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Effective URL: https://www.foundationmedicineasia.com/
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Effective URL: https://www.foundationmedicineasia.com/
Submission: On February 25 via api from US — Scanned from US
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FOR HEALTHCARE PROFESSIONALS ONLY
This website is a global information resource. It is intended for healthcare
professionals only outside of the United States of America (US) who are
interested in information on Foundation Medicine®. This site is not intended to
provide medical advice and/or treatment guidance. If you are a US healthcare
professional click here.
This site is produced by Roche as a partner of Roche Foundation Medicine.
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* Precision Medicine
* What is Precision Medicine?
* Comprehensive genomic profiling
* Our services
* Our portfolio
* FoundationOne® CDx
* FoundationOne® Liquid
* FoundationOne® Heme
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LIKE EVERY PERSON, EVERY TUMOUR IS UNIQUE.
OUR HIGH-QUALITY PORTFOLIO OF COMPREHENSIVE GENOMIC PROFILING SERVICES PROVIDES
POWERFUL INSIGHTS TO HELP OPTIMISE AND PERSONALISE TREATMENT STRATEGIES FOR
PATIENTS IN DIVERSE CLINICAL SITUATIONS.1–10
A COMPREHENSIVE APPROACH TO GENOMIC PROFILING
The Foundation Medicine comprehensive genomic profiling approach broadly
analyses the tumour genome to identify clinically relevant alterations and
potentially expand patients’ treatment options.*1–5 Clinicians then receive a
clear, in-depth report that supports clinical decision-making by providing
insights on the patient’s genomic profile as well as associated targeted
therapies, immunotherapies and relevant clinical trials.11
Learn more
A HIGH-QUALITY PORTFOLIO OF SERVICES
Our high-quality portfolio of services helps optimise and personalise treatment
strategies for patients in diverse clinical situations.7–9
Learn more
OVERVIEW OF SERVICES
Overview Tissue-based test for solid tumours, based on our analytically and
clinically validated, FDA-approved comprehensive platform† Liquid biopsy test
for solid tumours when tissue biopsy is tissue for analysis, and/or disease
progression is suspected For haematological malignancies and sarcomas
personalised treatment decisions 7,10,12 Opens up the opportunity of
comprehensive genomic profiling with a single blood draw 8,13 For diagnostic,
prognostic and predictive insights to support treatment 9 FFPE Peripheral whole
blood FFPE, peripheral whole blood, bone marrow aspirate Sample type 324 70 >400
Genes Tumour mutational burden (TMB) Microsatellite instability (MSI) EXPLORE
EXPLORE EXPLORE
Learn more Learn more
COMBINED COMMITMENT
As part of our long-standing commitment to pioneering progress in precision
medicine, molecular insights leader Foundation Medicine has become a member of
the Roche Group. Together Roche and Foundation Medicine are bringing
comprehensive genomic profiling to cancer patients around the world, combining
Roche’s expertise and commitment in oncology and Foundation Medicine’s leading
technology, validation and experience in cancer profiling.14
Oncology Molecular insights Precision medicine
Learn more Learn more
*Comprehensive genomic profiling is a tumour testing method that utilises
next-generation sequencing technology to identify all four classes of
alterations across a large set of cancer-related genes (>50) known to drive
cancer across tumour types. Comprehensive genomic profiling is a ‘pan-tumour’
approach, or applicable for use across any type of cancer.
†Clinical validation based on demonstrated concordance with the following
companion diagnostics: cobas® EGFR Mutation Test, Ventana ALK (D5F3) CDx Assay,
Vysis ALK Break-Apart FISH Probe Kit, therascreen® KRAS RGQ PCR Kit, Dako HER2
FISH PharmDx® Kit, cobas® BRAF V600 Mutation Test, THxID® BRAF kit. For more
information, please see the FoundationOne®CDx Technical Specifications available
at: www.rochefoundationmedicine.com/f1cdxtech.
FDA, US Food and Drug Administration. FFPE, formalin-fixed paraffin-embedded.
References
1. Frampton GM et al. Nat Biotechnol 2013; 31: 1023–1031.
2. Drilon A et al. Clin Cancer Res 2015; 21: 3631–3639.
3. Rankin A et al. Oncologist 2016; 21: 1306–1314.
4. Ross JS et al. Cancer 2016; 122: 2654–2662.
5. Suh JH et al. Oncologist 2016; 21: 684–691.
6. Hirshfield KM et al. Oncologist 2016; 21: 1315–1325.
7. FoundationOne®CDx Technical Specifications, 2018. Available at:
www.rochefoundationmedicine.com/f1cdxtech (Accessed March 2019).
8. FoundationOne®Liquid Technical Specifications, 2018. Available at:
https://www.foundationmedicine.com/genomic-testing/foundation-one-liquid
(Accessed March 2019).
9. FoundationOne®Heme Technical Specifications, 2017. Available at:
www.foundationmedicine.com/genomic-testing/foundation-one-heme (Accessed
March 2019).
10. FoundationOne®CDx FDA Approval, 2017. Available at:
https://www.accessdata.fda.gov/cdrh_docs/pdf17/P170019a.pdf (Accessed March
2019).
11. FoundationOne®CDx Sample Report, 2018. Available at:
www.rochefoundationmedicine.com/reporting (Accessed March 2019).
12. FoundationOne®CDx FDA Approval Press Release, 2017. Available at:
https://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm587273.htm
(Accessed March 2019).
13. Clark TA et al. J Mol Diagn 2018; 20: 686–702.
14. Roche Media Release, 2018. Available at:
https://www.roche.com/media/releases/med-cor-2018-06-19.htm (Accessed March
2019).
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* Precision Medicine
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Precision Medicine
What is Precision Medicine?
Comprehensive genomic profiling
Our services
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FoundationOne CDx
FoundationOne Liquid CDx
FoundationOne Heme
About us
Roche Foundation Medicine
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COPYRIGHT @ 2019 ALL RIGHTS RESERVED
PR/FMI/1902/0006 | Date of preparation: March 2019
Legal Entity: Roche Singapore Pte Ltd
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