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REVOLUTIONIZING DRUG DISCOVERY AT THE INTERSECTION OF SEMICONDUCTORS, LIVE-CELL
BIOLOGY AND MACHINE LEARNING




SEMICONDUCTOR-BIO MEASUREMENT AND MANIPULATION PLATFORM


BY PUTTING CONSUMER-GRADE CMOS CHIPS DIRECTLY INTO EACH WELL OF A CELL-CULTURE
MICROPLATE, WE ENABLE REAL-TIME, LIVE CELL ELECTROCHEMICAL IMAGING OF CELL
CULTURES AND NOVEL IN-VITRO SCREENS. SCREENING BIOLOGICAL PARAMETERS NEVER
BEFORE AVAILABLE, OPENING UP OPPORTUNITIES TO GENERATE A UNIQUE DRUG DISCOVERY
PIPELINE. QUANTIFYING MORPHOLOGICAL PARAMETERS LIKE ADHESION AND ATTACHMENT
WHICH HAVE DIRECT RELEVANCE TO INFLAMMATION AND CYSTIC DISEASES. MEASURING
METABOLIC STATE, APOPTOSIS/NECROSIS FOR CANCER APPLICATIONS AND ELECTRICAL
PARAMETERS FOR CARDIOVASCULAR OR NEUROLOGICAL DISEASES.

 * LABEL-FREE KINETICS
   The growth of the cell sheet can be measured to gather confluency over time
   
 * CELL MANIPULATION
   Create customized wound healing assays or form repeatable co-cultures
   
 * BARRIER FUNCTION
   Perform spatial TEER measurements to accurately assess cell-cell junction
   integrity
   
 * REDOX METABOLISM
   Visualize metabolic state of cells, investigate oxidative stress, antioxidant
   capacity, or mechanism of cell-death
   
 * ELECTROPHYSIOLOGY
   Measure & stimulate the electrical signals of excitable cells such as
   cardiomyocytes or neurons
   

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MULTI-PARAMETRIC

Combining cell kinetics, barrier function, metabolic state, electrophysiology
measurements and manipulations from the same cell culture

LIVE-CELL

Delivering non-invasive and label free measurements through the whole duration
of the assay – quality data extracted from living cells as they culture

HIGH-RESOLUTION

Generating optics-free images to understand what is happening down to a single
cell – overcome traditional whole-well aggregate readouts


CYTOTRONICS’ HIGH-DIMENSIONAL AND FUNCTIONAL ASSESSMENT OF LIVE-CELLS





NEWS AND PUBLICATIONS

 * CDL Computational Biology
   CDL is a non-profit organization with advisors and mentors assigned to
   massively-scalable, early-stage, technology-based companies.
   
   Learn more
   
 * Funding Announced (2022)
   CytoTronics Launches with $9.25 Million in Seed Funding to Revolutionize Drug
   Discovery and Phenotypic Screening.
   
   Learn more
   
 * Lab on a Chip (2022)
   Multi-parametric functional imaging of cell cultures and tissues with a CMOS
   microelectrode array.
   
   Learn more
   
 * Nature Biomedical Engineering (2020)
   A nanoelectrode array for obtaining intracellular recordings from thousands
   of connected neurons.
   
   Learn more
   
 * IEEE Journal of Solid-State Circuits (2020)
   CMOS nanoelectrode array for intracellular recording and stimulation of
   mammalian neurons.
   
   Learn more
   
 * Nature Nanotech (2017)
   CMOS nanoelectrode array for all-electrical intracellular
   electrophysiological imaging.
   
   Learn more
   

PreviousNext


OUR TEAM


CYTOTRONICS IS A TECH-BIO STARTUP SPUN OUT FROM A MULTI-DISCIPLINARY RESEARCH
PROJECT FROM THREE LABS AT HARVARD UNIVERSITY SPANNING SEMICONDUCTOR DESIGN,
CHEMISTRY AND SYSTEMS BIOLOGY.


WE ARE BUILDING A DRUG DISCOVERY ENGINE BASED ON A PLATFORM TECHNOLOGY THAT USES
A PROPRIETARY SEMICONDUCTOR-BIO INTERFACE TO GENERATE UNIQUE CELL-BIOLOGY
INFORMATION.


OUR PLATFORM ALLOWS US TO SCREEN PARAMETERS THAT WERE IMPOSSIBLE BEFORE, OPENING
UP OPPORTUNITIES TO GENERATE A UNIQUE DRUG DISCOVERY PIPELINE.

OPERATING TEAM
BOARD OF DIRECTORS
ADVISORS
OPERATING TEAM


JEFFREY ABBOTT, PHD

Co-founder & CEO
LinkedIn Profile
Jeffrey Abbott, PhD
Co-founder & CEO


ALEXANDER ALEXEYEV

Head of Electrical Engineering
LinkedIn Profile
Alexander Alexeyev
Head of Electrical Engineering


ZACH BOYNTON

ASIC Design Engineer
LinkedIn Profile
Zach Boynton, PhD
ASIC Design Engineer


MICKEY CHEAH

Senior ASIC Design Engineer
LinkedIn Profile
Mickey Cheah
Senior ASIC Design Engineer


SHALAKA CHITALE, PHD

Senior Scientist
LinkedIn Profile
Shalaka Chitale, PhD
Director, Biology


LORI CIRELLA

Finance Manager
Lori Cirella
Finance Manager


MICHELE GIOVENELLI

CFO
LinkedIn Profile
Michele Giovenelli
CFO


BERT LANNON, PHD

Snr Biologist & Data Scientist
LinkedIn Profile
Bert Lannon, PhD
Snr Biologist & Data Scientist


HENDRICK MELO

VP of Software Development
LinkedIn Profile
Hendrick Melo
VP, Software Development


ISHAN NAG

Snr Research Associate
LinkedIn Profile
Ishan Nag
Snr Research Associate


BRENDAN POWERS

Principal Software Engineer
LinkedIn Profile
Brendan Powers
Principal Software Engineer


DUANE SWORD

Co-founder & CBO
LinkedIn Profile
Duane Sword
Co-founder & CBO


HOLLIN WILKINS

Principal Cloud Software Engineer
LinkedIn Profile
Hollin Wilkins
Principal Cloud Software Engineer


VINCE WU, PHD

Co-founder & CTO
LinkedIn Profile
Vince Wu, PhD
Co-founder & CTO


BOARD OF DIRECTORS


JEFFREY ABBOTT, PHD

Co-founder & CEO
LinkedIn Profile
Jeffrey Abbott, PhD
Co-founder & CEO


JENNA ABELLI

Principal, Anzu Partners
LinkedIn Profile
Jenna Abelli
Principal, Anzu Partners


DOUGLAS KAHN

Executive Chariman, CytoTronics Former CEO & Chairman, TetraGenetics (acquired
by AbCellera)
LinkedIn Profile
Douglas Kahn
Executive Chariman, CytoTronics Former CEO & Chairman, TetraGenetics (acquired
by AbCellera)


TAYO SANDERS, PHD

Investor, Anzu Partners
LinkedIn Profile
Tayo Sanders, PhD
Director, SR Venture Studio


DUANE SWORD

Co-founder & CBO
LinkedIn Profile
Duane Sword
Co-founder & CBO


VINCE WU, PHD

Co-founder & CTO
LinkedIn Profile
Vince Wu, PhD
Co-founder & CTO


ADVISORS


SCIENTIFIC CO-FOUNDERS


DONHEE HAM, PHD

Harvard Professor of Electrical Engineering & Applied Physics
View Profile
Donhee Ham, PhD
Harvard Professor of Electrical Engineering & Applied Physics


HONGKUN PARK, PHD

Harvard Professor of Physics & Chemistry
LinkedIn Profile
Hongkun Park, PhD
Harvard Professor of Physics & Chemistry



ADVISORS


MILAD ALUCOZAI

Head of Bio and Deep Tech, BoxOne Ventures
LinkedIn Profile
Milad Alucozai
Head of Bio and Deep Tech, BoxOne Ventures


CHRIS BROWN, PHD

Co-founder and CTO, 908 Devices
LinkedIn Profile
Chris Brown, PhD
Co-founder and CTO, 908 Devices


WILLIAM CANTLEY, PHD

Senior Scientist, CNS Biology, Alnylam Pharmaceuticals
LinkedIn Profile
William Cantley, PhD
Senior Scientist, CNS Biology, Alnylam Pharmaceuticals


MIKE CUCCARESE, PHD

Director Translational Oncology, Recursion
LinkedIn Profile
Mike Cuccarese, PhD
Director Translational Oncology, Recursion


KEITH JAMES, PHD

Retired – former SVP Drug Discovery Insitro, prior roles with Ferring
Pharmaceuticals and Pfizer
LinkedIn Profile
Keith James, PhD
Retired – former SVP Drug Discovery Insitro, prior roles with Ferring
Pharmaceuticals and Pfizer


LINCOLN MUIR

Retired – former ACEA Biosciences (Agilent Technologies) Director
LinkedIn Profile
Lincoln Muir
Retired – former ACEA Biosciences (Agilent Technologies) Director


VLADISLAV ZARAYSKIY, PHD

Monte Rosa Therapeutics
LinkedIn Profile
Vladislav Zarayskiy, PhD
Monte Rosa Therapeutics



COLLABORATORS


AVIK MUKHERJEE, PHD

Postdoctoral Researcher, Harvard Medical School
LinkedIn Profile
Avik Mukherjee, PhD
Postdoctoral Researcher, Harvard Medical School


MARKUS BASAN, PHD

Assistant Professor, Harvard Medical School
LinkedIn Profile
Markus Basan, PhD
Assistant Professor, Harvard Medical School




CAREERS


CURRENT OPENINGS

Senior Biologist


RESUME DROP FOR FUTURE OPPORTUNITIES


DON’T SEE YOUR PERFECT ROLE, BUT INTERESTED IN DEVELOPING A BREAKTHROUGH
TECHNOLOGY TARGETING IMMEDIATE DRUG DISCOVERY APPLICATIONS? WE DON’T WANT TO LET
A JOB DESCRIPTION STOP YOU FROM APPLYING AND ARE ALWAYS LOOKING FOR HIGH
PERFORMERS TO JOIN OUR TEAM.

SHARE RESUME
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