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2600:1901:0:c831:: Public Scan

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Submitted URL:
https://www.pubmed.ncbi.nlm.nih.gov/36694514
Effective URL:
https://pubmed.ncbi.nlm.nih.gov/36694514/
Submission: On April 30 via manual (April 30th 2024, 5:25:43 pm UTC) from IN — Scanned from DE

Form analysis
10 forms found in the DOM

GET /

<form action="/" method="get" autocomplete="off" class="usa-search usa-search-big search-form content-page-layout" id="search-form" role="search">
  <div class="inner-wrap">
    <a class="pubmed-logo" aria-label="Pubmed Logo" href="/" data-ga-category="featured_link" data-ga-action="pubmed_logo">


        <img src="https://cdn.ncbi.nlm.nih.gov/pubmed/1a615b6f-2998-460a-b410-19e16cc12be7/core/images/pubmed-logo-blue.svg" alt="pubmed logo">
      
    </a>
    <a href="#" class="search-input-trigger" data-alt-title="Hide search bar" title="Show search bar" aria-label="Show search bar" aria-hidden="true" tabindex="-1">
    </a>
    <div role="search" class="search-input">
      <div class="form-field ">
        <label class="usa-sr-only" for="id_term"> Search: </label>
        <span class="twitter-typeahead ncbi-autocomplete"><input type="search" name="term" data-skip-ie-scroll-to-top="" data-replace-term-with-exact="" data-exact-query="" placeholder="" class="term-input tt-input" required="required" id="id_term"
            spellcheck="false" dir="auto" style="position: relative; vertical-align: top;" aria-owns="id_term_listbox" role="combobox" aria-autocomplete="list" aria-expanded="false"><span role="status" aria-live="polite"
            style="position: absolute; padding: 0px; border: 0px; height: 1px; width: 1px; margin-bottom: -1px; margin-right: -1px; overflow: hidden; clip: rect(0px, 0px, 0px, 0px); white-space: nowrap;"></span>
          <pre aria-hidden="true"
            style="position: absolute; visibility: hidden; white-space: pre; font-family: BlinkMacSystemFont, -apple-system, &quot;Segoe UI&quot;, Roboto, Oxygen, Ubuntu, Cantarell, &quot;Fira Sans&quot;, &quot;Droid Sans&quot;, &quot;Helvetica Neue&quot;, sans-serif; font-size: 16px; font-style: normal; font-variant: normal; font-weight: 400; word-spacing: 0px; letter-spacing: 0px; text-indent: 0px; text-rendering: auto; text-transform: none;"></pre>
          <div role="listbox" class="tt-menu" id="id_term_listbox" aria-expanded="false" style="position: absolute; top: 100%; left: 0px; z-index: 100; display: none;">
            <div role="presentation" class="tt-dataset tt-dataset-0"></div>
          </div>
        </span><a href="#" class="clear-btn" aria-label="Clear search input" title="Clear search input" role="button" data-pinger-ignore=""></a><button type="submit" class="search-btn" aria-label="Search" data-pinger-ignore=""><span
            class="usa-search-submit-text">Search</span></button>
      </div>
    </div>
    <!-- Create alert and Create RSS are buttons that look like links -->
    <!-- Better for them to look like buttons but no space -->
    <div class="search-links-wrapper content-page-layout">
      <div class="search-links">
        <a href="/advanced/" class="search-input-link adv-search-link" data-ga-category="featured_link" data-ga-action="adv_search">Advanced</a>
        <a href="/clipboard/" class="search-input-link clipboard-link hidden" data-ga-category="featured_link" data-ga-action="clipboard">
          Clipboard <span class="amount-in-clipboard"></span>
        </a>
      </div>
      <span class="search-input-link user-guide-link" role="navigation" aria-label="User guide">
        <a href="/help/" data-ga-category="featured_link" data-ga-action="user_guide">
            User Guide
          </a>
      </span>
    </div>
  </div>
</form>

POST /results-export-ids/

<form id="save-action-panel-form" class="action-panel-content action-form" action="/results-export-ids/" data-by-search-action="/results-export-search-data/" data-by-ids-action="/results-export-ids/" method="post" data-by-search-method="post"
  data-by-ids-method="post">
  <input type="hidden" name="csrfmiddlewaretoken" value="03HqKMNkReWZrcZqOdmiiY1hTKJpCcf4ZbKhNG9t9T6CyqW5R8sjvHKYwDGcijqd">
  <div class="action-panel-control-wrap">
    <label for="save-action-format" class="action-panel-label"> Format: </label>
    <select id="save-action-format" name="results-format" class="action-panel-selector">
      <option value="summary-text">Summary (text)</option>
      <option value="pubmed-text">PubMed</option>
      <option value="pmid">PMID</option>
      <option value="abstract">Abstract (text)</option>
      <option value="csv">CSV</option>
    </select>
  </div>
  <div class="action-panel-actions">
    <button class="action-panel-submit" type="submit" data-loading-label="Saving..." data-ga-category="save_share" data-ga-action="save" data-ga-label="save"> Create file </button>
    <button class="action-panel-cancel" aria-label="Close 'Save citations to file' panel" ref="linksrc=close_save_panel" aria-controls="save-action-panel" aria-expanded="false" data-ga-category="save_share" data-ga-action="save"
      data-ga-label="cancel"> Cancel </button>
  </div>
</form>

POST /send-email/

<form id="email-action-panel-form" class="action-panel-content action-form" action="/send-email/" data-by-search-action="/results-export-email-by-search-data/" data-by-ids-action="/send-email/" data-by-search-method="post" data-by-ids-method="post"
  method="post">
  <input type="hidden" name="csrfmiddlewaretoken" value="03HqKMNkReWZrcZqOdmiiY1hTKJpCcf4ZbKhNG9t9T6CyqW5R8sjvHKYwDGcijqd">
  <div class="action-panel-control-wrap">
    <span class="action-panel-label"> Subject: </span>
    <span class="email-subject" id="email-subject" aria-label="Email subject">1 selected item: 36694514 - PubMed</span>
    <input type="hidden" name="email-subject" value="1 selected item: 36694514">
    <input type="hidden" name="email-subject-hash" value="fa15b3abb3a443e805d8d20e44dd22dfeb4f7d47659900b6984e65422e6f61ea">
  </div>
  <div class="action-panel-control-wrap">
    <label for="email-to" class="action-panel-label required-field-asterisk"> To: </label>
    <input type="email" aria-label="Recipient Email Address" placeholder="email@example.com" id="email-to" class="email-to" pattern="^[a-zA-Z0-9_.+-]+@[a-zA-Z0-9-]+\.[a-zA-Z0-9-.]+$" maxlength="100" required="">
  </div>
  <div class="action-panel-control-wrap">
    <label for="email-from" class="action-panel-label"> From: </label>
    <input type="email" aria-label="Sender Email Address" placeholder="email@example.com" id="email-from" class="email-from" pattern="^[a-zA-Z0-9_.+-]+@[a-zA-Z0-9-]+\.[a-zA-Z0-9-.]+$" maxlength="256">
  </div>
  <div class="action-panel-control-wrap">
    <label for="email-citation-format" class="action-panel-label"> Format: </label>
    <select id="email-citation-format" name="citation-format" class="action-panel-selector email-citation-format">
      <option selected="selected" value="summary">Summary</option>
      <option value="summary-text">Summary (text)</option>
      <option value="abstract">Abstract</option>
      <option value="abstract-text">Abstract (text)</option>
    </select>
  </div>
  <div class="include-supplemental-container" style="display: none;">
    <input type="checkbox" aria-label="Include MeSH and other data" name="include-supplemental" id="email-include-supplemental" class="email-include-supplemental">
    <label for="email-include-supplemental" class="email-include-supplemental-label">MeSH and other data</label>
  </div>
  <div class="form-field recaptcha ">
    <div class="g-recaptcha" id="id-recaptcha" data-sitekey="6LfsWHMdAAAAAClKbtOpjQ2pMjgsGxvv7NdZW9uI"></div>
  </div>
  <div id="captcha-error-message" class="usa-input-error-message captcha-validation-message" role="alert"></div>
  <div class="action-panel-actions">
    <button class="action-panel-submit" type="submit" data-loading-label="Sending..." data-ga-category="save_share" data-ga-action="email" data-ga-label="send"> Send email </button>
    <button class="action-panel-cancel" aria-label="Close 'Email citations' panel" ref="linksrc=close_email_panel" aria-controls="email-action-panel" aria-expanded="false" data-ga-category="save_share" data-ga-action="email" data-ga-label="cancel">
      Cancel </button>
  </div>
  <input type="hidden" name="email-search-details" value="">
  <input type="hidden" name="email-search-details-hash" value="0e42663a6c3bd85498fcb88798998fed7bfdc45d457db35281e41afe13cc0524">
</form>

<form id="collections-action-panel-form" class="collections-action-panel-form action-panel-content action-form action-panel-smaller-selectors" data-existing-collections-url="/list-existing-collections/"
  data-add-to-existing-collection-url="/add-to-existing-collection/" data-create-and-add-to-new-collection-url="/create-and-add-to-new-collection/" data-get-article-ids-by-search-url="/get-article-ids-by-search/"
  data-myncbi-max-collection-name-length="100" data-add-to-collection-max-amount="1000" data-collections-root-url="https://www.ncbi.nlm.nih.gov/myncbi/collections/">
  <input type="hidden" name="csrfmiddlewaretoken" value="03HqKMNkReWZrcZqOdmiiY1hTKJpCcf4ZbKhNG9t9T6CyqW5R8sjvHKYwDGcijqd">
  <div class="choice-group" role="radiogroup">
    <ul class="radio-group-items">
      <li>
        <input type="radio" id="collections-action-panel-new" class="collections-new" name="collections" value="new" data-ga-category="save_share" data-ga-action="collections" data-ga-label="collections_radio_new">
        <label for="collections-action-panel-new">Create a new collection</label>
      </li>
      <li>
        <input type="radio" id="collections-action-panel-existing" class="collections-existing" name="collections" value="existing" checked="true" data-ga-category="save_share" data-ga-action="collections" data-ga-label="collections_radio_existing">
        <label for="collections-action-panel-existing">Add to an existing collection</label>
      </li>
    </ul>
  </div>
  <div class="controls-wrapper">
    <div class="action-panel-control-wrap new-collections-controls">
      <label for="collections-action-panel-add-to-new" class="action-panel-label required-field-asterisk"> Name your collection: </label>
      <input type="text" name="add-to-new-collection" id="collections-action-panel-add-to-new" class="collections-action-add-to-new" pattern="[^&quot;&amp;=<>\/]*" title="The following characters are not allowed in the Name field: &quot;&amp;=<>/"
        maxlength="100" data-ga-category="save_share" data-ga-action="create_collection" data-ga-label="non_favorties_collection">
      <div class="collections-new-name-too-long usa-input-error-message selection-validation-message"> Name must be less than 100 characters </div>
    </div>
    <div class="action-panel-control-wrap existing-collections-controls">
      <label for="collections-action-panel-add-to-existing" class="action-panel-label"> Choose a collection: </label>
      <select id="collections-action-panel-add-to-existing" class="action-panel-selector collections-action-add-to-existing" data-ga-category="save_share" data-ga-action="select_collection"
        data-ga-label="($('#collections-action-add-to-existing').val() === 'Favorites') ? 'Favorites' : 'non_favorites_collection'">
      </select>
      <div class="collections-retry-load-on-error usa-input-error-message selection-validation-message"> Unable to load your collection due to an error<br>
        <a href="#">Please try again</a>
      </div>
    </div>
  </div>
  <div class="action-panel-actions">
    <button class="action-panel-submit" type="submit" data-loading-label="Adding..." data-pinger-ignore="" data-ga-category="save_share" data-ga-action="collections" data-ga-label="add" disabled=""> Add </button>
    <button class="action-panel-cancel" aria-label="Close 'Add to Collections' panel" ref="linksrc=close_collections_panel" aria-controls="collections-action-panel" aria-expanded="false" data-ga-category="save_share" data-ga-action="collections"
      data-ga-label="cancel"> Cancel </button>
  </div>
</form>

<form id="bibliography-action-panel-form" class="bibliography-action-panel-form action-panel-content action-form action-panel-smaller-selectors" data-add-to-bibliography-max-amount="100" data-add-to-bibliography-batch-size="10"
  data-bibliography-delegates-url="/list-bibliography-delegates/" data-add-to-bibliography-url="/add-to-bibliography/" data-get-article-ids-by-search-url="/get-article-ids-by-search/"
  data-mybib-root-url="https://www.ncbi.nlm.nih.gov/myncbi/collections/mybibliography/">
  <input type="hidden" name="csrfmiddlewaretoken" value="03HqKMNkReWZrcZqOdmiiY1hTKJpCcf4ZbKhNG9t9T6CyqW5R8sjvHKYwDGcijqd">
  <div class="action-panel-control-wrap bibliographies-controls">
    <div class="choice-group">
      <ul class="bibliographies-action-add radio-group-items">
        <li>
          <input name="bibliography" id="my-bibliography" class="my-bibliography" type="radio" checked="">
          <label for="my-bibliography">My Bibliography</label>
        </li>
      </ul>
    </div>
  </div>
  <div class="bibliographies-retry-load-on-error usa-input-error-message selection-validation-message"> Unable to load your delegates due to an error<br>
    <a href="#">Please try again</a>
  </div>
  <div class="action-panel-actions">
    <button class="action-panel-submit" type="submit" data-loading-label="Adding..." data-pinger-ignore=""> Add </button>
    <button class="action-panel-cancel" aria-label="Close 'Add to bibliography' panel" ref="linksrc=close_bibliography_panel" aria-controls="bibliography-action-panel" aria-expanded="false" data-ga-category="save_share" data-ga-action="mybib"
      data-ga-label="cancel"> Cancel </button>
  </div>
</form>

<form id="saved-search-action-panel-form" class="saved-search-action-panel-form action-panel-content action-form" data-create-saved-search-url="/create-saved-search/" data-try-search-terms-url="/try-search-term/"
  data-saved-search-root-url="https://www.ncbi.nlm.nih.gov/myncbi/searches/">
  <input type="hidden" name="csrfmiddlewaretoken" value="03HqKMNkReWZrcZqOdmiiY1hTKJpCcf4ZbKhNG9t9T6CyqW5R8sjvHKYwDGcijqd">
  <div class="action-panel-control-wrap">
    <label for="saved-search-name" class="action-panel-label saved-search-name-label required-field-asterisk"> Name of saved search: </label>
    <input maxlength="200" type="text" name="saved-search-name" id="saved-search-name" class="saved-search-name" value="" required="" pattern="[^&quot;&amp;=<>\/]*" title="The following characters are not allowed in the Name field: &quot;&amp;=<>/">
  </div>
  <div class="action-panel-control-wrap">
    <label for="saved-search-term" class="action-panel-label required-field-asterisk"> Search terms: </label>
    <textarea name="saved-search-term" id="saved-search-term" class="saved-search-term" required=""></textarea>
  </div>
  <div class="test-search-term-wrap">
    <a href="#" class="try-search-term">Test search terms</a>
  </div>
  <div class="choice-group action-panel-extra-margin-top">
    <span class="action-panel-label" id="fieldset-label"> Would you like email updates of new search results? </span>
    <fieldset id="saved-search-alert" aria-describedby="fieldset-label">
      <legend class="usa-sr-only">Saved Search Alert Radio Buttons</legend>
      <ul class="radio-group-items">
        <li>
          <input type="radio" id="saved-search-alert-yes" class="saved-search-alert-yes" name="saved-search-alert" value="yes" checked="">
          <label for="saved-search-alert-yes" class="action-panel-label">Yes</label>
        </li>
        <li>
          <input aria-label="No radio input" type="radio" id="saved-search-alert-no" class="saved-search-alert-no" name="saved-search-alert" value="no">
          <label for="saved-search-alert-no" class="action-panel-label">No</label>
        </li>
      </ul>
    </fieldset>
  </div>
  <div class="alert-schedule-wrap">
    <div class="action-panel-control-wrap">
      <label class="action-panel-label"> Email: </label>
      <span aria-label="Email address" id="saved-search-email" class="action-panel-label"><span class="action-panel-label-bold"></span> (<a class="myncbi-account-settings" href="https://www.ncbi.nlm.nih.gov/account/settings/">change</a>)</span>
    </div>
    <div class="action-panel-control-wrap action-panel-extra-margin-top">
      <label for="saved-search-frequency" class="action-panel-label"> Frequency: </label>
      <select id="saved-search-frequency" class="no-border-panel-selector saved-search-frequency">
        <option value="monthly">Monthly</option>
        <option value="weekly">Weekly</option>
        <option value="daily">Daily</option>
      </select>
    </div>
    <div class="action-panel-control-wrap saved-search-monthly-additional">
      <label for="saved-search-monthly-on-day" class="action-panel-label"> Which day? </label>
      <select id="saved-search-monthly-on-day" class="no-border-panel-selector">
        <option value="Sunday">The first Sunday</option>
        <option value="Monday">The first Monday</option>
        <option value="Tuesday">The first Tuesday</option>
        <option value="Wednesday">The first Wednesday</option>
        <option value="Thursday">The first Thursday</option>
        <option value="Friday">The first Friday</option>
        <option value="Saturday">The first Saturday</option>
        <option value="day">The first day</option>
        <option value="weekday">The first weekday</option>
      </select>
    </div>
    <div class="action-panel-control-wrap saved-search-weekly-additional" style="display: none;">
      <label for="saved-search-weekly-on-day" class="action-panel-label"> Which day? </label>
      <select id="saved-search-weekly-on-day" class="no-border-panel-selector saved-search-weekly-on-day">
        <option value="Sunday">Sunday</option>
        <option value="Monday">Monday</option>
        <option value="Tuesday">Tuesday</option>
        <option value="Wednesday">Wednesday</option>
        <option value="Thursday">Thursday</option>
        <option value="Friday">Friday</option>
        <option value="Saturday">Saturday</option>
      </select>
    </div>
    <div class="action-panel-control-wrap">
      <label for="saved-search-report" class="action-panel-label"> Report format: </label>
      <select id="saved-search-report" class="no-border-panel-selector saved-search-report">
        <option value="DocSum">Summary</option>
        <option value="DocSumText">Summary (text)</option>
        <option value="Abstract">Abstract</option>
        <option value="AbstractText">Abstract (text)</option>
        <option value="MEDLINE">PubMed</option>
      </select>
    </div>
    <div class="action-panel-control-wrap">
      <label for="saved-search-amount" class="action-panel-label"> Send at most: </label>
      <select id="saved-search-amount" class="no-border-panel-selector saved-search-amount">
        <option value="1">1 item</option>
        <option value="5" selected="">5 items</option>
        <option value="10">10 items</option>
        <option value="20">20 items</option>
        <option value="50">50 items</option>
        <option value="100">100 items</option>
        <option value="200">200 items</option>
      </select>
    </div>
    <div>
      <input type="checkbox" id="saved-search-send-if-no-result" class="saved-search-send-if-no-result" name="saved-search-send-if-no-result">
      <label for="saved-search-send-if-no-result" class="action-panel-label smaller-checkbox"> Send even when there aren't any new results </label>
    </div>
    <div class="action-panel-control-wrap option-text-in-email-wrap">
      <label for="saved-search-email-text" class="action-panel-label"> Optional text in email: </label>
      <textarea name="saved-search-email-text" id="saved-search-email-text" class="saved-search-email-text"></textarea>
    </div>
  </div>
  <div class="action-panel-actions">
    <button class="action-panel-submit" type="submit" data-loading-label="Saving..." data-ga-category="save_share" data-ga-action="alert" data-ga-label="save"> Save </button>
    <button class="action-panel-cancel" aria-label="Close 'Your saved search' panel" ref="linksrc=close_saved_search_panel" aria-controls="saved-search-action-panel" aria-expanded="false" data-ga-category="save_share" data-ga-action="alert"
      data-ga-label="cancel"> Cancel </button>
  </div>
</form>

POST /results-export-ids/

<form id="citation-manager-action-panel-form" class="action-panel-content action-form" action="/results-export-ids/" data-by-search-action="/results-export-search-data/" data-by-ids-action="/results-export-ids/" method="post"
  data-by-search-method="post" data-by-ids-method="post">
  <input type="hidden" name="csrfmiddlewaretoken" value="03HqKMNkReWZrcZqOdmiiY1hTKJpCcf4ZbKhNG9t9T6CyqW5R8sjvHKYwDGcijqd">
  <input name="results-format" type="hidden" value="pubmed">
  <div class="action-panel-actions">
    <button class="action-panel-submit" type="submit" data-loading-label="Sending..." data-ga-category="save_share" data-ga-action="citation_manager" data-ga-label="save"> Create file </button>
    <button class="action-panel-cancel" aria-label="Close 'Send citations to citation manager' panel" ref="linksrc=close_citation_manager_panel" aria-controls="citation-manager-action-panel" aria-expanded="false" data-ga-category="save_share"
      data-ga-action="citation_manager" data-ga-label="cancel"> Cancel </button>
  </div>
</form>

<form id="rss-action-panel-form" class="rss-action-panel-form action-panel-content action-form" data-create-rss-feed-url="/create-rss-feed-url/" data-search-form-term-value="">
  <input type="hidden" name="csrfmiddlewaretoken" value="03HqKMNkReWZrcZqOdmiiY1hTKJpCcf4ZbKhNG9t9T6CyqW5R8sjvHKYwDGcijqd">
  <div class="action-panel-control-wrap">
    <label for="rss-name" class="action-panel-label required-field-asterisk"> Name of RSS Feed: </label>
    <input maxlength="200" placeholder="Name" type="text" name="rss-name" id="rss-name" class="rss-name" value="" required="" pattern="[^&quot;&amp;=<>\/]*" title="The following characters are not allowed in the Name field: &quot;&amp;=<>/">
  </div>
  <div class="rss-limit-wrap">
    <div class="action-panel-control-wrap action-panel-extra-margin-top">
      <label for="rss-limit" class="action-panel-label"> Number of items displayed: </label>
      <select id="rss-limit" class="no-border-panel-selector rss-limit">
        <option value="5">5</option>
        <option value="10">10</option>
        <option value="15" selected="selected">15</option>
        <option value="20">20</option>
        <option value="50">50</option>
        <option value="100">100</option>
      </select>
    </div>
  </div>
  <div class="action-panel-actions">
    <button class="action-panel-submit" type="submit" data-loading-label="Creating..." data-ga-category="save_share" data-ga-action="alert" data-ga-label="save"> Create RSS </button>
    <button class="action-panel-cancel" aria-label="Close 'Your RSS' panel" ref="linksrc=close_rss_panel" aria-controls="rss-action-panel" aria-expanded="false" data-ga-category="save_share" data-ga-action="alert" data-ga-label="cancel"> Cancel
    </button>
  </div>
  <div class="action-panel-control-wrap rss-link-copy-wrap">
    <label for="rss-link" class="usa-sr-only">RSS Link</label>
    <input placeholder="Your RSS Feed Link" type="text" name="rss-link" id="rss-link" class="rss-link" title="RSS Link">
    <button type="button" disabled="" class="rss-link-copy-button disabled" data-ga-category="save_share" data-ga-action="rss" data-ga-label="copy"> Copy </button>
  </div>
</form>

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Case Reports
Cureus
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. 2022 Dec 21;14(12):e32805.
doi: 10.7759/cureus.32805. eCollection 2022 Dec.


GIVING REST TO THE RESTLESS LEG: A CASE REPORT OF HOW SELF-EDUCATION PREPENDING
WEB-BASED INTERVENTIONS CAN AMELIORATE RESTLESS LEG SYNDROME

Qaisar Ali Khan  1 , Hoor Ul Ain  2 , Kavya Shah  3 , Karma Patel  4
, Christopher Farkouh  5 , Amba Swamy Naidu Pasupuleti  6 , Bhavana Vattikuti  7
, Vinay Suresh  8 , Natalia Santiago  9 , Matthew Farkouh  10
Affiliations Expand



AFFILIATIONS

 * 1 Internal Medicine, DHQ Teaching Hospital Kohat, Kohat, PAK.
 * 2 Internal Medicine, Jinnah Medical College, Peshawar, PAK.
 * 3 Medicine, Gujarat Medical Education and Research Society Medical College
   and Hospital, Himmat Nagar, IND.
 * 4 Medicine, Motilal Nehru Medical College and SRN Hospital, Prayagraj, IND.
 * 5 General Medicine, Rush Medical College, Chicago, USA.
 * 6 Medicine, MNR Medical College and Hospital, Sangareddy, IND.
 * 7 Internal Medicine, Cebu Doctors University College of Medicine,
   Philippines, PHL.
 * 8 General Medicine, King George's Medical University, Lucknow, IND.
 * 9 General Medicine, Universidad Autonoma de Guadalajara, Guadalajara, MEX.
 * 10 General Medicine, Ponce Health Sciences University, Ponce, USA.

 * PMID: 36694514
 * PMCID: PMC9860005
 * DOI: 10.7759/cureus.32805

Item in Clipboard
Case Reports


GIVING REST TO THE RESTLESS LEG: A CASE REPORT OF HOW SELF-EDUCATION PREPENDING
WEB-BASED INTERVENTIONS CAN AMELIORATE RESTLESS LEG SYNDROME

Qaisar Ali Khan et al. Cureus. 2022.
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Cureus
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. 2022 Dec 21;14(12):e32805.
doi: 10.7759/cureus.32805. eCollection 2022 Dec.


AUTHORS

Qaisar Ali Khan  1 , Hoor Ul Ain  2 , Kavya Shah  3 , Karma Patel  4
, Christopher Farkouh  5 , Amba Swamy Naidu Pasupuleti  6 , Bhavana Vattikuti  7
, Vinay Suresh  8 , Natalia Santiago  9 , Matthew Farkouh  10


AFFILIATIONS

 * 1 Internal Medicine, DHQ Teaching Hospital Kohat, Kohat, PAK.
 * 2 Internal Medicine, Jinnah Medical College, Peshawar, PAK.
 * 3 Medicine, Gujarat Medical Education and Research Society Medical College
   and Hospital, Himmat Nagar, IND.
 * 4 Medicine, Motilal Nehru Medical College and SRN Hospital, Prayagraj, IND.
 * 5 General Medicine, Rush Medical College, Chicago, USA.
 * 6 Medicine, MNR Medical College and Hospital, Sangareddy, IND.
 * 7 Internal Medicine, Cebu Doctors University College of Medicine,
   Philippines, PHL.
 * 8 General Medicine, King George's Medical University, Lucknow, IND.
 * 9 General Medicine, Universidad Autonoma de Guadalajara, Guadalajara, MEX.
 * 10 General Medicine, Ponce Health Sciences University, Ponce, USA.

 * PMID: 36694514
 * PMCID: PMC9860005
 * DOI: 10.7759/cureus.32805

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ABSTRACT

Restless leg syndrome (RLS) is a neurological disorder characterized by an
irresistible urge to move one's leg sporadically. The pathogenesis of RLS, also
known as Willis Ekborn disease, is not fully understood; however, scientists
note a complex interplay between multiple neuronal pathway-related genes with
endogenous and exogenous factors. We report a case of a previously healthy
27-year-old man complaining of a continuous urge to move his right leg, notably
at night. Laboratory evaluation proved negative for secondary causes of RLS;
hence the condition was labeled as "primary idiopathic." The patient was started
on appropriate pharmacotherapy and was advised to self-educate regarding his
ailment. The patient began internet-based self-education and displayed excellent
improvements on the International Restless Leg Syndrome Scale (IRLS). Mental
exercises, such as self-education using web-based intervention and
pharmacotherapy, could alleviate factors in patients with primary idiopathic
RLS. Further research is needed to clarify self-education's role in managing
RLS.

Keywords: amelioration; case report; restless leg syndrome; self- education;
web- based intervention.

Copyright © 2022, Ali Khan et al.

PubMed Disclaimer


CONFLICT OF INTEREST STATEMENT

The authors have declared that no competing interests exist.


FIGURES

Figure 1. The responses of the patient…

Figure 1. The responses of the patient to pharmacotherapy-only intervention on
the IRLS scale for…

Figure 1. The responses of the patient to pharmacotherapy-only intervention on
the IRLS scale for 12 months
IRLS: International Restless Leg Syndrome Scale

Figure 2. The responses of the patient…

Figure 2. The responses of the patient on the IRLS scale to pharmacotherapy in
addition…

Figure 2. The responses of the patient on the IRLS scale to pharmacotherapy in
addition to self-education at 8- and 16-week follow-up visits
IRLS: International Restless Leg Syndrome

See this image and copyright information in PMC



SIMILAR ARTICLES

 * Restless leg syndrome a common undiagnosed comorbidity of clinical
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   Rajender A, Mathur S, Choudhary P, Upadhyay S, Rajender G, Bhargava R,
   Nepalia S. Rajender A, et al. Gastroenterol Hepatol Bed Bench. 2019
   Winter;12(1):13-16. Gastroenterol Hepatol Bed Bench. 2019. PMID: 30949314
   Free PMC article.
 * [Diagnosis and symptom rating scale of restless legs syndrome].
   Inoue Y. Inoue Y. Brain Nerve. 2009 May;61(5):533-8. Brain Nerve. 2009. PMID:
   19514513 Review. Japanese.
 * Association between restless leg syndrom and slow coronary flow.
   Erden İ, Çakcak Erden E, Durmuş H, Tıbıllı H, Tabakçı M, Kalkan ME, Türker Y,
   Akçakoyun M. Erden İ, et al. Anadolu Kardiyol Derg. 2014 Nov;14(7):612-6.
   doi: 10.5152/akd.2014.5068. Epub 2014 Feb 14. Anadolu Kardiyol Derg. 2014.
   PMID: 25036324
 * Restless legs syndrome related to hemorrhage of a thoracic spinal cord
   cavernoma.
   Hamdaoui M, Ruppert E, Comtet H, Kilic-Huck U, Wolff V, Bataillard M, Bourgin
   P. Hamdaoui M, et al. J Spinal Cord Med. 2018 Mar;41(2):245-247. doi:
   10.1080/10790268.2017.1368963. Epub 2017 Sep 12. J Spinal Cord Med. 2018.
   PMID: 28899286 Free PMC article.
 * Differentiating nocturnal leg cramps and restless legs syndrome.
   Rana AQ, Khan F, Mosabbir A, Ondo W. Rana AQ, et al. Expert Rev Neurother.
   2014 Jul;14(7):813-8. doi: 10.1586/14737175.2014.927734. Epub 2014 Jun 14.
   Expert Rev Neurother. 2014. PMID: 24931546 Review.

See all similar articles


REFERENCES

 1. 1. Restless legs syndrome. Klingelhoefer L, Bhattacharya K, Reichmann H.
       Clin Med (Lond) 2016;16:379–382. - PMC - PubMed
 2. 1. Prevalence of restless legs syndrome and associated risk factors among
       middle-aged Saudi population. Wali SO, Abaalkhail B. Ann Thorac Med.
       2015;10:193–198. - PMC - PubMed
 3. 1. Restless legs syndrome associated with major diseases: a systematic
       review and new concept. Trenkwalder C, Allen R, Högl B, Paulus W,
       Winkelmann J. Neurology. 2016;86:1336–1343. - PMC - PubMed
 4. 1. Non-pharmacological interventions for restless legs syndrome: a
       systematic review of randomised controlled trials. Harrison EG, Keating
       JL, Morgan PE. Disabil Rehabil. 2019;41:2006–2014. - PubMed
 5. 1. Pharmacologic treatment of restless legs syndrome. Lv Q, Wang X, Asakawa
       T, Wang XP. Curr Neuropharmacol. 2021;19:372–382. - PMC - PubMed

Show all 11 references



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