of troops as
Putin's forces take heavy losses
* Will China bail out Putin? Fears Beijing could take on the West by stepping
in to buy Russian gas and oil and limit impact of financial sanctions
* Attack possible 'before the end of the night': US in stark new warning after
revealing Kremlin troops are 'ready to go NOW' as Putin's puppet leaders in
rebel border regions call for Moscow's 'help against Ukraine's aggression'
* Queen 'getting over' Covid: Monarch, 95, only has 'very mild' symptoms say
sources as she holds regular phone conversations with Boris Johnson
* Police interrupted No. 10 'party' after alarm went off: Scotland Yard
admission sparks questions over why officers did not intervene in Downing
Street Covid gathering
* Get ready for a thundersnow Thursday! Met Office issues yellow snow and
lightning warnings across parts of UK as Scotland braces for up to EIGHT
INCHES of the white stuff on higher ground
* 'It all happened because of a rigged election': Trump says Putin would NEVER
have invaded Ukraine if he was still president and says 'Sleepy Joe' Biden
'is in bed right now'
* A TENNER for fish and chips! Average price of British classic could top £10
due to soaring cost of cod and mushy peas
* War unfolds before their eyes: Videos recorded by Ukrainians show cruise
missiles flying overhead, Russian troops parachuting in and devastating
explosions around them
* Ed Sheeran and wife Cherry Seaborn 'lay flowers at mural for music mogul
Jamal Edwards' following his sudden death at age 31
* Husband of Rust cinematographer Halyna Hutchins says he felt 'so angry'
seeing Alec Baldwin describe killing her on set and then fail to 'accept any
responsibility'
* Biden now SANCTIONS Nord Stream 2's corporate officers: White House says $11
billion pipeline is 'dead at the bottom of the sea' and warns Putin or more
sanctions if he 'continues to escalate'
* Former public schoolboy, 21, hanged himself at his parents' home minutes
after he was dismissed over Zoom from his trainee business analyst job at
Deloitte two months into lockdown, inquest hears
* We will cripple Russian economy: Boris Johnson is set to urge the West to hit
Russian oligarchs and companies where it hurts if Vladimir Putin pushes on
with Ukraine invasion
* The Queen, 95, is 'on the road to recovery' from Covid but 'still a bit under
the weather' as she is monitored closely after cancelling engagements for
second time in 48 hours
* 'The world will hold Russia accountable': Biden condemns Putin's 'unprovoked
and unjustified attack' on Ukraine: Announces 'severe sanctions' and will
address the nation on crisis at midday
* Mother who slowly starved her 24-year-old Down's Syndrome daughter to death
in filthy bedroom covered in takeaway boxes and used nappies is jailed for
nearly 10 years
* Tory MPs accuse Boris Johnson of ENCOURAGING invasion of Ukraine with
'pathetic' sanctions that 'Putin doesn't give a sh*t about'
* EXCLUSIVE: Devastated fiancée of dive instructor mauled to death by a shark
breaks her silence saying she's the 'luckiest woman alive' to have met her
'soulmate' - as his family post an emotional tribute
* 'Olive' from On the Buses died in house fire 'started by cigarette':
Neighbours say star of 70s comedy and Eastenders Anna Karen, 85, was killed
in blaze after she fell asleep while smoking
* The Crown jewels have been stolen: Thieves swipe 200 gems and antiques worth
£150,000 from the set of hit Netflix drama, including a rare Fabergé egg
replica, after raiding three lorries
* Half of Russians believe it is RIGHT to use military force to keep Ukraine
out of NATO and a third back 'reuniting' the two countries, poll reveals
* Children's therapist who 'violently' slapped a vulnerable four-year-old boy
'10 to 20 times' because he didn't put his shoes on is ruled fit to work
again after 'addressing his failings' and 'reflecting' on the assault
* Brace for thundersnow, blizzards AND flooding: Temperatures dip to -2C with
snow as far south as Devon as cold snap grips the UK - with fears 'Storm
Gladys' could hit with 51 flood warnings still in place
* MOST READ IN DETAIL
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